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    Mononucleosis Diagnostic Market

    ID: MRFR/MED/20322-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Mononucleosis Diagnostic Market Research Report Information By Test Type (Epstein Barr Virus (EBV) Antibody Test, Monospot Test, and Complete Blood Count Test), By End-User (Hospitals, Laboratories, and Others), And By Region (North America, Europe, Asia-Pacific, And Rest of The World) –Market Forecast Till 2035.

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    Mononucleosis Diagnostic Market Infographic
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    Mononucleosis Diagnostic Market Summary

    The Global Mononucleosis Diagnostic Market is projected to grow from 1.80 USD Billion in 2024 to 4.46 USD Billion by 2035.

    Key Market Trends & Highlights

    Mononucleosis Diagnostic Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 8.01 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 4.2 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 1.80 USD Billion, reflecting the current demand for diagnostic solutions.
    • Growing adoption of advanced diagnostic technologies due to increasing awareness of mononucleosis is a major market driver.

    Market Size & Forecast

    2024 Market Size 1.80 (USD Billion)
    2035 Market Size 4.46 (USD Billion)
    CAGR (2025-2035) 8.60%

    Major Players

    Abbott (U.S.), DAIICHI SANKYO COMPANY, LIMITED (Japan), Weizmann Institute of Science (Israel), Biotest AG (Germany), Bio-Rad Laboratories, Inc. (U.S.), Genzyme (U.S.), F.Hoffmann-La Roche Ltd (Switzerland), Johnson & Johnson Services, Inc. (U.S.), BD (U.S.), DiaSorin Molecular LLC (U.S.)

    Mononucleosis Diagnostic Market Trends

    Rising incidences of infectious mononucleosis (IM) and the increasing adolescent population are driving the market growth.

    Market CAGR for Mononucleosis Diagnostic is driven by the rising incidences of infectious mononucleosis (IM) and the increasing adolescent population. According to the Centers for Disease Control and Prevention, there were approximately 23,780 incidents of infectious mononucleosis (IM) between 2002 and 2018, with an ordinary prevalence rate of 104.2 cases per 100,000 person-years. The incidence of IM diagnoses became highest in many of the youngest age agencies and reduced with age. It happened to be so.

    White non-Hispanic service members had higher IM diagnoses (per 100,000 years) compared to other racial/ethnic groups, with IM diagnoses among recruits being other classified employees 3.4 times the name (106 per 100,000 years ) and policing 5.6 times (64.7 per 100,000 p-years) The increased incidence of infectious (IM) nuclear mononuclear disease leads to a higher demand for diagnosis, leading to an increase.

    Since mononucleosis is most common in teens and adults, an increasing number of adolescents worldwide is also a major driver of the market's growth. Asia is home to more than half of the world's adolescent population. More adolescents live in South Asia than any other region—nearly 350 million. With more than 300 million, East Asia and the Pacific come in second. Any of these regions has a much larger teenage population than any other place in the world. World Health Organisation (WHO) research estimates that there are approximately 1.2 billion adolescents (10–19 years old) around the world.

    Adolescents account for 25% of the population in some countries, and this percentage is expected to increase through 2050, mostly in low- and middle-income countries (LMICs), where close to 90% of 10- to 19-year-olds live. As a result, it is anticipated that throughout the projection period, demand for the Mononucleosis Diagnostic Market will increase due to rising incidences of infectious mononucleosis (IM) and the Increasing adolescent population. Thus, driving the Mononucleosis Diagnostic Market revenue.

    The increasing prevalence of infectious mononucleosis among adolescents and young adults necessitates enhanced diagnostic capabilities to ensure timely and accurate identification of the disease.

    Centers for Disease Control and Prevention (CDC)

    Mononucleosis Diagnostic Market Drivers

    Market Growth Projections

    Growing Healthcare Expenditure

    The Global Mononucleosis Diagnostic Market Industry is positively influenced by the increasing healthcare expenditure observed globally. Governments and private sectors are investing more in healthcare infrastructure, which includes diagnostic services. This trend is particularly evident in developing regions, where improved access to healthcare facilities and diagnostic tools is becoming a priority. As healthcare budgets expand, the availability of diagnostic tests for mononucleosis is likely to increase, facilitating earlier diagnosis and treatment. This growth in healthcare spending is projected to support a compound annual growth rate of 8.01% from 2025 to 2035, further enhancing market prospects.

    Increased Awareness and Education

    Increased awareness and education regarding mononucleosis contribute significantly to the growth of the Global Mononucleosis Diagnostic Market Industry. Public health campaigns and educational initiatives aimed at informing the population about the symptoms and transmission of mononucleosis are essential. As individuals become more knowledgeable about the disease, they are more likely to seek medical attention and diagnostic testing. This heightened awareness can lead to earlier detection and treatment, ultimately improving health outcomes. Consequently, the market is expected to benefit from this trend, as more individuals pursue diagnostic services.

    Emerging Markets and Demographic Shifts

    Emerging markets and demographic shifts are pivotal drivers of the Global Mononucleosis Diagnostic Market Industry. As populations in developing countries grow and urbanization increases, the demand for healthcare services, including diagnostic testing, is expected to rise. Younger populations in these regions are particularly susceptible to infectious diseases, including mononucleosis. Consequently, the expansion of healthcare access in these markets may lead to a surge in diagnostic testing. This demographic trend, coupled with rising incomes, is likely to create new opportunities for market players, fostering growth in the coming years.

    Rising Prevalence of Infectious Diseases

    The Global Mononucleosis Diagnostic Market Industry is experiencing growth due to the increasing prevalence of infectious diseases, particularly among adolescents and young adults. Infectious mononucleosis, often caused by the Epstein-Barr virus, is becoming more common, leading to a heightened demand for accurate diagnostic tools. As the global population ages and lifestyles change, the incidence of such diseases is likely to rise. This trend necessitates the development of advanced diagnostic methods, which could significantly contribute to the market's expansion. With the market projected to reach 1.8 USD Billion in 2024, the focus on effective diagnostics is paramount.

    Technological Advancements in Diagnostic Tools

    Technological innovations play a crucial role in the Global Mononucleosis Diagnostic Market Industry, as advancements in laboratory techniques and diagnostic equipment enhance the accuracy and speed of testing. The introduction of rapid diagnostic tests and molecular techniques, such as PCR, allows for quicker identification of mononucleosis, thereby improving patient outcomes. These innovations not only streamline the diagnostic process but also reduce the burden on healthcare systems. As the market evolves, the integration of artificial intelligence and machine learning in diagnostics may further revolutionize the industry, potentially driving the market value to 4.2 USD Billion by 2035.

    Market Segment Insights

    Mononucleosis Diagnostic Market Test Type Insights

    The Mononucleosis Diagnostic Market segmentation, based on Test Type, includes Epstein Barr Virus (EBV) Antibody Test, Monospot Test, and Complete Blood Count Test. The monospot test segment dominated the market, accounting for 58% of market revenue. As revealed by a study published in the Clinical Journal of Sports Medicine in November 2021, in its mono spot test, the test had a sensitivity and specificity of 80% and 91%, respectively, and the resistance tests had sensitivities of 47-83%. A large connective shows the levels of transaminases and acute infectious mononucleosis, which may be used to diagnose the disease.

    The most dependable way to diagnose IM is the presence of a positive mono spot in the mononucleosis test. Consequently, the careful placing of high sensitivity and specificity is believed to provide the necessary drive for the further development of this field in the next few years. Even though mature people with Epstein-Barr virus as the first infection of the mononucleosis disease group can hardly be found, infectious mononucleosis is mostly recognized with overnight fever and sore throat for adults. Since these diseases are more prevalent among young peers, they are expected to be the ones to drive the market.

    Figure 1:  Mononucleosis Diagnostic Market, by Test Type, 2023 & 2032 (USD Billion)

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Mononucleosis Diagnostic Market End-User Insights

    The Mononucleosis Diagnostic Market segmentation, based on the End-User, includes Hospitals, Laboratories, and Others. The Hospitals segment dominated the market, accounting for 58% of market revenue. Hospitals are also well-equipped with diagnostic facilities that are almost painlessly equipped, like lab work and other crucial tests for NV that are needed in the diagnosis of mononucleosis. Facilities like this help physicians perform precise and timely diagnoses, which is thereby responsible for the growth of this market segment.

    Get more detailed insights about Mononucleosis Diagnostic Market

    Regional Insights

    By region, the study provides market insights into North America, Europe, Asia-Pacific, and Rest of the World. The anticipated expansion of the Mononucleosis Diagnostic market in North America can be attributed to several key factors. More promising factors are the relatively well-developed healthcare infrastructure and high adoption of advanced diagnosis techniques, which are the region's key points to higher growth. U.S. healthcare spending grew 4.1 percent in 2022, reaching $4.5 trillion or $13,493 per person.

    As a share of the nation's Gross Domestic Product, health spending accounted for 17.3 percent. This region segment`s mononucleosis diagnostic market is being driven by two major factors: the rising need for immediate and accurate diagnosis, including the high public uptake of the necessity for fast diagnosis and treatment.

    Further, the major countries studied in the market report are the US, Canada, Germany, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 2:  MONONUCLEOSIS DIAGNOSTIC MARKET SHARE BY REGION 2023 (USD Billion)

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Europe's Mononucleosis Diagnostic Market accounts for the second-largest market share. One virus in particular that causes mononucleosis, the most popular disease known as "the kissing disease" or "mono," is called Epstein-Barr Virus (EBV). In 2022, the number of infectious mononucleosis cases in Spain amounted to nearly 26,400, up from 18,700 cases reported a year earlier. The highest number of mononucleosis cases in the European country was registered in 2016, after reaching approximately 46,300 thousand infections. This influenza virus has increased in prevalence across Europe, causing more and more demand for diagnostic tests.

    Further, the German Mononucleosis Diagnostic Market held the largest market share, and the UK Mononucleosis Diagnostic Market was the fastest-growing market in the European region.

    The Asia-Pacific Mononucleosis Diagnostic Market is expected to grow at the fastest CAGR from 2024 to 2032. As per the United Nations Children's Fund, almost 25% of all teens worldwide, or 329 million adolescents, will reside in the East Asia and Pacific region as of January 2022. The substantial number of young people suggests that there is a considerable need for diagnostic testing for mononucleosis. Furthermore, according to a November 2022 Verywell Health article, between 25% and 50% of American children from poorer socioeconomic classes would have had EBV by the time they were 4 years old.

    Furthermore, following an EBV infection, 75% of young adults will receive a mono diagnosis. Throughout the projection period, the rising cases of mononucleosis and EBV in the region are expected to drive market growth. Moreover, China’s Mononucleosis Diagnostic Market held the largest market share, and the Indian Mononucleosis Diagnostic Market was the fastest-growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    Leading market players are investing heavily in research and development to expand their product lines, which will help the Mononucleosis Diagnostic market grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, the Mononucleosis Diagnostic industry must offer cost-effective items.

    Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the Mononucleosis Diagnostic industry to benefit clients and increase the market sector. In recent years, the Mononucleosis Diagnostic industry has offered some of the most significant advantages to the medical field. Major players in the Mononucleosis Diagnostic Market, including Abbott (U.S.), DAIICHI SANKYO COMPANY, LIMITED (Japan), Weizmann Institute of Science (Israel), Biotest AG (Germany), Bio-Rad Laboratories, Inc. (U.S.), Genzyme (U.S.), F.

    Hoffmann-La Roche Ltd (Switzerland), Johnson & Johnson Services, Inc. (U.S.), BD (U.S.), DiaSorin Molecular LLC (U.S.) are attempting to increase market demand by investing in research and development operations.

    Abbott discovers, manufactures, and distributes a wide range of healthcare products, such as adult and pediatric nutritional items, branded generic medications, and diagnostic equipment and tests. Heart failure, electrophysiology, rhythm management, vascular and structural heart devices, and neuromodulation devices are among the medical products that the company also sells. The company offers dietary supplements, nutrition products, and minerals. It operates manufacturing plants all around the world and maintains research and development centers in the US, Colombia, India, Singapore, Spain, and the UK. The company markets its products across Europe, Asia-Pacific, Africa, Latin America, the Middle East, and North America.

    The US headquarters of Abbott is located in Abbott Park, Illinois. In 2021, Abbott Laboratories purchased Walk Vascular, LLC, a medical device company specializing in the development of minimally invasive devices for vascular disease, to expand its portfolio in the vascular sector.

    A holding company, Daiichi Sankyo Co Ltd, is responsible for pharmaceutical product development, manufacturing, and marketing. The company provides a broad range of over-the-counter (OTC), prescription, and vaccination drugs. Its product line includes medications for cancers of all kinds as well as conditions including diabetes, metabolic, neurological, nephrological, cardiovascular, and infectious disorders. The company also conducts research on immunological disorders and uncommon diseases in addition to cancer. Through its group companies and an extensive network of medical professionals, Daiichi Sankyo promotes its products. It operates in Europe, Asia, South and Central America, and North America.

    Tokyo, Japan, is home to Daiichi Sankyo's headquarters.

    Key Companies in the Mononucleosis Diagnostic Market market include

    Industry Developments

    • Q2 2024: Abbott launches new rapid mononucleosis test for point-of-care settings Abbott announced the launch of a new rapid diagnostic test for mononucleosis, designed for use in point-of-care settings to deliver results within minutes. The test aims to improve early detection and patient management for suspected cases of mononucleosis.
    • Q1 2024: Roche receives CE mark for new Epstein-Barr virus (EBV) diagnostic assay Roche announced that its new EBV diagnostic assay, which aids in the diagnosis of mononucleosis, has received CE mark approval in Europe. The assay is designed for use on the cobas 6800/8800 systems.
    • Q2 2024: Bio-Rad launches enhanced EBV antibody panel for mononucleosis diagnosis Bio-Rad Laboratories introduced an enhanced EBV antibody panel to improve the accuracy of mononucleosis diagnosis in clinical laboratories. The new panel offers improved sensitivity and specificity for EBV detection.
    • Q3 2024: Johnson & Johnson acquires startup developing next-generation mononucleosis diagnostics Johnson & Johnson announced the acquisition of a biotechnology startup focused on next-generation molecular diagnostics for mononucleosis and other infectious diseases. The acquisition is expected to accelerate J&J's innovation pipeline in infectious disease diagnostics.
    • Q2 2024: BD receives FDA clearance for new mononucleosis rapid test BD announced that it has received FDA clearance for its new rapid mononucleosis test, which provides results in under 10 minutes and is intended for use in both laboratory and point-of-care settings.
    • Q1 2025: DiaSorin Molecular launches multiplex PCR panel including mononucleosis detection DiaSorin Molecular announced the commercial launch of a new multiplex PCR panel that includes detection of Epstein-Barr virus, enabling comprehensive testing for mononucleosis alongside other viral pathogens.
    • Q2 2025: Genzyme opens new manufacturing facility for mononucleosis diagnostic reagents Genzyme inaugurated a new manufacturing facility dedicated to the production of diagnostic reagents for mononucleosis and other infectious diseases, aiming to meet growing global demand.
    • Q1 2024: Weizmann Institute of Science partners with major diagnostics firm to develop advanced mononucleosis test The Weizmann Institute of Science announced a partnership with a leading diagnostics company to co-develop an advanced molecular test for mononucleosis, leveraging novel biomarkers for improved accuracy.
    • Q3 2024: Roche expands global distribution agreement for mononucleosis diagnostic products Roche announced the expansion of its global distribution agreement with a major healthcare distributor to increase the availability of its mononucleosis diagnostic products in emerging markets.
    • Q2 2025: Abbott receives Health Canada approval for new mononucleosis diagnostic assay Abbott announced that its latest mononucleosis diagnostic assay has received approval from Health Canada, enabling its commercial launch across Canadian healthcare facilities.

    Mononucleosis Diagnostic 

    Future Outlook

    Mononucleosis Diagnostic Market Future Outlook

    The Mononucleosis Diagnostic Market is projected to grow at 8.60% CAGR from 2025 to 2035, driven by technological advancements, increasing awareness, and rising healthcare expenditures.

    New opportunities lie in:

    • Develop rapid diagnostic tests to enhance patient access and reduce diagnosis time.
    • Leverage telemedicine platforms for remote consultations and follow-ups in mononucleosis cases.
    • Invest in educational campaigns to raise awareness about mononucleosis symptoms and testing options.

    By 2035, the Mononucleosis Diagnostic Market is expected to achieve substantial growth, reflecting evolving healthcare dynamics.

    Market Segmentation

    Regional Outlook

    North America
    • US
    • Canada
    Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    Asia-Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    Rest of the World
    • Middle East
    • Africa
    • Latin America

    Mononucleosis Diagnostic Market End-User Outlook

    • Hospitals
    • Laboratories
    • Others

    Mononucleosis Diagnostic Market Test Type Outlook

    • Epstein Barr Virus (EBV) Antibody Test
    • Monospot Test
    • Complete Blood Count Test

    Mononucleosis Diagnostic Market Regional Outlook

    North America
    • US
    • Canada
    Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    Asia-Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    Rest of the World
    • Middle East
    • Africa
    • Latin America

    Report Scope

    Mononucleosis Diagnostic Market Report Scope

    Report Attribute/Metric Details
    Market Size 2024 USD 1.8 Billion
    Market Size 2035 4.46 (Value (USD Billion))
    Compound Annual Growth Rate (CAGR) 8.60% (2025 - 2035)
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019-2022
    Market Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Test Type and End-User, and Region
    Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
    Countries Covered The US, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies Profiled Abbott (U.S.), DAIICHI SANKYO COMPANY, LIMITED (Japan), Weizmann Institute of Science (Israel), Biotest AG (Germany), Bio-Rad Laboratories, Inc. (U.S.), Genzyme (U.S.), F. Hoffmann-La Roche Ltd (Switzerland), Johnson & Johnson Services, Inc. (U.S.), BD (U.S.), DiaSorin Molecular LLC (U.S.).
    Key Market Opportunities ·         Technological advancements in diagnostic testing methods for mononucleosis
    Key Market Dynamics ·         The rising prevalence of infectious mononucleosis is driving expansion.
    Market Size 2025 1.95 (Value (USD Billion))

     

    FAQs

    What is the projected growth of the Mononucleosis Diagnostic market?

    The Mononucleosis Diagnostic market is the expected increase in total market value of 4.46 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Mononucleosis Diagnostic market?

    Mononucleosis Diagnostic market size was valued at approximately 1.8 billion USD in 2024. This figure will reach 4.46 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Mononucleosis Diagnostic market?

    Mononucleosis Diagnostic market is expected to grow at a CAGR of 8.6% between 2025 and 2035.

    How much will the Mononucleosis Diagnostic market be worth by 2035?

    Mononucleosis Diagnostic market is expected to be worth of 4.46 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Mononucleosis Diagnostic market perform over the next 10 years?

    Over the next 10 years the Mononucleosis Diagnostic market is expected to shift from usd billion 1.8 to 4.46 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region held the largest market share in the Mononucleosis Diagnostic Market?

    North America had the largest share of the market.

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