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UK Liquid Biopsy Market

ID: MRFR/HC/42975-HCR
200 Pages
Rahul Gotadki
October 2025

UK Liquid Biopsy Market Research Report By Types (Circulating Tumor Cells, Circulating Tumor DNA, Extracellular Vesicles, Others), By Application (Cancer Therapeutic Application, Reproductive Health, Others) and By Sample (Blood Sample, Urine Sample, Other)- Forecast to 2035

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UK Liquid Biopsy Market Summary

As per MRFR analysis, the UK liquid biopsy market Size was estimated at 454.95 USD Million in 2024. The UK liquid biopsy market is projected to grow from 502.81 USD Million in 2025 to 1367.15 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 10.52% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The UK liquid biopsy market is poised for substantial growth driven by technological advancements and increasing demand for personalized medicine.

  • Technological advancements are enhancing the accuracy and efficiency of liquid biopsy tests.
  • The growing demand for personalized medicine is propelling the adoption of liquid biopsy solutions.
  • The oncology segment remains the largest, while the prenatal testing segment is the fastest-growing in the UK market.
  • Rising incidence of cancer and advancements in biomarker discovery are key drivers fueling market expansion.

Market Size & Forecast

2024 Market Size 454.95 (USD Million)
2035 Market Size 1367.15 (USD Million)
CAGR (2025 - 2035) 10.52%

Major Players

Guardant Health (US), Exact Sciences (US), Freenome (US), GRAIL (US), Biocept (US), Sysmex Corporation (JP), Roche Diagnostics (CH), Qiagen (NL), Thermo Fisher Scientific (US)

UK Liquid Biopsy Market Trends

The liquid biopsy market is experiencing notable advancements, driven by the increasing demand for non-invasive diagnostic techniques. This method allows for the detection of cancer and other diseases through the analysis of circulating tumor cells, cell-free DNA, and exosomes in bodily fluids. As healthcare providers seek to enhance patient outcomes, the adoption of liquid biopsy technologies is becoming more prevalent. Furthermore, the integration of artificial intelligence and machine learning into diagnostic processes is likely to improve accuracy and efficiency, thereby fostering growth in this sector. In addition, regulatory bodies in the UK are actively working to establish guidelines that support the safe and effective use of liquid biopsy technologies. This regulatory framework is essential for ensuring that innovations in this field meet the necessary safety and efficacy standards. As a result, the liquid biopsy market is poised for expansion, with ongoing research and development efforts aimed at refining existing technologies and exploring new applications. The potential for personalized medicine, where treatments are tailored to individual patients based on their unique genetic profiles, further underscores the importance of this market in the future of healthcare.

Technological Advancements

Recent innovations in liquid biopsy technologies are enhancing the sensitivity and specificity of tests. These advancements are likely to facilitate earlier detection of diseases, which could lead to improved patient outcomes. The integration of next-generation sequencing and other cutting-edge methodologies is expected to play a crucial role in this evolution.

Regulatory Developments

The establishment of clear regulatory guidelines by UK authorities is fostering a more structured environment for the liquid biopsy market. These regulations aim to ensure that new technologies are safe and effective, which may encourage further investment and research in this area.

Growing Demand for Personalized Medicine

There is an increasing emphasis on personalized medicine within the healthcare sector. Liquid biopsy technologies are well-positioned to support this trend by providing critical insights into individual patient profiles, thereby enabling tailored treatment strategies that could enhance therapeutic efficacy.

UK Liquid Biopsy Market Drivers

Rising Incidence of Cancer

The increasing incidence of cancer in the UK is a primary driver for the liquid biopsy market. With cancer cases projected to rise by approximately 2.5% annually, the demand for non-invasive diagnostic methods is intensifying. Liquid biopsies offer a promising alternative to traditional tissue biopsies, enabling earlier detection and monitoring of cancer progression. This shift towards less invasive procedures aligns with patient preferences and healthcare provider goals, potentially leading to improved patient outcomes. The liquid biopsy market is thus positioned to benefit from this trend, as healthcare systems seek efficient and effective diagnostic solutions to manage the growing cancer burden.

Advancements in Biomarker Discovery

Recent advancements in biomarker discovery are significantly influencing the liquid biopsy market. The identification of novel biomarkers has enhanced the ability to detect various cancers at earlier stages, which is crucial for effective treatment. As research progresses, the integration of these biomarkers into liquid biopsy tests is becoming more prevalent. This trend is expected to drive market growth, as the UK healthcare sector increasingly adopts liquid biopsies for routine cancer screening and monitoring. The potential for liquid biopsies to provide real-time insights into tumor dynamics further underscores their value in personalized medicine, thereby expanding their application in clinical settings.

Regulatory Support for Innovative Diagnostics

Regulatory support for innovative diagnostic solutions is playing a pivotal role in shaping the liquid biopsy market. The UK regulatory framework is increasingly accommodating the introduction of novel liquid biopsy technologies, streamlining the approval process for new tests. This supportive environment encourages companies to invest in the development of advanced liquid biopsy products, knowing that they can navigate regulatory hurdles more efficiently. As a result, the market is likely to witness a surge in the availability of liquid biopsy tests, enhancing patient access to cutting-edge diagnostic options. This trend not only benefits manufacturers but also aligns with the broader goal of improving healthcare outcomes in the UK.

Growing Awareness Among Healthcare Professionals

The growing awareness among healthcare professionals regarding the benefits of liquid biopsies is a crucial driver for the market. As more clinicians recognize the advantages of non-invasive testing methods, the adoption of liquid biopsies is likely to increase. Educational initiatives and training programs are being implemented to inform healthcare providers about the clinical applications and efficacy of liquid biopsies. This heightened awareness is expected to translate into greater utilization of these tests in clinical practice, thereby propelling the liquid biopsy market forward. The shift towards evidence-based medicine further supports this trend, as practitioners seek reliable diagnostic options for their patients.

Increased Investment in Research and Development

Investment in research and development (R&D) within the liquid biopsy market is on the rise, driven by both public and private sectors. The UK government has allocated substantial funding towards cancer research initiatives, which includes the development of innovative liquid biopsy technologies. This financial support is likely to accelerate the introduction of new products and services, enhancing the overall market landscape. Furthermore, collaborations between academic institutions and biotech companies are fostering innovation, leading to the emergence of cutting-edge solutions. As R&D efforts continue to flourish, the liquid biopsy market is expected to expand, offering more sophisticated diagnostic tools to healthcare providers.

Market Segment Insights

By Application: Cancer Diagnosis (Largest) vs. Treatment Monitoring (Fastest-Growing)

In the UK liquid biopsy market, the primary applications include Cancer Diagnosis, Treatment Monitoring, Recurrence Monitoring, Clinical Trials, and Research Applications. Among these, Cancer Diagnosis holds the largest share, reflecting the increasing reliance on non-invasive diagnostics in oncology. Treatment Monitoring, while crucial, has been growing at a faster pace due to rising demand for real-time assessment of patient responses to therapies, leveraging liquid biopsy technology for enhanced patient management. The growth trends indicate a significant shift towards personalized medicine, where liquid biopsies provide actionable insights for tailored treatment plans. The surge in cancer prevalence and the push for early detection tools are key drivers in this market. Concurrently, the integration of liquid biopsy in clinical trials enhances drug development efficiency, further propelling growth across all applications, particularly in treatment monitoring.

Cancer Diagnosis (Dominant) vs. Treatment Monitoring (Emerging)

Cancer Diagnosis is currently the dominant segment within the UK liquid biopsy market, characterized by a robust demand for efficient and non-invasive cancer screening solutions. This application allows for the detection of tumors earlier than conventional methods, significantly impacting patient outcomes. Treatment Monitoring is an emerging segment, gaining traction as healthcare professionals increasingly utilize liquid biopsies to track treatment efficacy in real-time. The need for continuous patient monitoring and the ability to detect treatment resistance early are propelling this segment's growth, promising to reshape the landscape of oncological care in the near future.

By Sample Type: Blood (Largest) vs. Urine (Fastest-Growing)

The market share distribution for the sample types in the UK liquid biopsy market reveals that blood-based assays dominate, claiming a substantial portion of the overall market. Urine samples are rapidly gaining traction, fueled by their non-invasive nature and increasing acceptance among clinicians and patients alike. Other sample types, such as saliva and pleural fluid, hold smaller shares but are essential in specific diagnostic contexts. Growth trends in the sample types indicate a significant shift towards urine-based liquid biopsies, driven by advancements in technology and the growing demand for less invasive testing options. Blood remains pivotal due to its established protocols, but the rising interest in urine assays suggests a changing landscape where patient comfort and ease of sample collection play critical roles in shaping future market dynamics.

Blood (Dominant) vs. Urine (Emerging)

Blood sample testing is the cornerstone of the UK liquid biopsy market, recognized for its reliability and comprehensive information on a range of conditions, particularly cancer. It stands out in terms of clinical usage and ease of sample collection. Conversely, urine as an emerging sample type is making significant strides, boasting advantages like reduced patient discomfort and the ability to capture a unique metabolic profile of diseases. Innovations in urine analysis technologies are enhancing its accuracy and reliability, contributing to its popularity among patients and healthcare providers. As research continues to support its potential, urine may become a vital component of the diagnostic toolkit, challenging blood's dominance.

By Technology: Next Generation Sequencing (Largest) vs. Digital PCR (Fastest-Growing)

In the UK liquid biopsy market, Next Generation Sequencing (NGS) stands out as the largest segment, capturing a significant portion of the market share. Digital PCR follows as a competitive player, gaining traction due to its precision and increasing adoption across clinical laboratories. Microfluidics, Exosome Isolation, and Circulating Tumor Cells also contribute to the overall landscape, but their market shares remain comparatively smaller. The distribution highlights the dominance of NGS while showcasing the growth potential of digital PCR. The growth trends in the UK liquid biopsy market are driven by advances in technology and increasing research investments. The demand for early cancer detection and personalized medicine is propelling the adoption of liquid biopsy techniques. Additionally, the efficiency of tests like NGS enables comprehensive genomic profiling, which is vital for tailored treatment plans. As regulatory approvals enhance market access, digital PCR is rapidly emerging as a preferred choice due to its enhanced sensitivity and quantification capabilities.

Technology: Next Generation Sequencing (Dominant) vs. Digital PCR (Emerging)

Next Generation Sequencing (NGS) is at the forefront of the UK liquid biopsy market, providing large-scale genomic data with high throughput and accuracy. It enables the comprehensive analysis of circulating tumor DNA, making it invaluable for early cancer detection and monitoring treatment response. On the other hand, Digital PCR is establishing itself as an emerging technology, offering unparalleled sensitivity in detecting rare mutations and low-abundance targets. Its ability to deliver quantitative results makes it particularly attractive for precision medicine. As more diagnostic labs adopt these technologies, the interplay between NGS's broad capabilities and Digital PCR's precision will shape future advancements in non-invasive diagnostic methodologies.

By End Use: Hospitals (Largest) vs. Diagnostic Laboratories (Fastest-Growing)

In the UK liquid biopsy market, hospitals dominate the end use segment, accounting for a significant share due to their extensive patient base and advanced diagnostic capabilities. They serve as essential hubs for the adoption of liquid biopsy technologies, facilitating early cancer detection and personalized treatment plans. Diagnostic laboratories, while smaller in market share, are rapidly gaining traction as they enhance their molecular diagnostic services, focusing on innovative solutions that cater to specific cancer types. Growth trends in this segment are being driven by increasing investments in healthcare infrastructure, a rise in cancer prevalence, and an emphasis on early diagnosis. Hospitals are expanding their capabilities through partnerships and advanced technologies, while diagnostic laboratories are innovating with streamlined workflows and enhanced precision. Research institutes and pharmaceutical companies play complementary roles, contributing to advancements and validations of liquid biopsy methods, thus fostering a dynamic ecosystem that supports both patient care and research development.

Hospitals (Dominant) vs. Diagnostic Laboratories (Emerging)

Hospitals represent a dominant force in the UK liquid biopsy market, leveraging their extensive resources and infrastructure to provide comprehensive patient care. They possess the ability to integrate liquid biopsy technologies into clinical practice effectively, allowing for widespread adoption. In contrast, diagnostic laboratories are emerging as critical players by offering specialized services that enhance patient outcomes. They focus on innovation and efficiency in testing, utilizing cutting-edge technology to process samples with greater accuracy. Diagnostic laboratories are increasingly collaborating with hospitals and research institutions, allowing for quicker turnaround times and improved access to advanced diagnostic options. Together, these segments reflect a dynamic relationship that is essential for the future of liquid biopsy applications.

Get more detailed insights about UK Liquid Biopsy Market

Key Players and Competitive Insights

The liquid biopsy market is currently characterized by a dynamic competitive landscape, driven by advancements in technology and increasing demand for non-invasive diagnostic solutions. Key players are actively engaging in strategic initiatives to enhance their market presence and operational capabilities. For instance, Guardant Health (US) has positioned itself as a leader in precision oncology, focusing on the development of comprehensive genomic profiling tests. Meanwhile, Roche Diagnostics (CH) emphasizes innovation through its robust R&D efforts, particularly in liquid biopsy assays that cater to various cancer types. These strategies collectively contribute to a competitive environment that is increasingly focused on technological advancement and patient-centric solutions.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The market structure appears moderately fragmented, with several players vying for market share. This fragmentation is indicative of a competitive environment where innovation and strategic partnerships play crucial roles in shaping market dynamics. The collective influence of key players, such as Thermo Fisher Scientific (US) and Qiagen (NL), further underscores the importance of collaboration and technological integration in driving growth.

In October 2025, Thermo Fisher Scientific (US) announced a strategic partnership with a leading UK-based healthcare provider to enhance the accessibility of its liquid biopsy solutions. This collaboration aims to streamline the integration of advanced diagnostic tools into clinical workflows, thereby improving patient outcomes. The strategic importance of this partnership lies in its potential to expand Thermo Fisher's market reach while simultaneously addressing the growing demand for personalized medicine in the UK.

In September 2025, Qiagen (NL) launched a new liquid biopsy test designed to detect minimal residual disease in cancer patients. This innovative product is expected to significantly enhance the monitoring of treatment efficacy and recurrence risk. The introduction of this test reflects Qiagen's commitment to advancing precision medicine and underscores the increasing importance of liquid biopsies in clinical oncology.

In August 2025, Roche Diagnostics (CH) unveiled a new digital platform aimed at integrating liquid biopsy data with electronic health records. This initiative is poised to facilitate real-time data sharing among healthcare providers, thereby enhancing decision-making processes in cancer treatment. The strategic significance of this digital transformation lies in its potential to improve patient management and foster collaborative care models.

As of November 2025, current competitive trends in the liquid biopsy market are heavily influenced by digitalization, sustainability, and the integration of artificial intelligence (AI) into diagnostic processes. Strategic alliances are increasingly shaping the landscape, enabling companies to leverage complementary strengths and enhance their technological capabilities. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition towards a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize R&D and strategic partnerships will be better positioned to thrive in an increasingly complex market.

Key Companies in the UK Liquid Biopsy Market market include

Industry Developments

The UK Liquid Biopsy Market has witnessed significant developments in recent months, driven by an increasing focus on non-invasive cancer diagnostics. Companies like OncoOne and Guardant Health are actively advancing their technologies, contributing to a surge in innovation within the sector. Illumina has focused on expanding its capabilities in next-generation sequencing, enhancing its position in the UK market.

Notably, in February 2023, Thermo Fisher Scientific announced an agreement to acquire a leading liquid biopsy company to broaden its Oncology Information Systems portfolio, which aims to strengthen its influence in the UK and European markets. Recent reports indicate that the UK government is providing substantial funding to foster research in liquid biopsy technologies, aligning with the nation’s push towards personalized medicine. In terms of growth, the UK liquid biopsy market is projected to continue its robust expansion, with expectations to reach a valuation of 1 billion by 2025, signifying the increasing acceptance of liquid biopsies in routine clinical practice.

Additionally, F. Hoffmann-La Roche and Exact Sciences have been noted for their efforts to enhance test sensitivity and specificity, further driving market dynamics and improving patient outcomes.

Future Outlook

UK Liquid Biopsy Market Future Outlook

The Liquid Biopsy Market is projected to grow at a 10.52% CAGR from 2024 to 2035, driven by technological advancements, increasing cancer prevalence, and demand for non-invasive diagnostics.

New opportunities lie in:

  • Development of AI-driven analytics platforms for enhanced diagnostic accuracy.
  • Expansion of liquid biopsy applications in early-stage cancer detection.
  • Partnerships with healthcare providers for integrated testing solutions.

By 2035, the liquid biopsy market is expected to achieve substantial growth, positioning itself as a cornerstone of modern diagnostics.

Market Segmentation

UK Liquid Biopsy Market End Use Outlook

  • Hospitals
  • Diagnostic Laboratories
  • Research Institutes
  • Pharmaceutical Companies

UK Liquid Biopsy Market Technology Outlook

  • Next Generation Sequencing
  • Digital PCR
  • Microfluidics
  • Exosome Isolation
  • Circulating Tumor Cells

UK Liquid Biopsy Market Application Outlook

  • Cancer Diagnosis
  • Treatment Monitoring
  • Recurrence Monitoring
  • Clinical Trials
  • Research Applications

UK Liquid Biopsy Market Sample Type Outlook

  • Blood
  • Urine
  • Saliva
  • Pleural Fluid
  • Cerebrospinal Fluid

Report Scope

MARKET SIZE 2024 454.95(USD Million)
MARKET SIZE 2025 502.81(USD Million)
MARKET SIZE 2035 1367.15(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 10.52% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Guardant Health (US), Exact Sciences (US), Freenome (US), GRAIL (US), Biocept (US), Sysmex Corporation (JP), Roche Diagnostics (CH), Qiagen (NL), Thermo Fisher Scientific (US)
Segments Covered Application, Sample Type, Technology, End Use
Key Market Opportunities Advancements in non-invasive cancer diagnostics drive growth in the liquid biopsy market.
Key Market Dynamics Technological advancements and regulatory support drive growth in the liquid biopsy market, enhancing diagnostic capabilities.
Countries Covered UK

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FAQs

What is the projected market size of the UK Liquid Biopsy Market in 2024?

The UK Liquid Biopsy Market is expected to be valued at 455.0 USD Million in 2024.

What will be the market size of the UK Liquid Biopsy Market by 2035?

By 2035, the UK Liquid Biopsy Market is expected to reach a valuation of 1378.0 USD Million.

What is the expected compound annual growth rate (CAGR) for the UK Liquid Biopsy Market from 2025 to 2035?

The expected CAGR for the UK Liquid Biopsy Market from 2025 to 2035 is 10.598%.

Which segment of the UK Liquid Biopsy Market is anticipated to hold the largest market share by 2035?

Circulating Tumor Cells are projected to be valued at 385.0 USD Million by 2035, holding a significant market share.

What is the expected market size for Circulating Tumor DNA in the UK Liquid Biopsy Market in 2024?

The market size for Circulating Tumor DNA is anticipated to be 170.0 USD Million in 2024.

Who are the key players in the UK Liquid Biopsy Market?

Major players in the market include OncoOne, NeoGenomics, Illumina, and Guardant Health among others.

What is the expected market size for Extracellular Vesicles by 2035?

Extracellular Vesicles are anticipated to reach a market size of 280.0 USD Million by 2035.

What opportunities exist within the UK Liquid Biopsy Market for emerging technologies?

Emerging trends may drive the market growth as innovative technologies and methodologies are developed.

What challenges does the UK Liquid Biopsy Market face moving forward?

The market may face challenges related to regulatory hurdles and competition from traditional biopsy methods.

What is the anticipated market value for the 'Others' category in the UK Liquid Biopsy Market in 2024?

The 'Others' category is expected to be valued at 70.0 USD Million in 2024.

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