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South Korea Liquid Biopsy Market

ID: MRFR/HC/42976-HCR
200 Pages
Rahul Gotadki
October 2025

South Korea Liquid Biopsy Market Research Report By Types (Circulating Tumor Cells, Circulating Tumor DNA, Extracellular Vesicles, Others), By Application (Cancer Therapeutic Application, Reproductive Health, Others), and By Sample (Blood Sample, Urine Sample, Other)- Forecast to 2035

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South Korea Liquid Biopsy Market Infographic
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South Korea Liquid Biopsy Market Summary

As per MRFR analysis, the South Korea liquid biopsy market Size was estimated at 181.98 USD Million in 2024. The South Korea liquid biopsy market is projected to grow from 201.18 USD Million in 2025 to 548.76 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 10.55% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South Korea liquid biopsy market is poised for substantial growth driven by technological advancements and increasing demand for personalized medicine.

  • Technological advancements are enhancing the accuracy and efficiency of liquid biopsy tests.
  • The largest segment in the South Korea liquid biopsy market is the oncology segment, while the fastest-growing segment is the prenatal testing segment.
  • Regulatory support is fostering innovation and adoption of liquid biopsy technologies in clinical settings.
  • Rising incidence of cancer and advancements in genomic technologies are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 181.98 (USD Million)
2035 Market Size 548.76 (USD Million)
CAGR (2025 - 2035) 10.55%

Major Players

Guardant Health (US), Exact Sciences (US), GRAIL (US), Freenome (US), Biocept (US), Foundation Medicine (US), Roche (CH), Thermo Fisher Scientific (US), Illumina (US)

South Korea Liquid Biopsy Market Trends

The liquid biopsy market in South Korea is experiencing notable advancements, driven by increasing demand for non-invasive diagnostic methods. This trend is largely attributed to the growing prevalence of cancer and the need for early detection. Liquid biopsies offer a promising alternative to traditional tissue biopsies, as they can provide critical information about tumor dynamics through the analysis of circulating tumor DNA (ctDNA) and other biomarkers. Furthermore, the South Korean healthcare system is increasingly adopting innovative technologies, which enhances the accessibility and efficiency of liquid biopsy tests. Regulatory support and investment in research and development are also contributing to the market's growth, as stakeholders recognize the potential of these diagnostic tools in improving patient outcomes. In addition, the liquid biopsy market is likely to benefit from collaborations between academic institutions and biotechnology firms. These partnerships may facilitate the development of novel assays and technologies tailored to the specific needs of the South Korean population. Moreover, as awareness of personalized medicine continues to rise, the demand for liquid biopsy tests is expected to increase. This shift towards precision diagnostics aligns with the broader trends in healthcare, where tailored treatment plans are becoming more prevalent. Overall, the liquid biopsy market in South Korea appears poised for significant growth, driven by technological advancements and a supportive regulatory environment.

Technological Advancements

The liquid biopsy market is witnessing rapid technological innovations, particularly in the development of more sensitive and specific assays. These advancements enable the detection of minimal residual disease and facilitate real-time monitoring of treatment responses. As technology evolves, the accuracy and reliability of liquid biopsy tests are expected to improve, further driving their adoption in clinical settings.

Regulatory Support

Regulatory bodies in South Korea are increasingly recognizing the importance of liquid biopsy tests in cancer management. This support is likely to streamline the approval processes for new diagnostic tools, encouraging more companies to invest in research and development. As regulations become more favorable, the market may see an influx of innovative products that enhance patient care.

Growing Demand for Personalized Medicine

There is a rising trend towards personalized medicine in South Korea, which emphasizes tailored treatment strategies based on individual patient profiles. Liquid biopsies play a crucial role in this paradigm shift, as they provide essential insights into tumor biology. The increasing focus on personalized approaches in oncology is expected to drive the demand for liquid biopsy tests, aligning with the broader healthcare trends.

South Korea Liquid Biopsy Market Drivers

Rising Incidence of Cancer

The increasing incidence of cancer in South Korea is a pivotal driver for the liquid biopsy market. With cancer being one of the leading causes of mortality, the demand for early detection and monitoring solutions is surging. Liquid biopsies offer a non-invasive alternative to traditional tissue biopsies, enabling timely diagnosis and treatment adjustments. According to recent statistics, cancer cases in South Korea are projected to rise by approximately 3.5% annually, which underscores the urgent need for innovative diagnostic tools. This trend is likely to propel the liquid biopsy market forward, as healthcare providers seek efficient methods to manage cancer care. The liquid biopsy market is thus positioned to benefit from this growing patient population, as it aligns with the healthcare system's focus on improving patient outcomes through advanced diagnostic technologies.

Advancements in Genomic Technologies

Technological innovations in genomic sequencing and analysis are significantly influencing the liquid biopsy market. The advent of next-generation sequencing (NGS) has enhanced the sensitivity and specificity of liquid biopsies, allowing for the detection of minimal residual disease and genetic mutations. In South Korea, the integration of these advanced technologies is expected to drive market growth, as healthcare providers increasingly adopt liquid biopsy solutions for cancer diagnostics. The liquid biopsy market is witnessing a shift towards more personalized approaches, with genomic insights enabling tailored treatment plans. As the cost of genomic testing continues to decrease, it is anticipated that the adoption of liquid biopsies will expand, further solidifying their role in modern oncology practices.

Regulatory Support for Innovative Diagnostics

Regulatory support for innovative diagnostic solutions is a significant driver for the liquid biopsy market. In South Korea, regulatory bodies are increasingly recognizing the potential of liquid biopsies in transforming cancer diagnostics. Streamlined approval processes and favorable policies are encouraging the development and commercialization of liquid biopsy tests. This supportive regulatory environment is likely to enhance the liquid biopsy market, as it facilitates quicker access to cutting-edge diagnostic tools for healthcare providers. As regulations evolve to accommodate advancements in technology, the market is expected to expand, providing patients with more options for early detection and personalized treatment.

Growing Awareness Among Healthcare Professionals

The increasing awareness and education among healthcare professionals regarding the benefits of liquid biopsies are driving market growth. As clinicians become more informed about the advantages of non-invasive testing methods, the adoption of liquid biopsy solutions is likely to rise. In South Korea, educational programs and workshops are being implemented to enhance understanding of liquid biopsy applications in oncology. This trend is expected to foster greater acceptance of liquid biopsies in clinical practice, thereby expanding the liquid biopsy market. Enhanced knowledge among healthcare providers may lead to improved patient outcomes, as timely and accurate diagnostics become more accessible.

Increased Investment in Research and Development

Investment in research and development (R&D) within the liquid biopsy market is a crucial driver of growth. South Korea's commitment to advancing healthcare technologies has led to substantial funding for innovative diagnostic solutions. Government initiatives and private sector investments are fostering an environment conducive to the development of novel liquid biopsy tests. This influx of capital is likely to accelerate the introduction of new products and technologies, enhancing the overall capabilities of the liquid biopsy market. As R&D efforts continue to evolve, the market is expected to witness a surge in innovative applications, including the detection of various cancers and other diseases, thereby expanding its reach and impact.

Market Segment Insights

By Application: Cancer Diagnosis (Largest) vs. Treatment Monitoring (Fastest-Growing)

In the South Korea liquid biopsy market, Cancer Diagnosis currently holds the largest share, indicating its critical role in early detection and patient outcomes. Following closely, Treatment Monitoring is emerging as a significant player, showcasing a shift towards continuous patient management and personalized treatment strategies. Both segments demonstrate a vibrant competitive landscape, attracting specialized companies focusing on innovative technologies. Growth trends in this market are driven by advancements in genomic technologies and the increasing prevalence of cancer, which necessitate more efficient diagnostic and monitoring solutions. Furthermore, rising healthcare expenditures combined with a greater emphasis on early detection methods are propelling the demand for liquid biopsy applications. The positive reception of these methods in clinical settings reinforces their vital importance in future cancer management strategies.

Cancer Diagnosis (Dominant) vs. Treatment Monitoring (Emerging)

Cancer Diagnosis stands as the dominant application within the South Korea liquid biopsy market, capitalizing on the urgent need for effective screening tools that can detect malignancies at their nascent stages. This segment thrives on its ability to improve patient survival rates by enabling timely interventions. In contrast, Treatment Monitoring is emerging rapidly, focusing on the dynamic assessment of therapeutic efficacy and adjustments based on real-time biomarker analysis. This segment benefits from the increasing recognition of liquid biopsies as a less invasive option, paving the way for better patient experiences and outcomes. Together, these segments represent a complementary approach to cancer management, balancing diagnosis with ongoing care.

By Sample Type: Blood (Largest) vs. Urine (Fastest-Growing)

In the South Korea liquid biopsy market, Blood samples hold the largest market share among various sample types, indicating a strong preference for this method due to its established efficacy and reliability in detecting biomarkers. Urine samples, while smaller in market share, are gaining traction rapidly, reflecting a shift towards less invasive testing options that enhance patient comfort and compliance. The growth trends in this segment are driven by advancements in liquid biopsy technologies that improve detection capabilities and the rising demand for non-invasive diagnostic methods. Urine samples are becoming increasingly recognized for their potential in cancer diagnostics, contributing to their status as the fastest-growing segment. This reflects broader trends toward personalized medicine and early detection in oncology, priorities that are influencing research and development across sample types.

Blood (Dominant) vs. Urine (Emerging)

Blood samples are the dominant choice in the South Korea liquid biopsy market, primarily due to their efficiency in providing comprehensive genomic information relevant to various cancers. This method benefits from a well-established protocol and extensive clinical validation, making it a trusted option among healthcare professionals. On the other hand, Urine samples represent an emerging trend, driven by a growing body of research supporting their utility in non-invasive cancer screening. As technological advancements continue to enhance the sensitivity and specificity of urine-based tests, their market position is expected to strengthen, appealing to a broader patient demographic and healthcare providers seeking cost-effective alternatives.

By Technology: Next Generation Sequencing (Largest) vs. Digital PCR (Fastest-Growing)

In the South Korea liquid biopsy market, the market share is significantly skewed towards Next Generation Sequencing, which commands a substantial portion of the overall market. Digital PCR also plays a critical role in the sector, demonstrating a growing presence and capturing interest among healthcare professionals. Microfluidics, Exosome Isolation, and Circulating Tumor Cells are smaller segments that contribute to the market but are overshadowed by these two key players. Growth trends in this segment are largely driven by innovations in diagnostic technologies, with Next Generation Sequencing paving the way due to its accuracy and efficiency. Digital PCR, on the other hand, is gaining traction due to increasing demand for precise quantification in cancer diagnostics. The continued investment in research and development is fueling advancements that are expected to enhance the capabilities of these technologies further, shaping the competitive landscape.

Technology: Next Generation Sequencing (Dominant) vs. Digital PCR (Emerging)

Next Generation Sequencing stands as the dominant player in the South Korea liquid biopsy market, leveraging its ability to provide comprehensive genomic data with minimal sample amounts. This technology enables rapid analysis of genetic material, which is crucial for early cancer detection and personalized treatment strategies. Digital PCR, meanwhile, is emerging as a significant alternative, offering unparalleled precision in quantifying low-abundance targets. This makes it particularly valuable in liquid biopsy applications where high sensitivity is required. Both technologies are marked by advancements in laboratory setups and increasing applications across clinical research and diagnostics, highlighting a robust competitive environment.

By End Use: Hospitals (Largest) vs. Diagnostic Laboratories (Fastest-Growing)

In the South Korea liquid biopsy market, hospitals represent the largest segment, holding a significant share due to their comprehensive healthcare services and advanced diagnostic technologies. This segment benefits from an increasing demand for precision medicine, with patients relying on hospitals for rapid and accurate testing. On the other hand, diagnostic laboratories are emerging as the fastest-growing segment, driven by the rising trend of early detection of diseases and the integration of liquid biopsy techniques into routine diagnostics. Their role in supporting personalized healthcare solutions significantly contributes to their growth. The growth trends in this segment are primarily fueled by technological advancements and an increased focus on non-invasive diagnostic methods. Hospitals continue to invest in state-of-the-art liquid biopsy technologies to enhance patient outcomes, while diagnostic laboratories are expanding their capabilities to provide timely and efficient testing services. Furthermore, partnerships between pharmaceutical companies and these facilities foster innovation and the development of new diagnostic assays, boosting the overall performance of the liquid biopsy market in South Korea.

Hospitals (Dominant) vs. Diagnostic Laboratories (Emerging)

Hospitals dominate the South Korea liquid biopsy market due to their investments in advanced technologies and comprehensive healthcare offerings. Their extensive infrastructure and patient base allow them to deliver a wide range of diagnostic services, including liquid biopsies for cancer and other diseases. Hospitals are typically at the forefront of research and development, linking clinical needs with groundbreaking innovations. In contrast, diagnostic laboratories are emerging players, focusing on specialized testing services that leverage liquid biopsy technologies. These laboratories are increasingly adopting automation and digital solutions to streamline processes and improve accuracy. As they continue to enhance their service capabilities, diagnostic laboratories are positioning themselves as essential partners in the healthcare ecosystem, complementing the efforts of hospitals in advancing patient care.

Get more detailed insights about South Korea Liquid Biopsy Market

Key Players and Competitive Insights

The liquid biopsy market in South Korea is characterized by a dynamic competitive landscape, driven by technological advancements and increasing demand for non-invasive diagnostic solutions. Key players such as Guardant Health (US), Roche (CH), and Illumina (US) are at the forefront, leveraging innovation and strategic partnerships to enhance their market presence. Guardant Health (US) focuses on expanding its product offerings and enhancing its genomic profiling capabilities, while Roche (CH) emphasizes integrating liquid biopsy solutions into its existing diagnostic portfolio, thereby strengthening its competitive positioning. Illumina (US) is actively pursuing collaborations with local biotech firms to accelerate the development of next-generation sequencing technologies, which collectively shapes a competitive environment that is increasingly reliant on innovation and strategic alliances.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies like Guardant Health (US) and Roche (CH) suggests a trend towards consolidation, as these firms seek to leverage their resources and expertise to capture a larger share of the market.

In October 2025, Guardant Health (US) announced a strategic partnership with a leading South Korean hospital network to implement its liquid biopsy tests in clinical settings. This collaboration is expected to enhance patient access to advanced diagnostic tools, thereby potentially increasing the adoption of liquid biopsy technologies in the region. The strategic importance of this partnership lies in its ability to facilitate real-world evidence generation, which could further validate the efficacy of Guardant's offerings.

In September 2025, Roche (CH) launched a new liquid biopsy assay aimed at improving early cancer detection rates. This product introduction is significant as it aligns with the growing emphasis on early diagnosis in oncology, potentially positioning Roche as a leader in this niche. The launch reflects Roche's commitment to innovation and its strategy to integrate cutting-edge technologies into its diagnostic solutions.

In November 2025, Illumina (US) revealed plans to invest in a new research facility in South Korea, focusing on the development of advanced sequencing technologies. This investment underscores Illumina's long-term commitment to the region and its strategy to enhance its R&D capabilities. The establishment of this facility is likely to foster innovation and collaboration with local research institutions, further solidifying Illumina's competitive edge.

As of November 2025, current trends in the liquid biopsy market include a strong focus on digitalization, sustainability, and the integration of artificial intelligence (AI) into diagnostic processes. Strategic alliances are increasingly shaping the competitive landscape, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition to a focus on technological advancements, innovation, and supply chain reliability. This transition may redefine how companies position themselves in the market, emphasizing the importance of delivering high-quality, reliable solutions.

Key Companies in the South Korea Liquid Biopsy Market market include

Industry Developments

In recent months, the South Korea Liquid Biopsy Market has seen significant developments, particularly in the realms of technology and collaboration, emphasizing the importance of early cancer detection. Companies such as Natera and Illumina are leading advancements in next-generation sequencing technologies, accelerating the availability of liquid biopsy tests for various types of cancer. The collaboration between MD Anderson Cancer Center and South Korean research institutions is enhancing the research landscape, focusing on the validation of liquid biopsy assays.

In terms of mergers and acquisitions, Bristol Myers Squibb recently acquired a stake in a local biotech firm focused on liquid biopsy innovations in January 2023, further illustrating notable strategic moves in the market.

The market valuation for companies like Guardant Health and Myriad Genetics has also seen a rise due to increased healthcare investments and the growing demand for non-invasive tests, which is contributing to the overall growth of the liquid biopsy sector in South Korea. Over the past two to three years, regulatory approvals for new liquid biopsy tests have gained traction, indicating a shifting landscape toward personalized medicine and improved patient outcomes in the oncology field.

Future Outlook

South Korea Liquid Biopsy Market Future Outlook

The Liquid Biopsy Market is projected to grow at a 10.55% CAGR from 2024 to 2035, driven by technological advancements, increasing cancer prevalence, and demand for non-invasive diagnostics.

New opportunities lie in:

  • Development of advanced liquid biopsy platforms for early cancer detection
  • Partnerships with healthcare providers for integrated diagnostic solutions
  • Expansion into personalized medicine through targeted therapy monitoring

By 2035, the liquid biopsy market is expected to achieve substantial growth and innovation.

Market Segmentation

South Korea Liquid Biopsy Market End Use Outlook

  • Hospitals
  • Diagnostic Laboratories
  • Research Institutes
  • Pharmaceutical Companies

South Korea Liquid Biopsy Market Technology Outlook

  • Next Generation Sequencing
  • Digital PCR
  • Microfluidics
  • Exosome Isolation
  • Circulating Tumor Cells

South Korea Liquid Biopsy Market Application Outlook

  • Cancer Diagnosis
  • Treatment Monitoring
  • Recurrence Monitoring
  • Clinical Trials
  • Research Applications

South Korea Liquid Biopsy Market Sample Type Outlook

  • Blood
  • Urine
  • Saliva
  • Pleural Fluid
  • Cerebrospinal Fluid

Report Scope

MARKET SIZE 2024181.98(USD Million)
MARKET SIZE 2025201.18(USD Million)
MARKET SIZE 2035548.76(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)10.55% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies ProfiledGuardant Health (US), Exact Sciences (US), GRAIL (US), Freenome (US), Biocept (US), Foundation Medicine (US), Roche (CH), Thermo Fisher Scientific (US), Illumina (US)
Segments CoveredApplication, Sample Type, Technology, End Use
Key Market OpportunitiesAdvancements in non-invasive cancer diagnostics drive growth in the liquid biopsy market.
Key Market DynamicsRising demand for non-invasive cancer diagnostics drives innovation and competition in the liquid biopsy market.
Countries CoveredSouth Korea

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FAQs

What is the projected market size of the South Korea Liquid Biopsy Market for the year 2024?

The South Korea Liquid Biopsy Market is expected to be valued at 182.0 million USD in 2024.

What is the expected compound annual growth rate (CAGR) for the South Korea Liquid Biopsy Market from 2025 to 2035?

The expected CAGR for the South Korea Liquid Biopsy Market from 2025 to 2035 is 10.503 percent.

How much will the South Korea Liquid Biopsy Market grow by 2035?

By 2035, the South Korea Liquid Biopsy Market is projected to reach a value of 546.0 million USD.

What are the values for Circulating Tumor Cells in the South Korea Liquid Biopsy Market for 2024?

Circulating Tumor Cells are valued at 50.0 million USD in the South Korea Liquid Biopsy Market in 2024.

What is the estimated value for Circulating Tumor DNA in the South Korea Liquid Biopsy Market for 2035?

By 2035, Circulating Tumor DNA is estimated to be valued at 210.0 million USD in the South Korea Liquid Biopsy Market.

Who are the key players in the South Korea Liquid Biopsy Market?

Key players in the South Korea Liquid Biopsy Market include companies such as Natera, Illumina, and Thermo Fisher Scientific.

What is the value of Extracellular Vesicles in the South Korea Liquid Biopsy Market for 2024?

Extracellular Vesicles are valued at 40.0 million USD in the South Korea Liquid Biopsy Market in 2024.

What growth opportunities exist in the South Korea Liquid Biopsy Market from 2025 to 2035?

The market presents growth opportunities driven by advancements in cancer detection and personalized medicine.

What challenges may impact the South Korea Liquid Biopsy Market during the forecast period?

Challenges might include regulatory hurdles and the need for robust clinical validation across various applications.

What is the projected value for 'Others' in the South Korea Liquid Biopsy Market for 2024?

'Others' in the South Korea Liquid Biopsy Market is projected to be valued at 22.0 million USD in 2024.

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