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    Retinitis Pigmentosa Treatment Market

    ID: MRFR/HC/36181-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Retinitis Pigmentosa Treatment Market Research Report By Treatment Type (Gene Therapy, Stem Cell Therapy, Optogenetics, Artificial Retinal Implants, Pharmaceutical Therapies), By Disease Severity (Early-Stage Retinitis Pigmentosa, Intermediate-Stage Retinitis Pigmentosa, Advanced-Stage Retinitis Pigmentosa), By Product (Luxturna, Zolgensma, Opsin Gene Therapy, Retina Implant Alpha AMS, Retina Implant Argus II), By Application (Inherited Retinal Degenerations, Age-Related Macular Degeneration, Diabetic Retinopathy, Glaucoma) and By Regional ...

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    Retinitis Pigmentosa Treatment Market Infographic

    Retinitis Pigmentosa Treatment Market Summary

    As per MRFR analysis, the Retinitis Pigmentosa Treatment Market Size was estimated at 3.053 USD Billion in 2024. The Retinitis Pigmentosa Treatment industry is projected to grow from 3.277 USD Billion in 2025 to 6.641 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 7.32 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Retinitis Pigmentosa Treatment Market is poised for substantial growth driven by innovative therapies and increasing patient awareness.

    • The emergence of gene therapy is transforming treatment options, establishing it as the largest segment in the market.
    • Advancements in retinal implants are enhancing patient outcomes, particularly in North America, the largest market for these technologies.
    • Personalized medicine is gaining traction, especially in the Asia-Pacific region, which is recognized as the fastest-growing market.
    • The increasing prevalence of Retinitis Pigmentosa and rising investment in ophthalmic research are key drivers propelling market expansion.

    Market Size & Forecast

    2024 Market Size 3.053 (USD Billion)
    2035 Market Size 6.641 (USD Billion)
    CAGR (2025 - 2035) 7.32%

    Major Players

    Novartis (CH), Roche (CH), Regeneron Pharmaceuticals (US), Santen Pharmaceutical (JP), Spark Therapeutics (US), Astellas Pharma (JP), GenSight Biologics (FR), Bayer (DE), Alkeus Pharmaceuticals (US)

    Retinitis Pigmentosa Treatment Market Trends

    The Retinitis Pigmentosa Treatment Market is currently experiencing a dynamic evolution, driven by advancements in therapeutic approaches and a growing understanding of the underlying genetic factors associated with the condition. Innovative treatment modalities, including gene therapy and retinal implants, are emerging as potential solutions, offering hope to patients affected by this degenerative eye disease. The increasing prevalence of Retinitis Pigmentosa, coupled with heightened awareness among healthcare professionals and patients, is likely to propel the demand for effective treatment options. Furthermore, ongoing research initiatives and collaborations among pharmaceutical companies, academic institutions, and healthcare providers are fostering an environment conducive to the development of novel therapies. In addition, the Retinitis Pigmentosa Treatment Market appears to be influenced by the rising trend of personalized medicine, which emphasizes tailored treatment strategies based on individual genetic profiles. This shift towards precision medicine may enhance treatment efficacy and improve patient outcomes. As the market continues to evolve, it is essential to monitor regulatory developments and reimbursement policies that could impact the accessibility and affordability of emerging therapies. Overall, the Retinitis Pigmentosa Treatment Market is poised for growth, driven by innovation, collaboration, and a commitment to improving the quality of life for individuals affected by this condition.

    Emergence of Gene Therapy

    Gene therapy is gaining traction as a promising approach in the Retinitis Pigmentosa Treatment Market. This innovative technique aims to address the root cause of the disease by correcting genetic defects. As research progresses, the potential for gene therapy to restore vision or halt disease progression appears increasingly viable.

    Advancements in Retinal Implants

    Retinal implants are becoming a focal point in the Retinitis Pigmentosa Treatment Market. These devices aim to replace damaged photoreceptors, offering a new avenue for vision restoration. The ongoing refinement of implant technology suggests a future where more patients may benefit from these interventions.

    Focus on Personalized Medicine

    The trend towards personalized medicine is reshaping the Retinitis Pigmentosa Treatment Market. Tailoring treatments to individual genetic profiles may enhance therapeutic effectiveness. This approach indicates a shift in how therapies are developed and administered, potentially leading to improved patient outcomes.

    The ongoing advancements in gene therapy and innovative drug development appear to be reshaping the landscape of treatment options for Retinitis Pigmentosa, potentially offering new hope for patients worldwide.

    National Eye Institute, National Institutes of Health

    Retinitis Pigmentosa Treatment Market Drivers

    Growing Investment in Ophthalmic Research

    The Retinitis Pigmentosa Treatment Market is experiencing a surge in investment directed towards ophthalmic research. Increased funding from both public and private sectors is facilitating the exploration of new treatment avenues. For example, government grants and initiatives aimed at combating visual impairments are becoming more prevalent, thereby supporting research into RP therapies. This financial backing is crucial for advancing clinical trials and bringing innovative treatments to market. Furthermore, collaborations between academic institutions and pharmaceutical companies are likely to enhance the development pipeline, leading to a more diverse range of treatment options for patients suffering from Retinitis Pigmentosa.

    Regulatory Support for Innovative Therapies

    Regulatory bodies are increasingly providing support for the development of innovative therapies within the Retinitis Pigmentosa Treatment Market. Initiatives aimed at expediting the approval process for breakthrough treatments are becoming more common. This regulatory environment encourages pharmaceutical companies to invest in research and development, knowing that their innovative solutions may receive faster market access. The potential for accelerated approval pathways for gene therapies and other novel treatments is likely to enhance the attractiveness of the RP treatment market. As a result, this supportive regulatory landscape may lead to a more rapid introduction of effective therapies, ultimately benefiting patients.

    Rising Awareness and Advocacy for Eye Health

    The growing awareness surrounding eye health and conditions like Retinitis Pigmentosa is a significant driver for the Retinitis Pigmentosa Treatment Market. Advocacy groups and organizations are actively working to educate the public about RP, its symptoms, and available treatment options. This heightened awareness is likely to lead to earlier diagnoses and increased patient engagement in treatment decisions. As more individuals become informed about their options, the demand for effective therapies is expected to rise. Additionally, awareness campaigns can influence policy changes and funding allocations, further supporting research and development efforts in the field of RP treatment.

    Increasing Prevalence of Retinitis Pigmentosa

    The rising incidence of Retinitis Pigmentosa (RP) is a crucial driver for the Retinitis Pigmentosa Treatment Market. It is estimated that RP affects approximately 1 in 4,000 individuals, leading to a growing patient population in need of effective treatments. As awareness of the condition increases, more individuals are being diagnosed, which in turn fuels demand for innovative therapies. The increasing prevalence is likely to stimulate research and development efforts, as pharmaceutical companies and research institutions seek to address the unmet needs of patients. This trend suggests a robust market potential, as stakeholders aim to develop and commercialize new treatment options that can improve the quality of life for those affected by RP.

    Technological Advancements in Treatment Modalities

    Technological innovations are significantly shaping the Retinitis Pigmentosa Treatment Market. Recent advancements in gene therapy, retinal implants, and other therapeutic modalities are paving the way for novel treatment options. For instance, gene therapy approaches have shown promise in clinical trials, potentially offering long-term solutions for patients. The market is witnessing an influx of new technologies that aim to restore vision or slow disease progression. This influx of innovation not only enhances treatment efficacy but also attracts investment from various stakeholders, including venture capitalists and pharmaceutical companies. As these technologies continue to evolve, they are expected to play a pivotal role in expanding the treatment landscape for Retinitis Pigmentosa.

    Market Segment Insights

    By Type: Gene Therapy (Largest) vs. Stem Cell Therapy (Fastest-Growing)

    In the Retinitis Pigmentosa Treatment Market, Gene Therapy holds the largest market share, significantly surpassing other treatment options. With advancements in genetics and a growing acceptance of such therapies among patients and healthcare providers, Gene Therapy stands out as the leading approach. Stem Cell Therapy, while currently smaller in market share, is gaining traction due to its innovative potential and ongoing research efforts.

    Treatment Methods: Gene Therapy (Dominant) vs. Stem Cell Therapy (Emerging)

    Gene Therapy is currently the dominant treatment method in the Retinitis Pigmentosa landscape, focusing on correcting genetic defects that lead to the disease. Its ability to offer potentially long-lasting solutions appeals to many patients. In contrast, Stem Cell Therapy is an emerging method that shows promise for regenerating retinal cells and restoring vision. Ongoing clinical trials highlight its potential benefits, driving interest and investment in this area. The dynamic nature of these segments reflects a shift towards personalized medicine and innovative treatment options, attracting attention from both patients and developers.

    By Disease Severity: Intermediate-Stage Retinitis Pigmentosa (Largest) vs. Advanced-Stage Retinitis Pigmentosa (Fastest-Growing)

    The Retinitis Pigmentosa Treatment Market exhibits varied revenue potential across its disease severity segments. The largest share belongs to the Intermediate-Stage Retinitis Pigmentosa, as it attracts more treatment modalities and patient enrollments due to increasing diagnosis rates. In contrast, the Advanced-Stage segment, while currently smaller, is rapidly gaining attention with innovative therapies targeting end-stage patients becoming more prevalent, thus contributing to its agile growth in the marketplace. Growth trends in the Retinitis Pigmentosa Treatment Market reveal that the Intermediate-Stage segment benefits from a robust pipeline of therapeutics, positioning it as the preferred choice among healthcare providers. However, the Advanced-Stage segment is poised for significant expansion as new technologies and patient-centric solutions emerge. The combination of increasing awareness, healthcare investments, and advancements in gene therapies offers promising prospects for both segments, yet the Advanced-Stage segment stands out as the fastest growing, driven by rising demand for comprehensive treatment solutions.

    Intermediate-Stage Retinitis Pigmentosa (Dominant) vs. Advanced-Stage Retinitis Pigmentosa (Emerging)

    Intermediate-Stage Retinitis Pigmentosa is currently the dominant segment in the market, characterized by a progressive deterioration of vision that still allows for several effective treatment options. This stage witnesses considerable interest from pharmaceutical companies, resulting in a rich pipeline of potential therapies aimed at halting progression and improving patient quality of life. In contrast, the Advanced-Stage Retinitis Pigmentosa represents an emerging segment, featuring patients who have experienced significant vision loss and are often facing limited options. The growing need for advanced interventions like gene therapy and retinal implants highlights its emergence, with research focusing on rehabilitation and innovative treatment solutions tailored to enhance the remaining vision. As the healthcare landscape evolves, both segments will play crucial roles in shaping the Retinitis Pigmentosa treatment paradigm.

    By Product: Luxturna (Largest) vs. Zolgensma (Fastest-Growing)

    The 'Product' segment in the Retinitis Pigmentosa Treatment Market showcases a competitive landscape with key players like Luxturna, Zolgensma, Opsin Gene Therapy, Retina Implant Alpha AMS, and Retina Implant Argus II. Luxturna leads the market due to its established presence and favorable outcomes, capturing the largest share in the segment. Zolgensma, while not the largest, is identified as the fastest-growing product due to its innovative approach and significant clinical trial results. Other therapies like Opsin Gene Therapy and Retina Implants are gaining traction, contributing to a diverse treatment ecosystem.

    Luxturna: Dominant vs. Zolgensma: Emerging

    Luxturna, as a dominant player, has been pivotal in transforming the treatment landscape for Retinitis Pigmentosa with its gene therapy capabilities. It offers the first FDA-approved gene therapy for this condition, providing a substantial improvement in vision-related outcomes for patients. On the other hand, Zolgensma, known for its rapid growth, is paving the way for potential breakthroughs in gene therapy applications beyond its current indications, positioning itself as a key alternative for patients. Both products represent significant advancements in the field, but they serve different patient needs and stages of the disease, underpinning the nuanced dynamics of the market.

    By Application: Inherited Retinal Degenerations (Largest) vs. Age-Related Macular Degeneration (Fastest-Growing)

    In the Retinitis Pigmentosa Treatment Market, the application segment is prominently defined by four major categories: Inherited Retinal Degenerations, Age-Related Macular Degeneration, Diabetic Retinopathy, and Glaucoma. Among these, Inherited Retinal Degenerations holds the largest market share, reflecting a significant patient population and a long history of treatment options. Conversely, Age-Related Macular Degeneration is rapidly emerging as the fastest-growing segment, indicating a rising prevalence due to aging populations and increasing awareness of eye health.

    Inherited Retinal Degenerations (Dominant) vs. Age-Related Macular Degeneration (Emerging)

    Inherited Retinal Degenerations represents a dominant category within the Retinitis Pigmentosa Treatment Market, characterized by various genetic forms that lead to progressive blindness. This segment benefits from established treatment protocols and strong advocacy efforts focused on genetic research. In contrast, Age-Related Macular Degeneration is an emerging segment driven by the growing number of older adults and advancements in treatment technologies. The segment is witnessing robust growth due to innovation in therapeutic approaches, aimed at halting vision loss, making it a focal point for research and development. Overall, both segments underscore the importance of targeted therapies in managing retinal disorders.

    Get more detailed insights about Retinitis Pigmentosa Treatment Market

    Regional Insights

    North America : Leading Market for Innovation

    North America is the largest market for Retinitis Pigmentosa treatment, accounting for approximately 45% of the global market share. The region benefits from advanced healthcare infrastructure, significant R&D investments, and a growing prevalence of retinal diseases. Regulatory support from agencies like the FDA accelerates the approval of innovative therapies, driving market growth. The increasing awareness of genetic disorders and the demand for effective treatments further fuel this expansion. The United States is the primary contributor, with key players such as Regeneron Pharmaceuticals and Spark Therapeutics leading the charge. Canada also plays a significant role, focusing on research and development initiatives. The competitive landscape is characterized by collaborations between biotech firms and academic institutions, enhancing the pipeline of novel therapies. The presence of major pharmaceutical companies ensures a robust market environment, fostering innovation and accessibility.

    Europe : Emerging Market with Potential

    Europe is an emerging powerhouse in the Retinitis Pigmentosa treatment market, holding approximately 30% of the global share. The region is witnessing a surge in demand for innovative therapies, driven by increasing awareness and supportive regulatory frameworks. The European Medicines Agency (EMA) plays a crucial role in facilitating the approval of new treatments, which is vital for market growth. Additionally, the rising prevalence of retinal diseases among the aging population is a significant driver of demand. Leading countries such as Germany, France, and the UK are at the forefront of this market, with a strong presence of key players like Bayer and GenSight Biologics. The competitive landscape is marked by strategic partnerships and collaborations aimed at enhancing research and development. The focus on personalized medicine and gene therapies is expected to shape the future of the market, providing new avenues for treatment and improving patient outcomes.

    Asia-Pacific : Rapidly Growing Market

    Asia-Pacific is rapidly emerging as a significant market for Retinitis Pigmentosa treatment, accounting for about 20% of the global market share. The region's growth is driven by increasing healthcare expenditure, rising awareness of genetic disorders, and a growing patient population. Countries like Japan and China are leading this expansion, supported by favorable government initiatives and investments in healthcare infrastructure. The regulatory environment is becoming more conducive to the approval of new therapies, further propelling market growth. Japan is a key player in the market, with companies like Santen Pharmaceutical and Astellas Pharma actively involved in developing innovative treatments. China is also witnessing a surge in research activities and collaborations with international firms. The competitive landscape is characterized by a mix of local and global players, focusing on enhancing treatment options and improving patient access to therapies. The emphasis on research and development is expected to drive future growth in this region.

    Middle East and Africa : Untapped Market Potential

    The Middle East and Africa represent an untapped frontier in the Retinitis Pigmentosa treatment market, holding approximately 5% of the global share. The region faces challenges such as limited healthcare infrastructure and awareness, but there is a growing recognition of the need for effective treatments. Government initiatives aimed at improving healthcare access and increasing funding for rare diseases are expected to catalyze market growth. The rising prevalence of retinal diseases is also driving demand for innovative therapies. Countries like South Africa and the UAE are beginning to invest in research and development, with a focus on improving treatment options for retinal disorders. The competitive landscape is still developing, with a few local players and international companies exploring opportunities in the region. Collaborations between governments and healthcare organizations are essential to enhance treatment accessibility and improve patient outcomes, paving the way for future growth in this market.

    Key Players and Competitive Insights

    The Retinitis Pigmentosa Treatment Market is characterized by a dynamic competitive landscape, driven by a confluence of innovation, strategic partnerships, and a growing emphasis on personalized medicine. Key players such as Novartis (CH), Regeneron Pharmaceuticals (US), and Spark Therapeutics (US) are at the forefront, each adopting distinct strategies to enhance their market positioning. Novartis (CH) has focused on expanding its research capabilities, particularly in gene therapy, which aligns with the increasing demand for targeted treatments. Meanwhile, Regeneron Pharmaceuticals (US) has been leveraging its robust pipeline of biologics, indicating a commitment to innovation in therapeutic solutions. Spark Therapeutics (US), known for its pioneering work in gene therapy, continues to solidify its market presence through strategic collaborations aimed at accelerating product development and enhancing patient access.

    In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The competitive structure of the Retinitis Pigmentosa Treatment Market appears moderately fragmented, with several players vying for market share. This fragmentation is indicative of a landscape where innovation and strategic partnerships play a crucial role in shaping competitive dynamics, as companies seek to differentiate themselves through unique offerings and enhanced service delivery.

    In August 2025, Novartis (CH) announced a strategic partnership with a leading biotechnology firm to co-develop a novel gene therapy aimed at treating Retinitis Pigmentosa. This collaboration is expected to leverage both companies' expertise in genetic research, potentially accelerating the development timeline and enhancing the therapeutic options available to patients. Such partnerships not only bolster Novartis's research capabilities but also signify a broader trend towards collaborative innovation in the industry.

    In September 2025, Regeneron Pharmaceuticals (US) unveiled a new clinical trial for its innovative biologic treatment targeting Retinitis Pigmentosa. This trial aims to assess the efficacy of a dual-action therapy that combines gene editing with traditional pharmacological approaches. The strategic importance of this initiative lies in its potential to redefine treatment paradigms, offering a more comprehensive approach to managing the disease and addressing unmet medical needs.

    In July 2025, Spark Therapeutics (US) launched a patient assistance program designed to improve access to its gene therapy for Retinitis Pigmentosa. This initiative reflects a growing recognition of the importance of patient-centric strategies in the pharmaceutical industry. By enhancing accessibility, Spark Therapeutics not only strengthens its market position but also aligns with the increasing emphasis on health equity and patient engagement in treatment decisions.

    As of October 2025, the competitive trends in the Retinitis Pigmentosa Treatment Market are increasingly influenced by digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are becoming more prevalent, as companies recognize the value of collaborative efforts in navigating complex regulatory environments and accelerating innovation. Looking ahead, competitive differentiation is likely to evolve from traditional price-based strategies to a focus on technological advancements, innovative treatment modalities, and reliable supply chains, underscoring the industry's shift towards a more sustainable and patient-focused future.

    Key Companies in the Retinitis Pigmentosa Treatment Market market include

    Industry Developments

    • Q2 2024: Ocugen Announces FDA Approval of IND Amendment to Initiate Phase III Clinical Trial of OCU400 for Retinitis Pigmentosa In April 2024, Ocugen received FDA approval for its Investigational New Drug (IND) amendment, allowing the company to begin a Phase III clinical trial of OCU400, a gene therapy candidate for retinitis pigmentosa.
    • Q2 2024: ViGeneron Announces First Patient Dosed in Phase Ib Clinical Trial of VG901 for Retinitis Pigmentosa In April 2024, ViGeneron announced that the first patient had been dosed in its Phase Ib clinical trial evaluating VG901, an intravitreal gene therapy for retinitis pigmentosa caused by CNGA1 gene mutations.
    • Q1 2024: Nanoscope Therapeutics Reports Positive Top-Line Results from Phase IIb RESTORE Trial of MCO-010 for Retinitis Pigmentosa In March 2024, Nanoscope Therapeutics announced positive top-line results from its completed 2-year Phase IIb RESTORE trial of MCO-010, a mutation-agnostic gene therapy for advanced retinitis pigmentosa.

    Future Outlook

    Retinitis Pigmentosa Treatment Market Future Outlook

    The Retinitis Pigmentosa Treatment Market is projected to grow at a 7.32% CAGR from 2024 to 2035, driven by advancements in gene therapy, increased awareness, and rising healthcare investments.

    New opportunities lie in:

    • Development of personalized gene therapies targeting specific genetic mutations.
    • Expansion of telemedicine platforms for remote patient monitoring and consultations.
    • Investment in AI-driven diagnostic tools for early detection and treatment planning.

    By 2035, the Retinitis Pigmentosa Treatment Market is expected to achieve substantial growth and innovation.

    Market Segmentation

    Retinitis Pigmentosa Treatment Market Type Outlook

    • Gene Therapy
    • Stem Cell Therapy
    • Optogenetics
    • Artificial Retinal Implants
    • Pharmaceutical Therapies

    Retinitis Pigmentosa Treatment Market Product Outlook

    • Luxturna
    • Zolgensma
    • Opsin Gene Therapy
    • Retina Implant Alpha AMS
    • Retina Implant Argus II

    Retinitis Pigmentosa Treatment Market Application Outlook

    • Inherited Retinal Degenerations
    • Age-Related Macular Degeneration
    • Diabetic Retinopathy
    • Glaucoma

    Retinitis Pigmentosa Treatment Market Disease Severity Outlook

    • Early-Stage Retinitis Pigmentosa
    • Intermediate-Stage Retinitis Pigmentosa
    • Advanced-Stage Retinitis Pigmentosa

    Report Scope

    MARKET SIZE 20243.053(USD Billion)
    MARKET SIZE 20253.277(USD Billion)
    MARKET SIZE 20356.641(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)7.32% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesAdvancements in gene therapy and retinal implants drive growth in the Retinitis Pigmentosa Treatment Market.
    Key Market DynamicsRising demand for innovative therapies drives competition and investment in Retinitis Pigmentosa treatment advancements.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

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    FAQs

    What is the projected market valuation for the Retinitis Pigmentosa Treatment Market in 2035?

    The projected market valuation for the Retinitis Pigmentosa Treatment Market in 2035 is 6.641 USD Billion.

    What was the market valuation for the Retinitis Pigmentosa Treatment Market in 2024?

    The market valuation for the Retinitis Pigmentosa Treatment Market in 2024 was 3.053 USD Billion.

    What is the expected CAGR for the Retinitis Pigmentosa Treatment Market from 2025 to 2035?

    The expected CAGR for the Retinitis Pigmentosa Treatment Market during the forecast period 2025 - 2035 is 7.32%.

    Which companies are key players in the Retinitis Pigmentosa Treatment Market?

    Key players in the Retinitis Pigmentosa Treatment Market include Novartis, Roche, Regeneron Pharmaceuticals, and others.

    What are the main segments of the Retinitis Pigmentosa Treatment Market?

    The main segments of the Retinitis Pigmentosa Treatment Market include Gene Therapy, Stem Cell Therapy, and Pharmaceutical Therapies.

    How much is the Gene Therapy segment projected to be valued by 2035?

    The Gene Therapy segment is projected to be valued between 1.2 and 1.5 USD Billion by 2035.

    What is the valuation range for Pharmaceutical Therapies in 2035?

    The valuation range for Pharmaceutical Therapies in 2035 is expected to be between 3.341 and 4.000 USD Billion.

    What is the expected market size for Advanced-Stage Retinitis Pigmentosa by 2035?

    The expected market size for Advanced-Stage Retinitis Pigmentosa by 2035 is projected to be between 1.991 and 2.500 USD Billion.

    Which product is anticipated to have the highest valuation in the Retinitis Pigmentosa Treatment Market?

    Luxturna is anticipated to have the highest valuation, projected between 1.2 and 1.5 USD Billion by 2035.

    What applications are driving growth in the Retinitis Pigmentosa Treatment Market?

    Applications such as Inherited Retinal Degenerations and Age-Related Macular Degeneration are driving growth in the market.

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