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Ion Chromatography Market Research Report: Information By Technique (lon-exchange Chromatography, lon-exclusion Chromatography, and lon-pair Chromatography), By Application (Environmental Testing, Pharmaceutical Industry, Food Industry, Chemical Industry), and By Region (North America, Europe, Asia-Pacific, and Rest Of The World) – Market Forecast Till 2032


ID: MRFR/HC/9305-HCR | 120 Pages | Author: Rahul Gotadki| June 2024

Global Ion Chromatography Market Overview


Ion Chromatography Market Size was valued at USD 2.3 Billion in 2023. The Ion Chromatography market Technique is projected to grow from USD 2.49 Billion in 2024 to USD 4.4 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.35% during the forecast period (2024 - 2032).Ion chromatography is in greater demand as a result of increased drug analysis and food safety concerns in the pharmaceutical sector, are the key market drivers enhancing the market growth. 


Ion Chromatography Market1


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Ion Chromatography Market Trends



  • Rising demand for ion chromatography in the pharmaceutical industry and drug analysis is driving the market growth


An established and well-liked method for measuring and analysing charged species is lon chromatography. The pharmaceutical industry, among others, has benefited from the development and maturation of ion chromatography (IC), which has become a significant analytical methodology. However, the most popular chromatographic technique for analysing pharmaceuticals in the pharmaceutical industry is reversed-phase chromatography. IC is a substitute technique for ionic species that is frequently used to validate drug analysis, especially sulfa drug analysis. To identify counterions and excipients in "off-the-shelf" medications, the pharmaceutical industry uses ion exchange and ion exclusion chromatography. In accordance with regulatory standards like the European Pharmacopoeia and US Pharmacopoeia laws, medications including gentamicin, neomycin, bethanechol chloride, and cefadroxil contain Active Pharmaceutical Ingredients (APIs) that can be identified using the IC technique. The popularity of IC approaches for drug determination is increasing, and these regulatory criteria are fueling this rise.


The ion chromatography market is expanding as a result of rising academic and commercial R&D expenditures on pharmaceutical research and development, technological developments, and growing use of ion-exchange techniques in the food, beverage, and water sectors. to verify things like quality, safety, or content. Using the ion-exchange method, it is also possible to determine whether or how many components are present in a sample. Furthermore, ion-exchange chromatography (IEX) is used in non-aqueous mobile phases to purify a non-crystalline intermediate after a reductive amination with D-xylose with strength and purity of the intermediate allowing successful downstream processing, according to the study titled "Non-aqueous Ion-Exchange Chromatography Using High Acid-base Concentration: A Strategy for Purifying Non-crystalline Pharmaceutical Intermediates" in March 2021. Due to the high use of this method in the pharmaceutical industry, the importance of ion chromatography in pharmaceutical production is therefore anticipated to drive market expansion.


The rising demand for monoclonal antibodies, a key market driver, combined with the growing use of ion-exchange chromatography for purification are the two factors contributing to the expansion of the worldwide ion chromatography market. Additionally, the National Institutes of Health (NIH) received USD 700 billion in federal funding over the previous 20 years, according to the Congressional Budget Office in April 2021. Such funding has supported fundamental Molecular biology, genetics, and other life sciences research has helped to identify new disease pathways. Real annual budget increases helped the NIH reach USD 41 billion in 2020. Therefore, the adoption of ion chromatography in R&D will result from the increased funding for research and development in basic research, spurring market expansion. Thus, driving the Ion Chromatography market revenue.


Ion Chromatography Market Segment Insights


Ion Chromatography Technique Insights


The Ion Chromatography market segmentation, based on technique, includes lon-exchange chromatography, lon-exclusion chromatography, and lon-pair chromatography. Ion-exclusion chromatography segment dominated the market in 2022. The rising use of ion-exchange techniques in the water sector and the food & beverage industry can be linked to the market expansion for the ion-exchange chromatography segment. In numerous environmental testing businesses, the approach is also utilised to evaluate the quality, substance, and safety of the products. The method is also employed to determine whether or not a sample contains any components. As a result, the aforementioned elements are promoting market expansion.


Ion Chromatography Application Insights


The Ion Chromatography market segmentation, based on application, includes environmental testing, pharmaceutical industry, food industry, chemical industry. Pharmaceutical industry segment dominated the Ion Chromatography market in 2022.A few of the main elements influencing the segment's growth are the availability of government and corporate financing for biotechnology and pharmaceutical research as well as the quickly expanding pharmaceutical sector. Additionally, rising R&D efforts in this sector for diseases including cancer and HIV/AIDS, as well as pharmaceutical and biotechnology companies' increased emphasis on building out their product pipelines, are some of the key drivers of market expansion.


Figure 1: Ion Chromatography Market, by Application, 2022 & 2032 (USD Billion) 


Ion Chromatography Market, by Application, 2022 & 2032


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Ion Chromatography Regional Insights


By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North America Ion Chromatography Market dominated this market in 2022 (45.80%). This expansion is linked to the presence of ongoing technological advancements, which led to discoveries that encouraged the leading businesses in this sector to implement novel ion separation techniques. These participants take part in the introduction of new products, purchases, growth, and strategic alliances. For instance, the biopharma division of General Electric Life Sciences (US), now known as Cytiva, was purchased by Danaher Corporation (US) in March 2020 for USD 21.4 billion. The company's standing in the life sciences market has improved as a result of this action. Further, the U.S. Ion Chromatography market held the largest market share, and the Canada Ion Chromatography market was the fastest growing market in the North America region.


Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2: ION CHROMATOGRAPHY MARKET SHARE BY REGION 2022 (USD Billion) 


ION CHROMATOGRAPHY MARKET SHARE BY REGION 2022


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe Ion Chromatography market accounted for the healthy market share in 2022. The adoption of Using high-performance liquid chromatography (HPLC) for factory testing and quality control in the pharmaceutical and food & beverage industries, as well as rising R&D spending, are what are driving the European ion chromatography market. These factors are also boosting the popularity of LC-MS (Liquid Chromatography-Mass Spectrometry).Further, the German Ion Chromatography market held the largest market share, and the U.K Ion Chromatography market was the fastest growing market in the European region.


The Asia Pacific Ion Chromatography market is expected to register significant growth from 2023 to 2032. This is because of things like expanding healthcare infrastructure, increased demand for ion chromatography in fields like forensics, pharmaceuticals, and environmental testing, and advancements in techniques that make using chromatography processes more practical and available. Moreover, China’s Ion Chromatography market held the largest market share, and the Indian Ion Chromatography market was the fastest growing market in the Asia-Pacific region.


Ion Chromatography Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development in order to expand their product lines, which will help the Ion Chromatography market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Ion Chromatography Industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the Ion Chromatography Industry to benefit clients and increase the market sector. In recent years, the Ion Chromatography Industry has offered some of the most significant advantages to medicine. Major players in the Ion Chromatography market, including Thermo Fisher Scientific, Metrohm, Tosoh Bioscience, Shimadzu, Qingdao Shenghan Chromatograph Technology Co., Ltd, MembraPure GmbH, Nittoseiko Analytech Co., Ltd, Qingdao Puren Instrument, East & West Analytical Instruments, Qingdao Luhai, Sykam, and Cecil Instruments, are attempting to increase market demand by investing in research and development operations.


Thermo Fisher Scientific Inc. (Thermo Fisher) delivers medical devices, analytical instruments, reagents and consumables, software, and services to address the demands of challenging analytical challenges in research, diagnostics, and clinical laboratories. It provides answers for flow cytometry, synthetic biology, and cellular biology. The business offers a variety of goods, such as mass spectrometry, genetic sequencing, electron microscopy, protein, and molecular biology research technology. The company offers services to companies in the environmental, industrial quality, and process control sectors, as well as to academic and research institutes, governmental organisations, pharmaceutical and biotech companies, clinical diagnostic laboratories, and environmental companies. In the Americas, Asia-Pacific, and Europe, it sells its goods and services through its direct sales force, online sales, and third-party distributors. Waltham, Massachusetts, in the United States, is home to Thermo Fisher. To promote quantitative analysis, Thermo Fisher Scientific (US) unveiled a new Mass Spectrometry (MS) range in September 2021. The company's combination with software and systems for liquid and ion chromatography produces reliable quantitative application solutions.


For use in life science research, healthcare, analytical chemistry, and other markets, Bio-Rad Laboratories Inc (Bio-Rad) develops, produces, and markets a variety of products and systems. Reagents, apparatus, laboratory equipment, test systems, informatics systems, test kits, and specialised quality controls are among the company's main offerings. Universities and medical schools, industrial research organisations, pharmaceutical companies, governmental organisations, biotechnology researchers, food producers, food testing laboratories, reference laboratories, hospital and transfusion laboratories, and doctor's offices are just a few of the organisations that can use Bio-Rad's products. Products are marketed directly to consumers as well as through a network of distributors, agents, brokers, and resellers. Among other places, the company conducts business in the US, Canada, Latin America, Europe, and Asia. The U.S. city of Hercules, California, is where Bio-Rad is based. EconoFit Chromatography Column packs, which include mixed-mode, cation, and anion exchange resin columns in a prepacked style, as well as a pack tailored for polyhistidine protein purification, were introduced by Bio-Rad in June 2022.


Key Companies in the Ion Chromatography market include




  • Thermo Fisher Scientific




  • Metrohm




  • Tosoh Bioscience




  • Shimadzu




  • Qingdao Shenghan Chromatograph Technology Co., Ltd




  • MembraPure GmbH




  • Nittoseiko Analytech Co., Ltd




  • Qingdao Puren Instrument




  • East & West Analytical Instruments




  • Qingdao Luhai




  • Sykam




  • Cecil Instruments




Ion Chromatography Industry Developments


January 2021: A collaborative agreement was reached regarding the proposed sale of Novasep's chromatography equipment division. Sartorius Stedim Biotech is a division of the German life science firm Sartorius and is a leading provider of services and technologies for the life sciences sector.


May 2022: To safeguard the food supply, Thermofisher introduced quat pesticide determination and quantification procedures. It allows researchers to quickly and precisely identify and quantify cationic insecticides.


Ion Chromatography Market Segmentation


Ion Chromatography Technique Outlook




  • lon-exchange Chromatography




  • lon-exclusion Chromatography




  • lon-pair Chromatography




Ion Chromatography Application Outlook




  • Environmental Testing




  • Pharmaceutical Industry




  • Food Industry




  • Chemical Industry




 Ion Chromatography Regional Outlook




  • North America







    • US

    • Canada






  • Europe







    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe






  • Asia-Pacific




    • China




    • Japan




    • India




    • Australia




    • South Korea




    • Australia




    • Rest of Asia-Pacific






  • Rest of the World




    • Middle East




    • Africa




    • Latin America





Report Attribute/Metric Details
Market Size 2023 USD 2.3 Billion
Market Size 2024 USD 2.49 Billion
Market Size 2032 USD 4.4 Billion
Compound Annual Growth Rate (CAGR) 7.35% (2024-2032)
Base Year 2023
Market Forecast Period 2024-2032
Historical Data 2018- 2022
Market Forecast Units Value (USD Billion)
Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered Technique, Application, and Region
Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
Countries Covered The U.S., Canada, German, France, U.K, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled Thermo Fisher Scientific, Metrohm, Tosoh Bioscience, Shimadzu, Qingdao Shenghan Chromatograph Technology Co., Ltd, MembraPure GmbH, Nittoseiko Analytech Co., Ltd, Qingdao Puren Instrument, East & West Analytical Instruments, Qingdao Luhai, Sykam, and Cecil Instruments
Key Market Opportunities Increasing use of chromatography in the purification of monoclonal antibodies
Key Market Dynamics Rising demand for ion chromatography in the pharmaceutical industry and drug analysis and growing food safety concerns


Frequently Asked Questions (FAQ) :

The Ion Chromatography market size was valued at USD 2.3 Billion in 2023.

The market is projected to grow at a CAGR of 7.35% during the forecast period, 2024-2032.

North America had the largest share in the market

The key players in the market are Thermo Fisher Scientific, Metrohm, Tosoh Bioscience, Shimadzu, Qingdao Shenghan Chromatograph Technology Co., Ltd, MembraPure GmbH, Nittoseiko Analytech Co., Ltd, Qingdao Puren Instrument, East & West Analytical Instruments, Qingdao Luhai, Sykam, and Cecil Instruments

The lon-exchange Chromatography Technique dominated the market in 2023.

The Pharmaceutical Industry Application had the largest share in the market.

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