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Competent Cells Market Research Report Information By Type (Chemically Competent Cells And Electrocompetent Cells), By Application (Cloning, Protein Expression, And Other), By End-User (Pharmaceutical And Biotechnology Companies, Academic Research Institutes, And Others), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2032


ID: MRFR/HC/10091-HCR | 128 Pages | Author: Rahul Gotadki| July 2024

Global Competent Cells Market Overview


Competent Cells Market Size was valued at USD 1.9 Billion in 2022 and is projected to grow from USD 2.1 Billion in 2023 to USD 4.8 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 10.90% during the forecast period (2023 - 2032). Research on molecular cloning has advanced as a result of new technological developments and rising consumer and business demand for recombinant proteins and molecularly cloned goods., are the key market drivers enhancing the market growth.


Competent Cells Market Overview


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Competent Cells Market Trends


The increasing demand for recombinant DNA technique products is driving the market growth


Recombinant DND procedures have a wide range of uses, including gene therapy, the creation of vaccines, the treatment of cancer, and the management of retroviruses. The development of molecular engineering and expanding scientific understanding of therapeutic items used to cure a variety of disorders are projected to increase consumer demand. An increase in governmental expenditure in research activities as well as the profitable expansion of developing nations will also contribute to the growth of lucrative chances for participants in the cell industry.


The possibility for various biotechnology and genetic engineering companies to provide cutting-edge remedies for a range of diseases that were previously impractical due to the spread of medical care is anticipated to fuel market growth. The government's increasing investment in research programs, successful pharmaceutical drug development research, and a supportive regulatory and reimbursement framework are all predicted to have a positive impact on the business. Additionally, governments in the majority of nations have increased their focus on modernizing healthcare infrastructure and developing treatments for particular ailments as disease rates rise. They have therefore increased their investment in biotechnology companies and streamlined rules to promote the development of treatments for critical ailments.


In the near future, market growth is anticipated to be boosted by increased investment in DNA cloning technologies investigations in academic research centers and applying these products in medicines. Demand growth is also anticipated to be fueled by rising government and industry investments as well as the introduction of new product categories. Thus, driving the Competent Cells market revenue.


Competent Cells Market Segment Insights


Competent Cells Type Insights


The Market segments of Competent Cells, based on Type includes chemically competent cells and electrocompetent cells. The segment of chemically competent cells is anticipated to hold the biggest market share for competent cells worldwide. Chemically competent cells are treated with calcium chloride and alternately heated in a water bath or under heat shock to open pores for plasmid allowance to enter the cell membrane. This helps the binding of plasmid DNA to the competent cell membrane. The finest option for cloning and subcloning applications is provided by these.


Competent Cells Application Insights


The Competent Cells Market segmentation, based on Application, includes cloning, protein expression, and other. Since it creates medicines, vaccines, and proteins using DNA copies of cells, organs, or even whole animals, the cloning segment dominates the market for competent cells. Transgenic animals, pest-resistant plants, and gene therapy are other uses for it. DNA cloning, in which the bacteria absorb the genetic material, uses bacterial transformation. Applications involving molecular biology frequently use this technique. Because of the government's increasing investment and assistance, this sector has expanded.


Competent Cells End-User Insights


The Market segmentation of Competent Cells, based on End User, pharmaceutical and biotechnology companies, academic research institutes, and others. Academic research institutes are anticipated to hold the biggest market share due to rising research expenditures in biotechnological applications. But during the projected period, the pharmaceutical and biotechnology firms section is anticipated to grow the most. This is because pharmaceutical businesses are expected to assist augmented manufacturing, such as tailored medication, localized 3D printing of therapies, etc., by making contributions to intelligent automation technologies. The expansion of this market is also being fueled by the increasing research expenditures for the creation of goods based on proteomics and genomics.


Figure 1: Competent Cells Market, by End User, 2022 & 2032 (USD Billion)


Competent Cells Market by End User


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Competent Cells Regional Insights


By Region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. During the projected period, it is anticipated that the North America Competent Cells market would account for a large portion of the worldwide market of competent cells. The development is due to in-depth study on DNA cloning technologies, rising biotechnology research, high regional R&D spending, and the presence of major market competitors. For instance, according to an article from the NIH from March 2022, funding for biotechnology research in the United States was $7,847 million in 2021 and is projected to rise to $8,104 million by 2030. Similar to this, data from the Canadian government released in 2022 stated that over USD 500 million was committed over a four-year period, beginning in 2021–2022, to support the bioscience infrastructure in Canada. It is also anticipated that these rising financing initiatives for the development of various biotechnology research activities including the extensive use of competent cells will aid in the market's expansion. Further, the U.S. market of Competent Cells held the largest market share, and the Canada market of Competent Cells was the fastest growing market in the North America region.


Further, the major countries studied in the market report are The U.S., Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2: COMPETENT CELLS MARKET SHARE BY REGION 2022 (%)


COMPETENT CELLS MARKET SHARE BY REGION


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe Competent Cells market is predicted to grow, Due to the increased commercial demand for recombinant products and strong research efforts in recombinant therapies due to technological advancement within the area. Further, the German market of Competent Cells held the largest market share, and the UK market of Competent Cells was the fastest growing market in the European region.


The Asia-Pacific Competent Cells market is expected to grow at the fastest CAGR from 2023 to 2032. The expansion is attributed to extensive research on DNA cloning techniques in the field and the presence of large market players. For instance, Takara Bio Inc. announced in January 2021 that its new production and research facility, the Center for Gene and Cell Processing II, had been completed in Shiga, Japan. Further, China’s market of Competent Cells held the largest market share, and the Indian market of Competent Cells was the fastest growing market in the Asia-Pacific region.


Competent Cells Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development in order to expand their Product lines, which will help the market of Competent Cells, grow even more. Market participants are also undertaking a variety of strategic activities to expand their global footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Competent Cells industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the global Competent Cells industry to benefit clients and increase the market sector. In recent years, the Competent Cells industry has offered some of the most significant advantages to medicine. Major players in the Competent Cells market, including Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Inc., Takara Bio Inc., New England Biolabs (UK) Ltd., HiMedia Laboratories, Zymo Research, Avantor, TransGen Biotech Co., Ltd, Scarab Genomics, Lucigen Corporation, Genscript Corporation, Tonbo Biosciences, Enzynomics co Ltd, Klee GmbH, and NZYTech, Lda, are attempting to increase market demand by investing in research and development operations.


An innovative technology platform being developed by Epic Bio, a young biotechnology startup, can offer secure and ongoing control of precise gene regulation. Our unique platform is a completely new class of medicines that can be used to treat severe disease in many different therapeutic areas, including multigene complex diseases. Without regard to race, color, religion, age, sex, national origin, genetics, disability status, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws, Epic Bio offers equal employment opportunities to all employees and job applicants and forbids harassment of any kind. A series fundraising round totaling USD 55 million was launched by Epic-Bio in July 2022. Epic-Bio has created ultra-compact medicines to control gene expression in vivo.


A clinical-stage biotechnology business called RegenxBio Inc (RegenxBio), originally ReGenX Biosciences LLC, is engaged in the research and development of gene therapy. Treatment of numerous retinal, metabolic, and neurodegenerative illnesses is its main focus. Recombinant adeno associated virus (AAV) gene therapy is created, offered for sale, and licensed by the business. AAV plasmids, AAV vector reporter systems, and customized AAV vectors are available from RegenxBio. The company's gene therapy product candidates give cells the ability to manufacture therapeutic proteins or antibodies that fight disease by addressing genetic abnormalities. To advance its pharmaceutical prospects, RegenxBio uses the gene delivery technique included in its unique NAV technology platform. The U.S. city of Rockville, Maryland, is where RegenxBio is based. In order to produce gene treatments on a large scale, RegenxBio opened a new internal facility in the United States in June 2022. To ensure total control of gene therapy manufacturing at the center, the corporation committed USD 65 million.


Key Companies in the Competent Cells market include



  • Thermo Fisher Scientific

  • Merck KGaA

  • Agilent Technologies, Inc.

  • Takara Bio Inc.

  • New England Biolabs (UK) Ltd.

  • HiMedia Laboratories

  • Zymo Research

  • Avantor

  • TransGen Biotech Co., Ltd

  • Scarab Genomics

  • Lucigen Corporation

  • Genscript Corporation

  • Tonbo Biosciences

  • Enzynomics co Ltd

  • Klee GmbH

  • NZYTech, Lda


Competent Cells Industry Developments


October 2022 The outstanding LEAD team in Germany developed a Competence Center while collaborating with numerous German partner businesses. It is founded on reliable supply chains and long-term strategic partnerships with the best possible standardized solutions, whose global presence has quickly gained the confidence of several crucial big European companies.


October 2022 Immune-Onc Therapeutics, a clinical-stage cancer immunotherapy firm, has joined forces with BeiGene to collaborate on clinical trials for its first myeloid checkpoint inhibitor, the anti-PD-1 antibody tislelizumab. Their goal is to create innovative biotherapies that target myeloid checkpoints, which can lead to T cell activation in vitro, improve dendritic cell function, and impede tumor growth in an in vivo immunocompetent model. Immune-Onc is a privately held company.


Competent Cells Market Segmentation


Competent Cells Type Outlook



  • Chemically Competent Cells

  • Electrocompetent Cells


Competent Cells Application Outlook



  • Cloning

  • Protein Expression

  • Other Application


Competent Cells End-User Outlook



  • Pharmaceutical and Biotechnology Companies

  • Academic Research Institutes

  • Others


Competent Cells Regional Outlook




  • North America

    • US.

    • Canada




  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe




  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific




  • Rest of the World

    • Middle East

    • Africa

    • Latin America



Report Attribute/Metric Details
Market Size 2022 USD 1.9 Billion
Market Size 2023 USD 2.1 Billion
Market Size 2032 USD 4.8 Billion
Compound Annual Growth Rate (CAGR) 10.90% (2023-2032)
Base Year 2022
Market Forecast Period 2023-2032
Historical Data 2018- 2022
Market Forecast Units Value (USD Billion)
Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered Type, Application, End-User, and Region
Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
Countries Covered The U.S., Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Inc., Takara Bio Inc., New England Biolabs (UK) Ltd., HiMedia Laboratories, Zymo Research, Avantor, TransGen Biotech Co., Ltd, Scarab Genomics, Lucigen Corporation, Genscript Corporation, Tonbo Biosciences, Enzynomics co Ltd, Klee GmbH, and NZYTech, Lda
Key Market Opportunities The increasing usage of competent cells in the research and development activities
Key Market Dynamics Advancements in molecular cloning research due to the emergence of new technologies and increasing commercial demand for molecular cloned products and recombinant proteins


Frequently Asked Questions (FAQ) :

The Competent Cells Market size was valued at USD 1.9 Billion in 2022.

The global market is projected to grow at a CAGR of 10.90% during the forecast period, 2023-2032.

North America had the largest share in the global market

The key players in the market are Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Inc., Takara Bio Inc., New England Biolabs (UK) Ltd., HiMedia Laboratories, Zymo Research, Avantor, TransGen Biotech Co., Ltd, Scarab Genomics, Lucigen Corporation, Genscript Corporation, Tonbo Biosciences, Enzynomics co Ltd, Klee GmbH, and NZYTech, Lda.

The Chemically Competent Cells Type dominated the market in 2022.

The Cloning Application had the largest share in the global market.

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