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Choroidal Neovascularization Market

ID: MRFR/HC/25867-HCR
100 Pages
Rahul Gotadki
October 2025

Choroidal Neovascularization Market Research Report By Treatment Type (Anti-Angiogenic Therapy, Laser Photocoagulation, Photodynamic Therapy, Verteporfin Sodium, Ranibizumab, Bevacizumab, Aflibercept, Pegaptanib Sodium), By Indication (Age-Related Macular Degeneration (AMD), Diabetic Macular Edema (DME), Central Serous Chorioretinopathy (CSC), Polypoidal Choroidal Vasculopathy (PCV), Myopic Macular Degeneration (MMD), Other Indications), By Route of Administration (Intravitreal, Subconjunctival, Periocular, Oral), By End User (Hospitals, Oph... read more

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Choroidal Neovascularization Market Summary

As per MRFR analysis, the Choroidal Neovascularization Market Size was estimated at 1.916 USD Billion in 2024. The Choroidal Neovascularization industry is projected to grow from 2.043 USD Billion in 2025 to 3.887 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 6.64 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Choroidal Neovascularization Market is poised for substantial growth driven by innovative therapies and increasing awareness.

  • The emergence of novel therapeutics is reshaping treatment paradigms in the Choroidal Neovascularization Market.
  • North America remains the largest market, while the Asia-Pacific region is recognized as the fastest-growing area for these therapies.
  • Anti-Angiogenic Therapy continues to dominate the market, whereas Photodynamic Therapy is experiencing rapid growth.
  • Rising prevalence of eye disorders and advancements in diagnostic technologies are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 1.916 (USD Billion)
2035 Market Size 3.887 (USD Billion)
CAGR (2025 - 2035) 6.64%

Major Players

Regeneron Pharmaceuticals (US), Novartis (CH), Roche (CH), Bayer (DE), Pfizer (US), Amgen (US), Santen Pharmaceutical (JP), Eyenovia (US)

Choroidal Neovascularization Market Trends

The Choroidal Neovascularization Market is currently experiencing notable developments driven by advancements in treatment modalities and increasing awareness of eye health. The rise in the prevalence of age-related macular degeneration and other retinal disorders has led to a heightened demand for effective therapies. Pharmaceutical companies are actively engaged in research and development, focusing on innovative drug formulations and delivery systems. This dynamic environment suggests a potential for growth as new therapies emerge, aiming to improve patient outcomes and quality of life. Moreover, the market landscape is influenced by the integration of technology in treatment approaches. The advent of telemedicine and digital health solutions appears to facilitate better patient monitoring and access to care. As healthcare systems evolve, the Choroidal Neovascularization Market may witness a shift towards personalized medicine, where treatments are tailored to individual patient needs. This trend indicates a promising future for both patients and healthcare providers, as they navigate the complexities of managing choroidal neovascularization effectively.

Emergence of Novel Therapeutics

The Choroidal Neovascularization Market is witnessing a surge in the development of novel therapeutics. Pharmaceutical companies are exploring innovative compounds that target specific pathways involved in neovascularization. This trend suggests a shift towards more effective and targeted treatment options, potentially enhancing patient outcomes.

Technological Integration in Treatment

The integration of technology into treatment protocols is becoming increasingly prevalent within the Choroidal Neovascularization Market. Digital health solutions and telemedicine are facilitating improved patient engagement and monitoring, which may lead to better management of the condition.

Focus on Personalized Medicine

There is a growing emphasis on personalized medicine within the Choroidal Neovascularization Market. Tailoring treatments to individual patient profiles could enhance therapeutic efficacy and minimize adverse effects, indicating a significant shift in how care is delivered.

Choroidal Neovascularization Market Drivers

Rising Prevalence of Eye Disorders

The increasing incidence of eye disorders, particularly age-related macular degeneration (AMD), is a primary driver of the Choroidal Neovascularization Market. As populations age, the prevalence of AMD and other retinal diseases rises, leading to a greater demand for effective treatment options. According to recent estimates, AMD affects millions worldwide, with projections indicating that the number of affected individuals could reach 288 million by 2040. This surge in cases necessitates innovative therapies and interventions, thereby propelling the growth of the Choroidal Neovascularization Market. Furthermore, the growing awareness of eye health and the importance of early diagnosis contribute to the rising demand for specialized treatments, creating a robust market environment for stakeholders involved in this sector.

Advancements in Diagnostic Technologies

Technological advancements in diagnostic tools are significantly influencing the Choroidal Neovascularization Market. Enhanced imaging techniques, such as optical coherence tomography (OCT) and fundus photography, allow for earlier and more accurate detection of choroidal neovascularization. These innovations facilitate timely intervention, which is crucial for improving patient outcomes. The market for diagnostic devices is projected to grow, with estimates suggesting a compound annual growth rate (CAGR) of over 6% in the coming years. As healthcare providers increasingly adopt these advanced diagnostic technologies, the demand for subsequent therapeutic interventions is likely to rise, further stimulating the Choroidal Neovascularization Market. This trend underscores the importance of integrating cutting-edge technology into clinical practice to enhance patient care.

Growing Awareness and Education Initiatives

The rise in awareness and education initiatives regarding eye health is a crucial driver for the Choroidal Neovascularization Market. Organizations and healthcare providers are increasingly focusing on educating the public about the risks associated with retinal diseases and the importance of regular eye examinations. This heightened awareness is likely to lead to earlier diagnosis and treatment of choroidal neovascularization, thereby expanding the market. Campaigns aimed at promoting eye health have shown positive results, with surveys indicating that individuals who are informed about eye conditions are more likely to seek medical advice. Consequently, this trend is expected to bolster the demand for therapies and interventions within the Choroidal Neovascularization Market, creating a more informed patient population.

Regulatory Support for Innovative Treatments

Regulatory bodies are increasingly providing support for the development and approval of innovative treatments within the Choroidal Neovascularization Market. Initiatives aimed at expediting the review process for new therapies, such as breakthrough therapy designations and fast-track approvals, are encouraging pharmaceutical companies to invest in the development of novel solutions. This regulatory environment fosters innovation and enhances the availability of effective treatments for patients suffering from choroidal neovascularization. Recent data suggests that the approval timelines for new ophthalmic drugs have decreased, allowing for quicker access to therapies. As regulatory support continues to evolve, it is likely to stimulate growth in the Choroidal Neovascularization Market, ultimately benefiting patients and healthcare providers.

Increased Investment in Research and Development

The Choroidal Neovascularization Market is experiencing a surge in investment directed towards research and development (R&D) initiatives. Pharmaceutical companies and biotechnology firms are allocating substantial resources to discover and develop novel therapies targeting choroidal neovascularization. This focus on R&D is driven by the need for more effective treatments that can address the underlying causes of retinal diseases. Recent reports indicate that global spending on R&D in the pharmaceutical sector has reached approximately 200 billion, with a significant portion dedicated to ophthalmic research. As new therapies emerge from these investments, they are expected to enhance treatment options available in the Choroidal Neovascularization Market, ultimately benefiting patients and healthcare providers alike.

Market Segment Insights

By Treatment Type: Anti-Angiogenic Therapy (Largest) vs. Photodynamic Therapy (Fastest-Growing)

In the Choroidal Neovascularization Market, the distribution of market share among various treatment types is indicative of the growing importance of specific therapies. Anti-angiogenic therapy, including agents like Ranibizumab, Aflibercept, and Bevacizumab, holds the largest share due to its effectiveness in managing neovascular age-related macular degeneration. Conversely, treatments such as Laser Photocoagulation and Photodynamic Therapy are prevalent yet represent a smaller portion of the market as they become less favorable compared to advanced anti-angiogenic options.

Anti-Angiogenic Therapy (Dominant) vs. Photodynamic Therapy (Emerging)

Anti-angiogenic therapies are at the forefront of the treatment landscape for choroidal neovascularization, particularly Ranibizumab and Aflibercept, which are recognized for their ability to inhibit neovascularization effectively. These therapies are widely adopted due to their proven results in improving vision and stabilizing choroidal neovascularization. On the other hand, Photodynamic Therapy, including Verteporfin Sodium, is considered an emerging treatment modality. Although it shows promise in specific patient populations, its market position is hindered by the dominance of newer anti-angiogenic agents. Nevertheless, ongoing research and clinical trials may enhance its adoption, reflecting a potential shift in preference among healthcare providers.

By Indication: Age-Related Macular Degeneration (AMD) (Largest) vs. Diabetic Macular Edema (DME) (Fastest-Growing)

The Choroidal Neovascularization Market is characterized by significant diversity across its indications, with Age-Related Macular Degeneration (AMD) capturing the largest market share. This segment has consistently demonstrated its dominance, driven by a growing elderly population and increased awareness of eye diseases. Following closely is Diabetic Macular Edema (DME), which is emerging rapidly due to rising diabetes prevalence, showcasing a growing segment that is gaining traction in therapeutic advancements. Furthermore, Central Serous Chorioretinopathy (CSC), Polypoidal Choroidal Vasculopathy (PCV), and Myopic Macular Degeneration (MMD) contribute to the overall market dynamics, albeit at a smaller scale. The growth trends indicate a shift towards innovative treatment options, with current research focusing on personalized medicine. Novel therapies improving patient outcomes are anticipated to drive the market, particularly in indications like DME, where treatment advancements are expected to address unmet medical needs.

AMD (Dominant) vs. DME (Emerging)

Age-Related Macular Degeneration (AMD) stands out as the dominant indication in the Choroidal Neovascularization Market, primarily due to its widespread prevalence among the aging population. This indication significantly shapes market strategies, with numerous pharmaceutical companies focusing their R&D efforts on developing novel therapies and interventions specifically targeting AMD. On the other hand, Diabetic Macular Edema (DME) is recognized as an emerging force within the market, fueled by the increasing incidence of diabetes globally. The therapeutic landscape for DME is evolving, with innovative treatments being introduced that enhance visual outcomes and manage disease progression. The juxtaposition of AMD's established market presence with DME's rapid growth creates a dynamic environment in the Choroidal Neovascularization Market.

By Route of Administration: Intravitreal (Largest) vs. Subconjunctival (Fastest-Growing)

In the Choroidal Neovascularization Market, the Route of Administration segment showcases Intravitreal as the largest contributor, commanding a substantial share. This method allows for direct delivery of therapeutic agents to the vitreous humor, optimizing treatment efficacy for patients. In contrast, Subconjunctival administration, while smaller in market size, is rapidly gaining traction due to its minimal invasiveness and patient compliance benefits. As healthcare providers seek more patient-friendly options, Subconjunctival injections are positioned for significant growth.

Intravitreal (Dominant) vs. Subconjunctival (Emerging)

Intravitreal administration remains the dominant route in treating Choroidal Neovascularization Market, primarily due to its targeted delivery mechanism that directly addresses the affected area, resulting in rapid onset of action. This method is particularly favored for its effectiveness in delivering biological agents like monoclonal antibodies. Conversely, Subconjunctival administration is emerging as a favorable alternative, offering advantages such as lower patient discomfort and ease of administration. With ongoing advancements in drug formulations and techniques, Subconjunctival methods are likely to witness increased adoption, appealing to both physicians and patients looking for less invasive treatment options.

By End User: Hospitals (Largest) vs. Ophthalmology Clinics (Fastest-Growing)

In the Choroidal Neovascularization Market, hospitals represent the largest end user segment, largely due to their comprehensive treatment capabilities and advanced facilities. They are well-equipped to handle a high volume of complex cases, which contributes significantly to their market share. Conversely, ophthalmology clinics, while smaller in market share, are rapidly gaining traction. Their specialized focus on eye health enables them to provide tailored services, making them increasingly popular among patients seeking specific treatments for conditions like choroidal neovascularization.

Ophthalmology Clinics: Emerging vs. Research Centers: Dominant

Ophthalmology clinics have emerged as a vital player in the Choroidal Neovascularization Market, offering focused and specialized treatment solutions that cater to patients' specific needs. These clinics are often more agile in adopting new technologies and treatment methodologies, which appeals to a growing patient base seeking cutting-edge care. In contrast, research centers hold a dominant position by driving innovation and conducting pivotal studies in the field. Their contributions to understanding disease mechanisms and developing new therapies position them as essential players in shaping future treatment paradigms.

Get more detailed insights about Choroidal Neovascularization Market

Regional Insights

North America : Leading Innovation and Research

North America is the largest market for Choroidal Neovascularization Market (CNV) treatments, holding approximately 45% of the global market share. The region benefits from advanced healthcare infrastructure, high prevalence of age-related macular degeneration, and significant investments in research and development. Regulatory support from agencies like the FDA further catalyzes market growth, ensuring timely approvals for innovative therapies. The United States is the primary contributor, with key players such as Regeneron Pharmaceuticals and Pfizer leading the charge. Canada also plays a significant role, albeit smaller, focusing on expanding access to treatments. The competitive landscape is characterized by a mix of established pharmaceutical giants and emerging biotech firms, all vying for market share in this lucrative sector.

Europe : Regulatory Framework and Growth

Europe is the second-largest market for Choroidal Neovascularization Market, accounting for approximately 30% of the global market share. The region's growth is driven by increasing awareness of eye diseases, advancements in treatment options, and supportive regulatory frameworks. The European Medicines Agency (EMA) plays a crucial role in facilitating the approval of new therapies, which enhances patient access to innovative treatments. Leading countries include Germany, France, and the UK, where healthcare systems are increasingly adopting new technologies. Major players like Novartis and Roche are actively involved in research and development, contributing to a competitive landscape that fosters innovation. The presence of numerous clinical trials further indicates a robust pipeline of potential therapies aimed at addressing CNV.

Asia-Pacific : Emerging Market Potential

The Asia-Pacific region is witnessing rapid growth in the Choroidal Neovascularization Market, driven by increasing healthcare expenditure and rising awareness of eye health. This region holds approximately 20% of the global market share, with countries like Japan and China leading the charge. The growing elderly population and the prevalence of chronic diseases are significant factors contributing to market expansion, alongside supportive government initiatives aimed at improving healthcare access. Japan is a key player, with companies like Santen Pharmaceutical making strides in innovative treatments. China is also emerging as a significant market, with increasing investments in healthcare infrastructure. The competitive landscape is evolving, with both local and international players vying for market presence, indicating a promising future for CNV treatments in this region.

Middle East and Africa : Untapped Market Potential

The Middle East and Africa (MEA) region represents an emerging market for Choroidal Neovascularization Market treatments, holding about 5% of the global market share. The growth in this region is primarily driven by increasing healthcare investments and a rising prevalence of eye diseases. Governments are focusing on enhancing healthcare infrastructure, which is expected to catalyze market growth in the coming years, despite existing challenges such as limited access to advanced therapies. Countries like South Africa and the UAE are leading the way in adopting new treatment modalities. The competitive landscape is characterized by a mix of local and international players, with companies exploring partnerships to enhance their market presence. As awareness of CNV grows, the potential for market expansion in this region is significant, paving the way for innovative solutions.

Choroidal Neovascularization Market Regional Image

Key Players and Competitive Insights

The major players in the Choroidal Neovascularization Market are focused continuously on the development of novel therapeutic approaches to address the unmet medical needs of patients with CNV.

Leading Choroidal Neovascularization Market players are involved in clinical trials, research collaborations, and strategic partnerships to fortify their product portfolios and expand their market presence.

The competitive Choroidal Neovascularization Market landscape is a mix of both established pharmaceutical companies and emerging biotechnology ventures. Novartis, Bayer, Roche, Regeneron, and Allergan are the key players in the Choroidal Neovascularization Market.

These companies are spending on research and development activities to develop innovative therapies targeting the underlying cause of CNV and improve patient outcomes. The Choroidal Neovascularization Market has excellent growth potential in the upcoming years due to the growing prevalence of age-related macular degeneration and diabetic retinopathy and the development of novel therapeutic approaches.

Novartis is one of the leading players in the Choroidal Neovascularization Market with a strong presence in ophthalmology. The company’s present portfolio includes Lucentis ranibizumab, which is a VEGF inhibitor approved for the treatment of wet age-related macular degeneration and other retinal diseases.

Novartis has a robust pipeline of new therapies for CNV, including brolucizumab, a new drug showing superior effects in clinical trials. This new drug is also a strong contender for a blockbuster position in the near future. Novartis’ POS is high due to its strong commercial presence and commitment to innovation.

Bayer is another prominent player in the Choroidal Neovascularization Market with a stronghold in ophthalmology. The company’s present portfolio includes Eylea aflibercept, a VEGF inhibitor approved for the treatment of wet age-related macular degeneration, diabetic retinopathy, and other retinal diseases.

The company's current drug being developed for CNV is farcical. The biggest strength of Bayer in the Choroidal Neovascularization Market is its strong product portfolio and commitment to Research and Development.

Key Companies in the Choroidal Neovascularization Market market include

Industry Developments

Key factors driving this growth include the increasing prevalence of age-related macular degeneration (AMD), the leading cause of CNV, as well as advancements in treatment modalities such as anti-vascular endothelial growth factor (VEGF) therapies.

Geographic regions with high geriatric populations, such as North America and Europe, are expected to hold significant market shares.

Recent developments in the CNV market include the approval of novel anti-VEGF agents with improved efficacy and safety profiles, as well as the emergence of gene therapy approaches targeting the underlying genetic causes of CNV.

Future Outlook

Choroidal Neovascularization Market Future Outlook

The Choroidal Neovascularization Market is projected to grow at a 6.64% CAGR from 2024 to 2035, driven by advancements in treatment modalities and increasing prevalence of age-related macular degeneration.

New opportunities lie in:

  • Development of targeted gene therapies for enhanced treatment efficacy.
  • Expansion of telemedicine platforms for remote patient monitoring.
  • Investment in AI-driven diagnostic tools to improve early detection.

By 2035, the Choroidal Neovascularization Market is expected to achieve substantial growth and innovation.

Market Segmentation

Choroidal Neovascularization Market End User Outlook

  • Hospitals
  • Ophthalmology Clinics
  • Ambulatory Surgical Centers
  • Research Centers

Choroidal Neovascularization Market Indication Outlook

  • Age-Related Macular Degeneration (AMD)
  • Diabetic Macular Edema (DME)
  • Central Serous Chorioretinopathy (CSC)
  • Polypoidal Choroidal Vasculopathy (PCV)
  • Myopic Macular Degeneration (MMD)
  • Other Indications

Choroidal Neovascularization Market Treatment Type Outlook

  • Anti-Angiogenic Therapy
  • Laser Photocoagulation
  • Photodynamic Therapy
  • Verteporfin Sodium
  • Ranibizumab
  • Bevacizumab
  • Aflibercept
  • Pegaptanib Sodium

Choroidal Neovascularization Market Route of Administration Outlook

  • Intravitreal
  • Subconjunctival
  • Periocular
  • Oral

Report Scope

MARKET SIZE 20241.916(USD Billion)
MARKET SIZE 20252.043(USD Billion)
MARKET SIZE 20353.887(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)6.64% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMarket analysis in progress
Segments CoveredMarket segmentation analysis in progress
Key Market OpportunitiesAdvancements in gene therapy and biologics enhance treatment options in the Choroidal Neovascularization Market.
Key Market DynamicsRising prevalence of age-related macular degeneration drives demand for innovative therapies in the Choroidal Neovascularization Market.
Countries CoveredNorth America, Europe, APAC, South America, MEA

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FAQs

What is the projected market valuation of the Choroidal Neovascularization Market by 2035?

The Choroidal Neovascularization Market is projected to reach a valuation of 3.887 USD Billion by 2035.

What was the market valuation of the Choroidal Neovascularization Market in 2024?

In 2024, the overall market valuation was 1.916 USD Billion.

What is the expected CAGR for the Choroidal Neovascularization Market during the forecast period 2025 - 2035?

The expected CAGR for the Choroidal Neovascularization Market during the forecast period 2025 - 2035 is 6.64%.

Which treatment type segment is projected to have the highest valuation by 2035?

The Anti-Angiogenic Therapy segment is projected to reach a valuation of 1.6 USD Billion by 2035.

What are the key indications driving the Choroidal Neovascularization Market?

Key indications include Age-Related Macular Degeneration (AMD) and Diabetic Macular Edema (DME), with AMD projected to reach 1.575 USD Billion by 2035.

Which route of administration is expected to dominate the market by 2035?

The Intravitreal route of administration is expected to dominate, with a projected valuation of 1.956 USD Billion by 2035.

What is the anticipated market performance of hospitals as an end user by 2035?

Hospitals are anticipated to reach a market valuation of 1.558 USD Billion by 2035.

Who are the key players in the Choroidal Neovascularization Market?

Key players include Regeneron Pharmaceuticals, Novartis, Roche, Bayer, Pfizer, Amgen, Santen Pharmaceutical, and Eyenovia.

What is the projected valuation for the Photodynamic Therapy segment by 2035?

The Photodynamic Therapy segment is projected to reach a valuation of 0.6 USD Billion by 2035.

How does the market for Central Serous Chorioretinopathy (CSC) appear to be evolving?

The market for Central Serous Chorioretinopathy (CSC) is projected to grow to 0.575 USD Billion by 2035.

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