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    US DNA Synthesis Market

    ID: MRFR/HC/51009-HCR
    200 Pages
    Rahul Gotadki
    September 2025

    US DNA Synthesis Market Research Report By Application (Gene Therapy, Synthetic Biology, Molecular Diagnostics, Vaccine Development), By Product Type (Oligonucleotides, Gene Fragments, Gene Libraries), By End User (Academic Research Institutions, Pharmaceutical Companies, Biotechnology Companies, Clinical Laboratories) and By Technology (Solid-Phase Synthesis, Liquid-Phase Synthesis, PCR-Based Synthesis) - Forecast to 2035

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    US DNA Synthesis Market Infographic
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    US DNA Synthesis Market Summary

    The United States DNA Synthesis market is projected to grow from 1.13 billion USD in 2024 to 3.03 billion USD by 2035.

    Key Market Trends & Highlights

    US DNA Synthesis Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate of 9.38 percent from 2025 to 2035.
    • By 2035, the DNA synthesis market in the United States is anticipated to reach 3.03 billion USD.
    • In 2024, the market valuation stands at 1.13 billion USD, indicating a robust growth trajectory.
    • Growing adoption of synthetic biology due to advancements in genetic engineering is a major market driver.

    Market Size & Forecast

    2024 Market Size 1.13 (USD Billion)
    2035 Market Size 3.03 (USD Billion)
    CAGR (2025-2035) 9.38%

    Major Players

    Agilent Technologies, Eurofins Genomics, Thermo Fisher Scientific, Codexis, Synlogic, Bioneer, Twist Bioscience, Genomatix, Illumina, GeneScript, Pacific Biosciences, BioRad Laboratories, Interpretive Genetics, Integrated DNA Technologies

    US DNA Synthesis Market Trends

    The US DNA synthesis market is experiencing notable trends driven by various factors. A significant market driver is the increasing demand for synthetic DNA across various sectors, particularly in biotechnology and pharmaceuticals. The growing focus on personalized medicine has led to a rising requirement for tailored genomic solutions, fueling the synthesis of DNA for research and therapeutic applications. Furthermore, advancements in sequencing technologies and synthetic biology techniques are amplifying the efficiency and capability of DNA synthesis, making it more accessible to researchers and companies alike.

    Opportunities in the US DNA synthesis market are abundant, particularly with the ongoing research initiatives supported by government funding, such as those from the National Institutes of Health (NIH) and the Department of Energy (DOE). These initiatives aim to promote advancements in genomic research, biotechnology innovations, and even agricultural biotechnology, creating market space for new entrants and established firms looking to expand their capabilities. Recent trends indicate a growing collaboration between academic institutions and private companies in the DNA synthesis space.

    This collaboration often focuses on developing new applications for healthcare and agricultural purposes, combining academic research with practical industrial applications. Additionally, there is increasing interest in issues like biosecurity and ethical considerations surrounding synthetic biology, further shaping the landscape of the DNA synthesis market in the US. As the market matures, regulatory frameworks are also evolving, ensuring that innovations align with public health and safety standards, which is crucial for gaining public acceptance and further driving growth in the sector.

    Market Segment Insights

    US DNA Synthesis Market Segment Insights

    US DNA Synthesis Market Segment Insights

    DNA Synthesis Market Application Insights  

    DNA Synthesis Market Application Insights  

    The Application segment of the US DNA Synthesis Market holds significant value, with diverse applications ranging from Gene Therapy to Vaccine Development. This market is driven by the rapid advancements in biotechnology and a growing demand for precision medicine, impacting the overall landscape in profound ways. In Gene Therapy, the focus is on using engineered DNA to modify or repair genes, offering promising treatments for genetic disorders. This area is gaining momentum due to its potential to revolutionize the clinical approach to previously untreatable diseases.

    Similarly, Synthetic Biology leverages DNA synthesis to create new biological parts and systems, attracting substantial investment and interest for its ability to tackle challenges like biofuel production and agricultural enhancements. Molecular Diagnostics, meanwhile, is rapidly evolving, utilizing synthesized DNA to improve the accuracy and speed of disease detection, particularly in areas like oncology and infectious diseases, highlighting its crucial role in modern healthcare. Lastly, Vaccine Development has witnessed significant growth, especially in response to recent global health challenges, with DNA synthesis enabling faster and more efficient vaccine formulations.

    The interplay of these applications illustrates the dynamic nature of the US DNA Synthesis Market, driven by innovation and a response to urgent health needs, ensuring relevance in both research and clinical settings. Overall, the market is characterized by its robust activity, aiming to address some of the most pressing health issues, demonstrating its vital role in the broader context of biomedicine and public health strategy.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    DNA Synthesis Market Product Type Insights  

    DNA Synthesis Market Product Type Insights  

    The US DNA Synthesis Market is characterized by its diverse Product Type offerings, primarily including Oligonucleotides, Gene Fragments, and Gene Libraries, each playing a crucial role in various applications across Research and Development, diagnostics, and therapeutic developments. Oligonucleotides are pivotal in gene editing and molecular diagnostics, often considered the backbone of synthetic biology due to their versatility in targeting specific genetic sequences. Gene Fragments contribute significantly to the creation of recombinant proteins and gene therapies, enabling advancements in personalized medicine.

    Meanwhile, Gene Libraries serve as essential tools for genetic research, providing a vast reservoir of genetic materials that aid in discovering new genes and their functions. The market dynamics reflect an increasing dependency on these products to support innovations in genomics and biotechnology, driven by rising investments in genetic research. This collective growth indicates a trend toward higher integration of genomic solutions in healthcare, fueling overall market expansion within the US.

    DNA Synthesis Market End User Insights  

    DNA Synthesis Market End User Insights  

    The End User segment of the US DNA Synthesis Market showcases a diverse array of applications across various industries, highlighting its critical role in advancing genetic research and biotechnology. Academic Research Institutions are integral in driving innovation, focusing on fundamental DNA research and engaging in educational pursuits that lay the groundwork for future advancements. Pharmaceutical Companies leverage DNA synthesis for drug development, utilizing synthesized DNA for therapeutic uses and ensuring robust pipeline growth.

    Biotechnology Companies are pivotal as they implement DNA synthesis in the creation of genetically modified organisms and in the development of cutting-edge therapies, underlining their significance in addressing health challenges. Meanwhile, Clinical Laboratories are essential for diagnostic applications, employing synthesized DNA in genetic testing and personalized medicine, thus catering to the growing demand for tailored healthcare solutions. As a result, the US DNA Synthesis Market segmentation into these varied End Users reflects not only current technological trends but also the potential for future growth driven by advancements in genetic engineering and bioinformatics.

    Overall, this segment is poised for significant evolution as it addresses both academic inquiries and real-world health issues across multiple sectors.

    DNA Synthesis Market Technology Insights  

    DNA Synthesis Market Technology Insights  

    The Technology segment of the US DNA Synthesis Market is characterized by diverse methodologies that facilitate precise DNA production. Solid-Phase Synthesis is known for its robustness, enabling efficient assembly of custom oligonucleotides, which play a crucial role in Research and Development across various applications such as diagnostics and therapeutics. Similarly, Liquid-Phase Synthesis offers flexibility and scalability, making it suitable for large-scale projects in genomics and synthetic biology, where rapid results are essential. PCR-Based Synthesis is significant due to its widespread use in amplifying DNA fragments, instrumental in fields like genetic research and biotechnology.

    This segment has garnered immense attention owing to increasing demands for synthetic biology applications and advancements in genomic studies, reflecting a strong growth trajectory within the US. Moreover, the rise in personalized medicine and biopharmaceuticals further catalyzes the utility of these synthesis technologies, signifying their pivotal role in transforming scientific research and applications in the healthcare and agriculture sectors. As this segment continues to evolve, it presents ample opportunities for innovation and expansion, positioning itself at the forefront of the US DNA Synthesis Market industry.

    Get more detailed insights about US DNA Synthesis Market Research Report - Forecast to 2035

    Key Players and Competitive Insights

    The US DNA Synthesis Market has witnessed a remarkable evolution driven by advancements in biotechnology, increasing demand for personalized medicine, and the growing necessity for genetic research and synthetic biology applications. As this market expands, numerous players have emerged, each vying for competitive positioning through innovation, quality of service, and strategic partnerships. The competitive landscape is marked by both established and emerging firms that cater to various sectors, including academic research, pharmaceuticals, and agriculture. Organizations are leveraging cutting-edge technologies to enhance synthesis capabilities while addressing the complexities of customer requirements.

    As this dynamic environment continues to develop, understanding the competitive insights is crucial for firms aiming to excel and differentiate themselves within the marketplace. Agilent Technologies stands out in the US DNA Synthesis Market due to its strong commitment to providing high-quality synthesis solutions tailored to meet diverse customer needs. The company boasts a comprehensive portfolio that covers an array of applications from gene synthesis to custom oligonucleotide production. Agilent's state-of-the-art manufacturing facilities enable it to maintain rigorous quality control, ensuring the reliability and performance of its products.

    The company's strategic focus on research and development has also led to significant advancements in synthesis technologies, enhancing its ability to deliver rapid turnaround times and scalable solutions. Agilent Technologies leverages its extensive distribution networks to maintain a robust market presence, allowing it to effectively reach various sectors, including genomics, diagnostics, and therapeutics. Furthermore, its legacy of innovation and commitment to customer service have solidified its reputation as a leading player in the industry.

    Eurofins Genomics solidifies its position in the US DNA Synthesis Market by providing a range of high-quality synthetic products and services that cater to the needs of researchers and organizations in various fields. The company specializes in gene synthesis, oligos, and sequencing services, focusing on delivering fast and reliable results to meet the demands of modern scientific endeavors. Eurofins Genomics has strategically expanded its services through mergers and acquisitions, enhancing its capabilities and market footprint within the US.

    Their emphasis on quality assurance and technical support ensures that clients receive not only the products but also the expertise needed to drive their projects forward. Additionally, Eurofins Genomics maintains a commitment to innovation, continuously seeking advancements in its processes and technologies. This proactive approach, combined with the company's strong relationships in academia and industry, underscores its vital role in the competitive landscape of the US DNA Synthesis Market, positioning it favorably against its rivals.

    Key Companies in the US DNA Synthesis Market market include

    Industry Developments

    The US DNA Synthesis Market has seen notable advancements and developments recently. In September 2023, Agilent Technologies announced its expansion of synthetic biology capabilities, strengthening its position within the market and enhancing service offerings for clients. Concurrently, Thermo Fisher Scientific introduced new advancements to its GeneArt suite, enabling faster and more efficient DNA synthesis, which is likely to contribute to increasing market demand. Merger and acquisition activities are also noteworthy, with Twist Bioscience acquiring a leading synthetic biology firm in August 2023, thereby broadening its product portfolio.

    In the past couple of years, the market has witnessed significant growth, with a substantial increase in demand for custom DNA synthesis services due to rising investments in biotechnology and genomics, aligning with initiatives by the US government to promote innovation in life sciences. Companies like Illumina and Integrated DNA Technologies continue to expand their market presence through strategic collaborations and new product launches that address diverse needs within genomic research and therapeutic development. Overall, these factors contribute to a dynamic landscape in the US DNA Synthesis Market, reflective of ongoing technological advancements and increased applications in various sectors.

    Market Segmentation

    DNA Synthesis Market End User Outlook

    • Solid-Phase Synthesis
    • Liquid-Phase Synthesis
    • PCR-Based Synthesis

    DNA Synthesis Market Technology Outlook

    • Solid-Phase Synthesis
    • Liquid-Phase Synthesis
    • PCR-Based Synthesis

    DNA Synthesis Market Application Outlook

    • Oligonucleotides
    • Gene Fragments
    • Gene Libraries

    DNA Synthesis Market Product Type Outlook

    • Academic Research Institutions
    • Pharmaceutical Companies
    • Biotechnology Companies
    • Clinical Laboratories

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 1.04(USD Billion)
    Market Size 2024 1.13(USD Billion)
    Market Size 2035 3.03(USD Billion)
    Compound Annual Growth Rate (CAGR) 9.343% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Agilent Technologies, Eurofins Genomics, Thermo Fisher Scientific, Codexis, DNA2.0, Synlogic, Bioneer, Twist Bioscience, Genomatix, Illumina, GeneScript, Pacific Biosciences, BioRad Laboratories, Interpretive Genetics, Integrated DNA Technologies
    Segments Covered Application, Product Type, End User, Technology
    Key Market Opportunities Personalized medicine development, Synthetic biology innovations, Biopharmaceuticals manufacturing advancements, Genomic research expansion, Agricultural biotech applications
    Key Market Dynamics Increasing demand for personalized medicine, Advancements in synthetic biology, Growing biotech and pharmaceutical industries, Rising applications in agriculture, Enhanced research and development funding
    Countries Covered US

    FAQs

    What is the expected market size of the US DNA Synthesis Market in 2024?

    The US DNA Synthesis Market is expected to be valued at 1.13 billion USD in 2024.

    What is the projected market size of the US DNA Synthesis Market by 2035?

    By 2035, the US DNA Synthesis Market is projected to reach a value of 3.03 billion USD.

    What is the expected compound annual growth rate (CAGR) for the US DNA Synthesis Market from 2025 to 2035?

    The expected CAGR for the US DNA Synthesis Market from 2025 to 2035 is 9.343 percent.

    Which application will have the largest market share in the US DNA Synthesis Market in 2035?

    In 2035, Gene Therapy is projected to hold the largest market share, valued at 1.05 billion USD.

    What are the market sizes for the Synthetic Biology application in 2024 and 2035?

    The Synthetic Biology application is expected to be valued at 0.3 billion USD in 2024 and 0.8 billion USD by 2035.

    Which company is one of the key players in the US DNA Synthesis Market?

    Agilent Technologies is one of the notable key players in the US DNA Synthesis Market.

    What is the expected market value for Molecular Diagnostics in 2035?

    The expected market value for Molecular Diagnostics in 2035 is projected to be 0.65 billion USD.

    What is the anticipated market size for Vaccine Development in 2024?

    The anticipated market size for Vaccine Development in 2024 is valued at 0.18 billion USD.

    What opportunities exist in the US DNA Synthesis Market for the period 2025 to 2035?

    The growth in Gene Therapy, Synthetic Biology, and advancements in Molecular Diagnostics present significant opportunities from 2025 to 2035.

    What is one of the challenges facing the US DNA Synthesis Market?

    One of the challenges facing the US DNA Synthesis Market is the need for regulatory approvals in various applications.

    US DNA Synthesis Market Research Report - Forecast to 2035 Infographic
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