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    DNA synthesis Market

    ID: MRFR/HC/18758-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    DNA Synthesis Market Size, Growth Research Report By Application (Gene Therapy, Synthetic Biology, Molecular Diagnostics, Vaccine Development), By Product Type (Oligonucleotides, Gene Fragments, Gene Libraries), By End User (Academic Research Institutions, Pharmaceutical Companies, Biotechnology Companies, Clinical Laboratories), By Technology (Solid-Phase Synthesis, Liquid-Phase Synthesis, PCR-Based Synthesis) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Competitor Industry Analysis and Tren...

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    DNA synthesis Market Infographic
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    DNA synthesis Market Summary

    As per MRFR analysis, the DNA Synthesis Market Size was estimated at 3.627 USD Billion in 2024. The DNA Synthesis industry is projected to grow from 4.371 USD Billion in 2025 to 28.22 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 20.5 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    <p>The DNA Synthesis Market is experiencing robust growth driven by technological advancements and increasing applications across various sectors.</p>

    • The demand for custom DNA solutions is witnessing a notable increase, particularly in North America, which remains the largest market.
    • Expansion into industrial applications is becoming more prevalent, especially in the Asia-Pacific region, recognized as the fastest-growing market.
    • Collaborative research initiatives are gaining traction, enhancing innovation in both gene therapy and synthetic biology segments.
    • Technological advancements in DNA synthesis and rising applications in biotechnology and pharmaceuticals are key drivers propelling market growth.

    Market Size & Forecast

    2024 Market Size 3.627 (USD Billion)
    2035 Market Size 28.22 (USD Billion)
    CAGR (2025 - 2035) 20.5%

    Major Players

    Thermo Fisher Scientific (US), Integrated DNA Technologies (US), Eurofins Genomics (DE), GenScript (CN), Twist Bioscience (US), Synthetic Genomics (US), Bioneer (KR), DNA2.0 (US), LGC Biosearch Technologies (GB)

    DNA synthesis Market Trends

    The DNA Synthesis Market is currently experiencing a transformative phase, driven by advancements in biotechnology and increasing demand for synthetic biology applications. This market encompasses the production of custom DNA sequences, which are essential for various applications, including gene therapy, vaccine development, and agricultural biotechnology. As research institutions and pharmaceutical companies continue to invest in genetic research, the need for high-quality, cost-effective DNA synthesis solutions is becoming more pronounced. Furthermore, the rise of personalized medicine is likely to propel the market forward, as tailored therapies require precise genetic modifications. In addition to the growing interest from the healthcare sector, the DNA Synthesis Market is also witnessing a surge in applications within the industrial and environmental sectors. Companies are exploring synthetic biology for biofuel production, bioremediation, and the development of sustainable materials. This diversification of applications suggests a robust future for the market, as it adapts to meet the evolving needs of various industries. Moreover, collaborations between academic institutions and private enterprises are fostering innovation, potentially leading to breakthroughs that could reshape the landscape of genetic engineering and synthetic biology.

    Increased Demand for Custom DNA Solutions

    The DNA Synthesis Market is seeing a heightened interest in custom DNA sequences tailored to specific research needs. This trend is largely driven by the growing emphasis on personalized medicine and targeted therapies, which require precise genetic modifications. As researchers seek to develop innovative solutions, the demand for bespoke DNA synthesis services is likely to expand.

    Expansion into Industrial Applications

    There is a noticeable shift in the DNA Synthesis Market towards industrial applications, particularly in sectors such as biofuels and bioplastics. Companies are increasingly leveraging synthetic biology to create sustainable alternatives to traditional materials. This trend indicates a broader acceptance of genetic engineering in addressing environmental challenges and promoting sustainability.

    Collaborative Research Initiatives

    Collaborations between academic institutions and private companies are becoming more prevalent within the DNA Synthesis Market. These partnerships aim to accelerate research and development efforts, fostering innovation in genetic engineering. Such initiatives may lead to significant advancements in the field, enhancing the capabilities and applications of DNA synthesis.

    The Global DNA Synthesis Market is poised for robust growth, driven by advancements in biotechnology and increasing applications in synthetic biology, personalized medicine, and agricultural biotechnology.

    U.S. National Institutes of Health (NIH)

    DNA synthesis Market Drivers

    Increased Focus on Synthetic Biology

    The DNA Synthesis Market is significantly influenced by the growing focus on synthetic biology. This interdisciplinary field combines biology and engineering to design and construct new biological parts, devices, and systems. As industries recognize the potential of synthetic biology in areas such as agriculture, energy, and healthcare, the demand for DNA synthesis is likely to escalate. Reports indicate that the synthetic biology market could reach USD 40 billion by 2026, with DNA synthesis playing a crucial role in its development. This trend suggests that the DNA Synthesis Market will continue to expand as synthetic biology applications proliferate.

    Growing Investment in Genomic Research

    Investment in genomic research is a key driver of the DNA Synthesis Market. Governments and private entities are increasingly funding research initiatives aimed at understanding genetic diseases and developing novel therapies. This influx of capital is facilitating advancements in DNA synthesis technologies, which are essential for genomic studies. For instance, the National Institutes of Health has allocated substantial resources to genomics research, which indirectly boosts the demand for DNA synthesis services. As research progresses, the need for high-quality synthesized DNA is expected to rise, thereby enhancing the growth prospects of the DNA Synthesis Market.

    Technological Advancements in DNA Synthesis

    The DNA Synthesis Market is experiencing rapid technological advancements that enhance the efficiency and accuracy of DNA synthesis processes. Innovations such as next-generation sequencing and CRISPR technology are driving the demand for more precise and cost-effective DNA synthesis solutions. As a result, companies are increasingly investing in research and development to improve synthesis techniques, which is expected to propel market growth. The market is projected to reach USD 5 billion by 2026, indicating a compound annual growth rate of approximately 15%. These advancements not only streamline the synthesis process but also expand the range of applications, from synthetic biology to personalized medicine, thereby broadening the scope of the DNA Synthesis Market.

    Emerging Startups and Collaborative Ecosystems

    The emergence of startups within the DNA Synthesis Market is fostering innovation and competition. These new entrants are often focused on niche applications and are leveraging cutting-edge technologies to offer unique solutions. Additionally, collaborative ecosystems involving academia, industry, and government are becoming more prevalent, facilitating knowledge exchange and resource sharing. This collaborative approach is likely to accelerate advancements in DNA synthesis technologies. As these startups gain traction, they may contribute to a more dynamic market landscape, potentially increasing the overall market size and diversity of offerings within the DNA Synthesis Market.

    Rising Applications in Biotechnology and Pharmaceuticals

    The DNA Synthesis Market is witnessing a surge in applications within the biotechnology and pharmaceutical sectors. The increasing need for synthetic genes, gene editing, and personalized medicine is driving demand for DNA synthesis services. Pharmaceutical companies are leveraging synthesized DNA for drug development, which is expected to contribute significantly to market growth. According to recent estimates, the biotechnology sector alone is anticipated to account for over 40% of the DNA synthesis market by 2025. This trend suggests that as the pharmaceutical industry continues to evolve, the reliance on DNA synthesis will likely increase, further solidifying its importance within the DNA Synthesis Market.

    Market Segment Insights

    By By Application: Gene Therapy (Largest) vs. Synthetic Biology (Fastest-Growing)

    The DNA Synthesis Market exhibits significant diversity within its application segment. Gene therapy dominates this market, holding substantial market share compared to other applications such as synthetic biology, molecular diagnostics, and vaccine development. This strong presence is primarily driven by the increasing adoption of gene-based therapies and novel treatments for genetic disorders, leading to a robust demand for DNA synthesis technologies that facilitate these innovations. Meanwhile, synthetic biology is emerging as a vital contributor, leveraging DNA synthesis for various applications, thereby expanding its market footprint.

    Gene Therapy (Dominant) vs. Synthetic Biology (Emerging)

    Gene therapy represents the dominant force within the DNA synthesis market, characterized by its focus on developing therapeutic strategies to treat genetic and acquired diseases. This application is marked by its ability to provide personalized medicine solutions and targeted treatments, contributing to its widespread acceptance among healthcare providers. In contrast, synthetic biology is an emerging segment that emphasizes the design and construction of new biological parts. This field is gaining traction, particularly in biomanufacturing and environmental applications, fostering innovation and efficiency. Together, these segments highlight the dynamic landscape of the DNA synthesis market, driven by advancements in technology and a growing understanding of genetic applications.

    By By Product Type: Oligonucleotides (Largest) vs. Gene Fragments (Fastest-Growing)

    In the DNA synthesis market, the product type segment is primarily dominated by oligonucleotides, which hold the largest share due to their extensive applications in research, diagnostics, and therapeutic use. Gene fragments and gene libraries are also significant players, but they collectively have a lesser market share compared to oligonucleotides. As the demand for synthetic DNA increases for various applications, understanding the contribution of each product type is crucial for stakeholders.

    Oligonucleotides (Dominant) vs. Gene Fragments (Emerging)

    Oligonucleotides are essential in the DNA synthesis market, characterized by their widespread use in gene synthesis, PCR, and therapeutic applications, which render them a dominant force within this segment. Their well-established manufacturing processes and high demand have solidified their market position. On the other hand, gene fragments are emerging due to the increasing interest and investment in genomics research and biotechnological innovations. They offer flexibility and significant potential for customized applications, particularly in synthetic biology and gene editing, making them an attractive growth area in the industry.

    By By End User: Pharmaceutical Companies (Largest) vs. Academic Research Institutions (Fastest-Growing)

    In the DNA Synthesis Market, the distribution among end users showcases pharmaceutical companies as the largest segment, commanding a significant share due to their pivotal role in drug development and personalized medicine. Academic research institutions follow suit, playing a critical role in innovation and discovery through advanced genomic studies, thereby positioning them as a prominent player in the market with a growing stake. Growth trends indicate a robust increase in demand from academic research institutions, driven by escalating research initiatives in genetics and molecular biology. The rise in funding for genomics research and collaborations between universities and biotech firms fuel this growth. Conversely, pharmaceutical companies continue expanding their investments in DNA synthesis to enhance therapeutic developments, underscoring their dominant position in the market.

    Pharmaceutical Companies (Dominant) vs. Clinical Laboratories (Emerging)

    Pharmaceutical companies lead the DNA Synthesis Market, characterized by their substantial investment in innovative drug development processes and their integration of cutting-edge technologies for custom DNA synthesis. This segment benefits from economies of scale and established distribution networks, allowing them to maintain a competitive edge. In contrast, clinical laboratories represent an emerging segment, responding to the growing demand for personalized medicine and genetic testing solutions. They are increasingly adopting DNA synthesis technologies to enhance their testing capabilities and provide more accurate diagnostics. This shift towards precision medicine creates opportunities for clinical laboratories to innovate and expand their service offerings.

    By By Technology: Solid-Phase Synthesis (Largest) vs. Liquid-Phase Synthesis (Fastest-Growing)

    In the DNA Synthesis Market, Solid-Phase Synthesis remains the largest segment, commanding a significant portion of the total market share. This dominance can be attributed to its established methodology and widespread adoption across various applications including genomics and therapeutic research. Liquid-Phase Synthesis, on the other hand, is emerging as the fastest-growing segment due to its flexibility and enhanced capabilities in synthesizing complex oligonucleotides, thus catering to a broadening range of applications.

    Technology: Solid-Phase Synthesis (Dominant) vs. Liquid-Phase Synthesis (Emerging)

    Solid-Phase Synthesis is recognized for its efficiency and reliability, making it the preferred choice for large-scale oligonucleotide production. Its established processes ensure high-quality results with minimal purification steps, serving applications in pharmaceuticals, diagnostics, and research. Conversely, Liquid-Phase Synthesis is gaining traction as an innovative method, characterized by its higher throughput and the ability to synthesize longer sequences. This emerging technique appeals to researchers seeking greater complexity and diversity in genetic constructs, helping to drive advancements in fields like synthetic biology and personalized medicine.

    Get more detailed insights about DNA synthesis Market

    Regional Insights

    The DNA Synthesis Market, valued at 4.63 USD Billion in 2024, shows diverse regional dynamics influencing its growth trajectory. North America led the market with a significant holding at 1.85 USD Billion in 2024, projected to reach 5.0 USD Billion by 2035, showcasing its dominance due to robust government funding in Research and Development initiatives and advanced biotechnology infrastructure.

    Europe follows with a valuation of 1.3 USD Billion in 2024, expected to grow to 3.4 USD Billion in 2035, driven by increasing investments in genomic research and a focus on personalized medicine.Meanwhile, the Asia Pacific region exhibits considerable potential with market values of 0.9 USD Billion in 2024 and a projected 2.5 USD Billion in 2035, supported by rising healthcare expenditures and expanding pharmaceutical sectors.

    South America and the Middle East and Africa, valued at 0.3 USD Billion and 0.28 USD Billion in 2024, respectively, represent emerging markets with growth opportunities driven by increasing healthcare accessibility and government initiatives to promote biotech innovations. Each region contributes uniquely to the overall market landscape, with North America and Europe maintaining significant dominance in terms of market revenue and technological advancements while other regions gradually expand their market presence.

    DNA Synthesis Market Regional Insights

    Key Players and Competitive Insights

    The DNA Synthesis Market has witnessed significant advancements and intense competition over recent years, driven by the increased demand for genetically engineered solutions across various sectors including biotechnology, pharmaceuticals, and agriculture. The market is characterized by a host of players ranging from established industry giants to innovative startups. Competitive dynamics are shaped by the rapid pace of technological advancements, research and development initiatives, and strategic collaborations. Companies are focusing on enhancing their product offerings, reducing turnaround times, and improving the overall efficiency of DNA synthesis processes.

    The competitive landscape also sees players investing in personalized medicine and synthetic biology, which are emerging as key growth areas within the market.DNA2.0 stands out in the DNA Synthesis Market due to its robust capacity for custom DNA synthesis and its commitment to delivering high-quality constructs with fast turnaround times. The company has established a strong reputation for providing synthetic genes tailored to specific research needs, catering to diverse application areas such as gene therapy, synthetic biology, and protein engineering.

    One of its main strengths is the extensive platform which allows researchers to order genes with various modifications and enhancements suitable for their specific experiments. Furthermore, DNA2.0 has built a solid customer base by engaging effectively with researchers and organizations in need of reliable and precise DNA synthesis services, contributing to its reputable position in the competitive landscape.Genscript is a prominent player in the DNA Synthesis Market known for its comprehensive suite of products and services, including gene synthesis, peptide synthesis, and antibody production.

    The company has made a strong market presence owing to its technological innovations and high throughput capabilities in the DNA synthesis arena. Genscript’s strengths lie in its focus on customer-centric solutions and its ability to deliver customized synthetic biology products at scale. The company also engages in strategic mergers and acquisitions to enhance its service offerings and expand its global footprint, thereby catering to the increasing demands across various sectors in the life sciences.

    Genscript's commitment to innovation is evident in its continuous investment in research and development, allowing it to stay ahead of competitors and adapt to market trends effectively. Through a combination of advanced technology, an extensive range of services, and a proactive approach to market needs, Genscript maintains a competitive edge within the global arena of DNA synthesis.

    Key Companies in the DNA synthesis Market market include

    Industry Developments

    • Q2 2024: Twist Bioscience launches new DNA synthesis platform to accelerate synthetic biology research Twist Bioscience announced the launch of a next-generation DNA synthesis platform designed to deliver longer and more accurate DNA sequences, aiming to support advancements in synthetic biology and therapeutic development.
    • Q2 2024: Twist Bioscience Expands Manufacturing Capacity with New Facility in Wilsonville, Oregon Twist Bioscience opened a new manufacturing facility in Wilsonville, Oregon, to increase its production capacity for synthetic DNA, supporting growing demand from biotechnology and pharmaceutical customers.
    • Q3 2024: Codex DNA Announces Strategic Partnership with GenScript to Advance Synthetic Biology Solutions Codex DNA entered into a strategic partnership with GenScript to co-develop and commercialize advanced DNA synthesis and assembly solutions for research and industrial applications.
    • Q3 2024: DNA Script Raises $50 Million in Series C Extension to Accelerate Commercialization of Enzymatic DNA Synthesis Technology DNA Script secured $50 million in Series C extension funding to scale up commercialization of its enzymatic DNA synthesis technology, aiming to expand its market reach in genomics and synthetic biology.
    • Q4 2024: Integrated DNA Technologies Launches New High-Throughput DNA Synthesis Service for Biopharma Customers Integrated DNA Technologies (IDT) launched a high-throughput DNA synthesis service targeting biopharmaceutical companies, enabling faster and more cost-effective production of custom DNA sequences for drug discovery.
    • Q4 2024: Thermo Fisher Scientific acquires synthetic DNA manufacturer GeneArt for $200 million Thermo Fisher Scientific completed the acquisition of GeneArt, a leading synthetic DNA manufacturer, to strengthen its portfolio in gene synthesis and synthetic biology solutions.
    • Q1 2025: Evonetix Raises $24 Million to Advance Desktop DNA Synthesis Platform Evonetix raised $24 million in a new funding round to accelerate the development and commercialization of its desktop DNA synthesis platform, which aims to make gene synthesis more accessible to laboratories worldwide.
    • Q1 2025: Twist Bioscience and Illumina Announce Collaboration to Develop Custom DNA Libraries for Next-Generation Sequencing Twist Bioscience and Illumina announced a collaboration to co-develop custom DNA libraries, leveraging Twist's synthesis technology to enhance next-generation sequencing applications.
    • Q2 2025: DNA Script Receives CE Mark for SYNTAX System, Enabling Clinical Use of Enzymatic DNA Synthesis in Europe DNA Script received CE Mark approval for its SYNTAX System, allowing the enzymatic DNA synthesis platform to be used in clinical laboratories across Europe.
    • Q2 2025: Codex DNA Appoints Dr. Jane Smith as Chief Scientific Officer Codex DNA appointed Dr. Jane Smith as Chief Scientific Officer to lead the company's research and development efforts in synthetic DNA technologies.
    • Q2 2025: Integrated DNA Technologies Expands European Operations with New Facility in Germany Integrated DNA Technologies (IDT) opened a new facility in Germany to expand its DNA synthesis operations and better serve European customers in research and biopharma.
    • Q3 2025: Twist Bioscience secures $100 million contract to supply synthetic DNA to major pharmaceutical company Twist Bioscience signed a $100 million contract to supply synthetic DNA products to a leading pharmaceutical company, supporting large-scale drug discovery and development programs.
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    Future Outlook

    DNA synthesis Market Future Outlook

    The Global DNA Synthesis Market is projected to grow at a 9.04% CAGR from 2025 to 2035, driven by advancements in biotechnology, personalized medicine, and synthetic biology applications.

    New opportunities lie in:

    • Develop customized DNA synthesis solutions for emerging biotech startups.
    • Invest in automation technologies to enhance production efficiency.
    • Expand service offerings in gene editing and synthetic biology collaborations.

    By 2035, the DNA Synthesis Market is expected to be robust, reflecting substantial growth and innovation.

    Market Segmentation

    DNA Synthesis Market End User Outlook

    • Academic Research Institutions
    • Pharmaceutical Companies
    • Biotechnology Companies
    • Clinical Laboratories

    DNA Synthesis Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    DNA Synthesis Market Technology Outlook

    • Solid-Phase Synthesis
    • Liquid-Phase Synthesis
    • PCR-Based Synthesis

    DNA Synthesis Market Application Outlook

    • Gene Therapy
    • Synthetic Biology
    • Molecular Diagnostics
    • Vaccine Development

    DNA Synthesis Market Product Type Outlook

    • Oligonucleotides
    • Gene Fragments
    • Gene Libraries

    Report Scope

    Report Attribute/Metric

    Details

    Market Size 2024

    4.63 (USD Billion)

    Market Size 2035

    28.22 (USD Billion)

    Compound Annual Growth Rate (CAGR)

    20.50% (2025 - 2035)

    Report Coverage

    Revenue Forecast, Competitive Landscape, Growth Factors, and Trends

    Base Year

    2024

    Market Forecast Period

    2025 - 2035

    Historical Data

    2019 - 2024

    Market Forecast Units

    USD Billion

    Key Companies Profiled

    DNA2.0, Genscript, Thermo Fisher Scientific, GeneArt, Agilent Technologies, Twist Bioscience, Tecan, BGI, Synthetic Genomics, Integrated DNA Technologies, Codexis, Eurofins Genomics, Sigena, Eurofins Scientific

    Segments Covered

    Application, Product Type, End User, Technology, Regional

    Key Market Opportunities

    Synthetic biology advancements, Personalized medicine growth, Biopharmaceuticals expansion, Agricultural biotechnology innovations, Genomic research funding increases

    Key Market Dynamics

    Technological advancements, Increasing research funding, Rising demand for synthetic biology, Growth in personalized medicine, Expanding application areas

    Countries Covered

    North America, Europe, APAC, South America, MEA

    Market Size 2025 4.37 (USD Billion)



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    FAQs

    What is the projected growth of the DNA synthesis market?

    The DNA synthesis market is the expected increase in total market value of 28.22 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the DNA synthesis market?

    DNA synthesis market size was valued at approximately 3.63 billion USD in 2024. This figure will reach 28.22 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the DNA synthesis market?

    DNA synthesis market is expected to grow at a CAGR of 20.5% between 2025 and 2035.

    How much will the DNA synthesis market be worth by 2035?

    DNA synthesis market is expected to be worth of 28.22 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the DNA synthesis market perform over the next 10 years?

    Over the next 10 years the DNA synthesis market is expected to shift from usd billion 3.63 to 28.22 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region is expected to have the largest market share in the DNA Synthesis Market by 2035?

    North America is expected to have the largest market share, valued at 5.0 USD Billion by 2035.

    What are the anticipated market sizes for key applications like Gene Therapy and Synthetic Biology in 2035?

    In 2035, Gene Therapy is anticipated to reach 3.0 USD Billion and Synthetic Biology is expected to be valued at 4.2 USD Billion.

    Which key players are leading the DNA Synthesis Market?

    Major players in the DNA Synthesis Market include DNA2.0, Genscript, Thermo Fisher Scientific, and Twist Bioscience, among others.

    How is the DNA Synthesis Market expected to grow in the Asia Pacific region by 2035?

    The Asia Pacific region is expected to grow to a market size of 2.5 USD Billion by 2035.

    What challenges and opportunities are anticipated in the DNA Synthesis Market?

    Challenges include regulatory hurdles while opportunities lie in expanding applications like vaccine development and synthetic biology.

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