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United States Photodynamic Therapy Market

ID: MRFR/Pharma/19151-HCR
128 Pages
Rahul Gotadki
October 2025

United States Photodynamic Therapy Market Size, Growth Research Report By Product Type (Photosensitizer Drugs and Photodynamic Therapy Devices), By Light Source (Lasers, Light Emitting Diodes (LEDs), Lamps, and Others), By Application (Cancer, Actinic Keratosis (AK), Psoriasis, Acne, and Others), By End User (Hospitals, Cancer Treatment Centers, Cosmetic and Dermatology Clinics, and Others), – Competitor Industry Analysis and Trends Forecast Till 2035

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United States Photodynamic Therapy Market Summary

As per analysis, the US Photodynamic Therapy Market is projected to grow from USD 320.4 Million in 2024 to USD 900.0 Million by 2035, exhibiting a compound annual growth rate (CAGR) of 9.84% during the forecast period (2025 - 2035).

Key Market Trends & Highlights

The US Photodynamic Therapy Market is poised for growth driven by technological advancements and increasing awareness.

  • The oncology segment remains the largest contributor to the market, reflecting a robust demand for effective cancer treatments.
  • The dermatology segment is currently the fastest-growing area, indicating a rising interest in non-invasive skin therapies.
  • Porphyrins dominate the market as the largest photodynamic agents, while phthalocyanines are emerging as the fastest-growing category.
  • Key market drivers include the rising incidence of skin cancer and advancements in photodynamic agents, which are shaping treatment options.

Market Size & Forecast

2024 Market Size 320.4 (USD Million)
2035 Market Size 900.0 (USD Million)
CAGR (2025 - 2035) 9.84%

Major Players

Photocure ASA (NO), Merck & Co., Inc. (US), Galderma S.A. (CH), Sensus Healthcare, Inc. (US), DUSA Pharmaceuticals, Inc. (US), Aduro Biotech, Inc. (US), Curelight Ltd. (IL), OncoSec Medical Incorporated (US)

United States Photodynamic Therapy Market Trends

The US Photodynamic Therapy Market is currently experiencing a notable evolution, driven by advancements in technology and an increasing understanding of the therapeutic potential of light-activated treatments. This market encompasses a range of applications, including oncology, dermatology, and ophthalmology, where photodynamic therapy is utilized to target specific cells while minimizing damage to surrounding tissues. The growing prevalence of skin cancers and other conditions that photodynamic therapy can address appears to be propelling interest among healthcare providers and patients alike. Furthermore, the integration of innovative light delivery systems and photosensitizers is likely enhancing treatment efficacy, thereby expanding the market's reach. In addition to technological advancements, regulatory support from government agencies is fostering a conducive environment for the US Photodynamic Therapy Market. The Food and Drug Administration has been actively approving new therapies and devices, which may encourage further research and development in this field. As awareness of photodynamic therapy continues to rise, educational initiatives aimed at both healthcare professionals and patients are expected to play a crucial role in driving adoption. Overall, the US Photodynamic Therapy Market seems poised for growth, with a focus on improving patient outcomes and expanding treatment options across various medical disciplines.

Technological Advancements

The US Photodynamic Therapy Market is witnessing rapid technological advancements that enhance treatment effectiveness. Innovations in light delivery systems and photosensitizers are improving the precision of therapies, allowing for targeted treatment of affected areas while preserving healthy tissue. This trend is likely to attract more healthcare providers to adopt photodynamic therapy as a viable treatment option.

Regulatory Support

Regulatory bodies in the United States are increasingly supportive of photodynamic therapy, facilitating the approval of new treatments and devices. This regulatory environment encourages research and development, which may lead to the introduction of novel therapies. As a result, the US Photodynamic Therapy Market is expected to benefit from a steady influx of innovative solutions.

Growing Awareness and Education

There is a rising awareness of photodynamic therapy among both healthcare professionals and patients in the United States. Educational initiatives aimed at informing stakeholders about the benefits and applications of this treatment are becoming more prevalent. This trend is likely to drive greater adoption of photodynamic therapy, as more individuals seek out effective treatment options for various conditions.

United States Photodynamic Therapy Market Drivers

Rising Incidence of Skin Cancer

The US Photodynamic Therapy Market is experiencing growth due to the increasing incidence of skin cancer, particularly melanoma. According to the American Cancer Society, skin cancer remains the most common form of cancer in the United States, with over 5 million cases treated annually. This alarming trend has prompted healthcare providers to seek effective treatment options, including photodynamic therapy, which offers a minimally invasive approach with fewer side effects compared to traditional methods. As awareness of skin cancer rises, patients are more likely to explore innovative treatments, thereby driving demand within the US Photodynamic Therapy Market. Furthermore, the potential for photodynamic therapy to be used in combination with other treatments may enhance its appeal, suggesting a promising future for this sector.

Advancements in Photodynamic Agents

Innovations in photodynamic agents are significantly influencing the US Photodynamic Therapy Market. Recent developments have led to the creation of more effective and targeted photosensitizers, which enhance the efficacy of photodynamic therapy. For instance, new agents are being designed to selectively accumulate in cancerous tissues, thereby minimizing damage to surrounding healthy cells. This advancement not only improves treatment outcomes but also reduces recovery times for patients. As a result, healthcare providers are increasingly adopting these advanced agents, contributing to the growth of the US Photodynamic Therapy Market. The ongoing research and development in this area indicate a strong potential for further enhancements, which could lead to broader applications of photodynamic therapy in various cancer types.

Regulatory Approvals and Guidelines

The US Photodynamic Therapy Market is positively impacted by regulatory approvals and guidelines that facilitate the adoption of photodynamic therapy. The US Food and Drug Administration (FDA) has approved several photodynamic agents and devices for clinical use, which has bolstered confidence among healthcare providers and patients alike. These approvals not only validate the safety and efficacy of photodynamic therapy but also encourage further research and development in the field. Additionally, the establishment of clinical guidelines by professional organizations promotes the standardization of treatment protocols, ensuring that patients receive optimal care. As regulatory support continues to evolve, it is expected that the US Photodynamic Therapy Market will expand, with more healthcare facilities integrating photodynamic therapy into their cancer treatment offerings.

Increased Investment in Cancer Treatment

The US Photodynamic Therapy Market is benefiting from increased investment in cancer treatment research and development. Government initiatives, such as the National Cancer Institute's funding programs, are aimed at fostering innovation in cancer therapies, including photodynamic therapy. This financial support encourages collaboration between academic institutions and industry players, leading to the development of novel treatment modalities. Moreover, venture capital investments in biotechnology firms focused on photodynamic therapy are on the rise, reflecting a growing confidence in the market's potential. As funding continues to flow into this sector, it is likely that advancements in photodynamic therapy will accelerate, further solidifying its position within the US Photodynamic Therapy Market.

Growing Demand for Minimally Invasive Procedures

The US Photodynamic Therapy Market is witnessing a surge in demand for minimally invasive procedures, driven by patient preferences for less traumatic treatment options. Photodynamic therapy, which utilizes light to activate photosensitizing agents, offers a non-surgical alternative for treating various cancers, particularly skin and superficial tumors. Patients are increasingly seeking therapies that promise quicker recovery times and reduced pain, making photodynamic therapy an attractive option. This shift in patient expectations is prompting healthcare providers to incorporate photodynamic therapy into their treatment protocols, thereby expanding its presence in the US Photodynamic Therapy Market. As the trend towards minimally invasive treatments continues, the market is likely to experience sustained growth.

Market Segment Insights

By Application: Oncology (Largest) vs. Dermatology (Fastest-Growing)

In the US Photodynamic Therapy Market, the application segments showcase a diverse distribution with oncology leading prominently. Oncology is recognized for its significant share due to the increasing prevalence of cancer, which drives demand for innovative treatment options. Following closely, dermatology is experiencing rapid growth, fueled by the rising incidence of skin disorders and the growing awareness of photodynamic therapy benefits. This distinction indicates a strong adoption of these therapies among healthcare providers and patients alike, especially in detecting and treating cancerous cells. The growth trends within these segments are influenced by technological advancements and increased research funding dedicated to photodynamic therapy's efficacy. Additionally, favorable regulatory frameworks and heightened patient acceptance further bolster these applications. As oncology remains the most substantial segment, dermatology's swift ascent highlights the shift towards non-invasive treatments, potentially reshaping the therapeutic landscape over the coming years.

Oncology (Dominant) vs. Dermatology (Emerging)

Oncology remains the dominant application in the US Photodynamic Therapy Market, characterized by its strong focus on treating various types of cancer, including skin, lung, and esophageal cancers. This dominance is attributed to the therapy's ability to selectively target cancer cells while minimizing damage to surrounding healthy tissue. The emergence of dermatology as a key player showcases the market's evolution, with increasing emphasis on treating skin lesions, acne, and psoriasis. The rapid adoption of photodynamic therapy in this field is further supported by advancements in laser technology and a growing preference for minimally invasive procedures among patients. Together, these segments illustrate the shifting dynamics and expanding opportunities within the Photodynamic Therapy landscape.

By Type of Photosensitizer: Porphyrins (Largest) vs. Phthalocyanines (Fastest-Growing)

Within the US Photodynamic Therapy Market, the distribution of market share among various types of photosensitizers reveals a clear hierarchy. Porphyrins remain the largest segment, driven by their extensive historical use and proven efficacy in clinical applications. Phthalocyanines, while not the largest current segment, are rapidly gaining traction due to their enhanced absorption characteristics and versatility in treatment applications. This dynamic landscape indicates a robust competitive environment among these leading photosensitizer types. As the market evolves, growth trends are notably influenced by ongoing research and development in photosensitizer formulations. Increased awareness and adaptability of treatment approaches, particularly in cancer therapies, are propelling Phthalocyanines into the forefront as the fastest-growing segment. Additionally, the rising demand for personalized medicine and combination therapies is further supporting the introduction and acceptance of new photosensitizer options, augmenting the therapeutic capabilities of Photodynamic Therapy across various medical specializations.

Porphyrins (Dominant) vs. Phthalocyanines (Emerging)

Porphyrins have established themselves as the dominant type of photosensitizer in the US Photodynamic Therapy Market, primarily attributed to their long-standing use and clinical validation. These compounds demonstrate excellent light-absorbing properties and a favorable profile for use in a variety of cancers, making them the preferred choice for many healthcare providers. Conversely, Phthalocyanines are emerging as a competitive alternative, noted for their superior stability and potential in treating a broader spectrum of diseases. Their advanced photophysical properties allow for deeper tissue penetration and improved therapeutic outcomes, thus capturing the attention of researchers and clinicians alike. As innovation continues in this space, Phthalocyanines are expected to gain a larger share, creating opportunities for novel applications in photodynamic therapy.

By End User: Hospitals (Largest) vs. Ambulatory Surgical Centers (Fastest-Growing)

In the US Photodynamic Therapy Market, hospitals hold the largest share of end users due to their extensive resources and specialized personnel. They provide a wide range of services, incorporating advanced photodynamic therapy technologies in treating various conditions, including cancer and dermatological disorders. Ambulatory surgical centers, while smaller in share, are rapidly gaining traction as they offer cost-effective and convenient treatment options which appeal to patients requiring outpatient services. As the demand for minimally invasive procedures grows, the role of ambulatory surgical centers as a fast-growing segment is becoming more pronounced. These centers benefit from increased patient preference for outpatient care, advancements in photodynamic therapy techniques, and favorable reimbursement policies. This trend is expected to drive significant growth in this segment, allowing it to potentially equalize the market share with hospitals in the foreseeable future.

Hospitals (Dominant) vs. Dermatology Clinics (Emerging)

Hospitals are positioned as the dominant end user in the US Photodynamic Therapy Market, primarily due to their comprehensive treatment capabilities and access to a broad range of photodynamic therapy technologies. They typically offer extensive resources, including multidisciplinary teams that enhance patient care and treatment outcomes. Dermatology clinics, while emerging, have carved out a niche by specializing in skin-related conditions and leveraging targeted photodynamic therapies for issues such as acne, psoriasis, and precancerous lesions. Their growth is fueled by increasing awareness of skin health and advancements in technology that streamline treatment processes, attracting patients seeking specialized care. As the market evolves, these clinics are likely to expand their offerings and further establish their position in the therapy landscape.

Get more detailed insights about United States Photodynamic Therapy Market

Regional Insights

North America : Leading Market for Innovation

The North American market for photodynamic therapy (PDT) is primarily driven by increasing incidences of skin cancer and other dermatological conditions. The U.S. holds the largest share of the market, accounting for approximately 70%, followed by Canada with around 15%. Regulatory support from the FDA for PDT products has further catalyzed market growth, enhancing patient access to innovative treatments. The rising awareness of PDT's benefits among healthcare providers and patients is also a significant growth driver. In this region, the competitive landscape is characterized by the presence of key players such as DUSA Pharmaceuticals Inc, Merck & Co Inc, and Hologic Inc. These companies are actively involved in research and development to enhance PDT technologies. The U.S. market is also witnessing collaborations between pharmaceutical companies and research institutions, aimed at improving treatment efficacy and expanding applications of PDT. This dynamic environment positions North America as a leader in The United States Photodynamic Therapy Market.

Europe : Emerging Market with Potential

Europe is witnessing a growing interest in photodynamic therapy, driven by increasing healthcare expenditure and advancements in medical technologies. The region is characterized by a diverse regulatory landscape, with countries like Germany and the UK leading the market. Germany holds approximately 25% of the European market share, while the UK follows closely with around 20%. The European Medicines Agency (EMA) has been instrumental in approving new PDT products, which has spurred market growth and innovation in treatment options. Leading countries in Europe are focusing on enhancing their healthcare infrastructure to support the adoption of PDT. The competitive landscape includes key players such as Galderma S.A. and Photocure ASA, which are investing in clinical trials to expand the applications of PDT. Additionally, partnerships between healthcare providers and pharmaceutical companies are fostering innovation, making Europe a promising market for photodynamic therapy in the coming years.

Asia-Pacific : Rapidly Growing Market

The Asia-Pacific region is rapidly emerging as a significant market for photodynamic therapy, driven by rising healthcare awareness and increasing incidences of skin diseases. Countries like Japan and Australia are leading the market, with Japan holding approximately 30% of the regional share, followed by Australia at around 20%. The regulatory environment is becoming more favorable, with governments promoting advanced treatment options, which is expected to further boost market growth in the coming years. The competitive landscape in Asia-Pacific is evolving, with local and international players entering the market. Companies such as Sientra Inc and Aclaris Therapeutics Inc are expanding their presence in this region. The focus on research and development is increasing, with many firms investing in innovative PDT technologies to cater to the growing demand. This trend is expected to create numerous opportunities for growth and collaboration in the Asia-Pacific PDT market.

Middle East and Africa : Untapped Market Potential

The Middle East and Africa region presents untapped potential for photodynamic therapy, driven by increasing healthcare investments and a growing awareness of advanced treatment options. Countries like South Africa and the UAE are at the forefront, with South Africa holding approximately 15% of the regional market share. The regulatory landscape is gradually improving, with local health authorities beginning to recognize the benefits of PDT, which is expected to catalyze market growth in the near future. The competitive landscape is still developing, with a few key players like Bausch Health Companies Inc and Curelight Ltd making strides in the region. The focus on enhancing healthcare infrastructure and increasing access to innovative treatments is crucial for market expansion. As awareness of PDT grows, more healthcare providers are likely to adopt these therapies, paving the way for future growth in the Middle East and Africa.

United States Photodynamic Therapy Market Regional Image

Key Players and Competitive Insights

The Photodynamic Therapy Market is currently characterized by a dynamic competitive landscape, driven by advancements in technology and increasing demand for minimally invasive treatment options. Key players such as Merck & Co., Inc. (US), DUSA Pharmaceuticals, Inc. (US), and OncoSec Medical Incorporated (US) are actively shaping the market through strategic initiatives. Merck & Co. (US) has positioned itself as a leader in innovation, focusing on the development of novel photodynamic agents that enhance treatment efficacy. Meanwhile, DUSA Pharmaceuticals, Inc. (US) emphasizes regional expansion and partnerships to broaden its market reach, particularly in dermatological applications. OncoSec Medical Incorporated (US) is leveraging digital transformation to optimize its clinical trials and patient engagement strategies, thereby enhancing its competitive edge.

The business tactics employed by these companies reflect a concerted effort to localize manufacturing and optimize supply chains, which are crucial in a moderately fragmented market. This competitive structure allows for a diverse range of products and services, fostering innovation while also presenting challenges in terms of market share and customer loyalty. The collective influence of these key players is significant, as they navigate regulatory landscapes and adapt to evolving consumer preferences.

In December 2025, Merck & Co., Inc. (US) announced a collaboration with a leading research institution to develop a next-generation photodynamic therapy platform aimed at treating various cancers. This strategic move is likely to enhance Merck's portfolio and solidify its position as a frontrunner in the market, as it seeks to integrate cutting-edge research with practical applications in oncology.

In November 2025, DUSA Pharmaceuticals, Inc. (US) launched a new photodynamic therapy device specifically designed for the treatment of actinic keratosis. This product introduction not only expands DUSA's product line but also demonstrates its commitment to addressing unmet medical needs in dermatology. The launch is expected to drive revenue growth and strengthen DUSA's market presence.

In October 2025, OncoSec Medical Incorporated (US) reported a successful Phase 2 clinical trial for its photodynamic therapy treatment in combination with immunotherapy for melanoma patients. This achievement underscores the potential of combining therapies to enhance patient outcomes, positioning OncoSec as a key player in the evolving landscape of cancer treatment.

As of January 2026, the competitive trends in the Photodynamic Therapy Market are increasingly influenced by digitalization, sustainability, and the integration of artificial intelligence (AI) in treatment protocols. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in driving innovation and improving patient care. Looking ahead, the competitive differentiation in this market is likely to shift from price-based competition to a focus on technological advancements, innovative treatment solutions, and reliable supply chains, reflecting a broader trend towards value-based healthcare.

Key Companies in the United States Photodynamic Therapy Market include

Industry Developments

January 2023:The international biopharmaceutical company Biofrontera AG announced that the U.S. Patent Office (USPTO) had sent a notice of allowance for the application "Photodynamic therapy comprising two light exposures at different wavelengths" (US Appl. No. 17/269,816) to its wholly owned subsidiary Biofrontera Bioscience GmbH. This patent covers several inventions related to a novel lighting technique for Photodynamic Therapy (PDT) treatment of dermatological skin disorders.

March 2022:The US patent No. 11,235,169 for the BF-RhodoLED XL illumination device was previously issued to Biofrontera Inc. The company has announced that the device is now listed in the FDA publication "Approved Drug Products with Therapeutic Equivalency Evaluations, or the Orange Book.

Future Outlook

United States Photodynamic Therapy Market Future Outlook

The US Photodynamic Therapy Market is projected to grow at a 9.84% CAGR from 2025 to 2035, driven by technological advancements, increasing cancer prevalence, and rising awareness of minimally invasive treatments.

New opportunities lie in:

  • Development of targeted photodynamic agents for specific cancer types.
  • Expansion of telemedicine platforms for remote photodynamic therapy consultations.
  • Partnerships with healthcare providers for integrated photodynamic therapy services.

By 2035, the market is expected to achieve substantial growth, positioning itself as a leader in innovative cancer treatment solutions.

Market Segmentation

United States Photodynamic Therapy Market End User Outlook

  • Hospitals
  • Ambulatory Surgical Centers
  • Dermatology Clinics
  • Dental Clinics

United States Photodynamic Therapy Market Application Outlook

  • Oncology
  • Dermatology
  • Cardiology
  • Dentistry

United States Photodynamic Therapy Market Type of Photosensitizer Outlook

  • Porphyrins
  • Phthalocyanines
  • Bacteriochlorophylls
  • Synthetic Dyes

Report Scope

MARKET SIZE 2024320.4(USD Million)
MARKET SIZE 2025355.32(USD Million)
MARKET SIZE 2035900.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)9.84% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies ProfiledPhotocure ASA (NO), Merck & Co., Inc. (US), Galderma S.A. (CH), Sensus Healthcare, Inc. (US), DUSA Pharmaceuticals, Inc. (US), Aduro Biotech, Inc. (US), Curelight Ltd. (IL), OncoSec Medical Incorporated (US)
Segments CoveredApplication, Type of Photosensitizer, End User
Key Market OpportunitiesAdvancements in light-activated drugs enhance treatment efficacy in the US Photodynamic Therapy Market.
Key Market DynamicsGrowing regulatory support and technological advancements drive the expansion of the US Photodynamic Therapy Market.
Countries CoveredUS
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FAQs

What is the current valuation of the US Photodynamic Therapy Market?

As of 2024, the US Photodynamic Therapy Market was valued at 320.4 USD Million.

What is the projected market size for the US Photodynamic Therapy Market by 2035?

The market is projected to reach 900.0 USD Million by 2035.

What is the expected CAGR for the US Photodynamic Therapy Market during the forecast period 2025 - 2035?

The expected CAGR for the market during the forecast period 2025 - 2035 is 9.84%.

Which application segment is anticipated to dominate the US Photodynamic Therapy Market?

The Oncology segment is expected to dominate, with a valuation projected to grow from 128.0 USD Million to 360.0 USD Million.

How does the Dermatology segment perform in the US Photodynamic Therapy Market?

The Dermatology segment was valued at 80.0 USD Million in 2024 and is projected to reach 220.0 USD Million by 2035.

What types of photosensitizers are utilized in the US Photodynamic Therapy Market?

Key types of photosensitizers include Porphyrins, Phthalocyanines, Bacteriochlorophylls, and Synthetic Dyes, with Synthetic Dyes projected to grow from 120.4 USD Million to 330.0 USD Million.

Which end-user segment is expected to show significant growth in the US Photodynamic Therapy Market?

Hospitals are anticipated to show significant growth, with a valuation expected to rise from 128.16 USD Million to 360.0 USD Million.

Who are the key players in the US Photodynamic Therapy Market?

Key players include Photocure ASA, Merck & Co., Inc., Galderma S.A., and Sensus Healthcare, Inc.

What is the projected growth for the Cardiology segment in the US Photodynamic Therapy Market?

The Cardiology segment is projected to grow from 60.0 USD Million to 180.0 USD Million by 2035.

How does the market for Dental Clinics compare to other end-user segments?

The Dental Clinics segment is expected to grow from 64.08 USD Million to 180.0 USD Million, indicating a competitive position among end-user segments.

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