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South America Anti VEGF Market

ID: MRFR/HC/50413-HCR
200 Pages
Garvit Vyas
October 2025

South America Anti-VEGF Market Research Report By Product (Eylea, Lucentis, Beovu), By Disease (Macular Edema, Diabetic Retinopathy, Retinal Vein Occlusion, Age-Related Macular Degeneration) and By Region (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035

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South America Anti VEGF Market Summary

As per MRFR analysis, the South America anti-VEGF market size was estimated at 1818.88 USD Million in 2024. The South America anti vegf market is projected to grow from 1842.71 USD Million in 2025 to 2100.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 1.31% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America anti-VEGF market is poised for growth driven by increasing healthcare access and rising incidences of retinal diseases.

  • The South America anti-VEGF market is experiencing a notable upward trajectory due to the rising incidence of retinal diseases.
  • Brazil remains the largest market for anti-VEGF treatments, while Mexico is recognized as the fastest-growing region in this sector.
  • Advancements in treatment options are enhancing patient outcomes and expanding the market's potential.
  • Key market drivers include the increasing prevalence of diabetic retinopathy and government initiatives for eye health, which are likely to bolster market growth.

Market Size & Forecast

2024 Market Size 1818.88 (USD Million)
2035 Market Size 2100.0 (USD Million)
CAGR (2025 - 2035) 1.31%

Major Players

Regeneron Pharmaceuticals (US), Roche Holding (CH), Novartis (CH), Bayer AG (DE), Pfizer Inc. (US), Amgen Inc. (US), Santen Pharmaceutical (JP), Eli Lilly and Company (US), Hikma Pharmaceuticals (GB)

South America Anti VEGF Market Trends

The anti vegf market is currently experiencing notable growth in South America, driven by an increasing prevalence of retinal diseases and age-related macular degeneration. The region's healthcare infrastructure is gradually improving, which facilitates better access to innovative therapies. Furthermore, the rising awareness among healthcare professionals and patients regarding the benefits of anti-VEGF treatments is contributing to market expansion. This trend is likely to continue as more effective therapies are developed and introduced into the market, potentially enhancing patient outcomes. In addition, the regulatory environment in South America appears to be evolving, with governments focusing on improving drug approval processes. This may lead to a quicker introduction of new anti-VEGF therapies, thereby stimulating competition among pharmaceutical companies. The collaboration between local and international firms is also becoming more prevalent, which could enhance research and development efforts. Overall, the anti vegf market in South America seems poised for sustained growth, driven by both demand and innovation in treatment options.

Rising Incidence of Retinal Diseases

The increasing occurrence of retinal diseases in South America is a primary driver for the anti vegf market. As the population ages, conditions such as diabetic retinopathy and macular degeneration are becoming more common, necessitating effective treatment options. This trend indicates a growing need for anti-VEGF therapies to manage these conditions.

Advancements in Treatment Options

Innovations in anti-VEGF therapies are emerging, with new formulations and delivery methods being developed. These advancements may enhance the efficacy and safety profiles of existing treatments, potentially leading to increased adoption among healthcare providers in South America. This trend suggests a shift towards more personalized treatment approaches.

Improved Healthcare Access

The enhancement of healthcare infrastructure in South America is facilitating better access to anti-VEGF treatments. As healthcare systems improve, more patients are likely to receive timely diagnoses and treatments, which could drive market growth. This trend highlights the importance of healthcare policy in shaping treatment accessibility.

South America Anti VEGF Market Drivers

Rising Geriatric Population

The increasing geriatric population in South America is a notable driver for the anti vegf market. As individuals age, the risk of developing age-related macular degeneration and other retinal diseases escalates. Current estimates suggest that by 2030, the population aged 65 and older in South America will exceed 100 million. This demographic shift is likely to result in a higher incidence of retinal diseases, thereby increasing the demand for anti-VEGF therapies. The anti vegf market must adapt to this growing need by ensuring the availability of effective treatment options tailored to the elderly, thus fostering market expansion.

Government Initiatives for Eye Health

Government initiatives aimed at improving eye health in South America are expected to bolster the anti vegf market. Various health ministries are implementing programs to raise awareness about retinal diseases and promote early diagnosis and treatment. These initiatives often include funding for public health campaigns and subsidized access to medications, including anti-VEGF therapies. For instance, some countries have allocated budgets exceeding $10 million annually to combat vision impairment caused by retinal diseases. Such efforts not only enhance patient access to necessary treatments but also encourage healthcare providers to adopt anti-VEGF therapies as standard care, thus driving market growth.

Technological Advancements in Drug Delivery

Technological advancements in drug delivery systems are poised to transform the anti vegf market in South America. Innovations such as sustained-release formulations and targeted delivery mechanisms are enhancing the efficacy of anti-VEGF therapies. These advancements may lead to improved patient compliance and reduced treatment frequency, which is particularly beneficial in regions with limited healthcare access. The market for anti-VEGF treatments is projected to grow by approximately 15% annually, driven by these technological improvements. As healthcare providers increasingly adopt these advanced delivery systems, the anti vegf market is likely to experience significant growth, catering to the evolving needs of patients.

Increasing Prevalence of Diabetic Retinopathy

The rising prevalence of diabetic retinopathy in South America is a critical driver for the anti vegf market. As diabetes rates continue to escalate, the number of individuals affected by this sight-threatening condition is projected to increase significantly. Reports indicate that approximately 30% of diabetic patients may develop diabetic retinopathy, leading to a growing demand for effective treatment options. The anti vegf market is likely to benefit from this trend, as anti-VEGF therapies have shown efficacy in managing the progression of the disease. Furthermore, the increasing awareness of diabetic complications among healthcare providers and patients may further stimulate the demand for anti-VEGF treatments, thereby enhancing market growth in the region.

Rising Investment in Healthcare Infrastructure

Rising investment in healthcare infrastructure across South America is expected to positively impact the anti vegf market. Governments and private entities are increasingly allocating funds to enhance healthcare facilities, improve diagnostic capabilities, and expand access to advanced treatments. For instance, several countries have reported investments exceeding $5 billion in healthcare infrastructure over the past few years. This influx of capital is likely to facilitate the adoption of anti-VEGF therapies, as healthcare providers gain access to better resources and training. Consequently, the anti vegf market is anticipated to grow as healthcare systems become more equipped to manage retinal diseases effectively.

Market Segment Insights

By Product: Eylea (Largest) vs. Beovu (Fastest-Growing)

The anti VEGF market is characterized by a competitive landscape with leading products like Eylea, Lucentis, and Beovu. Eylea holds a substantial share, reflecting its established presence and physician preference. Lucentis, while still significant, has faced challenges as newer therapies emerge. Beovu, although currently smaller in terms of market share, is rapidly gaining traction due to its innovative formulation and favorable dosing schedule. Growth in this segment is driven by increasing prevalence of age-related macular degeneration and diabetic retinopathy, leading to higher demand for anti VEGF therapies. The rise in diabetes rates and an aging population contribute to this trend. Furthermore, advancements in product formulations, including improved administration methods, are expected to enhance patient adherence and encourage the uptake of newer therapies like Beovu, positioning it as a key player in the future.

Eylea (Dominant) vs. Beovu (Emerging)

Eylea has established itself as the dominant player in the market due to its comprehensive efficacy and safety profile, leading to widespread acceptance by healthcare professionals. Its extended dosing interval has garnered loyalty among patients, contributing to its sustained popularity. In contrast, Beovu is emerging as a significant contender, appealing to both patients and physicians with its novel formulation that allows for less frequent dosing. This characteristic addresses a crucial need for improved convenience, making Beovu attractive in the treatment landscape. As awareness of Beovu's benefits grows and clinical experience increases, its market share is expected to expand rapidly, positioning it as a key product in future treatment regimens.

By Disease: Macular Edema (Largest) vs. Diabetic Retinopathy (Fastest-Growing)

In the South America anti vegf market, Macular Edema holds the largest share, significantly dominating the landscape due to its high prevalence among patients suffering from diabetes and other ocular conditions. Diabetic Retinopathy, while not the largest, is gaining traction rapidly as awareness and screening initiatives expand, thus contributing to its share in the market. The competition among various anti-VEGF therapies further enhances the market dynamics within these segments. Growth in the South America anti vegf market is driven by a rise in ocular diseases as the population ages and diabetes cases increase. Innovations in treatment protocols and a shift towards early interventions are propelling the market forward. Additionally, the accessibility of advanced therapies is expected to bolster the growth of Diabetic Retinopathy, making it an area to watch closely as healthcare systems evolve in the region.

Macular Edema: Dominant vs. Diabetic Retinopathy: Emerging

Macular Edema represents the dominant segment in the South America anti vegf market due to its critical implications in vision loss, attracting substantial investment from pharmaceutical companies. This segment benefits from a well-established treatment framework and extensive clinical data supporting its therapies. On the other hand, Diabetic Retinopathy is emerging as a key segment, fueled by increasing incidences among diabetic populations and ongoing research into novel treatment options. This segment is characterized by a growing number of healthcare initiatives aimed at improving awareness and access to treatments, ultimately positioning it for significant growth in the coming years.

Get more detailed insights about South America Anti VEGF Market

Regional Insights

Brazil : Leading Market with Robust Growth

Brazil holds a commanding market share of 50.5% in the South American anti-VEGF market, valued at $850.0 million. Key growth drivers include increasing prevalence of retinal diseases and government initiatives promoting healthcare access. The demand for innovative therapies is rising, supported by favorable regulatory policies that streamline drug approvals. Infrastructure improvements in healthcare facilities further bolster market growth, enhancing patient access to treatments.

Mexico : Growth Driven by Healthcare Reforms

Mexico accounts for 18.5% of the South American anti-VEGF market, valued at $300.0 million. The market is driven by healthcare reforms aimed at improving access to treatments and increasing awareness of retinal diseases. Demand is growing in urban areas, particularly in Mexico City and Guadalajara, where healthcare infrastructure is being enhanced. Regulatory support for innovative therapies is also a key factor, fostering a competitive environment for major players.

Argentina : Strong Demand Amid Economic Challenges

Argentina represents 25.5% of the South American anti-VEGF market, valued at $400.0 million. The market is driven by rising incidences of age-related macular degeneration and diabetic retinopathy. Government initiatives to improve healthcare access and affordability are crucial, despite economic challenges. The competitive landscape includes significant players like Novartis and Roche, with Buenos Aires being a key market due to its advanced healthcare facilities and patient population.

Rest of South America : Diverse Opportunities Across Regions

The Rest of South America holds a market share of 16.0%, valued at $268.88 million. This sub-region includes countries like Chile, Colombia, and Peru, where demand for anti-VEGF therapies is growing due to increasing awareness and healthcare improvements. Local regulations are evolving to support innovative treatments, creating a favorable business environment. Key players like Bayer and Amgen are expanding their presence, focusing on regional healthcare needs and partnerships.

South America Anti VEGF Market Regional Image

Key Players and Competitive Insights

The anti-VEGF market in South America is characterized by a dynamic competitive landscape, driven by increasing prevalence of retinal diseases and a growing aging population. Key players such as Regeneron Pharmaceuticals (US), Roche Holding (CH), and Novartis (CH) are strategically positioned to leverage innovation and regional expansion. Regeneron Pharmaceuticals (US) focuses on enhancing its product portfolio through continuous research and development, while Roche Holding (CH) emphasizes partnerships to bolster its market presence. Novartis (CH) is actively pursuing mergers and acquisitions to consolidate its position, indicating a trend towards a more concentrated market structure.

The market appears moderately fragmented, with several players vying for dominance. Companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. This strategic focus on operational excellence is likely to influence competitive dynamics, as firms seek to differentiate themselves through superior service delivery and product availability.

In October 2025, Regeneron Pharmaceuticals (US) announced a collaboration with a local biotech firm to develop a novel delivery system for its anti-VEGF therapies. This strategic move is expected to enhance patient access and streamline distribution channels, thereby reinforcing Regeneron’s competitive edge in the region. Such partnerships may also facilitate quicker adaptation to local market needs, which is crucial in a diverse landscape like South America.

In September 2025, Roche Holding (CH) launched a new digital platform aimed at improving patient engagement and adherence to anti-VEGF treatments. This initiative reflects a growing trend towards digitalization in healthcare, suggesting that Roche is keen on integrating technology to enhance patient outcomes. By leveraging data analytics, the company may gain insights into treatment efficacy and patient behavior, potentially leading to improved product offerings.

In August 2025, Novartis (CH) completed the acquisition of a smaller firm specializing in innovative drug delivery systems. This acquisition is likely to bolster Novartis’s capabilities in the anti-VEGF segment, allowing for the development of more effective therapies. The strategic importance of this move lies in its potential to enhance Novartis’s competitive positioning by expanding its product pipeline and addressing unmet medical needs in the region.

As of November 2025, the competitive trends in the anti-VEGF market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in navigating complex market dynamics. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition towards innovation, technology, and supply chain reliability. This transition may ultimately reshape the landscape, fostering a more sustainable and patient-centric approach in the anti-VEGF market.

Key Companies in the South America Anti VEGF Market market include

Industry Developments

The South America Anti-VEGF Market has recently seen significant developments, with companies like Novartis and Regeneron Pharmaceuticals actively expanding their market presence. In March 2023, Novartis unveiled robust results from clinical trials supporting the efficacy of their anti-VEGF treatments, which are expected to bolster their share in the region. On the competitive front, Alliances between Hikma Pharmaceuticals and local biotech firms have fostered advancements in product distribution, with multiple launches projected for the coming year.In terms of market dynamics, the growing prevalence of retinal diseases in South America is driving a surge in demand for anti-VEGF therapies.

As of October 2023, Amgen and Pfizer reported significant growth in their market valuation as a result of increased investments in Research and Development and expanded access programs, positively impacting overall market health. The health authorities are also ramping up efforts to ensure better accessibility to anti-VEGF treatments, acknowledging the rising disease burden.No recent mergers or acquisitions involving the specified companies have been publicly disclosed in this sector. However, Santen Pharmaceutical's strategic partnerships with regional players hint at potential future consolidations.

Future Outlook

South America Anti VEGF Market Future Outlook

The Anti VEGF Market is projected to grow at 1.31% CAGR from 2024 to 2035, driven by increasing prevalence of retinal diseases and advancements in treatment options.

New opportunities lie in:

  • Development of biosimilars to enhance market access and affordability.
  • Expansion of telemedicine platforms for remote patient monitoring and consultations.
  • Strategic partnerships with local healthcare providers to improve distribution channels.

By 2035, the anti-VEGF market is expected to solidify its position, driven by innovation and strategic collaborations.

Market Segmentation

South America Anti VEGF Market Disease Outlook

  • Macular Edema
  • Diabetic Retinopathy
  • Retinal Vein Occlusion
  • Age-Related Macular Degeneration

South America Anti VEGF Market Product Outlook

  • Eylea
  • Lucentis
  • Beovu

Report Scope

MARKET SIZE 20241818.88(USD Million)
MARKET SIZE 20251842.71(USD Million)
MARKET SIZE 20352100.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)1.31% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Regeneron Pharmaceuticals (US)", "Roche Holding (CH)", "Novartis (CH)", "Bayer AG (DE)", "Pfizer Inc. (US)", "Amgen Inc. (US)", "Santen Pharmaceutical (JP)", "Eli Lilly and Company (US)", "Hikma Pharmaceuticals (GB)"]
Segments CoveredProduct, Disease
Key Market OpportunitiesEmerging biologics and personalized therapies drive growth in the anti vegf market.
Key Market DynamicsRising demand for innovative anti-VEGF therapies driven by increasing prevalence of retinal diseases in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Anti-VEGF Market in 2024?

The South America Anti-VEGF Market is expected to be valued at 1.3 billion USD in 2024.

What will be the market value of the South America Anti-VEGF Market by 2035?

By 2035, the market value of the South America Anti-VEGF Market is anticipated to reach 2.07 billion USD.

What is the projected CAGR for the South America Anti-VEGF Market from 2025 to 2035?

The expected compound annual growth rate (CAGR) for the South America Anti-VEGF Market from 2025 to 2035 is 4.313%.

Which region holds the largest market share within the South America Anti-VEGF Market?

Brazil is expected to hold the largest market share, valued at approximately 0.52 billion USD in 2024.

What market size is forecasted for Eylea by 2035 in the South America Anti-VEGF Market?

Eylea is projected to reach a market value of 0.88 billion USD by 2035 in the South America Anti-VEGF Market.

Which key players are dominating the South America Anti-VEGF Market?

Major players include Novartis, Amgen, and Regeneron Pharmaceuticals, among others.

What is the expected growth rate for the Anti-VEGF Market in Mexico from 2024 to 2035?

The market size for Mexico is expected to grow from 0.34 billion USD in 2024 to 0.52 billion USD by 2035.

What is the projected market value of Lucentis in the South America Anti-VEGF Market by 2035?

The market value of Lucentis is forecasted to be 0.67 billion USD in 2035.

What are the growth drivers for the South America Anti-VEGF Market?

Growth drivers include increasing prevalence of retinal diseases and advancements in therapeutic options.

What will be the market value for Beovu by 2035 in the South America Anti-VEGF Market?

Beovu is expected to reach a market value of 0.52 billion USD by 2035 in the South America Anti-VEGF Market.

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