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    Short Read Sequencing Market

    ID: MRFR/HC/20278-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Short Read Sequencing Market Research Report By Application (Clinical diagnostics, Agrigenomics, Oncology, Genomics Research, Molecular Biology), By Technology (Illumina sequencing, Ion Torrent sequencing, SOLiD sequencing, SMRT sequencing), By End Use (Academic research institutes, Pharmaceutical companies, Biotechnology companies, Hospitals and clinics), By Product Type (Sequencing kits, Sequencing services, Sequencing instruments) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Short Read Sequencing Market Infographic
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    Short Read Sequencing Market Summary

    The Global Short Read Sequencing Market is projected to grow from 9.49 USD Billion in 2024 to 65.49 USD Billion by 2035.

    Key Market Trends & Highlights

    Short Read Sequencing Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 9.05% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 20 USD Billion, indicating robust growth.
    • in 2024, the market is valued at 9.49 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of short read sequencing due to advancements in genomic research is a major market driver.

    Market Size & Forecast

    2024 Market Size 9.49 (USD Billion)
    2035 Market Size 65.49 (USD Billion)
    CAGR (2025-2035) 19.20%

    Major Players

    Applied Biosystems, Element Biosciences, Thermo Fisher Scientific, PerkinElmer, Agilent Technologies, BGI, Qiagen, Illumina, 10x Genomics, BioRad Laboratories

    Short Read Sequencing Market Trends

    The Short Read Sequencing Market is growing quickly because genomic technologies are becoming better and more uses are being found in personalized medicine, cancer research, and infectious disease research. The falling cost of sequencing technologies is a major factor driving the market. This makes them easier for research institutes and healthcare providers to acquire. Also, the desire for precision medicine is speeding up the use of short-read sequencing since it lets researchers execute genome-wide investigations faster and more accurately. There are several possibilities to look into, such as using artificial intelligence and machine learning in data analysis.

    This might make sequencing findings easier to understand and more useful, which could lead to new ways to improve clinical diagnosis and treatment plans.

    Recent developments in the worldwide market show that there is a rise in partnerships between the public and commercial sectors to improve sequencing technology and its uses. Many governments are working to promote genomics research and make it easier for institutions to share more data. This is leading to greater innovation and faster results in genomic investigations. 

    The development of genomic data creation has also led to a rise in demand for sequencers that can handle massive amounts of data. Also, the emphasis on non-invasive diagnostic procedures is making people increasingly interested in liquid biopsies, which use short-read sequencing to find changes in the DNA of circulating tumors.

     Overall, these new developments will help the Global short-read sequencing Market thrive. Researchers will keep putting money into it, and it will keep growing as they look for new ways to study genetics.

    The Global Short Read Sequencing Market is poised for robust growth, driven by advancements in genomic technologies and increasing applications in personalized medicine.

    National Institutes of Health (NIH)

    Short Read Sequencing Market Drivers

    Market Growth Projections

    The Global Short Read Sequencing Market Industry is projected to experience substantial growth over the coming years. With a market value of 7.71 USD Billion in 2024, the industry is on track to reach 20 USD Billion by 2035. This growth is underpinned by a compound annual growth rate of 9.05% from 2025 to 2035, indicating a robust expansion driven by technological advancements, increasing demand for genomic research, and rising applications in personalized medicine. The market dynamics suggest a favorable environment for stakeholders, including researchers, healthcare providers, and technology developers, as they navigate the evolving landscape of genomic sequencing.

    Government Initiatives and Funding

    Government initiatives and funding play a crucial role in shaping the Global Short Read Sequencing Market Industry. Various countries are launching programs aimed at enhancing genomic research capabilities and infrastructure. For example, the National Institutes of Health in the United States has allocated substantial funding for genomics research, fostering innovation and collaboration among researchers. Such initiatives not only promote the development of new sequencing technologies but also encourage public-private partnerships that drive market growth. As governments recognize the importance of genomics in addressing public health challenges, the market is poised for sustained growth, reflecting the increasing investment in this sector.

    Increasing Demand for Genomic Research

    The Global Short Read Sequencing Market Industry experiences a surge in demand driven by the increasing focus on genomic research. Governments and research institutions globally are investing heavily in genomics to understand genetic disorders and develop targeted therapies. For instance, initiatives like the Human Genome Project have paved the way for extensive research in genomics, leading to breakthroughs in disease prevention and treatment. This growing interest is expected to contribute to the market's expansion, with projections indicating a growth to 20 USD Billion by 2035. The emphasis on precision medicine further underscores the importance of genomic research in improving healthcare outcomes.

    Rising Prevalence of Genetic Disorders

    The Global Short Read Sequencing Market Industry is significantly influenced by the rising prevalence of genetic disorders. Conditions such as cancer, cardiovascular diseases, and rare genetic disorders are becoming increasingly common, necessitating advanced diagnostic tools for effective management. Short read sequencing technologies enable clinicians to identify genetic mutations and variations that contribute to these diseases. As healthcare systems worldwide prioritize early diagnosis and personalized treatment plans, the demand for short read sequencing is expected to grow. This trend aligns with the projected compound annual growth rate of 9.05% from 2025 to 2035, indicating a robust market trajectory.

    Technological Advancements in Sequencing

    The Global Short Read Sequencing Market Industry is propelled by rapid technological advancements in sequencing technologies. Innovations such as next-generation sequencing (NGS) have significantly reduced the time and cost associated with genomic sequencing. For instance, the cost of sequencing a human genome has decreased from over 100 million USD to approximately 1,000 USD in recent years. This reduction has made genomic analysis more accessible to researchers and healthcare providers worldwide. As a result, the market is projected to reach 7.71 USD Billion in 2024, reflecting the growing adoption of these technologies in various applications, including personalized medicine and genetic research.

    Growing Applications in Personalized Medicine

    The Global Short Read Sequencing Market Industry is witnessing growth due to the expanding applications of short read sequencing in personalized medicine. This approach tailors medical treatment to individual characteristics, needs, and preferences, which is increasingly facilitated by genomic data. Short read sequencing allows for the identification of genetic markers that can inform treatment decisions, particularly in oncology and rare diseases. As healthcare providers adopt personalized medicine strategies, the demand for short read sequencing technologies is expected to rise. This trend is likely to contribute to the market's growth trajectory, aligning with the anticipated increase in market value to 20 USD Billion by 2035.

    Market Segment Insights

    Short Read Sequencing Market Application Insights

    The Short Read Sequencing Market under the Application segment showcases a robust growth trajectory with revenue expected to reach 7.71 USD Billion by 2024 and 20.0 USD Billion by 2035. The market is significantly driven by various key applications including Clinical diagnostics, Agrigenomics, Oncology, Genomics Research, and Molecular Biology, each playing a crucial role in enhancing healthcare and scientific research worldwide.

    Among these applications, Clinical diagnostics emerges as a major driving force, holding a valuation of 2.5 USD Billion in 2024 and growing to 6.4 USD Billion by 2035, underscoring its pivotal role in patient care and disease management.Agrigenomics also commands attention with projections of 1.7 USD Billion in 2024 rising to 4.2 USD Billion by 2035, reflecting the increasing demand for genetic analysis in agriculture to improve crop yields and resistance.

    Oncology, valued at 1.8 USD Billion in 2024 and expected to reach 4.6 USD Billion by 2035, is particularly vital as it offers techniques for the early detection and targeted treatment of various cancers, thus significantly impacting patient outcomes.

    Moreover, Genomics Research is projected to grow from 1.3 USD Billion in 2024 to 3.3 USD Billion by 2035, highlighting its importance in unlocking genetic information that could lead to breakthroughs in personalized medicine.Lastly, Molecular Biology, albeit with a smaller valuation of 0.41 USD Billion in 2024, is anticipated to increase to 1.5 USD Billion by 2035, emphasizing its foundational role in understanding biological processes and advancements in biotechnology.

    The collective contributions of these applications illuminate the market dynamics, as advancements in sequencing technologies drive innovation and adoption across multiple domains, benefiting areas such as diagnostics, therapeutic development, and agricultural enhancements. With substantial Short Read Sequencing Market statistics reflecting the accelerating demand for accurate genetic analysis and personalized solutions, the industry is set for significant growth, reinforced by both technological advancements and the increasing emphasis on genomic-centric approaches in various fields.

    Short Read Sequencing Market Technology Insights

    The Short Read Sequencing Market, focusing on the Technology segment, has shown significant growth trends, underpinned by innovations across various sequencing technologies. As per recent data, the market is expected to achieve a valuation of 7.71 USD Billion by 2024, highlighting its robust expansion. This segment includes prominent technologies like Illumina sequencing, Ion Torrent sequencing, SOLiD sequencing, and SMRT sequencing.

    Illumina sequencing dominates the market due to its widespread adoption in clinical applications and Research and Development, thanks to its high throughput and accuracy.Ion Torrent sequencing is recognized for its rapid and cost-effective solutions, making it valuable in both research and diagnostic settings. Meanwhile, SOLiD sequencing, although less prevalent than others, is noted for its unique sequencing approach that ensures high fidelity, particularly in targeted resequencing studies. Finally, SMRT sequencing stands out for its capability of sequencing long reads, thus providing a fuller genomic picture.

    The Short Read Sequencing Market is influenced by rising demand for genomic data, advancements in sequencing technology, and ongoing initiatives in personalized medicine, all contributing to its projected growth trajectory.

    Short Read Sequencing Market End Use Insights

    The Short Read Sequencing Market, expected to achieve a valuation of 7.71 USD Billion in 2024, is witnessing significant growth driven by its application across various end-use sectors. Academic research institutes are essential as they leverage short read sequencing for groundbreaking discoveries in genomics and molecular biology, providing a foundation for further academic advancements. Pharmaceutical companies utilize this technology for drug development and personalized medicine, making it a pivotal component of R&D efforts.

    Biotechnology companies are heavily invested in this market as they employ sequencing to innovate new therapies and products, showcasing its importance in bioproduct development.Meanwhile, hospitals and clinics incorporate short read sequencing for diagnostics and patient management, highlighting its practical implications in healthcare. The growing demand for precise genetic analysis and the surge in genomic studies and initiatives at the global level have spurred market growth. Overall, the Short Read Sequencing Market segmentation reflects a diversified range of applications, positioning it as a crucial tool in enhancing research, drug development, and clinical practices worldwide.

    Market trends suggest increasing investment in these end-use segments, creating vast opportunities for advancements in genomics and personalized healthcare solutions across the globe.

    Short Read Sequencing Market Product Type Insights

    The Short Read Sequencing Market is expected to experience substantial growth, with a projected valuation of 7.71 USD Billion in 2024. This market, driven by advancements in genomics and biotechnology, is witnessing an increasing demand for various product types essential for sequencing processes. Among these, sequencing kits, sequencing services, and sequencing instruments are critical components contributing to the market's expansion.

    Sequencing kits are fundamental, providing researchers with the necessary tools to conduct genetic analyses, while sequencing services streamline the process for organizations lacking in-house capabilities, demonstrating significant reliance on outsourced solutions.Additionally, sequencing instruments are pivotal in enhancing accuracy and efficiency in sequencing operations, ensuring high-quality results that are essential in fields like clinical diagnostics and personalized medicine. As the Short Read Sequencing Market continues to evolve, navigating through developments, growth drivers, and challenges, the synergy between these product types remains significant for facilitating innovation and improving health outcomes globally.

    Market growth is aligned with the increasing applications of sequencing technology, from basic research to clinical diagnostics, benefiting from supportive government initiatives promoting genomic research and healthcare advancements globally.

    Get more detailed insights about Short-Read Sequencing Market Research Report — Global Forecast till 2035

    Regional Insights

    The Regional analysis of the Short Read Sequencing Market reveals significant variations in growth and valuation across various areas, with North America demonstrating a strong market presence. Valued at 3.45 USD Billion in 2024, this region is expected to reach 8.8 USD Billion by 2035, indicating a substantial contribution to the overall market.

    Europe holds a notable share as well, estimated at 2.25 USD Billion in 2024 and anticipated to grow to 5.7 USD Billion by 2035, driven by advanced Research and Development initiatives and strengthening healthcare infrastructures.In contrast, South America starts at a smaller base of 0.5 USD Billion in 2024, growing to 1.2 USD Billion by 2035, reflecting emerging opportunities in biotechnological applications. Asia Pacific captures attention with a valuation of 1.8 USD Billion in 2024, climbing to 4.5 USD Billion by 2035, signalling an expanding market bolstered by rising investment in genomics and personalized medicine.

    The Middle East and Africa, starting at 0.71 USD Billion in 2024 and progressing to 1.8 USD Billion by 2035, represent growing sectors with increasing awareness and capabilities in genomics.This diverse geographical spread highlights crucial market growth drivers, such as heightened demand for genomic data, advancements in sequencing technologies, and a push towards personalized healthcare solutions.

    Short Read Sequencing Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Short Read Sequencing Market has witnessed significant growth and innovation, driven by advancements in sequencing technologies and increasing applications in genomics, personalized medicine, and genetic research. This market is characterized by a competitive landscape where various players are striving to gain a substantial share through the development of cutting-edge technologies and strategic collaborations. The significant demand from academic research centers, pharmaceutical companies, and biotechnology firms has intensified competition among key stakeholders. As the market evolves, players are focusing on enhancing the efficiency and accuracy of sequencing methods, reducing costs, and improving data analysis capabilities.

    Emerging trends, such as the integration of artificial intelligence and machine learning in sequencing analysis, are also influencing the competitive dynamics within the market.Applied Biosystems has carved out a significant niche in the Short Read Sequencing Market with its focus on delivering high-throughput sequencing solutions that are widely utilized in academic, clinical, and industrial applications. The company's offerings include a range of sequencing instruments, platform solutions, and comprehensive support services designed to enhance the efficiency of sequencing workflows.

    Applied Biosystems is known for its commitment to providing reliable and accurate results, which is pivotal for applications in genomics and personalized medicine. 

    The company's strengths can be attributed to its extensive experience in the field, a robust product portfolio, and ongoing investments in research and development. Additionally, strategic mergers and acquisitions have enabled Applied Biosystems to expand its capabilities and enhance its market reach, allowing them to respond effectively to the evolving demands of the global market and solidify its position as a leader in the short read sequencing arena.

    Key Companies in the Short Read Sequencing Market market include

    Industry Developments

    Recent developments in the Short Read Sequencing Market have shown significant advancements, with companies such as Illumina and Thermo Fisher Scientific pushing the boundaries through innovations in sequencing technologies. As of September 2023, Illumina's acquisition of Grail has been finalized, expanding its presence in the multi-cancer early detection space while enhancing its sequencing capabilities. 

    BGI is also demonstrating growth, leveraging collaborations and partnerships to enhance their product offerings in short read sequencing. The global market is experiencing a surge in funding; for instance, Element Biosciences secured significant investment to enhance its engineering capabilities. Additionally, recent reports indicated that the market demand for short-read sequencing is expected to increase rapidly due to the expansion of applications across healthcare and environmental sectors. 

    Over the past two years, various advancements in technology have decreased costs and improved accessibility, fostering further growth within this competitive landscape, and shaping the future of genomics worldwide.

    Future Outlook

    Short Read Sequencing Market Future Outlook

    The Global Short Read Sequencing Market is projected to grow at a 19.20% CAGR from 2025 to 2035, driven by advancements in genomics and personalized medicine.

    New opportunities lie in:

    • Develop targeted sequencing solutions for rare diseases.
    • Enhance bioinformatics tools for data analysis efficiency.
    • Expand partnerships with pharmaceutical companies for drug discovery applications.

    By 2035, the market is expected to be robust, reflecting substantial advancements and widespread adoption.

    Market Segmentation

    Short Read Sequencing Market End Use Outlook

    • Academic research institutes
    • Pharmaceutical companies
    • Biotechnology companies
    • Hospitals and clinics

    Short Read Sequencing Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Short Read Sequencing Market Technology Outlook

    • Illumina sequencing
    • Ion Torrent sequencing
    • SOLiD sequencing
    • SMRT sequencing

    Short Read Sequencing Market Application Outlook

    • Clinical diagnostics
    • Agrigenomics
    • Oncology
    • Genomics Research
    • Molecular Biology

    Short Read Sequencing Market Product Type Outlook

    • Sequencing kits
    • Sequencing services
    • Sequencing instruments

    Report Scope

    Report Attribute/Metric

    Details

    Market Size 2024

    7.71(USD Billion)

    Market Size 2035

    65.49 (USD Billion)

    Compound Annual Growth Rate (CAGR)

    19.20% (2025 - 2035)

    Report Coverage

    Revenue Forecast, Competitive Landscape, Growth Factors, and Trends

    Base Year

    2024

    Market Forecast Period

    2025 - 2035

    Historical Data

    2019 - 2024

    Market Forecast Units

    USD Billion

    Key Companies Profiled

    Applied Biosystems, Element Biosciences, Thermo Fisher Scientific, PerkinElmer, Agilent Technologies, BGI, Qiagen, Illumina, 10x Genomics, BioRad Laboratories

    Segments Covered

    Application, Technology, End Use, Product Type, Regional

    Key Market Opportunities

    Increased demand for genomics research, Advancements in sequencing technologies, Growth of personalized medicine, Expansion in diagnostics applications, Rise in funding for biotech innovation

    Key Market Dynamics

    Technological advancements, Increasing research funding, Rising prevalence of genetic disorders, Growing demand for personalized medicine, Development of novel applications

    Countries Covered

    North America, Europe, APAC, South America, MEA

    Market Size 2025 11.31 (USD Billion)

    FAQs

    What is the projected market size of the Short Read Sequencing Market by 2035?

    The Short Read Sequencing Market is expected to reach a value of 20.0 USD Billion by 2035.

    What is the expected CAGR for the Short Read Sequencing Market from 2025 to 2035?

    The expected CAGR for the Short Read Sequencing Market from 2025 to 2035 is 9.05%.

    Which region is anticipated to have the largest market share in the Short Read Sequencing Market by 2035?

    North America is anticipated to hold the largest market share in the Short Read Sequencing Market by 2035, valued at 8.8 USD Billion.

    What is the market size of the Clinical Diagnostics application in the Short Read Sequencing Market for 2035?

    The Clinical Diagnostics application is projected to be valued at 6.4 USD Billion in the Short Read Sequencing Market by 2035.

    Who are the key players in the Short Read Sequencing Market?

    Key players in the Short Read Sequencing Market include Applied Biosystems, Thermo Fisher Scientific, and Illumina among others.

    What is the projected market size for Agrigenomics in the Short Read Sequencing Market by 2035?

    The Agrigenomics segment is expected to reach a market size of 4.2 USD Billion by 2035.

    What is the expected market growth rate for the Asia Pacific region in the Short Read Sequencing Market until 2035?

    The Asia Pacific region is projected to grow to a market size of 4.5 USD Billion by 2035.

    What is the market size for Oncology applications in the Short Read Sequencing Market for the year 2024?

    The Oncology application is valued at 1.8 USD Billion in the Short Read Sequencing Market for the year 2024.

    What challenges does the Short Read Sequencing Market face?

    The Short Read Sequencing Market faces challenges such as high costs and regulatory hurdles that can impact growth.

    What trends are influencing the Short Read Sequencing Market currently?

    Emerging trends in the Short Read Sequencing Market include advancements in technology and increasing demand for personalized medicine.

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