The real-time PCR (qPCR) market is expected to cross ~USD 8,398.55 million in 2027 at a CAGR of ~8.92% during the forecast period. Real-Time PCR (qPCR) test is a qualitative detection of nucleic acid from the specimen of a patient suffering from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2). Rising demand for real-time PCR (qPCR) for the treatment of ongoing COVID-19 outbreak and advancements in technology has enabled healthcare professionals to determine the infection level in real-time. This is one of the major factorsboosting the real-time PCR (qPCR) market growth. However, there are pitfalls in the Real-Time PCR (qPCR) market,such as complex regulatory scenarios, high cost, risk of eliciting false negative and positive results, and unaffordability of research fundings in emerging economies.
The rising prevalenceof COVID-19 is projected to impact the real-time PCR (qPCR) market growth over the forecast period positively. As the coronavirus outbreak continues, the need for effective and quick testing is escalating the COVID-19 pandemic.The real-time PCR (qPCR) kit is considered one of the most sought-after methods in the healthcare industry, thereby producing a point in the demand for these kits. This factor is projected to have a positive impact on the real-time PCR (qPCR) market growth, which in turn also aids in driving the real-time PCR (qPCR) market growth.
Many research organizations and universities are giving outstanding support by providing real-time PCR (qPCR) platforms for conducting various tests, one of the most accurate laboratory methods for detecting, tracking, and studying the COVID-19 virus. Furthermore, government initiatives supporting the approvedreal-time PCR (qPCR) kits to help diagnose COVID-19 are also a boosting factor. For instance, the Indian government approved 12 rapid antibody test kits for COVID-19 diagnosis. The Indian Council Medical Research(ICMR)has also issued guidance on rapid antibody test kits for COVID-19.
Rising demand for Real-Time PCR amid COVID-19 pandemic
According to apublished article in PubMed in April 2020, false-negative results may occur by mutations in the primer and probe-target regions in the SARS-CoV-2 genome. In addition, false-negative results may occur due to the presence of amplification inhibitors in the sample. Hence, the sensitivity and specificity of the RT-PCR test arenot 100% valid, which is limiting the growth of Real-Time PCR (qPCR) market. Many laboratory practice standards and personnel skills in the relevant technical and safety procedures often face false-negative results.
During the COVID-19 outbreak, testing of viral load kinetics in different anatomic sites of the patients, sampling procedures carried out by real-time PCR (qPCR) largely contribute to the false-negative results. False-negative results may occur due to amplification inhibitors present in the sample or insufficient organisms in the sample rising from inappropriate collection,transportation, or handling.
Among many technological advancements in the medical industry, nucleic acid detection-based approaches have become a rapid and reliable technology for viral detection. The qualitative PCR method is considered the ‘gold standard’ for the detection of viruses and is characterized by high sensitivity, rapid detection, and specificity. Research fundings are being carried out in many countries to support COVID-19 treatment. For instance, in 2020,Pune-based Mylab Discovery developed a real-time PCR-based molecular diagnostic kit that screens and detects samples of patientshaving flu-like symptoms. The kit was developed and approved by ICMR and CDSCO, production of kits was ramped up in a short time from 30,000 tests to 2 lakhs tests per day.
Quantitative real-time PCR (qPCR) is of great interests due to its benefits as a specific and simple qualitative assay. Moreover, real-time (qPCR)has adequate sensitivity for diagnosing early infection.
Value Chain Analysis
The global real-time PCR (qPCR) market is growing steadily due to the emerging number of players in the marketinvolved in new product launches, acquisitions, and strategic collaborations. The value chain analysis of the real-time PCR (qPCR) market comprises four major components starting with the R&D and designing, followed by manufacturing the products, distribution & sales, and ends with post-sales services.
The R&D designing of real-time PCR (qPCR) starts with conceptualizing, followed by design, then development, and lastly, testing. The R&D segment comprises 25-30% of the value chain of real-time PCR (qPCR). After the product designs are final, the manufacturing of the product starts. Manufacturing consists of 35-40% of the value chain of real-time PCR (qPCR).
The various reagents and assays used for real-time PCR assay are Template cDNA, Upstream and downstream primers, GoTaq DNA Polymerase with reaction buffer, dNTP mixture, Molecular grade, nuclease-free water, and Agarose. Increasing use of reagents and assays such as TaqMan Real-time PCR assays is expected to lead the market throughout the study period in this segment.
Real-Time consumables include plastics and supplies for qPCR experiments, including tubes, plates, caps, adhesive plate seals, strips, and racks. They are validated for optimal performance with the real-time PCR Systems. Increasing the use of these real-time PCR consumables to carry out various molecular procedures in real-time PCR systems is fueling the real-time PCR (qPCR) market growth of this segment.
Rising efforts by PCR manufacturers to develop novel real-time PCR instrument systems and kits to use in molecular testing are projected to stimulate the growth for real-timePCR (qPCR) market. For instance, in January 2019, Qiagen N.V. developed the next-generation dPCR systems, and the company launched the system in 2020. In addition, the new system offers highly automated workflows and quicker turnaround time compared to current digital PCR platforms, which provided the company significant competitive advantage.
The software &services for real-time PCR (qPCR) helps to guides users towards sound and powerful data analysis. These softwaresare designed to streamline the process of real-time PCR data collection and analysis. The increasing use of these softwares for the accurate results of experiments conducted and for carrying out molecular procedures is fueling the real-time PCR (qPCR) market growth of this segment.
The increasing number of acute and chronic diseases that require molecular testing is augmenting the market growth for the real-time PCR market. In addition, technological advancements in molecular assays and techniquesandthe proven efficacy ofreal-time PCR (qPCR) analysis in the diagnosis have further enhanced the use of clinical diagnostic tests (including qPCR analysis). These factorsare supportingthe growth of this segment.
Increasing usage of real-time PCR techniques in drug development and research activities is propelling the real-time PCR (qPCR) market growth of this segment. Increasing R&D spendings by many biotechnology & pharmaceutical companies is another key contributing factor for the market growth. For instance, In 2019, the global pharmaceutical industry spent USD 83 billion on R&D, which was observedtentimes what the industry spent per year in the 1980s. Thus, this rising investment in R&D is contributing towards driving this segment.
DNA profiling (DNA testing, DNA typing,genetic fingerprinting) is a technique used by forensic scientists to identify an individual based on their DNA profile. Real-time PCR can be used as a tool in DNA fingerprinting. This technology can identify any person from millions which isanticipated to accelerate the real-time PCR (qPCR) market growth of this segment. Therefore, the rising adoption of real-time PCR for the DNA fingerprinting process is driving the real-time PCR (qPCR) market growth of this segment.
The other applications of the real-time (qPCR) market include the food & beverage industry (F&B) and agriculture industry.Real-time (qPCR) is an important analytical method in food as well as in medical diagnostics. Increasing adoption of real-time (qPCR) in F&B industries and agriculture industriesto quantify crops is thus driving the real-time PCR (qPCR) market growth of this segment.
By End Users
Hospitals & diagnostic centers segment dominated the real-time PCR (qPCR) market owing to the ongoing expansion of healthcare infrastructure across emerging countries; increasing market availability of qPCR reagents& instruments in various clinical diagnostic applications; high prevalence & incidence of target diseases such as HIV-AIDS, malaria, cancer, and tuberculosis; and rising awareness among end users related to the various advantages offered by real-time (qPCR) in rapid & effective disease diagnosis.
qPCR and dPCR systems are widely used in various research laboratories and academic institutes.The widespread use of these systems is attributed to features such as enhanced specificity and quick turnaround time. This factor, in turn, aids to boost the real-time PCR (qPCR) market growth of this segment.
Furthermore, the increasing use of real-time PCR (qPCR) instrument systemsin drug development will boost the real-time PCR (qPCR) market growth for real-time PCR (qPCR) products in biotechnology and pharmaceutical industries which is also contributing to the real-time PCR (qPCR) market growth during the study period.
Real-time PCR (qPCR) is vital for the progression of drug discovery, enabling detection and quantification of various diseases, and it is commonly used in many pharmaceutical and biotechnology companies. This factor is acting as a key factor for the growth of this segment.
The increasing adoption of real-time PCR for the number of clinical applications in many clinical research organizations has increased substantially. For instance, in the field of clinical microbiology, oncology, and gene therapy,real-time PCR (qPCR) is a standard method for disease detection, which is further acting as a key contributing factor for the growth of this segment.
The increasing number of qPCR assays being developed in single and multiplex modes for quantifying DNA in forensic samplesby the forensic laboratories is acting as a driving factor for the segment. These assays are developed to improve the accuracy and precision of DNA quantifications and provide tools to increase the efficiency and throughput of the analysis of forensic samples.
The market in North America accounted for the largest share in 2020 due to the presence of constant technological developments followed by discoveries triggering the adoption ofnovel methods of molecular methods by the major players of this region. The majormarket players such asABL SA Group (Luxembourg), Agilent Technologies, Inc. (US), Analytik Jena AG (Germany), BD (US), Bio-Rad Laboratories, Inc. (US), F. Hoffmann-La Roche Ltd (Switzerland) are contributing to the real-time PCR (qPCR) market growth. For instance, in August 2020, Thermo Fisher Scientific Inc. (US) launched a highly automated, real-time PCR solution that is designed to analyze up to 6,000 samples in a day to meet the rising number of cases and testing required for the COVID-19 pandemic.
The European real-time PCR (qPCR) market is driven by supportive government Real-Time PCR (qPCR) procedures and increasing demand for Real-Time PCR testing to fight against infectious diseases such as COVID-19. In addition, increasing demand for rapid diagnostics, rising prevalence of infectious and genetic disorders, and rapid technological advancements are driving the real-time PCR (qPCR) market growth of the real-time PCR (qPCR) market.
The Asia-Pacific is expected to witness rapid growth in the global real-time PCR (qPCR) market throughout the assessment period. The Asia-Pacific regional market is anticipated to witness lucrative growth due to the presence of government and private sector companies regulating biotechnology products. For instance, in India, the Department of Biotechnology (DBT), the Department of Science and Technology (DST), Department of Scientific & Industrial Research (DSIR) are regulating the production and guidelines for biotechnology products. These organizationsprovide guidelines related to manufacturing or transferring technology and generate manpower for production raising funds.
The real-time PCR (qPCR) market in the rest of the world is driven by technological development in manufacturing, screening technologies, the biotechnology industry, and assays. The increasing number of government initiatives for improving the healthcare sector is another factor boosting the growth of the real-time PCR (qPCR) market in this region.
The real-time PCR (qPCR) market is profitable, both for existing players and new entrants. A substantial level of competitive rivalry is witnessed among the market players. Based on the analysis, market players have adopted different strategies and innovative research and development techniques to expand their business and secure their position in the global real-time PCR (qPCR) market. For instance, in 2018, Denali Therapeutics (US)entered into a partnership with Lonza (Switzerland) to develop and produce biologic medicines using the latter’s real-Time PCR (qPCR) technology GS Xceed.The prominent players are involved in product launches, strategic agreements, and joint ventures to mark their presence in the real-time PCR (qPCR) market.
Bio-rad Laboratories has robust industry experience and is one of the leading companies in the real-timePCR market. Furthermore, a high customer satisfaction level, exceptional performance in new markets, and a strong product portfolio add to the company’s competitive advantage. The company also has a strong clientele and is well established in the industry. The company is continuously involved in seminars, conferences, and trade fairs in several countries to generate awareness about its products.
The study covers the existing short-term and long-term market effects, as well as helping decision-makers to draught short-term and long-term plans for businesses by region. The report covers major regions in North America, Europe, Asia-Pacific, and theRest of the World. The report analyzes market drivers, restraints, opportunities, challenges, Porter’s Five Forces, Value Chain, and impact of COVID-19 on the market.
Scope of the Report
The scope of the global real-time PCR (qPCR)market study includes a market size analysis and a detailed analysis of the manufacturer’s products and strategies. The real-time PCR (qPCR) market has been segmented based on product, application, end user, and region.
Real-Time PCR (qPCR), by Product
Real-Time PCR (qPCR), by Application
Real-Time PCR (qPCR), by End User
Real-Time PCR (qPCR), by Region
|Market Size||2027:~USD 8,398.55 Million|
|Forecast Units||Value (USD Million)|
|Report Coverage||Revenue Forecast, Competitive Landscape, Growth Factors, and Trends|
|Segments Covered||Product and Application|
|Geographies Covered||North America, Europe, Asia-Pacific, Rest of the World|
|Key Vendors||• ABL SA Group (Luxembourg) • Agilent Technologies, Inc. (US) • Analytik Jena AG (Germany) • BD (US) • Bio-Rad Laboratories, Inc. (US) • F. Hoffmann-La Roche Ltd (Switzerland) • Fluidigm Corporation (US) • Lumex Instruments (US) • Primerdesign Ltd (UK) • QIAGEN (Germany) • Takara Bio Inc. (Japan) • Thermo Fisher Scientific (US) • TOYOBO Inc. (Japan) • Vela Diagnostics (Singapore)|
|Key Market Opportunities||Increasing adoption of real-time PCR kits to overcome the pandemic situation|
|Key Market Drivers||• Rising demand for Real-time PCR amid COVID-19 pandemic • Increasing prevalence of target diseases and technological advancements in qPCR|
The real-time PCR (qPCR) market is expected to cross ~USD 8,398.55 million in 2027 at a CAGR of ~8.92% during the forecast period.
ABL SA Group (Luxembourg), Agilent Technologies, Inc. (US), Analytik Jena AG (Germany), BD (US), Bio-Rad Laboratories, Inc. (US), F. Hoffmann-La Roche Ltd (Switzerland), Fluidigm Corporation (US), Lumex Instruments (US), Primerdesign Ltd (UK), QIAGEN (Germany), Takara Bio Inc. (Japan), Thermo Fisher Scientific (US), TOYOBO Inc. (Japan), and Vela Diagnostics (Singapore) are the key players in the market of real time pcr (qpcr)
North America is predicted to lead the the market of real time pcr (qpcr)
Rising demand for Real-Time PCR amid COVID-19 pandemic is the major market driver of real time pcr (qpcr)
Risk of eliciting false-negative and false-positive results may limit the market growth of real time pcr (qpcr)