Liquid chromatography Instruments Market Summary
As per MRFR Analysis, the Global Liquid Chromatography Instruments Market was valued at USD 2.9 billion in 2023 and is projected to grow from USD 3.0 billion in 2024 to USD 4.7 billion by 2032, with a CAGR of 3.5% during the forecast period. Key drivers include increasing demand for hyphenated chromatography techniques, reduced contamination risks, and improved automation. Waters Corporation's HPLC CONNECT software, launched in February 2024, enhances digital synchronization for HPLC systems, supporting complex biopharmaceutical analyses. The market is segmented by technique, with high-performance liquid chromatography (HPLC) leading in revenue. The pharmaceutical sector is the largest end-user, driven by drug testing and development applications. North America holds the largest market share, followed by Europe and Asia-Pacific, which is expected to grow the fastest due to rising clinical research potential.
Key Market Trends & Highlights
The liquid chromatography instruments market is witnessing significant trends driven by technological advancements and increasing applications.
- Market Size in 2023: USD 2.9 billion.
- Projected Market Size by 2032: USD 4.7 billion.
- CAGR from 2024 to 2032: 3.5%.
- North America accounted for USD 1.3282 billion in 2022.
Market Size & Forecast
2023 Market Size: USD 2.9 billion
2024 Market Size: USD 3.0 billion
2032 Market Size: USD 4.7 billion
CAGR (2024-2032): 3.5%
Largest Regional Market Share in 2022: North America.
Major Players
Key players include Waters Corporation, Thermo Fisher Scientific, Shimadzu, PerkinElmer, and Agilent Technologies.
Source: Secondary Research, Primary Research, MRFR Database and Analyst Review
Waters Corporation has announced the release of HPLC CONNECT software in February 2024. This all-in-one software platform facilitates complete digital synchronization between Waters high- and ultra-performance liquid chromatography (HPLC/UPLC) systems and multi-angle light-scattering instruments (MALS) from its Wyatt Technology portfolio. The software provides scientists with increased confidence, greater efficiency, and ease of use when conducting size exclusion chromatography and MALS (SEC-MALS) analyses for complex and critical biopharmaceutical innovations, such as antibody drug conjugates, other complex protein conjugates, and gene therapies. The ACQUITY Premier, Arc Premier, and Arc Systems are among the Waters LC systems that are supported by the HPLC CONNECT software. The software allows users to manage and supervise HPLC modules, such as compressors, column ovens, UV detectors, and autosamplers, from a single dashboard view. Waters provides a comprehensive selection of SEC columns that are specifically designed to separate biomolecules by size. These columns are most suitable for the separation of monoclonal antibodies, proteins, peptides, and other biologics. The Waters HPLC CONNECT software is now accessible worldwide.
Liquid Chromatography Instruments Market Trends
Growing Demand for Hyphenated Chromatography Techniques to Fuel Market Growth
Chromatic separation method using UV. Dash methods include detection and identification methods using I.R. (Infrared) and NMR (Nuclear Magnetic Resonance) spectrometers. Increasing demand for coupled chromatography techniques such as LC-NMR, LC-MS, LC-FTIR and GC-MS is expected to fuel the market CAGR.
In addition, drug quality assessment and use in drug development are expected to boost market growth. In addition, the increasing importance of chromatography testing in the drug approval process and the rapid availability of several liquid chromatography instruments in laboratories dampen the market's growth during the forecast period. The growth of generics and CROs and the therapeutic shift to new biological entities will positively impact future liquid chromatography device market growth rates.
Figure 1:Average Annual Approvals of New Drugs by the FDA from 1980-2019 (in number of drugs)
Source: Secondary Research, Primary Research, MRFR Database and Analyst Review
Increased investment in this area by research users and government agencies provides growth opportunities for market growth. Moreover, it is estimated that the advanced development will reduce downtime, and the cost required for maintenance will bring more opportunities to the market.
However, the high cost of devices and alternative techniques will pose a challenge that may hinder the development of the liquid chromatography instruments market revenue.
Liquid Chromatography Instruments Market Segment Insights
Liquid Chromatography Instruments Technique Insights
The liquid chromatography instruments market segmentation, based on technique, includes high-performance liquid chromatography (HPLC), ultra-high-pressure liquid chromatography (UHPLC), low-pressure liquid chromatography (FPLC), and fast protein liquid chromatography (FPLC). The high-performance liquid chromatography instruments segment held the majority share in 2022 with respect to the liquid chromatography instruments market revenue. A higher resolution, reproducible responses, better peak shape, and speed of analysis are fueling this growth.
November 2020:PerkinElmer Inc. introduced a novel HPLC, UHPLC, and software solution, LC 300TM platform and Simplicity ChromTM software.
Liquid Chromatography Instruments Type Insights
Based on type, the Liquid Chromatography Instruments market segmentation includes instruments, consumables, and services. The instruments segment dominated the market in 2022 and is anticipated to be the faster-growing segment during the forecast period, 2023-2030. It is owing to the growing domination of integrated HPLC systems and the accessibility of advanced detectors. These systems deliver high-speed sampling volumes and low carryover for excellent control uses. Furthermore, Aqueous and organic compatible detectors such as activated research's solver carbon selective detector extend the applicability of HPLC technology to a variety of sample types.
March 2021:ES Industries was acquired by PerkinElmer, Inc. to enhance liquid chromatography columns to its consumable portfolio.
Figure 2: Liquid Chromatography Instruments Market Share By Type 2023-2032 (USD Billion)
Source: Secondary Research, Primary Research, MRFR Database and Analyst Review
Consumables such as columns and filters are expected to become increasingly important due to improved column chemistries and packaging materials and the growing importance of filtration techniques to protect HPLC columns from particulate contamination. The increasing demand for sensitive chromatographic operations has led to a focus on reducing analyte-metal interactions that can affect results. It can be accomplished with the help of advanced metal passivation or using PEEK (polyetheretherketone)-lined stainless steel columns. Hence, rising type options for liquid chromatography instruments positively impact the market growth.
Liquid Chromatography Instruments Service End User Insights
Based on function, the liquid chromatography instruments market data includes academics & research institutes, pharmaceutical companies, hospitals, and the agriculture industry. The pharmaceutical companies' Liquid Chromatography Instruments segment held the majority share in 2021 with respect to the Liquid Chromatography Instruments market revenue. It is owing to the varied applications of chromatography in drug testing and stabilization, research applications, etc. An increase in investments by pharmaceutical and biotech companies is another driver. For instance, in June 2020, Waters Corporation launched its new high-performance liquid chromatography (HPLC) Waters Arc HPLC System.​ The company announced that the new liquid chromatography system could be used for routing testing in various end-use areas, such as the food & beverage, pharmaceutical, and academic and materials markets.
Liquid Chromatography Instruments Regional Insights
By region, the study offers market insights into Asia-Pacific, Europe, North America, and Rest of the World. The North America Liquid Chromatography Instruments market accounted for USD 1.3282 billion in 2022 and is anticipated to exhibit a substantial CAGR growth during the study period. The United States Liquid Chromatography Instruments market held the largest market share, and the Canada Liquid Chromatography Instruments market was the fastest-growing market in the North American region. Swift growth in the pharmaceutical industry, extraordinary research and development spending, and increasing demand for regional clinical diagnostic applications.
Further, the key countries studied in the market report are: The U.S, Canada, UK, Italy, Germany, France, Spain, China, Japan, India, Australia, South Korea, and Brazil.
Figure 3: LIQUID CHROMATOGRAPHY INSTRUMENTS MARKET SHARE BY REGION 2023 (%)
Source: Secondary Research, Primary Research, MRFR Database and Analyst ReviewEurope's liquid chromatography instruments market accounts for the second-largest market share due to the increasing spending on the healthcare sector from the U.K., Germany, France, Russia, and others. Furthermore, increasing investments in biomedical industries, growing healthcare infrastructure, rising disposable incomes, and well-established domestic companies within the region. Moreover, the UK liquid chromatography instruments market held the largest market share whereas Germany liquid chromatography instruments market is the fast growing in the Asia-Pacific region.
The Asia-Pacific liquid chromatography instruments market is anticipated to develop at the fastest CAGR from 2023 to 2030. It is due to the high potential for clinical research in this area due to the many patients available. Additionally, large-scale production of generic drugs and biosimilars in countries such as China and India offers promising growth opportunities for introducing quality control and testing procedures. In addition, HPLC research applications for analyzing conventional dosing options, such as Traditional Chinese herbal medicines, will open up new growth avenues in the market. Moreover, the China liquid chromatography instruments market held the largest market share whereas India liquid chromatography instruments market is the fast growing in the Asia-Pacific region.
Liquid Chromatography Instruments Key Market Players & Competitive Insights
Major market players are spending a large portion of money on Research & Development to increase their product lines, which will help the Liquid Chromatography Instruments market grow further. Market players are also taking several strategic initiatives to enhance their worldwide impression, with major market developments such as contractual agreements, new product launches, increased investments, mergers and acquisitions, and collaboration with other organizations. Competitors in the Liquid Chromatography Instruments industry must offer cost-effective products and services to increase and persist in a progressively competitive and expanding market environment.
One of the key business strategies manufacturers adopt in the liquid chromatography instruments industry to benefit clients and expand the market sector is increasing investment in R&D to enhance solutions and services. In recent years, the Liquid Chromatography Instruments industry has provided transparency and reduced disruptions in the supply chain. The Liquid Chromatography Instruments markets major players such as Shimadzu (Japan), Phenomenex (US), Hitachi (Japan), Hamilton Company (US), Thermo Fisher (US), Tosoh Bioscience LLC (Japan), Orochem (US), Showa Denko (Japan) and others are working on expanding the market demand by investing in research and development activities.
Thermo Fisher's instruments, software, scientific instruments, services, and consumables meet a variety of needs, from sample & material characterization and chemical analysis to clinical diagnostics & biotherapeutic manufacturing. For instance, in February 2021, Thermo Fisher Scientific launched its Vanquish Online 2D-Liquid Chromatography (LC) system, which offers versatility for multidimensional liquid chromatography.
Also, Shimadzu Scientific Instruments (SSI) is the American subsidiary of Shimadzu Corporation (Kyoto, Japan). Its distribution center provides analytical solutions to various laboratories and lab services providers in the Americas. For instance, in October 2022, Shimadzu Scientific Instruments launched the new i-Series LC-2050/LC-2060 Integrated High-Performance Liquid Chromatographs (HPLC). Building on the exceptional performance of previous versions, the i-Series LC-2050/LC-2060 models incorporate Analytical Intelligence functions, enable complete automation from start-up to analysis preparations, and allow remote monitoring and data processing.
Key Companies in the Liquid Chromatography Instruments market include
• GE Healthcare (US)
• Merck Millipore (Germany)
• Shimadzu (Japan)
• Phenomenex (US)
• Hitachi (Japan)
• Hamilton Company (US)
• Thermo Fisher (US)
• Gilson (US)
• YMC Co. Ltd. (Japan)
• Trajan Scientific (Australia)
• SIELC (US)
• JASCO (US)
• Tosoh Bioscience LLC (Japan)
• Orochem (US)
• Showa Denko (Japan)
Liquid Chromatography Instruments Industry Developments
July 2022:PerkinElmer, Inc. launched the GC 2400 Platform, an advanced, automated gas chromatography (GC), headspace sampler, and GC/mass spectrometry (GC/MS) solution designed to help lab teams simplify lab operations, drive precise results, and perform more flexible monitoring.
May 2022:Agilent Technologies signed a collaboration agreement with APC Ltd., in which the companies committed to combining their technologies to provide unique workflows to customers that support automated process analysis via liquid chromatography (LC).
Liquid Chromatography Instruments Market Segmentation
Liquid Chromatography Instruments Technique Outlook
Liquid Chromatography Instruments Type Outlook
Liquid Chromatography Instruments End User Outlook
Liquid Chromatography Instruments Regional Outlook
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| Attribute/Metric |
Details |
| Market Size 2023 |
USD 2.9 billion |
| Market Size 2024 |
USD 3.0 billion |
| Market Size 2032 |
USD 4.7 billion |
| Compound Annual Growth Rate (CAGR) |
3.5% (2024-2032) |
| Base Year |
2023 |
| Market Forecast Period |
2024-2032 |
| Historical Data |
2018 & 2021 |
| Market Forecast Units |
Value (USD Billion) |
| Report Coverage |
Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends |
| Segments Covered |
Technique, Type, End-User, and Region |
| Geographies Covered |
North America, Europe, Asia Pacific, and Rest of the World |
| Countries Covered |
The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil |
| Key Companies Profiled |
Merck Millipore (Germany), Shimadzu (Japan), Phenomenex (US), GE Healthcare (US), Thermo Fisher (US), Gilson (US), Hitachi (Japan), Hamilton Company (US), SIELC (US), JASCO (US), Tosoh Bioscience LLC (Japan), YMC Co. Ltd. (Japan), Trajan Scientific (Australia), Orochem (US), and Showa Denko (Japan) |
| Key Market Opportunities |
Increasing Investments and Advancements to Aid Market Growth |
| Key Market Dynamics |
Growing Demand for Hyphenated Chromatography Techniques to Fuel Market Growth. Importance of chromatography in novel drug approvals |
Liquid chromatography Instruments Market Highlights:
Frequently Asked Questions (FAQ) :
The market size of the Liquid Chromatography Instruments was valued at USD 2.9 billion in 2023.
The market is projected to grow at a CAGR of 3.5% during the forecast period 2024-2032.
North America had the largest share of the market
The key players in the market are Shimadzu (Japan), Phenomenex (US), Hamilton Company (US), Thermo Fisher (US), Hitachi (Japan), GE Healthcare (US), Merck Millipore (Germany), Gilson (US), YMC Co. Ltd. (Japan), Tosoh Bioscience LLC (Japan), Orochem (US), Trajan Scientific (Australia), SIELC (US), JASCO (US) and Showa Denko (Japan), and others.
The High-Performance Liquid Chromatography (HPLC) Liquid Chromatography Instruments category dominated the market in 2022.
The Instrument type had the largest share of the market.
