As per MRFR Analysis, the Global Low-Pressure Liquid Chromatography Market was valued at USD 5.9 Billion in 2023 and is projected to grow to USD 10.4 Billion by 2032, with a CAGR of 6.40% from 2024 to 2032. Key drivers include increased investment in drug development, modernization of lab facilities, and the rising use of protein-based vaccinations. The market is supported by government funding for research and development, particularly in North America, Europe, and Asia-Pacific, where significant advancements in clinical research infrastructure are being made.
The Low-Pressure Liquid Chromatography market is witnessing significant growth driven by technological advancements and increased investments.
Key players include Novasep, LEWA GmbH, Biolinx Labsystems, Bio-Rad Laboratories Inc., Danaher Corporation, and Nilsan Nishotech Systems Pvt. Ltd.
Component: Secondary Research, Primary Research, MRFR Database and Analyst Review
The market for low-pressure liquid chromatography is being driven by rising investments in pharmaceutical development, an increase in R&D facilities, modernization of lab facilities, and favourable government regulatory requirements. Additionally, market participants engage in business activities like joint ventures, product launches, service agreements, and affiliations with both public and private research organisations. The market for low-pressure liquid chromatography is anticipated to expand over time as a result of the government authorities investing more money in the infrastructure for conducting research. The infrastructure for clinical research and medication development is being modernised and technologically advanced by government agencies in nations including the US, India, China, and Japan. These elements are the market catalysts for low-pressure liquid chromatography and are anticipated to expand over the forecast period.
The protein-based vaccinations are still in the early stages of clinical testing but have great promise as medicines. The market for low-pressure liquid chromatography is being driven by the rising interest in the development of vaccines based on peptides. The peptide-based medications are affordable, secure, and efficient. Additionally, employing protein subunits, pharmaceutical companies are creating treatments for acellular pertussis and hepatitis-B. Additionally, during the COVID-19 outbreak, scientists from all around the world were eager to create protein-based subunit vaccines. A protein-based vaccine to treat Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was created by UK researchers in November 2020. These vaccines will eventually replace mRNA-based vaccinations in use. Companies like Sanofi (France) and GSK (UK) are working together to produce the COVID-19 recombinant protein vaccine. The third phase of the clinical study for the COVID-19 recombinant vaccine was to begin, according to the company's announcement in May 2021. The business is examining the outcomes of the earlier clinical studies for the recombinant protein vaccine, and it anticipates receiving vaccination approval by the fourth quarter of 2021. The creation of such a cutting-edge vaccination is anticipated to fuel the expansion of the low-pressure liquid chromatography market over the forecasted period.
Government organisations in the United States, Europe, and Asia Pacific are continually investing in and providing grants and cash for the development of liquid chromatography as a result of growing public knowledge of this technique. This will broaden the potential for the creation of new chromatographic technologies, which will promote the expansion of the  liquid chromatography market. Government funding for medical research is increasing, which is fueling demand for liquid chromatography equipment. This element will probably influence the market. The Asia Pacific region's investments in biomedical businesses are a significant driver of the  liquid chromatography market's expansion. The worldwide liquid chromatography market is therefore anticipated to grow as a result of increasing government backing and associated organisations. Additionally, the use in drug development and quality assessment of pharmaceutical products is anticipated to drive market expansion. Additionally, the market's growth is moderated during the anticipated period by the accessibility of some liquid chromatography instruments in labs and the growing significance of chromatography tests in the medication approval process. The development of generics and CROS together with the therapeutic conversion to new biological entities will have a beneficial impact on the growth rate of the liquid chromatography devices market in the future. Thus, driving the Low-Pressure Liquid Chromatography market revenue.
The Low-Pressure Liquid Chromatography market segmentation, based on component, includes instruments, consumables, and services. Instruments segment accounted for the largest revenue share in 2022. It is a specific kind of tool used for precise work. Chromatographic separations are carried out using these tools. Products including pumps, detectors, columns, and flow cells are among the instruments.
The Low-Pressure Liquid Chromatography market segmentation, based on end user, includes pharmaceutical companies, biotechnology companies, research laboratories, and academic institution. Pharmaceutical companies segment dominated the Low-Pressure Liquid Chromatography market in 2022. It is a particular kind of business that develops, investigates, and manufactures both generic and name-brand drugs. Low-pressure liquid chromatography equipment is used by pharmaceutical companies to develop new generic and specialised medications.
Figure 1: Â Low-Pressure Liquid Chromatography Market, by End User, 2022 & 2032 (USD Billion)
Component: Secondary Research, Primary Research, MRFR Database and Analyst Review
By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North America Low-Pressure Liquid Chromatography Market dominated this market in 2022 (45.80%). This is due to increased investment in adeno-associated viral therapy, increased use of precise and effective liquid chromatography, and increased funding for the creation of new products based on gene therapy. The market for low-pressure liquid chromatography products is also quickening due to the region's growing elderly population and rising demand for diagnostic testing. The market for low-pressure liquid chromatography in North America is anticipated to be driven by these factors. Further, the U.S. Low-Pressure Liquid Chromatography market held the largest market share, and the Canada Low-Pressure Liquid Chromatography market was the fastest growing market in the North America region.
Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.
Figure 2: Â LOW-PRESSURE LIQUID CHROMATOGRAPHY MARKET SHARE BY REGION 2022 (USD Billion)
Component: Secondary Research, Primary Research, MRFR Database and Analyst Review
Europe Low-Pressure Liquid Chromatography market accounted for the healthy market share in 2022. The Europe low-pressure liquid chromatography market is being driven by the growing use of gene therapy in the area. Further, the German Low-Pressure Liquid Chromatography market held the largest market share, and the U.K Low-Pressure Liquid Chromatography market was the fastest growing market in the European region
The Asia Pacific Low-Pressure Liquid Chromatography market is expected to register significant growth from 2023 to 2032. The advent of new diseases, the rising elderly population, rising spending in research facilities, and supportive governmental policies are to blame for this. In the estimated time frame, these variables are anticipated to fuel the market need for low-pressure liquid chromatography. Additionally, rising investment to support current clinical studies and drug research is expected to speed up the region's sales of low-pressure liquid chromatography. Moreover, China’s Low-Pressure Liquid Chromatography market held the largest market share, and the Indian Low-Pressure Liquid Chromatography market was the fastest growing market in the Asia-Pacific region.
Low-Pressure Liquid Chromatography Key Market Players & Competitive Insights
Leading market players are investing heavily in research and development in order to expand their product lines, which will help the Low-Pressure Liquid Chromatography market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their  footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Low-Pressure Liquid Chromatography industry must offer cost-effective items.
Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the  Low-Pressure Liquid Chromatography industry to benefit clients and increase the market sector. In recent years, the Low-Pressure Liquid Chromatography industry has offered some of the most significant advantages to medicine. Major players in the Low-Pressure Liquid Chromatography market, including Novasep, LEWA GmbH, Biolinx Labsystems, Bio-Rad Laboratories Inc., Danaher Corporation, and Nilsan Nishotech Systems Pvt. Ltd., are attempting to increase market demand by investing in research and development operations.
Danaher Corp. (Danaher) develops, produces, and sells industrial, commercial, professional, and medical goods and services. A wide range of testing equipment, communications solutions, water quality systems, medical diagnostic solutions, life science research tools, professional microscopes, product identification solutions, sustainable packaging design solutions, automation solutions, and sensors and controls solutions are all available. In Europe, Australia, Asia, and the Americas, the corporation has facilities for manufacturing, sales, distribution, service, and administration. Through direct sales representatives and independent distributors, the company reaches customers throughout the Americas, Europe, the Middle East, Africa, and Asia-Pacific with its products. Washington, DC, in the US, serves as the company's headquarters. In order to increase its knowledge of low-pressure liquid chromatography technology, Danaher Corporation (US) purchased General Electric's Healthcare Life Sciences Biopharma Business in December 2019. Purification is a feature of GE's KTAprocess, a low-pressure liquid chromatography system. The purchase broadened the business's offering in the low-pressure liquid chromatography sector.
One of the top producers and providers of low-pressure liquid chromatography equipment and supplies is Bio-Rad Laboratories, Inc. (US). The BioLogic LP low-pressure chromatography system from Bio-Rad Laboratories, Inc. (US) is used in particular for the purification of biomolecules. Because of its small size, the device requires less installation area. For the purpose of detecting proteins and nucleic acids, the device has 254 and 280 nm filters built in. A conductivity cell is also included in the system to track gradient development. The dual-channel peristaltic pump, which is integrated with the low-pressure liquid chromatography system, generates a back pressure of 30 psi. The company sells a variety of accessories, such as the BioFrac Fraction Collector, Model 2110 Fraction Collector, Econo Gradient Pump, Biologic LP Valves, and Biologic LP Data View Software.
Key Companies in the Low-Pressure Liquid Chromatography market include
Low-Pressure Liquid Chromatography Industry Developments
July 2022: In conjunction with scientists at the Plant Protein Innovation Centre (PPIC) at the University of Minnesota, Waters Corporation has announced that it would contribute both technology and experience to help improve the study of plant-based proteins. To create a methodology for analysing the amino acid composition of plant-based proteins using a Waters ACQUITYTM Premier UPLC System, Waters experts will collaborate with PPIC researchers. Waters is the first manufacturer of analytical instruments to join the PPIC, a preeminent interdisciplinary research centre devoted to the study of plant and alternative proteins.
| Report Attribute/Metric | Details |
| Market Size 2023 | USD 5.9 Billion |
| Market Size 2024 | USD 6.33 Billion |
| Market Size 2032 | USD 10.4 Billion |
| Compound Annual Growth Rate (CAGR) | 6.40% (2024-2032) |
| Base Year | 2023 |
| Market Forecast Period | 2024-2032 |
| Historical Data | 2019- 2022 |
| Market Forecast Units | Value (USD Billion) |
| Report Coverage | Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends |
| Segments Covered | Component, End User, and Region |
| Geographies Covered | North America, Europe, Asia Pacific, and the Rest of the World |
| Countries Covered | The U.S., Canada, German, France, U.K, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil |
| Key Companies Profiled | Novasep, LEWA GmbH, Biolinx Labsystems, Bio-Rad Laboratories Inc., Danaher Corporation, and Nilsan Nishotech Systems Pvt. Ltd. |
| Key Market Opportunities | Increasing investment in R&D activities |
| Key Market Dynamics | Increasing prevalence of protein based vaccines and increasing integration of advanced equipment in the clinical laboratories |
Low Pressure Liquid Chromatography Market Highlights:
Frequently Asked Questions (FAQ) :
The Low-Pressure Liquid Chromatography market size was valued at USD 5.9 Billion in 2023.
The market is projected to grow at a CAGR of 6.40% during the forecast period, 2024-2032.
North America had the largest share in the market
The key players in the market are Novasep, LEWA GmbH, Biolinx Labsystems, Bio-Rad Laboratories Inc., Danaher Corporation, and Nilsan Nishotech Systems Pvt. Ltd.
The Instruments Component dominated the market in 2023.
The Pharmaceutical Companies End User had the largest share in the market.
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Research Analyst Level I He is an extremely curious individual currently working in healthcare and medical devices domain. kinjoll is comfortably versed in data centric research backed by healthcare educational background. he leverages extensive data mining and analytics tools such as primary and secondary research, statistical analysis, machine learning, data modelling. his key role also involves technical sales support, client interaction and project management within the healthcare team. lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.
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