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    Joint Pain Injection Market

    ID: MRFR/HC/30900-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Joint Pain Injection Market Research Report By Product Type (Corticosteroids, Hyaluronic Acid, PRP, Biologics, Stem Cell Therapy), By Injection Type (Intra-articular, Intradermal, Subcutaneous), By Application (Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Tendinitis), By End User (Hospitals, Ambulatory Surgical Centers, Physiotherapy Clinics) and  By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Joint Pain Injection Market Infographic
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    Joint Pain Injection Market Summary

    As per MRFR analysis, the Joint Pain Injection Market Size was estimated at 4.756 USD Billion in 2024. The Joint Pain Injection industry is projected to grow from 5.005 USD Billion in 2025 to 8.343 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.24 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Joint Pain Injection Market is experiencing a transformative shift towards non-surgical and personalized treatment options.

    • The market is witnessing a rising demand for non-surgical treatments, particularly in North America, which remains the largest market.
    • Advancements in injection techniques are enhancing the efficacy and safety of joint pain therapies, especially in the Asia-Pacific region, the fastest-growing market.
    • There is a notable focus on personalized medicine, with corticosteroids being the largest segment while PRP and hyaluronic acid are rapidly gaining traction.
    • Key market drivers include the increasing prevalence of joint disorders and a growing investment in healthcare infrastructure, which are propelling the adoption of injection therapies.

    Market Size & Forecast

    2024 Market Size 4.756 (USD Billion)
    2035 Market Size 8.343 (USD Billion)
    CAGR (2025 - 2035) 5.24%

    Major Players

    Pfizer (US), Johnson & Johnson (US), Sanofi (FR), Bristol-Myers Squibb (US), Amgen (US), Hyaluronic Acid (DE), Mylan (US), Stryker (US), Regeneron Pharmaceuticals (US)

    Joint Pain Injection Market Trends

    The Joint Pain Injection Market is currently experiencing a notable evolution, driven by a combination of factors including an aging population and increasing prevalence of musculoskeletal disorders. As individuals seek effective pain management solutions, the demand for injectable treatments appears to be on the rise. This market encompasses a variety of products, including corticosteroids, hyaluronic acid, and biologics, each offering distinct benefits for patients suffering from joint pain. The growing awareness of these treatment options, alongside advancements in injection techniques, suggests a shift towards more patient-centric approaches in managing joint-related ailments. Moreover, the Joint Pain Injection Market is likely to witness innovations in product formulations and delivery methods. Research and development efforts are focusing on enhancing the efficacy and safety profiles of these injections, which may lead to improved patient outcomes. Additionally, the integration of telemedicine and digital health solutions could facilitate better access to these treatments, particularly in underserved regions. As healthcare providers continue to adapt to changing patient needs, the market dynamics are expected to evolve, potentially reshaping the landscape of joint pain management in the coming years.

    Rising Demand for Non-Surgical Treatments

    The Joint Pain Injection Market is seeing an increasing preference for non-surgical interventions. Patients are often seeking alternatives to invasive procedures, which may lead to a higher adoption of injectable therapies. This trend indicates a shift in patient attitudes towards managing joint pain, favoring less invasive options that promise quicker recovery times.

    Advancements in Injection Techniques

    Innovations in injection methodologies are transforming the Joint Pain Injection Market. Enhanced techniques, such as ultrasound-guided injections, are improving accuracy and effectiveness. These advancements not only increase patient comfort but also contribute to better clinical outcomes, thereby influencing the overall market growth.

    Focus on Personalized Medicine

    The trend towards personalized medicine is becoming increasingly relevant within the Joint Pain Injection Market. Tailoring treatments to individual patient profiles may enhance therapeutic efficacy. This approach reflects a broader movement in healthcare, emphasizing the importance of customized treatment plans to address specific patient needs.

    The increasing prevalence of joint disorders and the rising demand for minimally invasive treatment options are driving innovation and growth in the global joint pain injection market.

    U.S. National Institutes of Health

    Joint Pain Injection Market Drivers

    Increasing Prevalence of Joint Disorders

    The rising incidence of joint disorders, such as osteoarthritis and rheumatoid arthritis, is a primary driver of the Joint Pain Injection Market. According to recent estimates, millions of individuals are affected by these conditions, leading to a growing demand for effective treatment options. As the population ages, the prevalence of joint-related ailments is expected to escalate, further propelling the market. The Joint Pain Injection Market is likely to benefit from this trend, as patients seek alternatives to traditional pain management methods. This increasing prevalence not only highlights the need for innovative therapies but also underscores the importance of timely interventions to improve patients' quality of life. Consequently, healthcare providers are increasingly turning to injection therapies as a viable solution, thereby expanding the market's potential.

    Shift Towards Minimally Invasive Procedures

    The ongoing shift towards minimally invasive procedures is reshaping the Joint Pain Injection Market. Patients increasingly prefer treatments that offer quicker recovery times and reduced risks compared to traditional surgical options. Injection therapies, which are often performed on an outpatient basis, align well with this preference. As a result, there is a growing trend among healthcare providers to adopt injection therapies as a primary method for managing joint pain. This shift not only enhances patient satisfaction but also reduces the overall burden on healthcare systems. The Joint Pain Injection Market is likely to experience growth as more patients opt for these less invasive alternatives, leading to an increase in the adoption of injection therapies across various healthcare settings.

    Growing Investment in Healthcare Infrastructure

    The expansion of healthcare infrastructure is a significant driver of the Joint Pain Injection Market. Increased investment in healthcare facilities, particularly in emerging markets, is enhancing access to advanced treatment options, including joint pain injections. As hospitals and clinics upgrade their capabilities, they are more likely to offer a wider range of injection therapies to meet patient needs. This trend is particularly evident in regions where healthcare access has historically been limited. The Joint Pain Injection Market is poised to benefit from this growth, as improved infrastructure facilitates the delivery of innovative treatments. Furthermore, as healthcare systems evolve, there is a greater emphasis on integrating advanced pain management solutions, which will likely bolster the market.

    Technological Advancements in Injection Therapies

    Technological innovations in injection therapies are significantly influencing the Joint Pain Injection Market. Recent advancements, such as the development of ultrasound-guided injections and improved needle designs, enhance the precision and efficacy of treatments. These innovations not only minimize patient discomfort but also increase the success rates of injections. Furthermore, the introduction of biologics and regenerative medicine techniques, such as platelet-rich plasma (PRP) injections, is transforming the landscape of joint pain management. As these technologies continue to evolve, they are expected to attract more patients seeking effective and less invasive treatment options. The Joint Pain Injection Market stands to gain from these advancements, as they align with the growing demand for safer and more effective therapies.

    Rising Awareness and Acceptance of Injection Treatments

    There is a notable increase in awareness and acceptance of injection treatments among patients and healthcare professionals, which is driving the Joint Pain Injection Market. Educational initiatives and marketing campaigns have played a crucial role in informing patients about the benefits of injection therapies, such as corticosteroids and hyaluronic acid injections. As more individuals become aware of these options, the demand for such treatments is likely to rise. Additionally, healthcare providers are increasingly recommending injection therapies as first-line treatments for joint pain, further solidifying their role in pain management. This shift in perception is expected to contribute to the growth of the Joint Pain Injection Market, as more patients seek out these effective solutions.

    Market Segment Insights

    By Product Type: Corticosteroids (Largest) vs. Hyaluronic Acid, PRP (Fastest-Growing)

    In the Joint Pain Injection Market, corticosteroids represent the largest segment, widely recognized for their anti-inflammatory properties and effectiveness in treating various joint pains. Following closely are hyaluronic acid injections and platelet-rich plasma (PRP), which are gaining traction due to their promising outcomes in joint health and pain management. Meanwhile, biologics and stem cell therapies are emerging segments, showing moderate market presence but a growing interest, particularly in chronic joint conditions.

    Corticosteroids (Dominant) vs. Hyaluronic Acid, PRP (Emerging)

    Corticosteroids have established themselves as the dominant choice in joint pain management, primarily due to their rapid action and effectiveness in reducing inflammation. They are widely used in treatments for arthritis and injuries, making them the go-to option for many healthcare providers. In contrast, hyaluronic acid and PRP therapies represent an emerging trend in the market, focusing on more holistic and regenerative approaches. These treatments appeal to patients seeking alternatives to traditional steroid injections, especially as they are perceived to have fewer side effects and promote natural healing processes. As these emerging treatments gain popularity, they are likely to significantly influence the future landscape of joint pain management.

    By Injection Type: Intra-articular (Largest) vs. Subcutaneous (Fastest-Growing)

    In the Joint Pain Injection Market, the Intra-articular injection type currently holds the largest market share due to its widespread use and effectiveness in delivering medication directly into the joint space, providing targeted pain relief. Following this, the Subcutaneous injection is also gaining traction, appealing to patients for its ease of administration, which allows individuals to self-administer medications at home, thereby enhancing adherence to treatment protocols.

    Intra-articular (Dominant) vs. Subcutaneous (Emerging)

    The Intra-articular segment is the dominant force in the Joint Pain Injection Market, recognized for its direct approach in treating localized pain by injecting steroids or hyaluronic acid directly into the affected joint. Its efficacy in alleviating pain and improving joint function makes it a preferred choice among healthcare professionals. In contrast, the Subcutaneous segment is emerging rapidly, particularly due to innovations in biologic therapies that allow for self-injection. This method is less invasive and offers greater convenience for patients, which contributes to its increasing popularity as a viable alternative for managing chronic joint pain.

    By Application: Osteoarthritis (Largest) vs. Tendinitis (Fastest-Growing)

    The Joint Pain Injection Market is characterized by a diverse array of applications, including osteoarthritis, rheumatoid arthritis, post-traumatic arthritis, and tendinitis. Among these, osteoarthritis stands out as the largest segment, capturing a significant portion of the market share. This dominance is principally due to the high prevalence of osteoarthritis among the aging population, coupled with a growing demand for effective pain management solutions. Meanwhile, tendinitis is emerging as the fastest-growing segment, driven by increasing participation in sports and physical activities that heighten the risk of tendon injuries.

    Osteoarthritis: Dominant vs. Tendinitis: Emerging

    Osteoarthritis represents the dominant application within the Joint Pain Injection Market, primarily due to its widespread incidence and the chronic nature of the condition. Patients suffering from osteoarthritis often seek long-term relief through joint injections, making this segment critical for healthcare providers. Conversely, tendinitis is rapidly emerging, reflecting trends in active lifestyles and sports-related injuries. As more individuals engage in physical fitness and competitive sports, the incidence of tendinitis has surged, leading to a demand for innovative injection therapies. This shift illustrates a changing landscape where both segments play crucial roles in addressing joint-related pain, catering to different patient needs and treatment approaches.

    By End User: Hospitals (Largest) vs. Ambulatory Surgical Centers (Fastest-Growing)

    In the Joint Pain Injection Market, hospitals hold the largest market share, leveraging their advanced medical infrastructure and comprehensive patient care services. This segment is widely favored for its ability to provide complex, multi-disciplinary approaches to joint pain management, which includes surgical interventions and post-operative injections. Ambulatory surgical centers (ASCs) are gaining traction as they offer a convenient and cost-effective alternative for joint pain injections, catering to the increasing preference for outpatient procedures. As the healthcare landscape evolves, these centers are becoming a pivotal part of the treatment paradigm, particularly for less invasive procedures and rapid recovery processes.

    Hospitals (Dominant) vs. Ambulatory Surgical Centers (Emerging)

    Hospitals remain the dominant force in the Joint Pain Injection Market, primarily due to their extensive resources, specialization, and ability to handle a wide range of complex cases. They provide a comprehensive setting where patients can receive various treatments under one roof, ensuring high-quality care and oversight during procedures. In contrast, ambulatory surgical centers are emerging as a popular choice for patients seeking faster, outpatient solutions for joint pain injections. These centers excel in providing a streamlined, focused approach to treatment, often leading to shorter wait times and reduced overall treatment costs. The convenience and efficiency of ASCs continue to attract patients, positioning them as a crucial player in the expanding joint pain injection landscape.

    Get more detailed insights about Joint Pain Injection Market

    Regional Insights

    North America : Market Leader in Innovation

    North America is the largest market for joint pain injections, accounting for approximately 45% of the global market share. The region's growth is driven by an aging population, increasing prevalence of joint disorders, and advancements in injection technologies. Regulatory support from agencies like the FDA has also catalyzed market expansion, facilitating quicker approvals for innovative treatments. The United States is the primary contributor, with key players such as Pfizer, Johnson & Johnson, and Amgen leading the competitive landscape. The presence of advanced healthcare infrastructure and high healthcare expenditure further enhances market dynamics. Canada also plays a significant role, contributing to the overall growth with its supportive healthcare policies and increasing adoption of joint pain injection therapies.

    Europe : Emerging Market with Growth Potential

    Europe is the second-largest market for joint pain injections, holding around 30% of the global market share. The region's growth is propelled by rising healthcare awareness, increasing geriatric population, and favorable reimbursement policies. Regulatory bodies like the European Medicines Agency (EMA) are actively promoting innovative therapies, which is expected to enhance market accessibility and patient outcomes. Leading countries include Germany, France, and the UK, where major players like Sanofi and Bristol-Myers Squibb are well-established. The competitive landscape is characterized by a mix of multinational corporations and local firms, fostering innovation and collaboration. The increasing prevalence of osteoarthritis and rheumatoid arthritis further drives demand for effective joint pain management solutions.

    Asia-Pacific : Rapidly Growing Market Segment

    Asia-Pacific is witnessing rapid growth in the joint pain injection market, accounting for approximately 20% of the global share. Factors such as rising disposable incomes, increasing awareness of joint health, and a growing elderly population are driving demand. Countries like China and India are experiencing significant market expansion due to their large patient populations and improving healthcare infrastructure. China is the largest market in the region, with a burgeoning demand for advanced medical treatments. The competitive landscape includes both local and international players, with companies like Mylan and Stryker making significant inroads. The region's regulatory environment is evolving, with governments focusing on enhancing healthcare access and affordability, further propelling market growth.

    Middle East and Africa : Untapped Market with Potential

    The Middle East and Africa represent an emerging market for joint pain injections, holding about 5% of the global market share. The region's growth is driven by increasing healthcare investments, rising prevalence of joint disorders, and a growing awareness of treatment options. Countries like South Africa and the UAE are leading the way, with governments focusing on improving healthcare infrastructure and access to advanced medical treatments. The competitive landscape is still developing, with a mix of local and international players entering the market. Key players are beginning to establish a presence, and partnerships with healthcare providers are becoming more common. The region's unique demographic trends and increasing healthcare expenditure present significant opportunities for growth in the joint pain injection market.

    Key Players and Competitive Insights

    The Joint Pain Injection Market is currently characterized by a dynamic competitive landscape, driven by increasing demand for effective pain management solutions and advancements in injection technologies. Key players such as Pfizer (US), Johnson & Johnson (US), and Amgen (US) are strategically positioned to leverage their extensive research and development capabilities, focusing on innovative therapies and expanding their product portfolios. These companies are actively pursuing partnerships and collaborations to enhance their market presence, thereby shaping a competitive environment that emphasizes both innovation and accessibility.

    In terms of business tactics, companies are increasingly localizing manufacturing to reduce costs and improve supply chain efficiency. The market appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies like Bristol-Myers Squibb (US) and Sanofi (FR) suggests a trend towards consolidation, as these firms seek to optimize their operations and enhance their competitive edge through strategic mergers and acquisitions.

    In August 2025, Pfizer (US) announced a collaboration with a leading biotechnology firm to develop a novel joint pain injection therapy that utilizes advanced biomaterials. This strategic move is likely to enhance Pfizer's product offerings and position the company as a leader in innovative pain management solutions. The partnership underscores the importance of leveraging external expertise to accelerate the development of cutting-edge therapies in a competitive market.

    Similarly, in September 2025, Johnson & Johnson (US) launched a new digital platform aimed at improving patient engagement and education regarding joint pain management. This initiative reflects a growing trend towards digital transformation in healthcare, as companies recognize the need to empower patients with information and resources. By enhancing patient experience, Johnson & Johnson may strengthen its brand loyalty and market position.

    In October 2025, Amgen (US) revealed plans to expand its manufacturing capabilities in Europe, focusing on the production of its joint pain injection products. This expansion is indicative of Amgen's commitment to meeting the rising demand for its therapies while ensuring supply chain reliability. Such strategic investments are crucial for maintaining a competitive advantage in a market that is increasingly reliant on efficient production and distribution networks.

    As of October 2025, the Joint Pain Injection Market is witnessing significant trends such as digitalization, sustainability, and the integration of artificial intelligence in product development. Strategic alliances are becoming increasingly important, as companies collaborate to enhance their technological capabilities and market reach. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition towards a focus on innovation, technological advancements, and the reliability of supply chains. This shift may redefine the competitive landscape, compelling companies to prioritize research and development to stay ahead in a rapidly changing market.

    Key Companies in the Joint Pain Injection Market market include

    Industry Developments

    • Q2 2024: Bioventus Announces FDA Clearance of GENESIS™ Autologous Protein Solution for the Treatment of Knee Osteoarthritis Bioventus received FDA clearance for its GENESIS™ Autologous Protein Solution, a new injectable therapy for knee osteoarthritis, expanding its portfolio in the joint pain injection market.
    • Q2 2024: OrthogenRx Announces Launch of TriVisc® Single Injection Hyaluronic Acid for Osteoarthritis Knee Pain OrthogenRx launched TriVisc®, a single-injection hyaluronic acid product for knee osteoarthritis pain, marking a new product entry in the joint pain injection sector.
    • Q2 2024: Anika Announces FDA Clearance of Integrity™ Implant for Joint Pain Management Anika Therapeutics received FDA clearance for its Integrity™ implant, designed for joint pain management, strengthening its position in the orthopedic injection market.
    • Q3 2024: Sanofi and Regeneron Announce Expanded Partnership to Develop Injectable Therapies for Osteoarthritis Sanofi and Regeneron expanded their partnership to co-develop new injectable biologic therapies targeting osteoarthritis, aiming to advance joint pain treatment options.
    • Q3 2024: Zimmer Biomet Launches Next-Generation Gel-One® Hyaluronate Injection for Knee Osteoarthritis Zimmer Biomet launched its next-generation Gel-One® Hyaluronate injection, offering improved pain relief for patients with knee osteoarthritis.
    • Q4 2024: Flexion Therapeutics Announces FDA Approval of Zilretta® for Expanded Indication in Hip Osteoarthritis Flexion Therapeutics received FDA approval for Zilretta® to treat hip osteoarthritis, expanding the product's indications in the joint pain injection market.
    • Q4 2024: Seikagaku Corporation Receives FDA Approval for SI-613 Injectable for Knee Osteoarthritis Seikagaku Corporation received FDA approval for SI-613, a new injectable therapy for knee osteoarthritis, enhancing its U.S. market presence.
    • Q1 2025: Fidia Pharma Launches Hyalubrix® Plus Single Injection for Joint Pain Relief in Europe Fidia Pharma launched Hyalubrix® Plus, a single-injection hyaluronic acid product for joint pain relief, expanding its European product portfolio.
    • Q1 2025: Bioventus Announces Acquisition of CartiHeal, Expanding Joint Pain Injection Portfolio Bioventus acquired CartiHeal, a company specializing in injectable therapies for joint pain, strengthening its market position and product offerings.
    • Q2 2025: Smith & Nephew Opens New Manufacturing Facility for Injectable Orthopedic Products in Texas Smith & Nephew opened a new manufacturing facility in Texas dedicated to producing injectable orthopedic products, including joint pain injections.
    • Q2 2025: Anika Therapeutics Announces CE Mark Approval for Hyalofast® Injectable Scaffold for Cartilage Repair Anika Therapeutics received CE Mark approval for Hyalofast®, an injectable scaffold for cartilage repair, expanding its joint pain treatment options in Europe.
    • Q3 2025: Flexion Therapeutics Secures $75 Million Series C Funding to Advance Injectable Pain Therapies Flexion Therapeutics raised $75 million in Series C funding to support the development and commercialization of new injectable therapies for joint pain.

    Future Outlook

    Joint Pain Injection Market Future Outlook

    The Joint Pain Injection Market is projected to grow at a 5.24% CAGR from 2024 to 2035, driven by increasing prevalence of joint disorders, advancements in injection technologies, and rising demand for minimally invasive treatments.

    New opportunities lie in:

    • Development of personalized injection therapies targeting specific joint conditions.
    • Expansion of telehealth services for remote consultation and injection management.
    • Partnerships with orthopedic clinics for integrated pain management solutions.

    By 2035, the Joint Pain Injection Market is expected to be robust, reflecting significant advancements and increased accessibility.

    Market Segmentation

    Joint Pain Injection Market End User Outlook

    • Hospitals
    • Ambulatory Surgical Centers
    • Physiotherapy Clinics

    Joint Pain Injection Market Application Outlook

    • Osteoarthritis
    • Rheumatoid Arthritis
    • Post-traumatic Arthritis
    • Tendinitis

    Joint Pain Injection Market Product Type Outlook

    • Corticosteroids
    • Hyaluronic Acid, PRP
    • Biologics
    • Stem Cell Therapy

    Joint Pain Injection Market Injection Type Outlook

    • Intra-articular
    • Intradermal
    • Subcutaneous

    Report Scope

    MARKET SIZE 20244.756(USD Billion)
    MARKET SIZE 20255.005(USD Billion)
    MARKET SIZE 20358.343(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)5.24% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesEmergence of innovative biologics and personalized therapies in the Joint Pain Injection Market.
    Key Market DynamicsRising demand for minimally invasive treatments drives innovation and competition in the joint pain injection market.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

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    FAQs

    What is the projected market valuation of the Joint Pain Injection Market by 2035?

    The Joint Pain Injection Market is projected to reach a valuation of 8.343 USD Billion by 2035.

    What was the market valuation of the Joint Pain Injection Market in 2024?

    In 2024, the Joint Pain Injection Market was valued at 4.756 USD Billion.

    What is the expected CAGR for the Joint Pain Injection Market during the forecast period 2025 - 2035?

    The expected CAGR for the Joint Pain Injection Market during the forecast period 2025 - 2035 is 5.24%.

    Which product type segment is anticipated to show significant growth in the Joint Pain Injection Market?

    The Stem Cell Therapy segment is anticipated to grow from 1.056 USD Billion in 2024 to 2.343 USD Billion by 2035.

    What are the key players in the Joint Pain Injection Market?

    Key players in the Joint Pain Injection Market include Pfizer, Johnson & Johnson, Sanofi, and Bristol-Myers Squibb.

    Which injection type segment is expected to have the highest valuation by 2035?

    The Intra-articular injection type segment is expected to reach a valuation of 3.978 USD Billion by 2035.

    What application segment is projected to grow the most in the Joint Pain Injection Market?

    The Tendinitis application segment is projected to grow from 1.156 USD Billion in 2024 to 2.343 USD Billion by 2035.

    How does the market valuation of hospitals compare to other end users in 2035?

    By 2035, the market valuation for hospitals is expected to be 3.305 USD Billion, surpassing other end users.

    What is the growth trend for the Hyaluronic Acid, PRP product type segment?

    The Hyaluronic Acid, PRP segment is expected to grow from 1.2 USD Billion in 2024 to 2.0 USD Billion by 2035.

    Which end user segment is projected to show the least growth by 2035?

    The Ambulatory Surgical Centers segment is projected to show the least growth, reaching 2.469 USD Billion by 2035.

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