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Italy Drug Repurposing Market

ID: MRFR/Pharma/50634-HCR
200 Pages
Rahul Gotadki
October 2025

Italy Drug Repurposing Market Research Report: Size, Share, Trend Analysis By Typess (Disease-centric, Target-centric, Drug-centric), By Therapeutic Area (Same Therapeutic Area, Different Therapeutic Area) and By Drug Molecules (Biologics, Small Molecule) - Growth Outlook & Industry Forecast 2025 To 2035

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Italy Drug Repurposing Market Infographic
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Italy Drug Repurposing Market Summary

As per Market Research Future analysis, the Italy Drug Repurposing Market size was estimated at 14.0 USD Million in 2024. The Drug Repurposing market is projected to grow from 16.1 USD Million in 2025 to 65.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 14.9% during the forecast period 2025 - 2035

Key Market Trends & Highlights

The Italy drug repurposing market is poised for growth driven by collaboration and regulatory support.

  • The market is witnessing increased collaboration between pharmaceutical companies and research institutions to enhance drug repurposing efforts.
  • Regulatory support for repurposing initiatives is becoming more pronounced, facilitating faster approval processes.
  • Technological advancements in drug discovery are enabling more efficient identification of potential repurposing candidates.
  • Key market drivers include rising healthcare costs and an aging population, which are fueling the demand for innovative treatment solutions.

Market Size & Forecast

2024 Market Size 14.0 (USD Million)
2035 Market Size 65.0 (USD Million)
CAGR (2025 - 2035) 14.98%

Major Players

Novartis (CH), Pfizer (US), Bristol-Myers Squibb (US), Johnson & Johnson (US), AstraZeneca (GB), Eli Lilly and Company (US), Sanofi (FR), GSK (GB), Amgen (US)

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Italy Drug Repurposing Market Trends

The Italy Drug Repurposing Market is currently experiencing notable growth, driven by the increasing need for cost-effective therapeutic solutions. In Italy, the healthcare system is under pressure to provide innovative treatments while managing budget constraints. This has led to a heightened interest in repurposing existing drugs, which can significantly reduce development time and costs compared to traditional drug discovery. Furthermore, regulatory bodies in Italy are becoming more supportive of repurposing initiatives, recognizing their potential to address unmet medical needs efficiently. As a result, pharmaceutical companies are increasingly exploring this avenue, leading to a surge in collaborations between academia and industry. Moreover, the landscape of the drug repurposing market is evolving with advancements in technology and data analytics. The integration of artificial intelligence and machine learning is enhancing the ability to identify new therapeutic uses for existing medications. In Italy, research institutions are leveraging these technologies to analyze vast datasets, which may uncover novel applications for established drugs. This trend not only accelerates the repurposing process but also fosters innovation within the healthcare sector. Overall, the drug repurposing market appears poised for continued expansion, driven by economic factors and technological advancements that align with the needs of the Italian healthcare system.

Increased Collaboration Between Sectors

There is a growing trend of collaboration between pharmaceutical companies, academic institutions, and government agencies in Italy. This synergy aims to facilitate the identification and development of new therapeutic uses for existing drugs. Such partnerships are likely to enhance research capabilities and streamline the repurposing process, ultimately benefiting patients.

Regulatory Support for Repurposing Initiatives

Italian regulatory bodies are increasingly recognizing the value of drug repurposing as a viable strategy for addressing public health challenges. This support may manifest in streamlined approval processes and incentives for companies pursuing repurposing projects, thereby encouraging innovation and investment in this area.

Technological Advancements in Drug Discovery

The integration of advanced technologies, such as artificial intelligence and big data analytics, is transforming the drug repurposing market. In Italy, these innovations are enabling researchers to analyze complex datasets more effectively, potentially leading to the discovery of new applications for existing medications and expediting the repurposing process.

Italy Drug Repurposing Market Drivers

Aging Population

Italy's demographic shift towards an aging population is significantly impacting the drug repurposing market. With a growing proportion of elderly individuals, there is an increasing prevalence of chronic diseases that require innovative treatment options. Drug repurposing presents an opportunity to quickly provide effective therapies for age-related conditions, leveraging existing medications that may have untapped potential. The Italian National Institute of Statistics reported that by 2025, over 23% of the population will be aged 65 and older. This demographic trend suggests a rising demand for repurposed drugs that can address the specific health challenges faced by older adults. Consequently, the drug repurposing market is likely to expand as pharmaceutical companies and researchers focus on developing solutions tailored to this demographic.

Rising Healthcare Costs

The escalating costs associated with healthcare in Italy are driving interest in the drug repurposing market. As healthcare expenditures continue to rise, stakeholders are increasingly seeking cost-effective solutions to address unmet medical needs. Drug repurposing offers a viable pathway to reduce development costs, as existing drugs can be utilized for new therapeutic indications. This approach not only shortens the time to market but also minimizes the financial burden on healthcare systems. In Italy, where healthcare spending reached approximately €200 billion in 2023, the potential for repurposed drugs to alleviate some of these costs is becoming more apparent. The drug repurposing market is thus positioned to play a crucial role in enhancing the efficiency of healthcare delivery while addressing the financial constraints faced by the Italian healthcare system.

Increased Focus on Rare Diseases

The growing emphasis on rare diseases in Italy is fostering a conducive environment for the drug repurposing market. With approximately 7,000 rare diseases affecting millions of Italians, there is a pressing need for effective treatments. Drug repurposing allows for the rapid identification of existing drugs that may be effective for these conditions, thus accelerating the development of therapies. The Italian Medicines Agency has been actively promoting initiatives to support research in this area, which could lead to a surge in repurposed drugs targeting rare diseases. As the market for rare disease treatments is projected to reach €20 billion by 2026, the drug repurposing market is likely to benefit from this trend, providing innovative solutions for patients with limited options.

Regulatory Incentives for Innovation

The regulatory landscape in Italy is becoming increasingly favorable for the drug repurposing market. Authorities are implementing incentives to encourage innovation and expedite the approval process for repurposed drugs. These regulatory frameworks aim to streamline the pathway for bringing new therapies to market, particularly for conditions with high unmet medical needs. The Italian Medicines Agency has introduced measures that facilitate faster evaluations and approvals for repurposed drugs, which could significantly enhance their market entry. As a result, pharmaceutical companies are more likely to invest in drug repurposing initiatives, recognizing the potential for quicker returns on investment. This supportive regulatory environment is expected to drive growth in the drug repurposing market, ultimately benefiting patients in need of effective treatments.

Advancements in Research Collaboration

The landscape of research collaboration in Italy is evolving, which is positively influencing the drug repurposing market. Academic institutions, pharmaceutical companies, and research organizations are increasingly partnering to explore new therapeutic uses for existing drugs. This collaborative approach enhances the sharing of knowledge and resources, facilitating the identification of promising repurposing opportunities. In recent years, several public-private partnerships have emerged, focusing on drug repurposing initiatives. These collaborations not only expedite the research process but also attract funding, which is crucial for advancing projects in the drug repurposing market. As Italy continues to foster a culture of collaboration, the potential for innovative repurposed therapies is likely to grow, benefiting both patients and the healthcare system.

Market Segment Insights

By Type: Target-centric (Largest) vs. Disease-centric (Fastest-Growing)

In the Italy drug repurposing market, the distribution of market share among segment values reveals that the Target-centric approach is currently the largest, leveraging robust pipelines and contributions from well-established pharmaceutical companies. This segment thrives on a strategic alignment between drug action and biological targets, fostering a more effective and tailored approach in repurposing existing medications, thus maximizing therapeutic benefits for various diseases. Meanwhile, the Disease-centric segment is experiencing rapid growth and is recognized as the fastest-growing in this space. This approach emphasizes the specific conditions being treated, enabling targeted solutions that resonate with current healthcare priorities and patient needs. Factors driving this growth include heightened awareness of personalized medicine and advancements in research methodologies that support innovative therapy development.

Target-centric (Dominant) vs. Disease-centric (Emerging)

The Target-centric approach in the Italy drug repurposing market stands out as a dominant force, characterized by its focus on specific biological targets to enhance drug efficacy. This segment benefits from significant investments and collaborative efforts between biotech firms and academic institutions, ensuring a steady influx of innovative repurposed treatments that address unmet medical needs. Conversely, the Disease-centric approach is emerging rapidly, driven by an increasing demand for therapies targeting prevalent diseases. This segment encourages a deeper understanding of disease mechanisms, allowing researchers to adapt existing drugs effectively. As both segments are pivotal to advancing therapeutic strategies, they showcase the dynamic nature of drug repurposing efforts in Italy.

By Therapeutic Area: Same Therapeutic Area (Largest) vs. Different Therapeutic Area (Fastest-Growing)

In the Italy drug repurposing market, the distribution of market share indicates that the 'Same Therapeutic Area' segment holds the largest portion, reflecting its established methods and existing drug frameworks. This segment is well-supported by ongoing research and successful case studies that showcase the effectiveness of repurposed drugs within the same therapeutic indications, resulting in a stable market share position. Conversely, the 'Different Therapeutic Area' segment is identified as the fastest-growing segment, driven by innovative approaches and increasing regulatory support for drug repurposing initiatives. Factors contributing to this growth include advancements in biotechnology, collaborations between academic institutions and pharmaceutical companies, and the urgent need for alternative therapies, particularly in challenging disease areas, justifying the rising interest and investment in this segment.

Same Therapeutic Area: Dominant vs. Different Therapeutic Area: Emerging

The 'Same Therapeutic Area' segment represents a dominant force in the Italy drug repurposing market, benefiting from established relationships and extensive data on pre-existing drugs, allowing for quicker regulatory approval processes. Its strength lies in proven efficacy within known therapeutic frameworks. On the other hand, the 'Different Therapeutic Area' segment is seen as an emerging powerhouse, exploring fresh paths for drug application, fueled by innovative research and the potential for breakthrough discoveries. This segment is characterized by a dynamic approach that seeks to address unmet medical needs and foster collaborations across various scientific disciplines, ultimately accelerating the delivery of new treatment options to the market.

By Drug Molecules: Biologics (Largest) vs. Small Molecule (Fastest-Growing)

In the Italy drug repurposing market, Biologics holds a significant portion of the market share due to its efficacy and demand in treating chronic diseases. This segment benefits from advancements in biotechnology that enable the development of more effective therapeutic options. Small Molecule drugs, although currently a smaller segment, are rapidly gaining traction as they offer unique advantages such as cheaper manufacturing and ease of administration. The growth trends in this segment are driven by increasing research and development investments aimed at repurposing existing drugs for new therapeutic applications. Biologics is experiencing robust growth as more institutions recognize their potential, while Small Molecules are emerging rapidly, appealing to healthcare providers for their versatility and cost-effectiveness. Collaborations between pharmaceutical companies and research organizations further fuel this growth, enhancing development efficiencies.

Biologics (Dominant) vs. Small Molecule (Emerging)

Biologics are recognized as the dominant force in the Italy drug repurposing market due to their capacity to provide targeted therapies and improved patient outcomes. These products, including monoclonal antibodies and vaccines, have been pivotal in addressing complex health issues. Their development is often supported by substantial clinical evidence and regulatory backing, making them favored choices among healthcare providers. Small Molecules, while currently an emerging segment, benefit from a lower cost of production and simpler delivery mechanisms, appealing to both patients and healthcare systems. The flexibility of Small Molecules in being rapidly altered and optimized for specific conditions can accelerate the drug repurposing process, positioning them as a vital complement to Biologics in enhancing treatment options.

Get more detailed insights about Italy Drug Repurposing Market

Key Players and Competitive Insights

The drug repurposing market in Italy is characterized by a dynamic competitive landscape, driven by the increasing need for cost-effective therapeutic solutions and the rising prevalence of chronic diseases. Major players such as Novartis (CH), Pfizer (US), and AstraZeneca (GB) are actively engaged in innovative strategies that emphasize research and development, partnerships, and digital transformation. These companies are not only focusing on repurposing existing drugs to address unmet medical needs but are also leveraging their extensive pipelines to enhance their market positions. The collective efforts of these firms contribute to a moderately fragmented market structure, where collaboration and strategic alliances play a crucial role in shaping competitive dynamics.Key business tactics employed by these companies include localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The competitive structure of the market appears to be moderately fragmented, with several key players exerting influence through their established reputations and innovative capabilities. This fragmentation allows for a diverse range of therapeutic options, although it also necessitates a keen focus on differentiation strategies to maintain competitive advantage.

In October Novartis (CH) announced a strategic partnership with a leading Italian biotech firm to explore the repurposing of existing therapies for rare diseases. This collaboration is expected to accelerate the development of novel treatment options, thereby enhancing Novartis's portfolio and reinforcing its commitment to addressing niche markets. The strategic importance of this partnership lies in its potential to leverage local expertise and resources, which may lead to faster clinical trials and regulatory approvals.

In September Pfizer (US) launched a new initiative aimed at repurposing its existing oncology drugs for the treatment of autoimmune diseases. This move reflects Pfizer's adaptive strategy to diversify its therapeutic offerings and respond to emerging healthcare needs. The significance of this initiative is underscored by the growing demand for innovative treatments in the autoimmune sector, positioning Pfizer as a proactive player in a rapidly evolving market.

In August AstraZeneca (GB) expanded its research efforts in collaboration with Italian universities to investigate the potential of repurposing cardiovascular drugs for neurodegenerative conditions. This strategic action highlights AstraZeneca's commitment to harnessing academic partnerships to drive innovation. The implications of this collaboration are profound, as it may lead to breakthroughs in treatment options for conditions that currently lack effective therapies.

As of November current competitive trends in the drug repurposing market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) in research processes. Strategic alliances are becoming more prevalent, enabling companies to pool resources and expertise to accelerate drug development. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize these areas will be better positioned to thrive in an increasingly complex and competitive landscape.

Key Companies in the Italy Drug Repurposing Market include

Industry Developments

In recent months, the Italy Drug Repurposing Market has seen significant developments, particularly in the realm of innovative treatments and therapies being explored by major pharmaceutical companies, including AstraZeneca, Roche, Merck and Co, and others. For example, AstraZeneca has made strides in utilizing existing drugs for alternative therapies, particularly related to oncology and cardiovascular diseases. Notably, Roche has been actively involved in research studies to repurpose antiviral drugs for COVID-19 treatments. 

In early 2023, Merck and Co. announced a new collaboration with Italian research institutions to expedite research in drug repurposing, reflecting Italy's growing importance as a hub for pharmaceutical innovation. Additionally, Acquisitions involving companies like Gilead Sciences could reshape the market landscape as they integrate innovative solutions into their portfolios. 

Over the last couple of years, from August 2021 to October 2023, there has been remarkable growth in drug repurposing initiatives in Italy, with significant government funding allocated to enhance research capacities and collaborations aimed at boosting the local pharmaceutical industry, contributing to the increased valuation of companies operating in this sector.

Future Outlook

Italy Drug Repurposing Market Future Outlook

The Drug Repurposing Market in Italy is poised for growth at 14.98% CAGR from 2025 to 2035, driven by technological advancements and increasing healthcare costs.

New opportunities lie in:

  • Development of AI-driven drug screening platforms
  • Partnerships with biotech firms for clinical trials
  • Expansion of telehealth services for patient monitoring

By 2035, the market is expected to achieve substantial growth and innovation.

Market Segmentation

Italy Drug Repurposing Market Type Outlook

  • Disease-centric
  • Target-centric
  • Drug-centric

Italy Drug Repurposing Market Drug Molecules Outlook

  • Biologics
  • Small Molecule

Italy Drug Repurposing Market Therapeutic Area Outlook

  • Same Therapeutic Area
  • Different Therapeutic Area

Report Scope

MARKET SIZE 2024 14.0(USD Million)
MARKET SIZE 2025 16.1(USD Million)
MARKET SIZE 2035 65.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 14.98% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Novartis (CH), Pfizer (US), Bristol-Myers Squibb (US), Johnson & Johnson (US), AstraZeneca (GB), Eli Lilly and Company (US), Sanofi (FR), GSK (GB), Amgen (US)
Segments Covered Type, Therapeutic Area, Drug Molecules
Key Market Opportunities Emerging technologies enhance drug repurposing efficiency, addressing unmet medical needs in the market.
Key Market Dynamics Rising interest in drug repurposing driven by regulatory support and technological advancements in Italy's pharmaceutical sector.
Countries Covered Italy
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FAQs

What is the expected market size of the Italy Drug Repurposing Market in 2024?

The Italy Drug Repurposing Market is expected to be valued at 11.83 million USD in 2024.

What will be the market size of the Italy Drug Repurposing Market by 2035?

By 2035, the Italy Drug Repurposing Market is anticipated to reach a value of 52.58 million USD.

What is the expected CAGR for the Italy Drug Repurposing Market from 2025 to 2035?

The expected compound annual growth rate for the Italy Drug Repurposing Market from 2025 to 2035 is 14.523%.

Which segment will be the largest in the Italy Drug Repurposing Market in 2024?

The Disease-centric segment is expected to be the largest, valued at 4.5 million USD in 2024.

What is the projected value of the Drug-centric segment in 2035?

The Drug-centric segment is projected to be valued at 16.4 million USD by 2035.

Who are the key players in the Italy Drug Repurposing Market?

Major players in the market include AstraZeneca, Roche, Merck & Co, Amgen, and Bayer among others.

What value will the Target-centric segment hold in 2035?

The Target-centric segment is expected to reach a value of 15.7 million USD by 2035.

What are the growth drivers for the Italy Drug Repurposing Market?

Key growth drivers include advancements in drug discovery and increasing healthcare expenditure.

What challenges does the Italy Drug Repurposing Market face?

Challenges include regulatory hurdles and the complexity of clinical trials for repurposed drugs.

How does the global scenario affect the Italy Drug Repurposing Market?

Current global dynamics may influence investment patterns and innovation speed within the market.

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