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Italy Anti-VEGF Market Research Report: By Product (Eylea, Lucentis, Beovu) and By Disease (Macular Edema, Diabetic Retinopathy, Retinal Vein Occlusion, Age-Related Macular Degeneration)- Forecast to 2035


ID: MRFR/HC/50412-HCR | 200 Pages | Author: Garvit Vyas| May 2025

Italy Anti-VEGF Market Overview


As per MRFR analysis, the Italy Anti-VEGF Market Size was estimated at 836.94 (USD Million) in 2023.The Italy Anti-VEGF Market Industry is expected to grow from 872.93(USD Million) in 2024 to 1,491.59 (USD Million) by 2035. The Italy Anti-VEGF Market CAGR (growth rate) is expected to be around 4.991% during the forecast period (2025 - 2035).


Key Italy Anti-VEGF Market Trends Highlighted


The Italy Anti-VEGF market is undergoing substantial growth, which is primarily due to the rising prevalence of diseases such as diabetic retinopathy and age-related macular degeneration, which are prevalent among the ageing society in Italy. The country's demand for effective anti-VEGF therapies is consistently increasing due to its highest ageing demographic in Europe. In addition, the adoption of these treatments within healthcare systems is being further enhanced by improvements in drug formulations and delivery methods, which are resulting in improved patient outcomes. There are opportunities for pharmaceutical companies to investigate personalized medicine approaches and innovative drug combinations that are specifically designed for Italian patients. Collaborations between pharmaceutical companies and research institutions in Italy have the potential to facilitate the development of novel treatment options. In addition, the regional emphasis on enhancing healthcare accessibility may result in a rise in investment in anti-VEGF therapies in both urban and rural regions of the nation.


A greater emphasis has been placed on the effective management of chronic diseases in Italy as a result of the recent transition to more patient-centric care models. The significance of not only alleviating symptoms but also enhancing the overall quality of life for patients with retinal disorders is underscored by this trend. The market is expected to be further fortified by the Italian government's increased financing to improve healthcare infrastructure and its adoption of supportive policies for innovative drug approval processes.In addition, the adoption of anti-VEGF therapies across various patient demographics in Italy is being facilitated by the increasing awareness among healthcare providers and patients regarding the advantages of timely intervention in ocular diseases.


Italy Anti VEGF Market size


Source: Primary Research, Secondary Research, MRFR Database, and Analyst Review


Italy Anti-VEGF Market Drivers


Increasing Prevalence of Age-Related Macular Degeneration


The rising number of individuals diagnosed with age-related macular degeneration (AMD) is a significant driver for the Italy Anti-VEGF Market Industry. According to the Italian Ministry of Health, the prevalence of AMD among the elderly population is expected to rise to 16% by 2035. This increase can be attributed to an aging population, as demographic data indicates that around 23% of Italy's population will be aged over 65 by 2040. The Italian Ophthalmology Society has also reported an increasing trend in patients seeking treatment for sight-threatening retinal diseases, thus leading to a greater demand for anti-VEGF therapies.Major pharmaceutical companies such as Novartis and Bayer have already recognized this growing need, investing in Research and Development for better treatment options, which is catalyzing market growth in this specific sector.


Advancements in Treatment Modalities


Technological advancements in treatment modalities are significantly propelling the Italy Anti-VEGF Market Industry. The development of new Anti-VEGF agents and delivery methods, including intravitreal injections, has enhanced patient outcomes. Data from the Italian Medicines Agency indicates that the approval of innovative therapies has resulted in a 30% increase in treatment adherence among patients experiencing retinal diseases over the last five years.Established organizations such as the Italian Pharmaceutical Association are working closely with healthcare providers to ensure that cutting-edge treatments become widely available. This effort not only reflects positively on the market but also opens avenues for further innovations, thus driving future growth.


Growing Awareness and Screening Initiatives


Increased awareness and screening initiatives focused on retinal diseases have also emerged as crucial drivers in the Italy Anti-VEGF Market Industry. Campaigns spearheaded by associations like the Italian Retina Society are fostering community education about the importance of early detection and treatment of eye diseases caused by conditions such as diabetes and hypertension. The Italian Health Ministry reports that screening programs have led to a 25% increase in early diagnosis rates of diabetic retinopathy among at-risk populations, contributing significantly to the demand for anti-VEGF treatments.This increased focus on preventive care is expected to generate a sustainable pool of patients needing ongoing anti-VEGF therapies in Italy.


Italy Anti-VEGF Market Segment Insights


Anti-VEGF Market Product Insights


The Italy Anti-VEGF Market is characterized by a diverse array of products designed to combat diseases related to neovascular age-related macular degeneration, diabetic retinopathy, and other conditions affecting vision. Among the prominent products in this sector are Eylea, Lucentis, and Beovu, each playing a vital role in the treatment landscape. Eylea has gained a notable presence due to its efficacy and extended dosing intervals, making it a preferred choice for both healthcare providers and patients aiming for better compliance and outcomes.


Lucentis, which has been a cornerstone in the management of retinal diseases, emphasizes its proven track record in improving visual acuity and is frequently used in clinical practice throughout Italy, backed by extensive clinical studies. Meanwhile, Beovu has recently entered the market and has rapidly gained traction owing to its novel formulation, which offers a different mechanism of action and dosing schedule, thus expanding the therapeutic options available to healthcare practitioners. 


The market dynamics are propelled by increasing awareness of ophthalmic disorders and advancements in healthcare technology, contributing to a growing patient base requiring anti-VEGF treatments.Notably, the Italian healthcare system prioritizes innovative therapies that can lead to better patient outcomes, driving the demand for these products. Furthermore, ongoing Research and Development efforts are expected to enhance the existing range of anti-VEGF products, providing new avenues for treatment. 


The regulatory environment in Italy supports rapid access to effective therapies, also fostering market growth. However, the market faces challenges such as managing medication costs and ensuring equitable patient access across urban and rural areas.Overall, the Italian Anti-VEGF Market exhibits promising growth potential as it continues to evolve, driven by a commitment to patient-centric care and innovation in treatment methodologies.


Italy Anti VEGF Market Segment


Source: Primary Research, Secondary Research, MRFR Database, and Analyst Review


Anti-VEGF Market Disease Insights


The Italy Anti-VEGF Market, particularly within the Disease segment, is characterized by a diverse range of conditions that require effective therapeutic interventions. Among these conditions, Macular Edema and Age-Related Macular Degeneration (AMD) are significant contributors to vision loss, driving demand for anti-VEGF therapies. The Italian healthcare system prioritizes chronic diseases, with initiatives to address Diabetic Retinopathy, a condition that has seen rising prevalence due to increasing diabetes rates in the country. This segment's relevance is underscored by government health interventions aimed at early diagnosis and treatment, enhancing patient outcomes and quality of life.Retinal Vein Occlusion further enhances the complexity of the market, as it not only affects vision but also poses challenges for managing underlying health issues. The focus on research, patient education, and access to innovative therapies in Italy provides a conducive environment for growth in the Anti-VEGF Market. Overall, as healthcare policies evolve to meet the needs of an aging population, segments addressing diseases related to retinal health will likely see sustained attention and investment.


Italy Anti-VEGF Market Key Players and Competitive Insights


The Italy Anti-VEGF Market has seen significant growth due to increasing incidences of retinal diseases, particularly age-related macular degeneration (AMD) and diabetic retinopathy, necessitating the use of anti-VEGF therapies. The market is characterized by a competitive landscape where a variety of pharmaceutical companies strive to develop and market effective treatments. The presence of established players alongside emerging biopharmaceutical entities creates a dynamic environment. Regulatory support, evolving treatment protocols, and advancements in drug formulations further enhance the attractiveness of this market. As the healthcare landscape evolves, companies are focusing on strategic partnerships and innovative product launches to gain market share while addressing the unmet medical needs of patients.


Santen Pharmaceutical has established a noteworthy presence in the Italy Anti-VEGF Market, bolstered by its commitment to advancing ocular health. The company is recognized for its innovative approach to developing therapies that cater to retinal diseases, which are prevalent in the region. Santen Pharmaceutical’s strengths lie in its extensive research capabilities and a deep understanding of patients' needs, enabling it to create targeted therapeutic solutions. The firm's strong relationships with local healthcare providers and regulatory agencies enhance its market positioning, while ongoing investments in clinical trials and product development solidify its reputation as a leader in ocular therapeutics. The Italian market benefits from Santen’s dedication to both innovation and patient outcomes, allowing the company to effectively meet the demands of healthcare professionals and patients alike.


Amgen also plays a significant role in the Italy Anti-VEGF Market, known for its strong portfolio of biologics aimed at treating various ophthalmological conditions. The company has developed key products that have gained acceptance among ophthalmologists and patients, helping to strengthen its market presence. Amgen's strengths lie in its robust research and development capabilities, along with a strategic focus on enhancing patient access to its therapies. The company actively engages in collaborations and partnerships to augment its innovative pipeline, often seeking synergies with local firms to expedite the introduction of new treatments. Additionally, Amgen's experience with mergers and acquisitions has enabled it to integrate novel technologies and expand its therapeutic offerings, ensuring that it remains a formidable entity in the Italian market. By continuously refining its product line and maintaining a strong customer relationship, Amgen aims to address both the current and future needs of patients suffering from retinal diseases in Italy.


Key Companies in the Italy Anti-VEGF Market Include



  • Santen Pharmaceutical

  • Amgen

  • Teva Pharmaceutical

  • Novartis

  • Pfizer

  • Genentech

  • Roche

  • Alcon

  • Bausch Health Companies

  • Celltrion

  • Eylea

  • Regeneron

  • Horizon Therapeutics

  • Bayer

  • Bristol Myers Squibb


Italy Anti-VEGF Market Industry Developments


In recent months, the Italy Anti-VEGF Market has witnessed several key developments. Notably, in August 2023, Novartis announced a significant milestone for its anti-VEGF therapy, highlighting positive results from clinical trials aimed at treating retinal diseases, which has generated considerable interest among healthcare professionals in Italy. Additionally, Genentech continues to expand its Eylea market presence, capitalizing on the increasing prevalence of age-related macular degeneration and diabetic retinopathy in the country. Bayer has also reported a notable rise in its market valuation, driven by the growing demand for its eye care products, prompting strategic investments in Research and Development and potential expansions within the region. Among merger and acquisition activities, in June 2023, Amgen acquired Horizon Therapeutics, enhancing its portfolio in the biotechnology space that focuses on ocular indications. This acquisition has direct implications for the Italian market landscape for Anti-VEGF treatments. Over the past two to three years, the market has grown significantly due to increased awareness and access to innovative therapies, particularly those offered by Alcon and Regeneron, with Italy's healthcare infrastructure adapting to support these advancements.


Italy Anti-VEGF Market Segmentation Insights


Anti-VEGF Market Product Outlook



  • Eylea

  • Lucentis

  • Beovu


Anti-VEGF Market Disease Outlook



  • Macular Edema

  • Diabetic Retinopathy

  • Retinal Vein Occlusion

  • Age-Related Macular Degeneration

Report Attribute/Metric Source: Details
MARKET SIZE 2018 836.94(USD Million)
MARKET SIZE 2024 872.93(USD Million)
MARKET SIZE 2035 1491.59(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 4.991% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Million
KEY COMPANIES PROFILED Santen Pharmaceutical, Amgen, Teva Pharmaceutical, Novartis, Pfizer, Genentech, Roche, Alcon, Bausch Health Companies, Celltrion, Eylea, Regeneron, Horizon Therapeutics, Bayer, Bristol Myers Squibb
SEGMENTS COVERED Product, Disease
KEY MARKET OPPORTUNITIES Increasing prevalence of retinal diseases, Growing demand for personalized medicine, Advancements in drug delivery technologies, Expansion of ophthalmic clinics, Demand for cost-effective treatment options
KEY MARKET DYNAMICS Rising prevalence of ocular diseases, Growing geriatric population, Increasing adoption of biologics, Technological advancements in therapies, Competitive pricing pressures
COUNTRIES COVERED Italy


Frequently Asked Questions (FAQ) :

The Italy Anti-VEGF market is projected to be valued at 872.93 million USD in 2024.

By 2035, the overall market size is expected to reach approximately 1491.59 million USD.

The market is expected to exhibit a CAGR of 4.991 percent during the forecast period from 2025 to 2035.

Eylea is anticipated to hold a significant share with a value of 310.0 million USD in 2024, expected to rise to 532.0 million USD by 2035.

Lucentis is valued at 250.0 million USD in 2024 and projected to reach 405.0 million USD by 2035.

Beovu is forecasted to increase from 312.93 million USD in 2024 to 554.59 million USD in 2035.

Key players include Santen Pharmaceutical, Amgen, Teva Pharmaceutical, Novartis, and Roche, among others.

Emerging trends include innovations in product formulations and increased healthcare expenditure driving market growth.

The market faces challenges including regulatory hurdles and competition from alternative treatments.

Regional healthcare infrastructure advancements and demographic shifts may positively influence market expansion in Italy.

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