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Immuno Oncology Market

ID: MRFR/HC/35962-HCR
100 Pages
Rahul Gotadki
October 2025

Immuno-Oncology Market Research Report: Size, Share, Trend Analysis By Cancer Type (Lung Cancer, Melanoma, Breast Cancer, Colorectal Cancer, Leukemia, Lymphoma), By Treatment Modality (Checkpoint Inhibitors, Adoptive Cell Therapy, Cancer Vaccines, Oncolytic Viruses, Targeted Therapies), By Biomarker Type (PD-1, PD-L1, CTLA-4, LAG-3, TIM-3, IDO), By Combination Therapies (Checkpoint Inhibitor Combinations, Checkpoint Inhibitors and Targeted Therapies, Checkpoint Inhibitors and Immunotherapy, Targeted Therapy Combinations), By Disease Stage (E... read more

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Immuno Oncology Market Summary

As per Market Research Future analysis, the Immuno-Oncology Market Size was estimated at 125.69 USD Billion in 2024. The Immuno-Oncology industry is projected to grow from 137.36 USD Billion in 2025 to 333.7 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 9.2% during the forecast period 2025 - 2035

Key Market Trends & Highlights

The Immuno-Oncology Market is poised for substantial growth driven by innovative therapies and increasing cancer prevalence.

  • The emergence of combination therapies is reshaping treatment paradigms in the Immuno-Oncology Market.
  • North America remains the largest market, while the Asia-Pacific region is recognized as the fastest-growing area for immunotherapy.
  • Lung cancer continues to dominate the market, whereas melanoma is rapidly gaining traction as a key focus for new therapies.
  • Rising incidence of cancer and advancements in research and technology are significant drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 125.69 (USD Billion)
2035 Market Size 333.7 (USD Billion)
CAGR (2025 - 2035) 9.28%

Major Players

Bristol-Myers Squibb (US), Merck & Co. (US), Roche (CH), AstraZeneca (GB), Novartis (CH), Pfizer (US), Gilead Sciences (US), Eli Lilly and Company (US), Amgen (US)

Immuno Oncology Market Trends

The Immuno-Oncology Market is currently experiencing a transformative phase, characterized by rapid advancements in therapeutic approaches and a growing understanding of the immune system's role in combating cancer. This sector appears to be expanding as researchers and pharmaceutical companies explore novel immunotherapeutic agents, including monoclonal antibodies, checkpoint inhibitors, and adoptive cell transfer therapies. The increasing prevalence of various cancer types, coupled with a rising demand for personalized medicine, seems to be driving innovation and investment in this field. Furthermore, collaborations between academic institutions and industry players are likely fostering a conducive environment for groundbreaking discoveries and clinical applications. In addition, regulatory bodies are adapting to the evolving landscape of the Immuno-Oncology Market, streamlining approval processes for new therapies. This shift may enhance patient access to cutting-edge treatments, thereby potentially improving outcomes. The market's future appears promising, with ongoing research efforts aimed at overcoming existing challenges, such as treatment resistance and adverse effects. As the understanding of cancer immunology deepens, the Immuno-Oncology Market is poised for sustained growth, offering hope for patients and healthcare providers alike.

Emergence of Combination Therapies

The trend towards combination therapies in the Immuno-Oncology Market is gaining traction, as researchers investigate the synergistic effects of pairing immunotherapies with traditional treatments like chemotherapy and radiation. This approach may enhance therapeutic efficacy and broaden the patient population that can benefit from these innovative strategies.

Focus on Biomarker Development

There is a growing emphasis on the identification and validation of biomarkers within the Immuno-Oncology Market. Biomarkers could play a crucial role in predicting patient responses to specific therapies, thereby enabling more tailored treatment plans and improving overall patient outcomes.

Expansion into Rare Cancers

The Immuno-Oncology Market is increasingly targeting rare and hard-to-treat cancers, as pharmaceutical companies recognize the potential for developing specialized therapies. This focus may lead to breakthroughs in treatment options for patients with limited alternatives, thereby addressing unmet medical needs.

Immuno Oncology Market Drivers

Rising Incidence of Cancer

The increasing prevalence of cancer worldwide is a primary driver for the Immuno-Oncology Market. According to recent statistics, cancer cases are projected to rise significantly, with estimates suggesting that by 2025, there could be over 19 million new cancer cases annually. This alarming trend necessitates the development of innovative treatment options, thereby propelling the demand for immuno-oncology therapies. As healthcare systems strive to address this growing burden, investments in research and development of immuno-oncology products are likely to surge. The urgency to find effective treatments for various cancer types, including those that are traditionally hard to treat, underscores the critical role of the Immuno-Oncology Market in the broader healthcare landscape.

Advancements in Research and Technology

Technological advancements in the field of immunotherapy are significantly influencing the Immuno-Oncology Market. Innovations in genetic engineering, such as CAR-T cell therapy, have shown promising results in treating certain cancers. Furthermore, the integration of artificial intelligence in drug discovery processes is streamlining the identification of potential immuno-oncology candidates. As a result, the market is witnessing a surge in novel therapies entering clinical trials, with a notable increase in the number of FDA approvals for immuno-oncology drugs. This trend indicates a robust pipeline of therapies that could transform treatment paradigms, thereby enhancing the growth prospects of the Immuno-Oncology Market.

Increased Investment in Cancer Research

The Immuno-Oncology Market is experiencing a surge in investment from both public and private sectors. Governments and pharmaceutical companies are allocating substantial funds towards cancer research, particularly in immunotherapy. For instance, funding for cancer research initiatives has seen a marked increase, with billions of dollars being invested annually. This financial backing is crucial for advancing clinical trials and bringing innovative therapies to market. Additionally, partnerships between academic institutions and biotech firms are fostering collaborative research efforts, which are likely to yield breakthroughs in immuno-oncology treatments. Such investments not only enhance the development of new therapies but also solidify the Immuno-Oncology Market's position as a vital component of modern oncology.

Growing Awareness and Acceptance of Immunotherapy

There is a notable increase in awareness and acceptance of immunotherapy among healthcare professionals and patients, which is positively impacting the Immuno-Oncology Market. Educational initiatives and successful case studies are helping to demystify immunotherapy, leading to greater confidence in its efficacy. As more patients seek out immuno-oncology treatments, healthcare providers are increasingly incorporating these therapies into standard treatment protocols. This shift in perception is likely to drive demand for immuno-oncology products, as patients become more informed about their treatment options. The growing acceptance of immunotherapy as a viable treatment modality is expected to further bolster the Immuno-Oncology Market in the coming years.

Regulatory Support and Streamlined Approval Processes

Regulatory bodies are increasingly recognizing the potential of immuno-oncology therapies, leading to more streamlined approval processes within the Immuno-Oncology Market. Initiatives aimed at expediting the review of innovative cancer treatments are becoming more common, with agencies implementing programs that prioritize breakthrough therapies. This regulatory support is crucial for bringing new immuno-oncology products to market more quickly, thereby addressing urgent patient needs. As a result, the number of approved immuno-oncology therapies is likely to increase, fostering competition and innovation within the market. The favorable regulatory environment is expected to enhance the growth trajectory of the Immuno-Oncology Market, making it an attractive area for investment and development.

Market Segment Insights

By Cancer Type: Lung Cancer (Largest) vs. Melanoma (Fastest-Growing)

The Immuno-Oncology Market shows a significant distribution of market share across various cancer types. Lung Cancer remains the largest segment, driven by increasing incidences and advancements in immunotherapies tailored specifically to target lung tumors. Melanoma is emerging strongly as a fast-growing segment, thanks to novel therapies and heightened awareness of skin cancer treatments. Together, these segments represent a substantial portion of the market, reflecting diverse treatment strategies and patient needs.

Lung Cancer (Dominant) vs. Melanoma (Emerging)

Lung Cancer is the dominant segment in the Immuno-Oncology Market, characterized by a range of established therapies that effectively target tumor microenvironments. This segment has seen continuous innovation, with new agents approved that specifically inhibit pathways critical to lung cancer progression. On the contrary, Melanoma presents an emerging opportunity driven by rapid development in immune checkpoint inhibitors and personalized medicine approaches. Clinicians are increasingly focusing on combination therapies to elevate treatment efficacy, increasing melanoma’s market relevance and positioning it for rapid growth alongside advanced research into underlying mechanisms.

By Treatment Modality: Checkpoint Inhibitors (Largest) vs. Adoptive Cell Therapy (Fastest-Growing)

The Immuno-Oncology market reveals a multifaceted landscape with Checkpoint Inhibitors leading in market share. They dominate the segment by providing a cornerstone for cancer immunotherapy, enabling the immune system to recognize and attack cancer cells more effectively. Other modalities, like Adoptive Cell Therapy, Cancer Vaccines, Oncolytic Viruses, and Targeted Therapies, also contribute to the market but at varying levels of acceptance and adoption, illustrating a diverse portfolio of treatment options available to oncologists. Furthermore, growth trends indicate that while Checkpoint Inhibitors remain prevalent, Adoptive Cell Therapy is gaining traction rapidly, attributed to advanced manufacturing processes and clinical success stories. Emerging modalities such as Cancer Vaccines show potential, spurring research activities, while Oncolytic Viruses are noted for their innovative and unique mechanisms of action. The overall market is driven by the increasing prevalence of cancer, advances in biomedical research, and the need for personalized therapies.

Checkpoint Inhibitors (Dominant) vs. Cancer Vaccines (Emerging)

Checkpoint Inhibitors represent the dominant modality within the Immuno-Oncology market, known for their ability to unleash the immune system's capability to destroy tumors. In contrast, Cancer Vaccines, while classified as emerging, are gaining attention for their potential to provide long-lasting protection against cancer recurrence. Checkpoint Inhibitors, such as PD-1 and CTLA-4 inhibitors, have shown substantial efficacy in a range of cancers, creating a significant demand among oncologists. Conversely, Cancer Vaccines are undergoing revitalization through innovative approaches, including personalized and therapeutic vaccines that target specific tumor antigens. As research progresses, the potential for combination therapies involving these modalities may enhance treatment efficacy, paving the way for broader acceptance and integration into standard oncology practices.

By Biomarker Type: PD-1 (Largest) vs. CTLA-4 (Fastest-Growing)

In the Immuno-Oncology Market, the biomarker type segment shows significant diversity in market share. PD-1 leads this segment as the largest biomarker, reflecting its robust application in numerous cancer therapies. Meanwhile, PD-L1 and CTLA-4 follow closely, offering substantial shares as key players in immunotherapy, while emerging biomarkers like LAG-3, TIM-3, and IDO are gradually gaining ground. Despite being smaller, these emerging markers indicate a shift toward a more personalized approach to oncology treatments, highlighting their growing significance in patient selection and therapeutic strategies. The growth trends within the biomarker type segment are indicative of an evolving landscape in Immuno-Oncology. PD-1 remains dominant due to its established role in checkpoint inhibition, bolstered by extensive research and clinical success. On the other hand, CTLA-4 is recognized as the fastest-growing biomarker, driven by increased approvals and combination therapies that enhance efficacy. This growth is supported by a heightened focus on precision medicine and the integration of novel biomarkers into clinical decision-making, which promises to transform treatment paradigms and improve patient outcomes.

PD-1 (Dominant) vs. LAG-3 (Emerging)

PD-1, as the dominant biomarker in the Immuno-Oncology Market, has become a cornerstone of cancer immunotherapy, proving its efficacy in various malignancies such as melanoma and lung cancer. Its success is reflected in numerous drug approvals and a solid pipeline of candidates. CD274, the ligand for PD-1, further illustrates the interplay of PD-L1 in combination therapies. Conversely, LAG-3, while still emerging, is gaining attention due to its unique mechanism that complements existing therapies. As research progresses, LAG-3 is showing potential in enhancing the efficacy of treatments, especially in combination with PD-1 inhibitors. This positioning marks it as a promising target for future therapies, signifying a shift in the landscape towards more nuanced and effective combinations that cater to individual patient needs.

By Combination Therapies: Checkpoint Inhibitor Combinations (Largest) vs. Targeted Therapy Combinations (Fastest-Growing)

The Combination Therapies segment in the Immuno-Oncology Market is widely recognized for its diverse set of treatment options. Among these, Checkpoint Inhibitor Combinations hold the largest market share due to their proven efficacy and widespread adoption in various cancer types. Targeted Therapy Combinations are gaining significant traction as an emerging force, fueled by advancements in personalized medicine and precision therapeutics that complement traditional immunotherapy approaches.

Checkpoint Inhibitor Combinations (Dominant) vs. Targeted Therapy Combinations (Emerging)

Checkpoint Inhibitor Combinations are at the forefront of the Immuno-Oncology market, leveraging synergistic effects to enhance patient outcomes. These therapies, which include combinations of PD-1, PD-L1, and CTLA-4 inhibitors, have demonstrated significant clinical benefits, contributing to their dominant market position. Meanwhile, Targeted Therapy Combinations are emerging as key players, harnessing specific genetic mutations and molecular targets to improve the effectiveness and tolerability of treatments. As research progresses, both segments are expected to evolve, with Checkpoint Inhibitor Combinations remaining robust, while Targeted Therapy Combinations capture a growing share through innovative clinical trials and combination strategies.

By Disease Stage: Advanced Stage (Largest) vs. Metastatic Disease (Fastest-Growing)

In the Immuno-Oncology market, the distribution among disease stages reveals that the Advanced Stage currently holds the largest market share, benefiting from robust treatment protocols and increasing clinical approvals. This stage encompasses various cancers that have progressed significantly, requiring more advanced therapeutic interventions, thereby dominating the overall segment. Meanwhile, the Metastatic Disease segment, which involves cancer that has spread beyond its original site, is rapidly gaining traction among healthcare providers and researchers as new therapies targeting this challenging stage are emerging.

Advanced Stage (Dominant) vs. Metastatic Disease (Emerging)

The Advanced Stage in the Immuno-Oncology market is characterized by its well-established therapies and a growing patient population seeking innovative treatments. This phase often incorporates combination therapies and immune checkpoint inhibitors tailored to combat resilient tumors. In contrast, the Metastatic Disease segment is emerging as a critical area of focus due to rising incidences of cancer metastasis, which poses significant challenges for treatment. Researchers are increasingly prioritizing the development of novel therapeutics aimed at addressing metastatic pathways, making this segment one of the fastest-growing areas within the market.

Get more detailed insights about Immuno Oncology Market

Regional Insights

North America dominated this space, holding a majority with a valuation of 58.0 USD Billion in 2023 and projected to reach 129.0 USD Billion by 2032, driven by advanced healthcare infrastructure and significant investments in research.

Europe followed as a significant player with a market value of 30.0 USD Billion in 2023, increasing to 70.0 USD Billion by 2032, indicative of robust regulatory frameworks supporting innovative therapies.

South America, while smaller in comparison with a valuation of 5.0 USD Billion, is expected to grow to 12.0 USD Billion, driven by increasing healthcare access and awareness. The Asia Pacific region was also on a growth trajectory, moving from 8.0 USD Billion to 15.0 USD Billion as the demand for advanced treatment options rose.

Meanwhile, the Middle East and Africa represented a niche market, valued at 4.25 USD Billion in 2023 and forecast to reach 7.8 USD Billion, presenting opportunities due to expanding healthcare initiatives. The data showed diverse regional dynamics within the Immuno-Oncology Market, with North America significantly leading the industry.

Immuno Oncology Market Regional Image

Key Players and Competitive Insights

Innovative products and technology development remain the vital approach of the major players in the Immuno-oncology Market. In an attempt to gain a significant market position, the leading players in the Immuno-oncology Market are developing their market presence by concentrating on considerable partnerships with major market experiments, acquisitions, and mergers and expanding popular products.

Also, numerous promising candidates in the various stages of the clinical trials process can be witnessed in the Immuno-oncology Market development pipeline. Undeniably, it will significantly enhance the growth perspectives of the Immuno-oncology Market.

The prominent competitor in the Immuno-oncology Market can be observed to be the diversified group in the field, namely, Bristol-Myers Squibb. It can be seen that the company's portfolio of marketed drugs is undoubtedly strong. In the Immuno-oncology Market, the therapy that can be approved by the company is Opdivo.

Being a PD-1 inhibitor, it is mostly used to treat several types of cancer, including non-small-cell lung, squamous cell lung, melanoma, and renal cell. Yervoy, as a CTLA-4 inhibitor, is applicable for the melanoma treatment by the company.

Also, the activity of research and development of the company can be considered to be appealing. The numerous promising candidates of the Immuno-oncology Market in the company's portfolio in the various stages of the clinical trials process can be noticed.

Another major competitor in the Immuno-oncology Market is Merck Co. The company comprises the Immuno-oncology Market product Keytruda as a PD-1 inhibitor, which can be mostly used to treat non-small-cell lung and melanoma and also urinary bladder cancers.

Moreover, an attractive pipeline with several promising candidates can be found in the company in the various stages of the clinical trial process. The approach of Merck Co. to develop combination therapy based on the numerous Immuno-oncology Market mechanisms utilized to enhance the patient's condition can be noticed.

Key Companies in the Immuno Oncology Market market include

Industry Developments

  • Q2 2024: Merck’s Keytruda wins FDA approval for new lung cancer use The U.S. FDA approved Merck’s immunotherapy Keytruda for use in combination with chemotherapy as a first-line treatment for certain patients with advanced or metastatic non-small cell lung cancer.
  • Q2 2024: Bristol Myers, BioNTech Announce Strategic Immuno-Oncology Partnership Bristol Myers Squibb and BioNTech entered a multi-year partnership to co-develop and commercialize novel immuno-oncology therapies, focusing on next-generation checkpoint inhibitors and personalized cancer vaccines.
  • Q2 2024: Gilead Sciences Completes Acquisition of CymaBay Therapeutics Gilead Sciences announced the completion of its acquisition of CymaBay Therapeutics, expanding its immuno-oncology pipeline with CymaBay’s investigational cancer immunotherapies.
  • Q2 2024: Immatics Announces $110 Million Private Placement Financing Immatics N.V. raised $110 million in a private placement to advance its pipeline of TCR-based immuno-oncology therapies targeting solid tumors.
  • Q2 2024: AstraZeneca opens new $300M manufacturing facility for cancer immunotherapies AstraZeneca inaugurated a new $300 million manufacturing facility dedicated to the production of immuno-oncology drugs, aiming to scale up supply for global markets.
  • Q3 2024: Moderna and Merck expand cancer vaccine collaboration with $250m investment Moderna and Merck announced an expansion of their collaboration to develop and commercialize personalized cancer vaccines, with Merck investing an additional $250 million.
  • Q3 2024: Nektar Therapeutics Appoints New Chief Executive Officer Nektar Therapeutics announced the appointment of a new CEO to lead the company’s strategic focus on immuno-oncology drug development.
  • Q3 2024: FDA approves Roche’s Tecentriq for early-stage lung cancer The U.S. FDA approved Roche’s immunotherapy Tecentriq as an adjuvant treatment for certain patients with early-stage non-small cell lung cancer following surgery and chemotherapy.
  • Q3 2024: Novartis to acquire Chinook Therapeutics in $3.2 billion immuno-oncology deal Novartis announced an agreement to acquire Chinook Therapeutics for $3.2 billion, strengthening its immuno-oncology portfolio with Chinook’s pipeline assets.
  • Q4 2024: Adaptimmune and Genentech Announce Strategic Collaboration to Develop Allogeneic Cell Therapies Adaptimmune and Genentech entered a strategic collaboration to co-develop and commercialize allogeneic cell therapies for cancer, leveraging Adaptimmune’s TCR technology.
  • Q4 2024: Immunocore Announces FDA Approval of KIMMTRAK for Uveal Melanoma Immunocore received FDA approval for KIMMTRAK, the first TCR-based immunotherapy for the treatment of unresectable or metastatic uveal melanoma.
  • Q1 2025: Pfizer launches new immuno-oncology research center in Boston Pfizer opened a new research center in Boston focused on the discovery and development of next-generation immuno-oncology therapies.

Future Outlook

Immuno Oncology Market Future Outlook

The Immuno-Oncology Market is projected to grow at a 9.28% CAGR from 2024 to 2035, driven by advancements in therapies, increasing cancer prevalence, and enhanced R&D investments.

New opportunities lie in:

  • Development of personalized immunotherapies targeting specific cancer mutations.
  • Expansion of combination therapies integrating immuno-oncology with traditional treatments.
  • Investment in digital health technologies for patient monitoring and engagement.

By 2035, the Immuno-Oncology Market is expected to be robust, driven by innovation and strategic partnerships.

Market Segmentation

Immuno Oncology Market Cancer Type Outlook

  • Lung Cancer
  • Melanoma
  • Breast Cancer
  • Colorectal Cancer
  • Leukemia
  • Lymphoma

Immuno Oncology Market Disease Stage Outlook

  • Early Stage
  • Advanced Stage
  • Metastatic Disease

Immuno Oncology Market Biomarker Type Outlook

  • PD-1
  • PD-L1
  • CTLA-4
  • LAG-3
  • TIM-3
  • IDO

Immuno Oncology Market Treatment Modality Outlook

  • Checkpoint Inhibitors
  • Adoptive Cell Therapy
  • Cancer Vaccines
  • Oncolytic Viruses
  • Targeted Therapies

Immuno Oncology Market Combination Therapies Outlook

  • Checkpoint Inhibitor Combinations
  • Checkpoint Inhibitors and Targeted Therapies
  • Checkpoint Inhibitors and Immunotherapy
  • Targeted Therapy Combinations

Report Scope

MARKET SIZE 2024 125.69(USD Billion)
MARKET SIZE 2025 137.36(USD Billion)
MARKET SIZE 2035 333.7(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR) 9.28% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Billion
Key Companies Profiled Bristol-Myers Squibb (US), Merck & Co. (US), Roche (CH), AstraZeneca (GB), Novartis (CH), Pfizer (US), Gilead Sciences (US), Eli Lilly and Company (US), Amgen (US)
Segments Covered Cancer Type, Treatment Modality, Biomarker Type, Combination Therapies, Disease Stage, Regional
Key Market Opportunities Advancements in personalized therapies and combination treatments drive growth in the Immuno-Oncology Market.
Key Market Dynamics Rising demand for personalized therapies drives innovation and competition in the Immuno-Oncology Market.
Countries Covered North America, Europe, APAC, South America, MEA

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FAQs

What is the current valuation of the Immuno-Oncology Market as of 2024?

The Immuno-Oncology Market was valued at 125.69 USD Billion in 2024.

What is the projected market size for the Immuno-Oncology Market by 2035?

The market is projected to reach 333.7 USD Billion by 2035.

What is the expected CAGR for the Immuno-Oncology Market during the forecast period 2025 - 2035?

The expected CAGR for the Immuno-Oncology Market during 2025 - 2035 is 9.28%.

Which cancer types are leading in market valuation within the Immuno-Oncology sector?

Lung Cancer and Breast Cancer are leading, with valuations of 30.0 to 80.0 USD Billion and 25.0 to 70.0 USD Billion, respectively.

What are the key treatment modalities driving the Immuno-Oncology Market?

Checkpoint Inhibitors dominate the market, with a valuation range of 45.0 to 120.0 USD Billion.

How do combination therapies impact the Immuno-Oncology Market?

Combination therapies, particularly Targeted Therapy Combinations, are projected to reach 50.69 to 138.7 USD Billion.

Which biomarkers are most significant in the Immuno-Oncology Market?

PD-L1 and PD-1 are significant biomarkers, with valuations ranging from 30.0 to 80.0 USD Billion and 25.0 to 70.0 USD Billion, respectively.

What role do key players like Bristol-Myers Squibb and Merck & Co. play in the market?

Key players such as Bristol-Myers Squibb and Merck & Co. are instrumental in driving innovation and market growth.

What is the market outlook for advanced stage cancer treatments in Immuno-Oncology?

Advanced stage cancer treatments are expected to grow significantly, with a projected valuation of 50.0 to 130.0 USD Billion.

How does the Immuno-Oncology Market compare across different disease stages?

The market shows a strong focus on advanced and metastatic disease stages, with valuations of 50.0 to 130.0 USD Billion and 50.69 to 133.7 USD Billion, respectively.

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