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    Immuno Oncology Market

    ID: MRFR/HC/35962-HCR
    100 Pages
    Rahul Gotadki
    October 2025

    Immuno-Oncology Market Research Report By Cancer Type (Lung Cancer, Melanoma, Breast Cancer, Colorectal Cancer, Leukemia, Lymphoma), By Treatment Modality (Checkpoint Inhibitors, Adoptive Cell Therapy, Cancer Vaccines, Oncolytic Viruses, Targeted Therapies), By Biomarker Type (PD-1, PD-L1, CTLA-4, LAG-3, TIM-3, IDO), By Combination Therapies (Checkpoint Inhibitor Combinations, Checkpoint Inhibitors and Targeted Therapies, Checkpoint Inhibitors and Immunotherapy, Targeted Therapy Combinations), By Disease Stage (Early Stage, Advanced Stage, M...

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    Immuno Oncology Market Infographic
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    Immuno Oncology Market Summary

    The Global Immuno-Oncology Market is projected to grow from 125.69 USD Billion in 2024 to 333.70 USD Billion by 2035, reflecting a robust expansion trajectory.

    Key Market Trends & Highlights

    Immuno-Oncology Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 9.28 percent from 2025 to 2034.
    • By 2035, the market valuation is anticipated to reach 333.7 USD Billion, indicating substantial growth potential.
    • in 2024, the market is valued at 125.69 USD Billion, showcasing a strong foundation for future expansion.
    • Growing adoption of immunotherapy due to increasing cancer prevalence is a major market driver.

    Market Size & Forecast

    2024 Market Size 125.69 (USD Billion)
    2035 Market Size 333.70 (USD Billion)
    CAGR (2025-2035) 9.28%

    Major Players

    Bristol-Myers Squibb, Merck Co., Gilead Sciences, Roche, Seagen, Amgen, EMD Serono, AstraZeneca, AbbVie, Pfizer, Celgene, Ipsen, Novartis, BeiGene

    Immuno Oncology Market Trends

    The Immuno-Oncology Market is driven by several key factors: rising cancer incidence, increasing adoption of immunotherapies, technological advancements, growing awareness about immuno-oncology, and government initiatives.

    The rising prevalence of cancer and the growing demand for effective cancer therapies are major drivers of the market. Over the past few years, immunotherapies have gained significant traction due to their ability to enhance the body's immune response against cancer cells.

    In recent years, the market has witnessed advancements in targeted therapies, such as the development of CAR T-cell therapies and bispecific antibodies, which offer personalized treatments with improved efficacy.

    Moreover, increasing research and development efforts are leading to a growing pipeline of novel immuno-oncology agents, creating opportunities for market growth.

    Another significant trend is the growing emphasis on combination therapies, where immuno-oncology drugs are combined with other modalities, such as chemotherapy or radiation therapy, to enhance treatment outcomes. This approach has demonstrated promising results in clinical trials and is expected to drive market growth.

    .webp

    The ongoing advancements in immuno-oncology therapies suggest a transformative shift in cancer treatment paradigms, potentially enhancing patient outcomes and survival rates.

    National Cancer Institute

    Immuno Oncology Market Drivers

    Rising Prevalence of Cancer

    The increasing incidence of cancer globally serves as a primary driver for the Global Immuno-Oncology Market Industry. With cancer cases projected to rise significantly, the demand for innovative treatment options is paramount. In 2024, the market is valued at 125.7 USD Billion, reflecting the urgent need for effective therapies. Immuno-oncology, which harnesses the body’s immune system to combat cancer, is gaining traction as a viable alternative to traditional treatments. This trend is expected to continue, with the market anticipated to reach 333.7 USD Billion by 2035, indicating a robust growth trajectory fueled by the rising cancer burden.

    Market Segment Insights

    Immuno-Oncology Market Cancer Type Insights

    The Immuno-Oncology Market, particularly concerning the Cancer Type segment, played a vital role in the overall growth of the industry.

    Lung Cancer led this segment with a remarkable valuation of 40.0 USD Billion in 2023 and is projected to nearly double to 90.0 USD Billion by 2032, largely due to the high prevalence rates and the increasing emphasis on targeted and personalized therapies.

    Following closely, Melanoma stood at a market valuation of 30.0 USD Billion in 2023, anticipated to rise to 65.0 USD Billion, which highlighted its growing importance as innovative treatments emerge, addressing the underlying genetics of this aggressive skin cancer.

    Breast Cancer, with a value of 20.0 USD Billion in 2023, was also on a strong upward trajectory towards 50.0 USD Billion by 2032. This increase reflected the significant focus on immunotherapy in addressing various subtypes of breast cancer as therapies continue to evolve and gain regulatory approvals.

    Colorectal Cancer, regarded as a common yet often under-focused area, held a market valuation of 10.0 USD Billion in 2023, with an expected rise to 20.0 USD Billion, indicating steady growth amidst increasing awareness and advancements in diagnostics and treatment strategies.

    Immuno-Oncology Market Treatment Modality Insights

    The segment encompasses various approaches, including Checkpoint Inhibitors, which have gained traction due to their ability to enhance the immune response against tumors, making them a cornerstone of immuno-oncology.

    Adoptive Cell Therapy is also pivotal as it utilizes the patient's immune cells, demonstrating high efficacy in certain cancer types. Cancer Vaccines represent another crucial area, providing a proactive avenue for cancer prevention and management by stimulating the body's immune response to fight against malignancies.

    Oncolytic Viruses harness the ability to selectively infect and destroy cancer cells, presenting innovative therapeutic potential. Additionally, Targeted Therapies have become significant as they offer personalized treatment options based on specific genetic markers.

    The evolving landscape of the Immuno-Oncology Market segmentation reveals robust trends, with continuous advancements in research and development seen as key growth drivers. However, challenges such as high treatment costs and regulatory hurdles remain evident, creating both obstacles and opportunities within this dynamically growing field.

    Immuno-Oncology Market Biomarker Type Insights

    The segment plays a crucial role in the development of targeted therapies, with various biomarkers like PD-1 and PD-L1 leading the market due to their significant role in cancer treatment.

    These biomarkers facilitate the identification of patients who are more likely to respond to immune checkpoint inhibitors, ensuring more effective treatment protocols. CTLA-4, meanwhile, is integral in modulating the immune response against tumors, further driving market demand.

    Other important biomarkers such as LAG-3, TIM-3, and IDO are emerging, offering promising prospects for enhancing treatment strategies and patient outcomes.

    As the Immuno-Oncology Market data suggests, advancements in biomarker discovery and personalization of therapy are key trends fueling market growth, all while grappling with challenges like regulatory hurdles and the need for extensive clinical testing.

    The increasing emphasis on precision medicine creates opportunities for innovation in the biomarker-type segment, aligning with the overall market strategy toward more effective and tailored oncology therapies.

    Immuno-Oncology Market Combination Therapies Insights

    The Combination Therapies segment of the Immuno-Oncology Market is a robust area with considerable importance. This segment encapsulates various strategies that enhance treatment efficacy beyond monotherapy.

    Checkpoint Inhibitor Combinations leverage the synergistic effects of multiple agents, leading to improved patient outcomes and higher response rates. Moreover, the pairing of Checkpoint Inhibitors and Targeted Therapies takes advantage of different mechanisms to combat cancer, making it a significant trend in cancer treatment.

    Checkpoint Inhibitors and Immunotherapy form another crucial approach, as they activate the immune system while directly targeting tumor cells. Additionally, Targeted Therapy Combinations play a vital role by utilizing specific characteristics of cancer cells for effective treatment.

    This diverse landscape within the Combination Therapies segment reflects a growing trend driven by the need for enhanced therapeutic options. Market growth is propelled by increasing research activities, the rising prevalence of cancers, and the shift towards personalized medicine.

    Immuno-Oncology Market data reveals that these combination strategies are expected to address existing challenges in cancer treatment, offering numerous opportunities for pharmaceutical advancements and patient care.

    Immuno-Oncology Market Disease Stage Insights

    The Immuno-Oncology Market has been experiencing robust growth, with a notable focus on the Disease Stage segment, which plays a crucial role in treatment outcomes.

    The segmentation within the Disease Stage includes Early Stage, Advanced Stage, and Metastatic Disease, with each contributing significantly to the overall market dynamics. The Early Stage category is critical as it offers a higher potential for successful treatment and recovery, driving demand for immunotherapy options.

    The Advanced Stage segment sees considerable investment due to the need for new therapies that can provide better outcomes for patients facing more aggressive diseases. Additionally, Metastatic Disease represents a significant portion of the market as it requires advanced treatment options, often yielding higher healthcare expenditure.

    The Immuno-Oncology Market data demonstrates that as the understanding of cancer biology evolves, tailored therapies across these stages provide substantial growth opportunities while also posing challenges related to regulatory approvals and market access.

    The interplay between these stages continues to shape market trends and drive the Immuno-Oncology Market statistics forward.

    Get more detailed insights about Immuno Oncology Market

    Regional Insights

    North America dominated this space, holding a majority with a valuation of 58.0 USD Billion in 2023 and projected to reach 129.0 USD Billion by 2032, driven by advanced healthcare infrastructure and significant investments in research.

    Europe followed as a significant player with a market value of 30.0 USD Billion in 2023, increasing to 70.0 USD Billion by 2032, indicative of robust regulatory frameworks supporting innovative therapies.

    South America, while smaller in comparison with a valuation of 5.0 USD Billion, is expected to grow to 12.0 USD Billion, driven by increasing healthcare access and awareness. The Asia Pacific region was also on a growth trajectory, moving from 8.0 USD Billion to 15.0 USD Billion as the demand for advanced treatment options rose.

    Meanwhile, the Middle East and Africa represented a niche market, valued at 4.25 USD Billion in 2023 and forecast to reach 7.8 USD Billion, presenting opportunities due to expanding healthcare initiatives. The data showed diverse regional dynamics within the Immuno-Oncology Market, with North America significantly leading the industry.

    Immuno-Oncology Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    Innovative products and technology development remain the vital approach of the major players in the Immuno-oncology Market. In an attempt to gain a significant market position, the leading players in the Immuno-oncology Market are developing their market presence by concentrating on considerable partnerships with major market experiments, acquisitions, and mergers and expanding popular products.

    Also, numerous promising candidates in the various stages of the clinical trials process can be witnessed in the Immuno-oncology Market development pipeline. Undeniably, it will significantly enhance the growth perspectives of the Immuno-oncology Market.

    The prominent competitor in the Immuno-oncology Market can be observed to be the diversified group in the field, namely, Bristol-Myers Squibb. It can be seen that the company's portfolio of marketed drugs is undoubtedly strong. In the Immuno-oncology Market, the therapy that can be approved by the company is Opdivo.

    Being a PD-1 inhibitor, it is mostly used to treat several types of cancer, including non-small-cell lung, squamous cell lung, melanoma, and renal cell. Yervoy, as a CTLA-4 inhibitor, is applicable for the melanoma treatment by the company.

    Also, the activity of research and development of the company can be considered to be appealing. The numerous promising candidates of the Immuno-oncology Market in the company's portfolio in the various stages of the clinical trials process can be noticed.

    Another major competitor in the Immuno-oncology Market is Merck Co. The company comprises the Immuno-oncology Market product Keytruda as a PD-1 inhibitor, which can be mostly used to treat non-small-cell lung and melanoma and also urinary bladder cancers.

    Moreover, an attractive pipeline with several promising candidates can be found in the company in the various stages of the clinical trial process. The approach of Merck Co. to develop combination therapy based on the numerous Immuno-oncology Market mechanisms utilized to enhance the patient's condition can be noticed.

    Key Companies in the Immuno Oncology Market market include

    Industry Developments

    • Q2 2024: Merck’s Keytruda wins FDA approval for new lung cancer use The U.S. FDA approved Merck’s immunotherapy Keytruda for use in combination with chemotherapy as a first-line treatment for certain patients with advanced or metastatic non-small cell lung cancer.
    • Q2 2024: Bristol Myers, BioNTech Announce Strategic Immuno-Oncology Partnership Bristol Myers Squibb and BioNTech entered a multi-year partnership to co-develop and commercialize novel immuno-oncology therapies, focusing on next-generation checkpoint inhibitors and personalized cancer vaccines.
    • Q2 2024: Gilead Sciences Completes Acquisition of CymaBay Therapeutics Gilead Sciences announced the completion of its acquisition of CymaBay Therapeutics, expanding its immuno-oncology pipeline with CymaBay’s investigational cancer immunotherapies.
    • Q2 2024: Immatics Announces $110 Million Private Placement Financing Immatics N.V. raised $110 million in a private placement to advance its pipeline of TCR-based immuno-oncology therapies targeting solid tumors.
    • Q2 2024: AstraZeneca opens new $300M manufacturing facility for cancer immunotherapies AstraZeneca inaugurated a new $300 million manufacturing facility dedicated to the production of immuno-oncology drugs, aiming to scale up supply for global markets.
    • Q3 2024: Moderna and Merck expand cancer vaccine collaboration with $250m investment Moderna and Merck announced an expansion of their collaboration to develop and commercialize personalized cancer vaccines, with Merck investing an additional $250 million.
    • Q3 2024: Nektar Therapeutics Appoints New Chief Executive Officer Nektar Therapeutics announced the appointment of a new CEO to lead the company’s strategic focus on immuno-oncology drug development.
    • Q3 2024: FDA approves Roche’s Tecentriq for early-stage lung cancer The U.S. FDA approved Roche’s immunotherapy Tecentriq as an adjuvant treatment for certain patients with early-stage non-small cell lung cancer following surgery and chemotherapy.
    • Q3 2024: Novartis to acquire Chinook Therapeutics in $3.2 billion immuno-oncology deal Novartis announced an agreement to acquire Chinook Therapeutics for $3.2 billion, strengthening its immuno-oncology portfolio with Chinook’s pipeline assets.
    • Q4 2024: Adaptimmune and Genentech Announce Strategic Collaboration to Develop Allogeneic Cell Therapies Adaptimmune and Genentech entered a strategic collaboration to co-develop and commercialize allogeneic cell therapies for cancer, leveraging Adaptimmune’s TCR technology.
    • Q4 2024: Immunocore Announces FDA Approval of KIMMTRAK for Uveal Melanoma Immunocore received FDA approval for KIMMTRAK, the first TCR-based immunotherapy for the treatment of unresectable or metastatic uveal melanoma.
    • Q1 2025: Pfizer launches new immuno-oncology research center in Boston Pfizer opened a new research center in Boston focused on the discovery and development of next-generation immuno-oncology therapies.
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    Future Outlook

    Immuno Oncology Market Future Outlook

    The Global Immuno-Oncology Market is projected to grow at a 9.28% CAGR from 2024 to 2034, driven by advancements in personalized therapies, increasing cancer prevalence, and enhanced R&D investments.

    New opportunities lie in:

    • Develop combination therapies to enhance efficacy and reduce resistance in treatment regimens.
    • Invest in biomarker discovery to personalize immuno-oncology treatments for better patient outcomes.
    • Expand access to immuno-oncology therapies in emerging markets through strategic partnerships.

    By 2035, the Immuno-Oncology Market is expected to achieve substantial growth, solidifying its critical role in cancer treatment.

    Market Segmentation

    Immuno-Oncology Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Immuno-Oncology Market Cancer Type Outlook

    • Lung Cancer
    • Melanoma
    • Breast Cancer
    • Colorectal Cancer
    • Leukemia
    • Lymphoma

    Immuno-Oncology Market Disease Stage Outlook

    • Early Stage
    • Advanced Stage
    • Metastatic Disease

    Immuno-Oncology Market Biomarker Type Outlook

    • PD-1
    • PD-L1
    • CTLA-4
    • LAG-3
    • TIM-3
    • IDO

    Immuno-Oncology Market Treatment Modality Outlook

    • Checkpoint Inhibitors
    • Adoptive Cell Therapy
    • Cancer Vaccines
    • Oncolytic Viruses
    • Targeted Therapies

    Immuno-Oncology Market Combination Therapies Outlook

    • Checkpoint Inhibitor Combinations
    • Checkpoint Inhibitors and Targeted Therapies
    • Checkpoint Inhibitors and Immunotherapy
    • Targeted Therapy Combinations

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024  125.69 (USD Billion)
    Market Size 2025  137.36 (USD Billion)
    Market Size 2035 333.70 (USD Billion)
    Compound Annual Growth Rate (CAGR) 9.28% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Incyte Bristol Myers Squibb, Gilead Sciences, Roche, Seagen, Merck Co., Amgen, EMD Serono, AstraZeneca, AbbVie, Pfizer, Celgene, Ipsen, Novartis, BeiGene
    Segments Covered Cancer Type, Treatment Modality, Biomarker Type, Combination Therapies, Disease Stage, Regional
    Key Market Opportunities 1 Growing cancer burden 2 Advancements in precision medicine 3 Rise in immunotherapy research and development 4 Government funding and initiatives 5 Increasing awareness of immune-oncology therapies
    Key Market Dynamics Growing Prevalence of Cancer  Technological Advancements  Increasing Healthcare Spending  Government Support for Research  Strategic Collaborations and Acquisitions
    Countries Covered North America, Europe, APAC, South America, MEA

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    FAQs

    What is the projected growth of the Immuno-Oncology market?

    The Immuno-Oncology market is the expected increase in total market value of 333.7 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Immuno-Oncology market?

    Immuno-Oncology market size was valued at approximately 125.69 billion USD in 2024. This figure will reach 333.7 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Immuno-Oncology market?

    Immuno-Oncology market is expected to grow at a CAGR of 9.28% between 2025 and 2035.

    How much will the Immuno-Oncology market be worth by 2035?

    Immuno-Oncology market is expected to be worth of 333.7 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Immuno-Oncology market perform over the next 10 years?

    Over the next 10 years the Immuno-Oncology market is expected to shift from usd billion 125.69 to 333.7 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region is projected to have the largest market share in the Immuno-Oncology Market by 2035?

    North America is projected to have the largest market share, valued at 129.0 USD Billion by 2035.

    How much is the Immuno-Oncology Market for lung cancer expected to be worth by 2035?

    The market for lung cancer in the Immuno-Oncology Market is expected to reach 90.0 USD Billion by 2035.

    What are the major players in the Immuno-Oncology Market?

    Key players in the market include Incyte, Bristol Myers Squibb, Gilead Sciences, and Roche, among others.

    What is the projected market size for melanoma in the Immuno-Oncology Market by 2035?

    The market for melanoma is projected to be valued at 65.0 USD Billion by 2035.

    How much is the Immuno-Oncology Market for breast cancer expected to grow by 2035?

    The market for breast cancer is expected to grow to 50.0 USD Billion by 2035.

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