Bone Graft Substitute Market Outlook on Growing Bone & Joint Disorder Incidences to Drive the Need for Bone Graft Substitutes

Published On: December 2022

Bone grafts and substitutes are used to replace missing bones or heal fractured bones. They are made up of osteoconductive matrix, which fills up wounds and aids in healing. Osteoinductive proteins encourage the division of identical bone cells into two, and osteogenic cells create bone when the conditions are right. They don't trigger an antigen-antibody reaction and are bioresorbable by nature. Due to these qualities, they are frequently utilized in spinal, face, foot, ankle, and trauma procedures, as well as for healing fractures and bone injuries.

The introduction of new polymer and ceramic materials with physiologically superior properties is one of the significant market developments currently being seen. The emergence of new manufacturing technologies like fast prototyping and 3D printing aids the creation of free-form biomaterial scaffolds for tissue regeneration. Additionally, there is a growing demand for bone replacement grafts and substitutes because of increased morbidity rates, an aging population, and an increase in osteoarthritis cases, according to the bone graft substitute market outlook.

Along with this, a shift toward minimally invasive procedures and patients' more informed understanding of the advantages of bone regeneration using biologics are fueling the expansion of the bone graft substitute market. The availability of cutting-edge products in various sizes and forms, the rising incidence of orthopedic issues and periodontal illnesses, and the expanding number of studies looking into how to improve the bioactivity of bone graft substitutes are a few more growth-inducing aspects per the bone graft substitute market analysis.

Growth Story

It is predicted that the industry will benefit significantly from rising graft utilization for dental treatments through the projected period. The grafts are typically utilized as a scaffold and filler to aid in developing new bone and accelerate recovery. The bone graft substitute market is expected to rise as dental implant surgical procedures and cutting-edge methods like bone regeneration and bone grafts become more widely accepted. Additionally, as dental implants become more successful, there is a rising demand for dental bone graft substitutes.

As the number of knees and hip replacement surgeries rises, the joint reconstruction market is anticipated to expand steadily over the forecast period. The Center for Orthopedic and Neurological Care and Research projects that by 2030, there will be 3.5 million total knee replacement surgeries performed annually, an increase of 673%. In the years to come, the long bone section is projected to experience significant expansion. One of the causes promoting the use of bone replacement grafts and substitutes is lengthy bone procedures in injuries and trauma to the extremities brought on by auto accidents and sports injuries. Baxter, Stryker, and Medtronic are significant players in the bone graft substitute market.

The main obstacles impeding the expansion of the bone graft and substitution market are the ethical concerns related to bone grafting treatments and the high surgery cost. Despite all the significant aspects, a person's moral convictions impede the market's expansion. As a result, the market growth for bone grafts and substitute products is constrained by the ethical concerns surrounding bone grafting techniques. The cost for a single implant in the straightforward technique of bone grafting utilizing cadaveric bone ranges from USD 200 to USD 1200. Therefore, it is anticipated that the high cost of surgeries may impede the expansion of the bone graft substitute market.

Moreover, the growing elderly population more susceptible to orthopedic conditions is driving up demand for corrective surgery, which is expected to accelerate the bone graft substitute market trends in the near term. The World Health Organization predicts that the elderly population will double, from 12% to 22%, between 2015 and 2050.

Therefore, the following are significant drivers of the global bone graft and substitute market growth:

• Increase in joint repair and spinal fusion


• Degenerative joint illnesses are on the rise because of unhealthy lifestyle choices


• Aging population growth


• More procedures and treatments for musculoskeletal conditions


• Fast-moving biocompatible synthetic bone graft development


• Demand for orthopedic surgery is rising


• Technological advancement

COVID -19 Impact

According to the bone graft substitute market analysis, the bone graft substitute market was primarily unaffected by COVID-19, even though the pandemic had a short-term impact on market growth because orthopedic procedures, such as bone replacement graft devices, are in high demand due to the subsequent spike in demand for bone-related treatments.