Bone Graft Substitute Market Research Report—Global Forecast till 2030

Bone Graft Substitute Market Research Report: Information By Product Type (Allograft, {Machine allografts, Demineralized Bone Matrix (DBM)}, Bone Graft, Substitute {Synthetic Bone Grafts, Bone Morphogenic Proteins}, Cell-based Matrices), By Application (Spinal Fusion, Joint Reconstruction, Long Bone, Dental, Foot & Ankle), and Region (North America, Europe, Asia-Pacific, and Rest of the World)—Forecast till 2030

ID: MRFR/HC/0689-CR | August 2021 | Region: Global | 126 Pages         

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Bone Graft Substitute Market

Bone Grafts and Substitutes Market is anticipated to acquire a market value of USD 2,121.66 million while thriving at a CAGR of 6.80% by 2030

Segmentation
By Product Type Allograft Bone Graft Substitute Cell-based Matrices
By Application Spinal Fusion Joint Reconstruction Long Bone Dental Foot & Ankle
Key Players
Companies Profiled    ACE Surgical Supply Company    Inc. (US)    BioHorizons (US)    Dentium (South Korea)    Dentsply Sirona (US)    Institut Straumann AG (Switzerland)    Medtronic (Ireland)    Stryker (US)    Zimmer Biomet (US)
Drivers
Market Driving Forces    Rising Incidences of Bones & Joint Disorders to Boost the Market    Growth during the Projection Period
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Bone Graft Substitute Market Overview


The Bone Graft Substitute Market is projected to reach USD 2,121.66 million by 2030 at 6.80% CAGR during the forecast period 2022-2030. Bone grafting is a medical procedure used to repair severe bone fractures. Bone grafts are implantable materials that are used in the surgical process to help with bone healing, bone formation, and osseous reconstruction. A bone substitute is a synthetic, artificial, or biologically organic fusion that can be used instead of autogenous or allogenous bone to treat a bone defect


March 2022


Molecular Matrix, Inc. (MMI), a leader in regenerative medicine polymer technology, is proud to announce the full launch of its Osteo-P® Synthetic Bone Graft Substitute (BGS) for use in the musculoskeletal system. Osteo-P® BGS is made using MMI’s hyper-crosslinked carbohydrate polymer (HCCP) technology platform which has been engineered to optimize the microenvironment for bone repair and regeneration.


Osteo-P® BGS’s natural matrix does not require the addition of a collagen xenograft or other binder to improve handling.


COVID-19 Impact Analysis


Although COVID-19 will have a short-term effect on market growth, the market will largely be unaffected by the pandemic because orthopedic procedures, including bone graft substitute devices, are in high demand due to the subsequent rise in the demand for bone-related treatments. Additionally, many nations have begun easing lockdowns and other COVID-19-related precautions, allowing for the resumed performance of orthopedic procedures.


The situation following the COVID-19 outbreak has improved tremendously since governments worldwide have started to relax norms, giving way to business activities operating once again. Movement restrictions are no longer an issue, which is encouraging companies to now expand their presence in other regions, other than their own.


For instance, in October 2022, CGBio, a South Korean healthcare provider, has procured a firm hold on the sale of its advanced synthetic bone graft material that has clinical uses in spine, orthopedic, trauma and dental applications across North America via a license-out and product supply contract with a U.S. medical device company, Orthofix.


CGBio's material called Novosis, has been approved in South Korea, Mexico, India, and Southeast Asia, and can be described as a recombinant human bone morphogenetic protein-2 bone growth material that is used as a scaffold for the development of a new bone while offering moldable handling.  


Market Dynamics


The growth of biocompatible synthetic bone grafts, an increase in demand for dental bone graft processes, and an increase in road injury and joint disorder incidences are some of the key factors driving market expansion. Bone graft substitutes market growth is being hindered by factors like high surgical costs, risks associated with bone graft procedures, and complications.


THERAVET has developed a new line of calcium-phosphate and biological bone substitutes, BIOCERA-VET. BIOCERA-VET® is a full range of innovative, easy-to-use, efficient & cost-effective bone substitutes indicated in bone surgeries where a bone graft is required and as a palliative alternative in the management of canine osteosarcoma.


Drivers



  • Rising incidence of road injuries and joint disorders


The frequency of traffic accidents is increasing. For instance, the WHO estimates that every year, 1.35 million people die in road accidents and 20 to 50 million people suffer non-fatal injuries. Additionally, the National Trauma Institute estimates that the economic toll of trauma cases in 2014 increased to USD 671 billion, including lost productivity and healthcare costs. There are many ways to treat diseases and injuries with bone grafting. If a fracture has multiple, complex, or poor healing after initial treatment, it may be used. In a diseased joint, it is also used for fusion, which aids in the healing of two bones. Fusion is typically carried out on the spine.


Restraint:



  • Surgery fees are very expensive


The price of a bone graft varies greatly depending on the circumstance and the patient's health. For instance, a single implant region will cost anywhere between USD 300 and USD 800 for simple bone grafting for dental purposes using synthetic bone. Hospitalization is required and adds to the cost of a bone graft operation when a patient's bone material is obtained from various body locations.


Opportunity:



  • The orthopedic care sector has received a lot of investmen


A crucial component of health policy and planning is accurate and comparable estimates of each nation's health spending. They are essential to advancing regional, global, and national health objectives. The WHO published a new report on global health spending on February 20, 2019, which showed that high-income countries saw an increase in health spending of 4% and low- and middle-income countries saw an increase of 6% globally. Less than 40% of primary health care spending is covered by the government. Due to the significant market opportunity for bone graft substitutes, many businesses are entering the space.


Segment Overview


By Product Type


Based on the Product Type, the global Bone Graft Substitute market has been divided into Allograft, {Machine allografts, Demineralized Bone Matrix (DBM)}, Bone Graft Substitute {Synthetic Bone Grafts, Bone Morphogenic Proteins}, Cell-based Matrices. The spinal fusion segment holds the largest share of bone graft substitute market. Allografts come from people other than the recipient of the graft. It is typically sourced from a bone bank and is mainly taken from cadavers who have donated their bone so that it can be used for people who are alive and in need.


By Application


Based on the Application, the global Bone Graft Substitute market is divided into Spinal Fusion, Joint Reconstruction, Long Bone, Dental, Foot & Ankle. The spinal fusion segment will grow the fastest. It's crucial to realize that bone grafts do not perform the spinal fusion or heal the distress in the spine. However, a bone graft creates a setting in which a strong bridge can develop. The spine is supported by a bone graft, which also enables the body to regenerate the bone and fuse the affected section of the spine.


February 2022


Orthofix Medical Inc. (NASDAQ:OFIX), a global medical device company with a spine and orthopedics focus, today announced the full market launch of Opus™ BA, a synthetic bioactive bone graft solution for cervical and lumbar spine fusion procedures.


Opus BA can be used to fill bone voids or gaps in the skeletal system that are not intrinsic to the stability of bony structure. Opus BA acts as a scaffold allowing bone growth across the surface that is reabsorbed and replaced with natural bone during the healing process.


Global Bone Graft Substitute Market Share, by Region, 2021 (%)Global Bone Graft Substitute Market Share, by Region, 2021 (%)


Regional Analysis


By region, the global market has been divided into North America, Europe, Asia-Pacific, and the Rest of the World. Europe accounted for the largest market share. Asia-Pacific is projected to exhibit the highest CAGR during the review period.


October 2022


LifeNet Health is showcasing the most advanced allograft biologics for fusion during the North American Spine Society (NASS) 2022 Annual Meeting in Chicago Oct. 12-14 (Booth #3216). The global leader in allograft solutions and processing technology will feature the growing body of evidence supporting LifeNet Health's solutions for thoracic, cervical, and lumbar fusions — including ViviGen® Cellular Bone Matrix, PliaFX® Prime moldable demineralized fibers, and VertiGraft® structural allografts.


Europe Market


Europe held a large share of the global bone graft substitute market. With increased awareness of bone graft substitutes and rising healthcare costs, Europe has emerged as a significant market. The region has significant growth potential, which will aid in the global market's expansion in the coming years. Countries such as the UK and Germany are expected to make major contributions to the growth of the regional market, which will benefit the industry.


Asia-Pacific Market


The bone graft substitute market is predicted to grow fastest in Asia-Pacific. Due to the presence of developing economies such as India, China, and South Korea as well as the growing potential patient population, the region offers lucrative opportunities for players in the bone graft substitute market. Additionally, it is anticipated that the market will expand during the review period due to the growing geriatric population and rising healthcare spending. The bone graft market is expanding quickly in the Asia-Pacific region owing to research and development initiatives.


Competitive Landscape


The market comprises tier-1, tier-2, and local players. The tier-1 and tier-2 players have reach across the globe with diverse product portfolios. Companies such as Johnson & Johnson Services Inc, Geistlich Pharma, AlloSource, Smith & Nephew, and Integra Lifesciences Holdings Corporation dominate the global Bone Graft Substitute market due to product differentiation, financial stability, strategic developments, and diversified regional presence. The players are focused on investing in research and development. Furthermore, they adopt strategic growth initiatives, such as expansion, product launches, joint ventures, and partnerships, to strengthen their market position and capture a large customer base.


Prominent players in the global Bone Graft Substitute market include Medtronic, AlloSource, Zimmer Biomet Holdings Inc, Stryker, Smith & Nephew, Johnson & Johnson Services Inc, Baxter International Inc, Integra Lifesciences Holdings Corporation, Orthofix Holdings Inc, Geistlich Pharma, SeaSpine.


Scope of the Report


Global Bone Graft Substitute Market, By Product Type




  • Allograft

    • Machine allografts

    • Demineralized Bone Matrix (DBM)




  • Bone Graft Substitute

    • Synthetic Bone Grafts

    • Bone Morphogenic Proteins



  • Cell-based Matrices


Global Bone Graft Substitute Market, By Application



  • Spinal Fusion

  • Joint Reconstruction

  • Long Bone

  • Dental

  • Foot & Ankle

  • Others


Global Bone Graft Substitute Market, By Region




  • North America

    • US

    • Canada

    • Mexico




  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Rest of Europe




  • Asia-Pacific

    • China

    • India

    • Japan

    • Australia and New Zealand

    • Rest of Asia-Pacific




  • Rest of the World

    • South America

    • Middle East

    • Africa




Objectives of the Study


The objectives of the study are summarized in 5 stages. They are as mentioned below:


Market Size and Forecast:


To identify and estimate the market size for the global Bone Graft Substitute market segmented by Hardware, Types, and Applications, by value (in US dollars). Also, to understand the consumption/ demand created by consumers of Bone Graft Substitute during the period of 2020-2030


Market Landscape and Trends:


To identify and infer, the drivers, restraints, opportunities, and challenges for the global Bone Graft Substitute market


Market Influencing Factors:


To find out the factors which are affecting the sales of Bone Graft Substitute among consumers


Impact of COVID-19:


To identify and understand the various factors involved in the global Bone Graft Substitute market affected by the pandemic


Company Profiling:


To provide a detailed insight into the major companies operating in the market. The profiling will include the financial health of the company past 2-3 years with segmental and regional revenue breakup, product offering, recent developments, SWOT analysis, and key strategies.


Intended Audience



  • Bone Graft Substitute producers

  • Raw Material Suppliers

  • Retailers, Wholesalers, and Distributors

  • Governments, Associations, and Industrial Bodies

  • Investors and Trade Experts



Report Scope:

Report Attribute/Metric Details
  Market Size   2030: USD 4.47 Billion
  CAGR   7.86% CAGR (2022-2030)
  Base Year   2021
  Forecast Period   2022-2030
  Historical Data   2020
  Forecast Units   Value (USD Million)
  Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
  Segments Covered   Type, Application
  Geographies Covered   North America, Europe, Asia-Pacific, and Rest of the World (RoW)
  Key Vendors   Medtronic, AlloSource, Zimmer Biomet Holdings Inc, Stryker, Smith & Nephew, Johnson & Johnson Services Inc, Baxter International Inc, Integra Lifesciences Holdings Corporation, Orthofix Holdings Inc, Geistlich Pharma, SeaSpine
  Key Market Opportunities   The orthopedic care sector has received a lot of investment
  Key Market Drivers   Rising incidence of road injuries and joint disorders


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Frequently Asked Questions (FAQ) :

The study period of the global Bone Graft Substitute market is 2022 - 2030

The global Bone Graft Substitute market is growing at a CAGR of 6.80% over the next 10 years

Asia Pacific is expected to register the highest CAGR during 2022 - 2030

Johnson & Johnson Services Inc, Geistlich Pharma, AlloSource, Smith & Nephew, and Integra Lifesciences Holdings Corporation are the major companies operating in the global Bone Graft Substitute market.