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US Herpes Zoster Market

ID: MRFR/HC/16521-CR
100 Pages
Garvit Vyas
December 2023

US Herpes Zoster Market Research Report By End User (Hospitals & Clinics, Diagnostic Centers, Research & Academic Institutes, Home Care Settings, Others) By Diagnosis (Laboratory Testing, Immunofluorescent Microscopy, Real-Time Polymerase Chain Reaction (PCR), Serological Testing, Others) By Route of Administration (Oral, Topical, Others) By Treatment and Prevention (Antiviral Medications, Narcotic Medications, Anti-Inflammatory Medications, Antihistamines, Anticonvulsants, Capsaicin, Numbing Creams, Gels, or Patches, Vaccines, Other... read more

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US Herpes Zoster Market Summary

As per MRFR analysis, the US herpes zoster market Size was estimated at 55.12 USD Million in 2024. The US herpes zoster market is projected to grow from 58.19 USD Million in 2025 to 100.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 5.56% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US herpes zoster market is experiencing growth driven by increased vaccination and treatment advancements.

  • Rising vaccination rates are contributing to a more proactive approach in managing herpes zoster.
  • Advancements in treatment options are enhancing patient outcomes and expanding market potential.
  • Growing awareness and education about herpes zoster are likely leading to higher demand for vaccines and treatments.
  • The increasing incidence of herpes zoster and healthcare policy changes are major drivers of market growth.

Market Size & Forecast

2024 Market Size 55.12 (USD Million)
2035 Market Size 100.0 (USD Million)
CAGR (2025 - 2035) 5.56%

Major Players

GSK (GB), Merck & Co (US), Pfizer (US), Sanofi (FR), AstraZeneca (GB), Bristol-Myers Squibb (US), Novartis (CH), Teva Pharmaceutical Industries (IL)

US Herpes Zoster Market Trends

The herpes zoster market is currently experiencing notable developments, driven by an increasing awareness of the condition and advancements in treatment options. Herpes zoster, commonly known as shingles, results from the reactivation of the varicella-zoster virus, which can lead to painful rashes and complications. The rising incidence of this condition, particularly among older adults, has prompted healthcare providers to focus on prevention and management strategies. Vaccination programs have gained traction, with the introduction of more effective vaccines that aim to reduce the incidence and severity of herpes zoster. This shift in focus towards preventive measures is likely to shape the market dynamics in the coming years. Moreover, the herpes zoster market is influenced by ongoing research and development efforts aimed at improving therapeutic options. Innovative treatments are being explored, including antiviral medications and pain management therapies, which may enhance patient outcomes. The increasing prevalence of herpes zoster, coupled with a growing aging population, suggests a sustained demand for effective interventions. As healthcare systems adapt to these trends, the market is poised for growth, with potential opportunities for stakeholders to invest in new technologies and treatment modalities. Overall, the landscape of the herpes zoster market appears to be evolving, reflecting a commitment to better patient care and improved health outcomes.

Rising Vaccination Rates

There is a noticeable increase in vaccination rates against herpes zoster, particularly among older adults. This trend is driven by heightened awareness of the risks associated with shingles and the availability of effective vaccines. Public health initiatives are promoting vaccination as a key strategy for prevention, which may lead to a decline in herpes zoster cases.

Advancements in Treatment Options

The herpes zoster market is witnessing advancements in treatment options, including new antiviral medications and pain management therapies. These innovations aim to improve patient outcomes and reduce the severity of symptoms. Ongoing research is likely to yield more effective therapies, enhancing the overall management of herpes zoster.

Growing Awareness and Education

There is a growing emphasis on awareness and education regarding herpes zoster. Healthcare providers are increasingly informing patients about the condition, its complications, and the importance of vaccination. This trend may contribute to earlier diagnosis and treatment, ultimately improving health outcomes for affected individuals.

US Herpes Zoster Market Drivers

Rising Public Health Initiatives

Public health initiatives aimed at increasing awareness and prevention of herpes zoster are playing a crucial role in shaping the market. Campaigns promoting vaccination and education about the risks associated with shingles are gaining traction, particularly among healthcare providers and community organizations. These initiatives are likely to enhance the herpes zoster market by encouraging more individuals to seek vaccination and treatment. Furthermore, partnerships between public health agencies and pharmaceutical companies are fostering the development of targeted outreach programs, which may lead to improved vaccination rates and better management of herpes zoster cases across various demographics.

Increasing Incidence of Herpes Zoster

The herpes zoster market is experiencing growth due to the rising incidence of herpes zoster infections in the population. Data indicates that approximately 1 in 3 individuals will develop shingles in their lifetime, with the incidence increasing significantly among older adults. This demographic shift, particularly among those aged 50 and above, is likely to drive demand for vaccines and treatment options. The herpes zoster market is thus positioned to expand as healthcare providers focus on preventive measures and treatment protocols to manage this condition effectively. Furthermore, the increasing prevalence of immunocompromised individuals, due to various health conditions, further contributes to the rising incidence of herpes zoster, necessitating enhanced healthcare strategies and interventions.

Healthcare Policy and Reimbursement Changes

Changes in healthcare policies and reimbursement frameworks are influencing the herpes zoster market. Recent adjustments in insurance coverage for shingles vaccines and treatments have made them more accessible to patients. For instance, the inclusion of the herpes zoster vaccine in preventive care guidelines has led to increased vaccination rates, particularly among older adults. This shift in policy is expected to enhance the herpes zoster market by reducing out-of-pocket costs for patients, thereby encouraging more individuals to seek vaccination and treatment. Additionally, the expansion of Medicare coverage for shingles vaccines has been a pivotal factor in driving market growth, as it directly impacts the affordability and accessibility of these essential healthcare services.

Technological Innovations in Vaccine Development

The herpes zoster market is benefiting from technological innovations in vaccine development. Recent advancements in vaccine formulations and delivery methods have improved the efficacy and safety profiles of shingles vaccines. For example, the introduction of recombinant zoster vaccine (RZV) has shown a remarkable efficacy rate of over 90% in preventing herpes zoster in older adults. Such innovations are likely to enhance patient compliance and acceptance, thereby driving the herpes zoster market forward. Moreover, ongoing research into novel vaccine candidates and adjuvants may further bolster the market by providing additional options for prevention, catering to diverse patient needs and preferences.

Aging Population and Increased Healthcare Utilization

The aging population in the United States is a significant driver of the herpes zoster market. As individuals age, their immune systems weaken, making them more susceptible to herpes zoster infections. This demographic trend is expected to lead to increased healthcare utilization, including vaccinations and treatments for shingles. The herpes zoster market is likely to see a surge in demand as healthcare providers prioritize preventive care for older adults. Additionally, the growing awareness of the importance of vaccination among this age group is anticipated to further stimulate market growth, as more individuals seek to protect themselves from the complications associated with herpes zoster.

Market Segment Insights

By Diagnosis: Real-Time Polymerase Chain Reaction (PCR) (Largest) vs. Serological Testing (Fastest-Growing)

In the US herpes zoster market, the diagnostic segment is primarily dominated by Real-Time Polymerase Chain Reaction (PCR), which holds the largest market share due to its accuracy and rapid results. Laboratory Testing and Immunofluorescent Microscopy also contribute significantly, but Serological Testing is emerging as a notable player with increases in utilization. The growth trends in the diagnosis segment are driven by the rising prevalence of herpes zoster and a growing focus on early diagnosis and treatment. Advancements in PCR technology and serological methods have aided in swift identification of the virus, making the testing process more efficient. The increasing awareness regarding herpes zoster prevention and advancements in laboratory technology support the segment's expansion.

Real-Time Polymerase Chain Reaction (PCR) (Dominant) vs. Serological Testing (Emerging)

Real-Time Polymerase Chain Reaction (PCR) is recognized as the dominant technique in the diagnosis of herpes zoster due to its high sensitivity and specificity in detecting viral DNA. This method allows for quick turnaround times, which is crucial for timely management of patients. In contrast, Serological Testing, while currently an emerging segment, is seeing increased interest for its ability to identify immunological responses against the virus. As healthcare providers emphasize comprehensive diagnostic capabilities, the complementary nature of these two testing methodologies shows a promising competitive landscape within the US herpes zoster market.

By Treatment and Prevention: Vaccines (Largest) vs. Antiviral Medications (Fastest-Growing)

The US herpes zoster market shows diverse segment values under the Treatment and Prevention category, with vaccines holding the largest market share. Antiviral medications, while significant, are currently experiencing the fastest growth due to their critical role in managing herpes zoster outbreaks. Other segments like narcotic medications, anti-inflammatory medications, and capsaicin also contribute to the landscape, but their shares fall behind the aforementioned categories. Growth trends in this segment are closely linked to increasing awareness of herpes zoster and its associated complications. The expansion of vaccination programs and emerging clinical evidence supporting antiviral treatments have created favorable conditions for growth. Additionally, more individuals are seeking effective pain management solutions, spurring the demand for neurological and inflammatory treatments, hence driving the market further upward.

Vaccines: Dominant vs. Antiviral Medications: Emerging

Vaccines are regarded as the dominant force within the Treatment and Prevention segment of the US herpes zoster market. They offer preventive options against shingles, thereby reducing the incidence of herpes zoster and its complications. The awareness surrounding vaccine efficacy has grown, resulting in higher uptake rates among older populations. In contrast, antiviral medications represent an emerging segment; their market presence is gaining momentum primarily due to increasing prescription rates and a greater emphasis on a comprehensive therapeutic approach. Antivirals play a crucial role in treating the condition and minimizing its severity, thus are becoming integral in the overall treatment paradigm, enhancing their market appeal.

By Route of Administration: Oral (Largest) vs. Topical (Fastest-Growing)

The US herpes zoster market is primarily dominated by the oral route of administration, which captures the largest share among the various options available. This segment benefits from the convenience and ease of oral medications, making them a preferred choice for many patients. Additionally, topical applications are seeing increasing acceptance, contributing to a more diverse distribution of market shares within this segment. Growth in the oral segment is driven by rising awareness of herpes zoster and the effectiveness of oral medications in managing symptoms. On the other hand, topical treatments are emerging rapidly due to their localized action and minimal systemic side effects, appealing to patients who prefer non-invasive alternatives. This trend indicates a shifting preference towards diverse therapeutic options in the market.

Oral (Dominant) vs. Topical (Emerging)

The oral segment is currently the dominant force in the US herpes zoster market, offering medications that provide comprehensive systemic relief from symptoms. These products are established and backed by clinical efficacy, sitting well with healthcare professionals' recommendations. In contrast, topical treatments represent an emerging segment that leverages localized healing properties, catering to patients seeking non-invasive solutions. While the oral route is well-trusted and widely utilized, the topical segment's growth reflects changing patient preferences, prompting manufacturers to innovate in topical formulations. This coexistence of dominant oral medications and emerging topical solutions showcases a broadening therapeutic landscape, ultimately enhancing patient choice in managing herpes zoster.

By End User: Hospitals & Clinics (Largest) vs. Home Care Settings (Fastest-Growing)

In the US herpes zoster market, the distribution of market share is significantly influenced by the end user segments. Hospitals & clinics hold the largest share, attributed to their advanced resources and ability to manage complex cases. This segment is followed by diagnostic centers and research & academic institutes, which contribute to the overall market presence by enhancing the capabilities in diagnosis, treatment, and preventive measures. Home care settings are witnessing increased adoption, reflecting a gradual shift towards more personalized healthcare solutions. The growth trends in the end user segments are driven by rising awareness about herpes zoster and the availability of effective therapeutics. Home care settings are emerging as the fastest-growing segment due to the growing preference for at-home treatments and monitoring. Hospitals & clinics remain dominant, yet the increasing investment in telehealth services and home-based care models is reshaping patient management and treatment delivery, creating expansion opportunities across segments.

Hospitals & Clinics (Dominant) vs. Home Care Settings (Emerging)

Hospitals & clinics are the dominant players in the US herpes zoster market, equipped with specialized medical staff and comprehensive treatment protocols. They provide critical infrastructure for managing herpes zoster cases, allowing for effective diagnosis, treatment, and follow-up care. Conversely, home care settings are emerging as a significant segment, offering convenience and personalized care for patients preferring treatment within their home environment. This shift is fueled by the increased demand for home-based healthcare solutions, aging populations, and advancements in telemedicine, making it easier for patients to receive quality care outside of traditional clinical settings.

Get more detailed insights about US Herpes Zoster Market

Key Players and Competitive Insights

The herpes zoster market is characterized by a competitive landscape that is increasingly shaped by innovation, strategic partnerships, and a focus on patient-centric solutions. Key players such as Merck & Co (US), GSK (GB), and Pfizer (US) are actively engaged in enhancing their product offerings and expanding their market presence. Merck & Co (US) has positioned itself as a leader through its robust vaccine portfolio, while GSK (GB) emphasizes research and development to introduce novel therapies. Pfizer (US) is leveraging its extensive distribution network to ensure accessibility, thereby enhancing its competitive edge. Collectively, these strategies contribute to a dynamic market environment where innovation and operational efficiency are paramount.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance responsiveness to market demands. The herpes zoster market appears moderately fragmented, with several players vying for market share. However, the influence of major companies is substantial, as they drive trends in product development and market expansion. This competitive structure suggests that while there is room for smaller entities, the dominance of key players shapes the overall market dynamics.

In October 2025, Merck & Co (US) announced a strategic partnership with a leading biotechnology firm to co-develop a next-generation vaccine targeting herpes zoster. This collaboration is expected to leverage advanced technologies, potentially accelerating the development timeline and enhancing the efficacy of the vaccine. Such strategic moves indicate Merck's commitment to maintaining its leadership position through innovation and collaboration.

In September 2025, GSK (GB) launched a new digital health initiative aimed at improving patient engagement and education regarding herpes zoster. This initiative includes a mobile application designed to provide patients with personalized information and reminders about vaccination schedules. By integrating digital solutions into its strategy, GSK is not only enhancing patient experience but also positioning itself as a forward-thinking player in the market.

In August 2025, Pfizer (US) expanded its manufacturing capabilities in the US to increase the production of its herpes zoster vaccine. This expansion is likely to improve supply chain reliability and meet the growing demand for vaccination, particularly among older adults. Pfizer's focus on enhancing production capacity reflects a strategic response to market needs and underscores the importance of operational efficiency in maintaining competitive advantage.

As of November 2025, the herpes zoster market is witnessing trends that emphasize digitalization, sustainability, and the integration of artificial intelligence in product development and patient management. Strategic alliances are increasingly shaping the competitive landscape, allowing companies to pool resources and expertise. Looking ahead, it appears that competitive differentiation will evolve from traditional price-based strategies to a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize these areas may be better positioned to thrive in an increasingly complex market.

Key Companies in the US Herpes Zoster Market market include

Future Outlook

US Herpes Zoster Market Future Outlook

The Herpes Zoster Market is projected to grow at a 5.56% CAGR from 2024 to 2035, driven by increasing vaccination rates, aging populations, and advancements in treatment options.

New opportunities lie in:

  • Development of telehealth platforms for remote consultations and prescriptions.
  • Expansion of vaccine distribution networks in underserved areas.
  • Investment in R&D for novel antiviral therapies targeting herpes zoster.

By 2035, the herpes zoster market is expected to achieve substantial growth and innovation.

Market Segmentation

US Herpes Zoster Market End User Outlook

  • Hospitals & Clinics
  • Diagnostic Centers
  • Research & Academic Institutes
  • Home Care Settings
  • Others

US Herpes Zoster Market Diagnosis Outlook

  • Laboratory Testing
  • Immunofluorescent Microscopy
  • Real-Time Polymerase Chain Reaction (PCR)
  • Serological Testing
  • Others

US Herpes Zoster Market Route of Administration Outlook

  • Oral
  • Topical
  • Others

US Herpes Zoster Market Treatment and Prevention Outlook

  • Antiviral Medications
  • Narcotic Medications
  • Anti-Inflammatory Medications
  • Antihistamines
  • Anticonvulsants
  • Capsaicin
  • Numbing Creams
  • Gels
  • or Patches
  • Vaccines
  • Others

Report Scope

MARKET SIZE 202455.12(USD Million)
MARKET SIZE 202558.19(USD Million)
MARKET SIZE 2035100.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.56% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies ProfiledGSK (GB), Merck & Co (US), Pfizer (US), Sanofi (FR), AstraZeneca (GB), Bristol-Myers Squibb (US), Novartis (CH), Teva Pharmaceutical Industries (IL)
Segments CoveredDiagnosis, Treatment and Prevention, Route of Administration, End User
Key Market OpportunitiesAdvancements in vaccine technology and increasing awareness drive growth in the herpes zoster market.
Key Market DynamicsRising demand for herpes zoster vaccines drives competitive innovation and regulatory scrutiny in the healthcare sector.
Countries CoveredUS

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FAQs

What is the expected market size of the US Herpes Zoster Market in 2024?

The US Herpes Zoster Market is expected to be valued at 42.12 million USD in 2024.

What is the projected market size of the US Herpes Zoster Market by 2035?

By 2035, the US Herpes Zoster Market is projected to reach a value of 90.42 million USD.

What is the compound annual growth rate (CAGR) for the US Herpes Zoster Market from 2025 to 2035?

The expected CAGR for the US Herpes Zoster Market from 2025 to 2035 is 7.192 percent.

Which are the prominent players in the US Herpes Zoster Market?

Key players in the US Herpes Zoster Market include Novartis, AstraZeneca, Merck, and Eli Lilly among others.

What is the market size for Laboratory Testing in the US Herpes Zoster Market in 2024?

In 2024, the market size for Laboratory Testing in the US Herpes Zoster Market is valued at 10.5 million USD.

How much is the market for Serological Testing expected to grow by 2035?

The market for Serological Testing is expected to grow to 20.0 million USD by 2035.

What is the estimated market value for Real-Time Polymerase Chain Reaction (PCR) in 2024?

The estimated market value for Real-Time Polymerase Chain Reaction (PCR) in 2024 is 8.0 million USD.

What growth rate can be expected for the market during the forecast period?

The market is anticipated to show a growth rate of 7.192 percent during the forecast period from 2025 to 2035.

How is the market for Immunofluorescent Microscopy expected to change by 2035?

The market for Immunofluorescent Microscopy is expected to increase to 10.5 million USD by 2035.

What is the projected value of the Others diagnosis segment in 2024?

The Others diagnosis segment is projected to be valued at 8.02 million USD in 2024.

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