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US Endoprosthesis Market

ID: MRFR/MED/12339-HCR
100 Pages
Garvit Vyas
October 2025

US Endoprosthesis Market Research Report: By Product (Knee, Hip, Shoulder, Elbow, Finger/Hand, Ankle/Foot), By Knee (Primary, Partial, Revision Knee Replacement, Tumor, Custom Made), By Hip (Primary, Partial, Revision Hip Replacement, Tumor, Custom Made), By Shoulder (Primary, Revision Shoulder Replacement, Tumor, Custom Made) and By Elbow (Total Elbow, Radial Head Replacement, Tumor, Custom Made) - Forecast to 2035

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US Endoprosthesis Market Infographic
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US Endoprosthesis Market Summary

As per MRFR analysis, the US endoprosthesis market Size was estimated at 2787.12 USD Million in 2024. The US endoprosthesis market is projected to grow from 3099.28 USD Million in 2025 to 8961.85 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 11.2% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US endoprosthesis market is experiencing robust growth driven by technological advancements and increasing healthcare expenditure.

  • Technological advancements are enhancing the efficacy and safety of endoprosthesis devices.
  • Minimally invasive techniques are gaining traction, leading to shorter recovery times for patients.
  • The orthopedic segment remains the largest, while the dental segment is the fastest-growing in the endoprosthesis market.
  • Rising geriatric population and increased healthcare expenditure are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 2787.12 (USD Million)
2035 Market Size 8961.85 (USD Million)
CAGR (2025 - 2035) 11.2%

Major Players

Stryker Corporation (US), Zimmer Biomet Holdings Inc (US), DePuy Synthes (US), Medtronic plc (IE), Smith & Nephew plc (GB), Boston Scientific Corporation (US), NuVasive Inc (US), Aesculap Implant Systems GmbH (DE)

US Endoprosthesis Market Trends

The endoprosthesis market is currently experiencing notable growth, driven by advancements in medical technology and an increasing prevalence of chronic diseases. Innovations in materials and design are enhancing the performance and longevity of endoprostheses, which are crucial for patients requiring joint replacements or vascular interventions. Furthermore, the aging population in the US is contributing to a higher demand for these medical devices, as older individuals are more likely to require surgical interventions. Regulatory bodies are also playing a pivotal role in ensuring the safety and efficacy of these products, which fosters consumer confidence and encourages market expansion. In addition, the endoprosthesis market is witnessing a shift towards minimally invasive surgical techniques. These approaches not only reduce recovery times but also minimize complications, making them more appealing to both patients and healthcare providers. The integration of digital technologies, such as 3D printing and robotics, is further revolutionizing the production and implantation of endoprostheses. As the market evolves, stakeholders must remain vigilant to emerging trends and adapt to the changing landscape to maintain competitiveness and meet patient needs.

Technological Advancements

Recent innovations in materials and manufacturing processes are enhancing the quality and durability of endoprostheses. The introduction of biocompatible materials and advanced coatings is improving patient outcomes and reducing the risk of complications.

Minimally Invasive Techniques

There is a growing preference for minimally invasive surgical methods in the endoprosthesis market. These techniques offer benefits such as reduced recovery times and lower rates of postoperative complications, appealing to both patients and surgeons.

Regulatory Developments

Regulatory agencies are increasingly focused on the safety and effectiveness of endoprostheses. Stricter guidelines and approval processes are shaping the market, ensuring that only high-quality products reach consumers.

US Endoprosthesis Market Drivers

Rising Geriatric Population

The increasing geriatric population in the US is a pivotal driver for the endoprosthesis market. As individuals age, they often experience degenerative joint diseases, necessitating surgical interventions such as joint replacements. According to the US Census Bureau, by 2030, all baby boomers will be over 65, leading to a projected increase in demand for orthopedic surgeries. This demographic shift is likely to result in a substantial rise in the endoprosthesis market, as older adults are more prone to conditions like osteoarthritis. The market is expected to grow at a CAGR of approximately 6.5% from 2025 to 2030, driven by the need for effective solutions to enhance mobility and quality of life for the aging population.

Increased Healthcare Expenditure

Rising healthcare expenditure in the US is a crucial driver for the endoprosthesis market. With healthcare spending projected to reach $6 trillion by 2027, there is a corresponding increase in funding for surgical procedures, including joint replacements. This financial commitment enables hospitals and clinics to invest in advanced surgical technologies and high-quality endoprosthetic devices. Furthermore, as insurance coverage expands, more patients are likely to seek surgical interventions for joint-related issues, thereby boosting the demand for endoprostheses. The endoprosthesis market is expected to benefit from this trend, as increased healthcare spending correlates with higher adoption rates of innovative medical solutions.

Growing Awareness of Joint Health

The growing awareness of joint health among the US population is driving the endoprosthesis market. Educational campaigns and health initiatives are emphasizing the importance of maintaining joint function and addressing degenerative conditions early. As individuals become more informed about treatment options, including endoprosthetic solutions, the demand for these devices is likely to increase. Additionally, the rise of fitness culture and preventive healthcare is encouraging people to seek medical advice for joint pain and mobility issues. This heightened awareness is expected to contribute to a steady growth trajectory for the endoprosthesis market, as more patients opt for surgical interventions to improve their quality of life.

Technological Innovations in Prosthetics

Technological advancements in prosthetic devices are significantly influencing the endoprosthesis market. Innovations such as 3D printing, smart prosthetics, and biocompatible materials are enhancing the functionality and comfort of endoprostheses. For instance, 3D printing allows for customized implants tailored to individual patient anatomy, which can improve surgical outcomes. The integration of sensors in smart prosthetics provides real-time data on performance and user activity, potentially leading to better rehabilitation processes. The market for these advanced prosthetic technologies is projected to reach $5 billion by 2027, reflecting a growing trend towards personalized and efficient solutions in the endoprosthesis market.

Regulatory Support for Innovative Devices

Regulatory support for innovative medical devices is a significant driver for the endoprosthesis market. The US Food and Drug Administration (FDA) has implemented streamlined processes for the approval of new prosthetic technologies, facilitating quicker access to market for advanced endoprostheses. This regulatory environment encourages manufacturers to invest in research and development, leading to the introduction of cutting-edge products that meet evolving patient needs. As a result, the endoprosthesis market is likely to experience accelerated growth, as new and improved devices become available to healthcare providers and patients. The proactive stance of regulatory bodies in supporting innovation is crucial for the ongoing evolution of the endoprosthesis market.

Market Segment Insights

By Product: Knee (Largest) vs. Shoulder (Fastest-Growing)

The US endoprosthesis market displays a diverse distribution among its product segments. Knee prostheses currently hold the largest market share, driven by high demand due to the prevalence of knee-related disorders and an aging population. Following closely are hip and shoulder prostheses, which are also witnessing significant adoption but lag in comparison to knee devices. Ankle, elbow, and finger/hand options represent a smaller, yet notable, portion of the market, appealing to specific patient needs and conditions. Growth trends in the US endoprosthesis market are being influenced by technological advancements, with innovations in materials and designs enhancing product performance and patient outcomes. The fastest growth in shoulder prostheses can be attributed to the rising awareness of minimally invasive surgical techniques and their benefits in rehabilitation. Demographic shifts, such as an aging population, further drive the demand for hip and knee replacements, while lifestyle changes contribute to an overall increase in the need for orthopedic solutions.

Knee (Dominant) vs. Shoulder (Emerging)

Knee prostheses represent the dominant force in the US endoprosthesis market, characterized by their widespread acceptance and proven effectiveness in alleviating pain and restoring mobility for patients with osteoarthritis and other knee disorders. The demand for knee replacements is fueled by an aging population and increased participation in physical activities that lead to knee injuries. In contrast, shoulder prostheses, while emerging, showcase rapid growth due to the introduction of innovative designs and surgical techniques. These include reverse shoulder arthroplasties, which offer solutions for complex shoulder issues. As surgical expertise improves, shoulder systems are increasingly recognized for their effectiveness, attracting a broader patient base and elevating their position in the market.

By Knee: Primary (Largest) vs. Partial (Fastest-Growing)

In the US endoprosthesis market, the knee segment showcases a diverse distribution among primary, partial, revision, tumor, and custom made replacements. Primary knee replacements currently hold the largest market share, driven by the aging population and increasing incidences of knee-related ailments. This segment benefits from significant advancements in surgical techniques and prosthetic designs, making them a preferred choice among patients and surgeons alike. On the other hand, partial knee replacements are emerging as the fastest-growing segment within the market. Factors contributing to their growth include improved patient outcomes and lower recovery times compared to total knee replacements. As more patients seek less invasive options and reports of successful outcomes circulate, the demand for partially replacing knee joints is likely to surge, reflecting a shift in patient preferences toward innovative procedures.

Primary: Dominant vs. Partial: Emerging

The primary knee replacement segment is characterized by its widespread acceptance and established position in the US endoprosthesis market, offering comprehensive solutions for severe arthritis and joint degeneration. Surgeons favor primary implants due to their reliable long-term performance. In contrast, the partial knee replacement segment is gaining momentum as an innovative and less invasive alternative, appealing particularly to younger and more active patients. These implants preserve more natural anatomy and enable quicker recovery times, thus marking a significant shift in surgical practices and patient selection criteria. As technology progresses, both segments are set to adapt, creating a competitive dynamic that is beneficial for patient care.

By Hip: Primary (Largest) vs. Revision Hip Replacement (Fastest-Growing)

The US endoprosthesis market's hip segment is primarily distributed among five key values: Primary, Partial, Revision Hip Replacement, Tumor, and Custom Made. The Primary segment holds the largest share, reflecting its widespread application and acceptance within orthopedic procedures. Partial replacements and Tumor prostheses also contribute to the market, albeit to a lesser extent, while Custom Made implants represent a niche yet significant segment for specialized cases. Growth trends in the hip segment are driven by the increasing elderly population, rising incidences of hip-related ailments, and advancements in surgical techniques. The Revision Hip Replacement segment is particularly notable for its rapid growth, spurred by the need for corrective surgeries due to complications from initial implants. Innovations in materials and personalized prosthetic designs are further propelling the market forward, offering enhanced patient outcomes and satisfaction.

Primary (Dominant) vs. Revision Hip Replacement (Emerging)

The Primary hip segment is characterized by its dominant market presence, primarily due to the high volume of primary hip replacement surgeries performed annually. This segment benefits from established surgical practices and the availability of a wide range of implant options tailored to various patient needs. On the other hand, the Revision Hip Replacement segment is emerging robustly, driven by a growing population of patients requiring secondary procedures due to wear and failure of initial implants. Despite being smaller in size relative to the Primary segment, the Revision segment is expanding rapidly thanks to advancements in surgical techniques and materials, making it a crucial area of focus for manufacturers aiming to improve patient outcomes and address the complexities associated with revision procedures.

By Shoulder: Primary (Largest) vs. Revision Shoulder Replacement (Fastest-Growing)

The US endoprosthesis market shows a diverse distribution among its shoulder segment values, with Primary shoulder replacements commanding the largest share. This segment is favored due to its effectiveness in treating various shoulder conditions, including rotator cuff tears and arthritis. In contrast, Revision shoulder replacements have emerged as the fastest-growing segment, driven by the increasing number of primary surgeries and the subsequent need for corrective procedures. Growth trends in the shoulder segment are supported by advancements in surgical techniques and implant materials which enhance patient outcomes. Additionally, an aging population is leading to higher incidences of degenerative shoulder diseases, thereby fueling demand for both primary and revision surgeries. The Custom Made and Tumor segments, while significant, are comparatively smaller and cater to specific niche markets within the larger segment framework.

Primary (Dominant) vs. Revision Shoulder Replacement (Emerging)

Primary shoulder replacements dominate the US endoprosthesis market due to their widespread application in treating common shoulder ailments. They are increasingly preferred because of their reliability and success rates, catering primarily to patients with chronic pain and mobility issues. Conversely, Revision shoulder replacements represent an emerging segment, responding to the growing need for reoperation after earlier procedures fail. This segment benefits from innovative therapeutic technologies and materials, ensuring better outcomes and higher patient satisfaction over time. Both segments play crucial roles in enhancing the quality of life for patients, but they cater to different aspects of shoulder health management.

By Elbow: Total Elbow (Largest) vs. Radial Head Replacement (Fastest-Growing)

In the US endoprosthesis market, the Total Elbow segment holds a significant market share, primarily driven by increasing incidences of elbow injuries and degenerative diseases. Radial Head Replacement comes next, showcasing rapid growth due to advancements in surgical techniques and an aging population. The Tumor and Custom Made segments, while essential, occupy a smaller portion of the market but contribute to the overall diversity of elbow solutions available to clinicians. Growth trends are propelled by rising awareness about innovative treatment options, leading to increased surgical procedures. Furthermore, technological advancements in implant design are enhancing patient outcomes and driving adoption. The emphasis on personalized medicine has made Custom Made implants more appealing, catering to patient-specific needs and growing in popularity over the forecast period.

Total Elbow (Dominant) vs. Radial Head Replacement (Emerging)

The Total Elbow segment is characterized by its robust market presence and comprehensive offerings for treating elbow-related ailments, catering mainly to older adults and athletes. This segment's dominance is backed by established manufacturing players who have optimized their product lines for quality and durability. In contrast, the Radial Head Replacement segment is emerging as a favored option among orthopedic surgeons due to its minimal invasive approach and quicker recovery times for patients. Enhanced designs and materials have led to improved implant longevity, making it a popular choice in contemporary elbow surgeries.

Get more detailed insights about US Endoprosthesis Market

Key Players and Competitive Insights

The endoprosthesis market exhibits a dynamic competitive landscape characterized by rapid innovation and strategic maneuvering among key players. Major companies such as Stryker Corporation (US), Zimmer Biomet Holdings Inc (US), and DePuy Synthes (US) are at the forefront, each leveraging distinct strategies to enhance their market positioning. Stryker Corporation (US) focuses on technological advancements, particularly in robotic-assisted surgery, which appears to be a pivotal area for growth. Meanwhile, Zimmer Biomet Holdings Inc (US) emphasizes partnerships with healthcare providers to improve patient outcomes, indicating a trend towards collaborative care models. DePuy Synthes (US) is investing heavily in digital health solutions, suggesting a shift towards integrated healthcare technologies that could redefine patient management.

The business tactics employed by these companies reflect a concerted effort to optimize operations and enhance market presence. Localizing manufacturing has become a common strategy, allowing firms to reduce costs and improve supply chain efficiency. The market structure is moderately fragmented, with several players vying for dominance, yet the collective influence of these key companies shapes a competitive environment that is increasingly focused on innovation and patient-centric solutions.

In October 2025, Stryker Corporation (US) announced the launch of its latest robotic surgical system, which integrates advanced AI capabilities to enhance precision in orthopedic procedures. This strategic move not only reinforces Stryker's commitment to innovation but also positions the company to capture a larger share of the growing demand for minimally invasive surgical options. The introduction of such technology is likely to set new benchmarks in surgical outcomes, thereby influencing competitive dynamics.

In September 2025, Zimmer Biomet Holdings Inc (US) entered into a strategic partnership with a leading telehealth provider to develop a comprehensive digital platform for post-operative care. This initiative underscores the company's focus on enhancing patient engagement and outcomes through technology. By integrating telehealth solutions, Zimmer Biomet is likely to improve recovery processes, which could lead to increased customer loyalty and market share.

In August 2025, DePuy Synthes (US) unveiled a new line of personalized implants designed using 3D printing technology. This innovation not only caters to the growing demand for customized medical solutions but also reflects a broader trend towards personalization in healthcare. The ability to offer tailored solutions may provide DePuy Synthes with a competitive edge, as it aligns with the increasing emphasis on individualized patient care.

As of November 2025, the competitive trends in the endoprosthesis market are increasingly defined by digitalization, sustainability, and the integration of AI technologies. Strategic alliances are becoming more prevalent, facilitating knowledge sharing and resource optimization among companies. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize these areas will be better positioned to thrive in an increasingly complex market.

Key Companies in the US Endoprosthesis Market market include

Industry Developments

Recent developments in the US Endoprosthesis Market reflect significant activities among major players such as Smith and Nephew, Medtronic, and Boston Scientific. Smith and Nephew recently unveiled advancements in their orthopedic solutions aimed at improving patient outcomes, while Medtronic expanded its product line focusing on spinal and orthopedic solutions. In July 2023, Boston Scientific completed its acquisition of a niche market competitor, demonstrating strategic growth in its endoprosthesis division.

The market valuation of companies such as DePuy Synthes and Stryker has also seen notable growth due to increased demand for minimally invasive surgical options, indicated by a rise in procedural volume across the nation.

A significant trend in the US Endoprosthesis Market is the increased focus on innovative technologies, which has stimulated competition among major players, driving forward Research and Development initiatives. Over the past few years, there has been an increased emphasis on sustainability within the medical device sector, highlighting the adaptation of companies like Johnson and Johnson and Zimmer Biomet towards eco-friendly practices. The US Market continues to evolve, presenting lucrative opportunities facilitated by technological advancements and strategic partnerships.

Future Outlook

US Endoprosthesis Market Future Outlook

The Endoprosthesis Market is projected to grow at an 11.2% CAGR from 2024 to 2035, driven by technological advancements, increasing geriatric population, and rising healthcare expenditures.

New opportunities lie in:

  • Development of personalized endoprosthesis solutions leveraging 3D printing technology.
  • Expansion of telehealth services for post-operative care and monitoring.
  • Strategic partnerships with orthopedic clinics for enhanced distribution channels.

By 2035, the endoprosthesis market is expected to achieve substantial growth and innovation.

Market Segmentation

US Endoprosthesis Market Hip Outlook

  • Primary
  • Partial
  • Revision Hip Replacement
  • Tumor
  • Custom Made

US Endoprosthesis Market Knee Outlook

  • Primary
  • Partial
  • Revision Knee Replacement
  • Tumor
  • Custom Made

US Endoprosthesis Market Elbow Outlook

  • Total Elbow
  • Radial Head Replacement
  • Tumor
  • Custom Made

US Endoprosthesis Market Product Outlook

  • Knee
  • Hip
  • Shoulder
  • Elbow
  • Finger/Hand
  • Ankle/Foot

US Endoprosthesis Market Shoulder Outlook

  • Primary
  • Revision Shoulder Replacement
  • Tumor
  • Custom Made

Report Scope

MARKET SIZE 2024 2787.12(USD Million)
MARKET SIZE 2025 3099.28(USD Million)
MARKET SIZE 2035 8961.85(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 11.2% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Stryker Corporation (US), Zimmer Biomet Holdings Inc (US), DePuy Synthes (US), Medtronic plc (IE), Smith & Nephew plc (GB), Boston Scientific Corporation (US), NuVasive Inc (US), Aesculap Implant Systems GmbH (DE)
Segments Covered Product, Knee, Hip, Shoulder, Elbow
Key Market Opportunities Advancements in biocompatible materials enhance patient outcomes in the endoprosthesis market.
Key Market Dynamics Technological advancements and regulatory changes drive innovation and competition in the endoprosthesis market.
Countries Covered US

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FAQs

What is the expected market size of the US Endoprosthesis Market by 2035?

The US Endoprosthesis Market is expected to reach a value of 10.5 USD Billion by the year 2035.

What was the market size of the US Endoprosthesis Market in 2024?

In 2024, the US Endoprosthesis Market was valued at 3.0 USD Billion.

What is the CAGR of the US Endoprosthesis Market from 2025 to 2035?

The US Endoprosthesis Market is projected to have a CAGR of 12.063% during the period from 2025 to 2035.

Which product segment is expected to dominate the US Endoprosthesis Market?

The Knee segment is expected to dominate the market, valued at 3.062 USD Billion by 2035.

How much is the Hip segment valued at in 2024 and what will it be by 2035?

The Hip segment is valued at 0.75 USD Billion in 2024 and is expected to grow to 2.479 USD Billion by 2035.

What is the market value for the Shoulder segment in 2024?

The Shoulder segment is valued at 0.45 USD Billion in the year 2024.

Who are the key players in the US Endoprosthesis Market?

Key players in the market include Smith and Nephew, Boston Scientific, Medtronic, and Johnson and Johnson.

What is the expected value of the Elbow segment by 2035?

The Elbow segment is expected to reach a value of 1.24 USD Billion by 2035.

What opportunities for growth exist in the US Endoprosthesis Market?

Emerging trends such as innovative materials and technology advancements present significant growth opportunities.

What is the projected market size for the Finger/Hand segment in 2035?

The Finger/Hand segment is projected to reach a size of 2.115 USD Billion by 2035.

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