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South America Chiral Chromatography Columns Market

ID: MRFR/HC/49418-HCR
200 Pages
Rahul Gotadki
October 2025

South America Chiral Chromatography Columns Market Research Report By Application (Pharmaceuticals, Biotechnology, Food and Beverage, Environmental Analysis), By Material Type (Amino Acid Derivatives, Cyclodextrins, Cellulose Derivatives, Synthetic Polymers), By Column Type (Preparative Columns, Analytical Columns, Capillary Columns), By End Use (Research Laboratories, Manufacturing Units, Quality Control Departments) and By Regional (Brazil, Mexico, Argentina, Rest of South America)-Forecast to 2035

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South America Chiral Chromatography Columns Market Summary

As per MRFR analysis, the South America chiral chromatography-columns market size was estimated at 170.91 USD Million in 2024. The South America chiral chromatography-columns market is projected to grow from 178.55 USD Million in 2025 to 276.5 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 4.47% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America The South America chiral chromatography-columns market is experiencing robust growth. This growth is driven by technological advancements and increasing demand in pharmaceuticals.

  • Brazil remains the largest market for chiral chromatography-columns, reflecting a strong pharmaceutical sector.
  • Mexico is emerging as the fastest-growing region, indicating a rising interest in biotechnology applications.
  • Technological innovations in analytical chemistry are shaping the market landscape, enhancing efficiency and accuracy.
  • The rising demand for pharmaceuticals and increased research activities are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 170.91 (USD Million)
2035 Market Size 276.5 (USD Million)
CAGR (2025 - 2035) 4.47%

Major Players

Agilent Technologies (US), Thermo Fisher Scientific (US), Merck KGaA (DE), Chiral Technologies (US), Daicel Corporation (JP), Sigma-Aldrich (US), Phenomenex (US), Jiangsu Rixin Pharmaceutical (CN)

South America Chiral Chromatography Columns Market Trends

The chiral chromatography-columns market in South America is currently experiencing notable growth. This growth is driven by increasing demand in various sectors, such as pharmaceuticals, food and beverage, and environmental analysis. The region's expanding pharmaceutical industry, particularly in countries like Brazil and Argentina, is a key factor contributing to this trend. As regulatory standards become more stringent, the need for effective separation techniques to ensure the purity and efficacy of chiral compounds is paramount. Furthermore, advancements in technology and the introduction of innovative products are likely to enhance the capabilities of chiral chromatography, making it an attractive option for laboratories across South America. In addition, the rising awareness of the importance of chiral compounds in drug development and the growing focus on sustainability in analytical practices are influencing the chiral chromatography-columns market. The increasing prevalence of enantiomeric drugs necessitates the use of chiral chromatography for their analysis and production. As environmental concerns gain traction, there is a shift towards greener methodologies, which may further propel the adoption of chiral chromatography techniques. Overall, the market appears poised for continued expansion, with various factors indicating a positive trajectory in the coming years.

Technological Advancements

Recent innovations in chiral chromatography technology are enhancing separation efficiency and resolution. These advancements are likely to attract more users in laboratories, particularly in the pharmaceutical sector, where precision is crucial.

Regulatory Compliance

Stricter regulations regarding drug purity and safety are driving the demand for chiral chromatography-columns. Laboratories are increasingly adopting these techniques to meet compliance standards, particularly in Brazil and Argentina.

Sustainability Initiatives

There is a growing emphasis on sustainable practices within the chiral chromatography-columns market. The shift towards environmentally friendly methodologies is influencing product development and laboratory operations.

South America Chiral Chromatography Columns Market Drivers

Increased Research Activities

Research activities in South America are on the rise, particularly in the fields of chemistry and materials science. This trend is contributing to the growth of the chiral chromatography-columns market, as researchers require advanced separation techniques for their studies. In 2025, research funding in the region is projected to increase by approximately 15%, leading to enhanced capabilities in analytical chemistry. The demand for chiral chromatography-columns is likely to grow as academic and industrial laboratories seek to improve their analytical methodologies. Furthermore, the collaboration between universities and research institutions is expected to drive innovation in chiral separation technologies, thereby benefiting the chiral chromatography-columns market.

Growth in Biotechnology Sector

The biotechnology sector in South America is witnessing rapid advancements, which is positively impacting the chiral chromatography-columns market. With the rise of biopharmaceuticals and biologics, there is a growing need for precise analytical techniques to separate and analyze chiral compounds. The biotechnology market in the region is expected to grow at a CAGR of around 10% from 2025 to 2030, indicating a robust demand for chiral chromatography solutions. This growth is likely to be fueled by increased investments in research and development, as well as collaborations between academic institutions and industry players. Consequently, the chiral chromatography-columns market is poised to benefit from the expanding biotechnology landscape.

Rising Demand for Pharmaceuticals

The chiral chromatography-columns market in South America is experiencing a notable surge in demand. This surge is driven by the pharmaceutical sector. As the region's pharmaceutical industry expands, the need for effective separation techniques to isolate enantiomers becomes increasingly critical. In 2025, the pharmaceutical market in South America is projected to reach approximately $50 billion, with a significant portion allocated to chiral compounds. This growth is likely to propel the chiral chromatography-columns market, as companies seek to enhance their production capabilities and ensure compliance with stringent quality standards. The increasing focus on drug efficacy and safety further emphasizes the importance of chiral chromatography in pharmaceutical applications, thereby fostering market growth.

Emerging Food and Beverage Applications

The food and beverage industry in South America is increasingly recognizing the importance of chiral chromatography for quality control and safety assessments. As consumer awareness regarding food safety rises, manufacturers are compelled to adopt stringent testing methods to ensure product integrity. The chiral chromatography-columns market is likely to see growth as food and beverage companies invest in advanced analytical techniques to detect and quantify chiral compounds. In 2025, the food and beverage sector in South America is anticipated to reach $200 billion, with a growing emphasis on quality assurance. This trend suggests a promising opportunity for the chiral chromatography-columns market to expand its footprint in this sector.

Technological Innovations in Analytical Chemistry

Technological innovations in analytical chemistry are playing a pivotal role in shaping the chiral chromatography-columns market in South America. The introduction of novel materials and advanced column designs is enhancing the efficiency and effectiveness of chiral separations. In 2025, the market for analytical instruments in the region is projected to grow by 12%, driven by the demand for high-performance liquid chromatography (HPLC) systems. These innovations are likely to improve resolution and reduce analysis time, making chiral chromatography more accessible to various industries. As a result, the chiral chromatography-columns market is expected to benefit from these advancements, positioning itself as a key player in the analytical landscape.

Market Segment Insights

By Application: Pharmaceuticals (Largest) vs. Biotechnology (Fastest-Growing)

The application segment of chiral chromatography-columns shows significant market share distribution, with pharmaceuticals as the largest contributor. Pharmaceuticals leverage these columns extensively for drug development and purity testing, ensuring product compliance and safety. Biotechnology, while not the largest, follows closely, driven by increasing research and development activities that highlight the importance of these columns in the production of biologically active compounds. Growth trends indicate a robust upward trajectory for biotechnology as the fastest-growing segment, propelled by advancements in biopharmaceuticals and personalized medicine. The increasing demand for effective separation techniques to enhance drug efficacy is a primary driver. Meanwhile, pharmaceuticals maintain steady growth, aided by regulatory requirements that necessitate high-quality analytical methods in drug manufacturing processes.

Pharmaceuticals (Dominant) vs. Biotechnology (Emerging)

Pharmaceuticals dominate the application segment of chiral chromatography-columns, characterized by rigorous quality control and efficient drug development processes. This sector benefits from regulatory pressures which mandate extensive analytical testing, ensuring that drugs meet stringent safety and efficacy standards. On the other hand, biotechnology is emerging rapidly, fueled by innovations in genetic engineering and the production of monoclonal antibodies. The demand for chiral chromatography in biotechnology is increasing due to the need for precise enantiomer separation that is crucial in the development of biologics. Both segments are strategically important, but their focus areas differ, with pharmaceuticals leaning towards compliance and standardization while biotechnology emphasizes innovation and novel therapeutic approaches.

By Material Type: Amino Acid Derivatives (Largest) vs. Cyclodextrins (Fastest-Growing)

The market for material types within the South America chiral chromatography-columns landscape showcases a distinct distribution, with amino acid derivatives commanding the largest share due to their widespread application in pharmaceutical and research settings. Cyclodextrins, while currently smaller in market size, are rapidly gaining traction, reflecting growing interest in their unique properties that enhance solubility and stability in various applications. Growth trends indicate a diversifying landscape, where amino acid derivatives are bolstered by reliable demand in biotechnology and diagnostics. Conversely, cyclodextrins are the fastest-growing segment driven by increasing needs for drug formulation innovation and the pharmaceutical industry's shift towards more sustainable and efficient processes. The market is supported by advancements in research and development and a rising preference for environmentally friendly materials.

Amino Acid Derivatives (Dominant) vs. Cyclodextrins (Emerging)

Amino acid derivatives dominate the material type segment due to their established functionality, biocompatibility, and effectiveness in enhancing separation processes, making them invaluable in the production of chiral compounds. Their robust application in biopharmaceutical development and quality control continues to bolster their market position. In contrast, cyclodextrins represent an emerging force, characterized by their unique ability to form inclusion complexes that improve drug delivery systems. Their increasing utilization in the food and cosmetic industries, coupled with a growing recognition of their advantages in pharmaceutical applications, positions them as a strong contender in the market, driven by innovation and increased consumer demand.

By Column Type: Analytical Columns (Largest) vs. Preparative Columns (Fastest-Growing)

In the South America chiral chromatography-columns market, Analytical Columns currently command the largest market share, reflecting their widespread application in laboratories for both research and quality control. Preparative Columns, while smaller in share, are witnessing rapid adoption, driven by increasing needs for purification in drug development and environmental testing. This distribution underscores the preference for precise measurements with Analytical Columns versus the emerging demand for efficient separation processes with Preparative Columns. Growth trends indicate a robust expansion in the Preparative Columns segment as pharmaceutical companies accelerate their product development cycles. The rise in biopharmaceutical research also fuels demand, presenting opportunities for manufacturers to innovate and address specific separations challenges. Additionally, advancements in technology and increasing investments in research facilities contribute to the overall positive outlook for both segments. Regulatory requirements further push laboratories to adopt high-performance columns, benefiting both Analytical and Preparative Columns significantly.

Analytical Columns (Dominant) vs. Preparative Columns (Emerging)

Analytical Columns are characterized by their precision and versatility, making them the preferred choice for routine analysis in various sectors, including pharmaceutical and environmental industries. Their ability to provide detailed information about complex mixtures makes them dominant in laboratories across South America. On the other hand, Preparative Columns are gaining traction as emerging solutions for large-scale separation processes, particularly in drug purification and synthesis. These columns focus on efficiency and yield, appealing to companies looking to streamline their workflows. As the market evolves, both segments are poised for growth, but Analytical Columns will continue to lead due to their established presence and reliability, while Preparative Columns are set to capitalize on rising demand for biopharmaceutical applications.

By End-Use: Research Laboratories (Largest) vs. Manufacturing Units (Fastest-Growing)

In the South America chiral chromatography-columns market, Research Laboratories hold the largest market share, attributed to their extensive use of advanced chromatography techniques in drug development and academic research. This segment capitalizes on a growing number of research institutions and initiatives focused on pharmaceuticals and biochemistry, enhancing its position in the market. On the other hand, Manufacturing Units are identified as the fastest-growing segment, driven by increased demand for high-quality chemical products and the rising trend of process automation within the manufacturing sector. The emphasis on regulatory compliance and quality assurance is pushing manufacturers to adopt sophisticated chromatography techniques, thus accelerating growth in this segment.

Research Laboratories: Dominant vs. Manufacturing Units: Emerging

Research Laboratories are the dominant segment in the South America chiral chromatography-columns market, characterized by their heavy reliance on high-performance liquid chromatography (HPLC) for research purposes, which increases precision and efficiency in analysis. They play a fundamental role in applying chromatography for developing new therapies and forensic analysis. In contrast, Manufacturing Units are emerging as a vital player, focusing on integrating innovative chromatography solutions to improve production processes. The need for efficient quality control and compliance with stringent regulations makes this segment essential. As manufacturing technology evolves, these units are increasingly investing in advanced chromatography systems, paving the way for enhanced operational performance and product quality.

Get more detailed insights about South America Chiral Chromatography Columns Market

Key Players and Competitive Insights

The chiral chromatography-columns market in South America is characterized by a dynamic competitive landscape, driven by increasing demand for high-purity compounds in pharmaceuticals and biotechnology. Key players such as Agilent Technologies (US), Thermo Fisher Scientific (US), and Merck KGaA (DE) are strategically positioned to leverage their extensive product portfolios and technological advancements. Agilent Technologies (US) focuses on innovation in analytical instrumentation, while Thermo Fisher Scientific (US) emphasizes its comprehensive solutions for laboratory workflows. Merck KGaA (DE) is enhancing its operational focus on sustainability and green chemistry, which appears to resonate well with current market trends. Collectively, these strategies contribute to a competitive environment that is increasingly oriented towards technological differentiation and sustainability.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance responsiveness to regional demands. The market structure is moderately fragmented, with several players vying for market share. However, the collective influence of major companies is significant, as they set benchmarks for quality and innovation that smaller firms often strive to meet. This competitive structure fosters an environment where collaboration and strategic partnerships are becoming more prevalent, allowing companies to pool resources and expertise.

In October 2025, Agilent Technologies (US) announced the launch of a new line of chiral columns designed specifically for the separation of complex pharmaceutical compounds. This strategic move is likely to enhance their market position by addressing the growing need for specialized solutions in drug development. The introduction of these products not only showcases Agilent's commitment to innovation but also aligns with the increasing regulatory demands for purity in pharmaceuticals.

In September 2025, Thermo Fisher Scientific (US) expanded its distribution network in Brazil, aiming to improve access to its chiral chromatography solutions. This expansion is strategically important as it allows Thermo Fisher to tap into the burgeoning South American market, where demand for advanced analytical solutions is on the rise. By enhancing its local presence, the company is likely to strengthen customer relationships and improve service delivery, which could lead to increased market share.

In August 2025, Merck KGaA (DE) entered into a partnership with a local biotechnology firm in Argentina to co-develop chiral separation technologies. This collaboration is indicative of a broader trend towards strategic alliances that enhance innovation capabilities. By leveraging local expertise, Merck KGaA can accelerate the development of tailored solutions that meet specific regional needs, thereby reinforcing its competitive edge in the market.

As of November 2025, current trends in the chiral chromatography-columns market include a strong emphasis on digitalization, sustainability, and the integration of AI technologies. These trends are reshaping the competitive landscape, as companies increasingly seek to differentiate themselves through innovative solutions rather than price competition. Strategic alliances are playing a crucial role in this evolution, enabling firms to enhance their technological capabilities and market reach. Looking ahead, it appears that the focus will shift towards creating value through innovation and reliable supply chains, positioning companies to better meet the complex demands of the market.

Key Companies in the South America Chiral Chromatography Columns Market market include

Industry Developments

Recent developments in the South America Chiral Chromatography Columns Market have highlighted the significant growth and evolving dynamics of the sector. Companies such as Thermo Fisher Scientific and Agilent Technologies are expanding their product offerings and enhancing their technological capabilities to meet increasing demand from the pharmaceutical and biotech industries, particularly in countries like Brazil and Argentina. In August 2023, Merck KGaA launched new chiral columns that are expected to improve separation effectiveness, thereby addressing the specific needs of the region.

Additionally, Scion Instruments and Waters Corporation are working collaboratively on innovative projects aimed at optimizing laboratory workflows, effectively promoting growth in research activities. The market has also seen increased funding and investments, leading to an overall valuation rise, as organizations prioritize efficient drug discovery processes. In terms of merger and acquisition activity, no recent transactions involving the specified companies have been publicly reported, indicating a current focus on organic growth and internal research initiatives. However, previous years saw significant partnerships and collaborations among local distributors and multinational companies aimed at strengthening market presence and capabilities.

Future Outlook

South America Chiral Chromatography Columns Market Future Outlook

The Chiral Chromatography Columns Market is projected to grow at a 4.47% CAGR from 2024 to 2035, driven by increasing pharmaceutical R&D and regulatory demands.

New opportunities lie in:

  • Expansion of chiral column manufacturing facilities in Brazil.
  • Development of eco-friendly solvents for chiral separations.
  • Partnerships with biotech firms for customized chiral solutions.

By 2035, the market is expected to achieve robust growth, driven by innovation and strategic partnerships.

Market Segmentation

South America Chiral Chromatography Columns Market End-Use Outlook

  • Research Laboratories
  • Manufacturing Units
  • Quality Control Departments

South America Chiral Chromatography Columns Market Application Outlook

  • Pharmaceuticals
  • Biotechnology
  • Food and Beverage
  • Environmental Analysis

South America Chiral Chromatography Columns Market Column Type Outlook

  • Preparative Columns
  • Analytical Columns
  • Capillary Columns

South America Chiral Chromatography Columns Market Material Type Outlook

  • Amino Acid Derivatives
  • Cyclodextrins
  • Cellulose Derivatives
  • Synthetic Polymers

Report Scope

MARKET SIZE 2024170.91(USD Million)
MARKET SIZE 2025178.55(USD Million)
MARKET SIZE 2035276.5(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)4.47% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Agilent Technologies (US)", "Thermo Fisher Scientific (US)", "Merck KGaA (DE)", "Chiral Technologies (US)", "Daicel Corporation (JP)", "Sigma-Aldrich (US)", "Phenomenex (US)", "Jiangsu Rixin Pharmaceutical (CN)"]
Segments CoveredApplication, Material Type, Column Type, End-Use
Key Market OpportunitiesGrowing demand for pharmaceuticals drives innovation in the chiral chromatography-columns market.
Key Market DynamicsRising demand for chiral chromatography-columns driven by pharmaceutical industry growth and regulatory compliance in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Chiral Chromatography Columns Market in 2024?

The South America Chiral Chromatography Columns Market is expected to be valued at 169.5 million USD in 2024.

What will be the market value of the South America Chiral Chromatography Columns Market by 2035?

By 2035, the market is projected to reach a value of 288.0 million USD.

What is the expected CAGR for the South America Chiral Chromatography Columns Market between 2025 and 2035?

The market is expected to grow at a CAGR of 4.937% from 2025 to 2035.

Which application segment is leading the South America Chiral Chromatography Columns Market in 2024?

The Pharmaceuticals segment is leading with a market value of 65.0 million USD in 2024.

What is the market size for Biotechnology applications within the South America Chiral Chromatography Columns Market in 2024?

The Biotechnology application segment is valued at 45.0 million USD in 2024.

What is the expected market value for Brazil in the South America Chiral Chromatography Columns Market by 2035?

Brazil's market value is expected to reach 94.8 million USD by 2035.

How much is the South America Chiral Chromatography Columns Market expected to grow in Mexico from 2024 to 2035?

In Mexico, the market is expected to grow from 30.5 million USD in 2024 to 51.7 million USD by 2035.

What is the projected market size for Environmental Analysis applications in 2035?

The Environmental Analysis segment is projected to reach a market size of 53.0 million USD by 2035.

Who are the key players in the South America Chiral Chromatography Columns Market?

Key players include Scion Instruments, Thermo Fisher Scientific, and Agilent Technologies among others.

What is the expected market growth for the Rest of South America segment from 2024 to 2035?

The Rest of South America segment is expected to grow from 59.0 million USD in 2024 to 100.2 million USD by 2035.

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