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Recombinant Vaccines Market Size

ID: MRFR//4672-HCR | 100 Pages | Author: Rahul Gotadki| October 2024

The global healthcare landscape has a game changer known as the Recombinant Vaccines Market that represents a transformative approach to vaccine development. The basic steps to create recombinant vaccines include gene insertion into host organisms and expression of proteins, which induce an immune reaction in the body. Consequently, this methodology has been instrumental in developing vaccines for various communicable diseases including Hepatitis B, Human Papilloma Virus (HPV) and Influenza.

A particular advantage of these vaccines is their safety profile. The traditional vaccines are often based on attenuated or inactivated forms of pathogens that may pose minor risk of infection to some individuals. Conversely, non-infectious elements are used by recombinant vaccines thereby reducing possibility of side effects. As such, the issue of safety has positioned recombinant vaccinations as the preferred choice for immunization in vulnerable areas such as among babies and those with weakened immunity.

Infectious diseases have been effectively prevented and controlled through the Recombinant Vaccines Market. For example, hepatitis B vaccine, which was among the first recombinant vaccines created has significantly contributed towards lowering the burden of this viral infection worldwide. Similarly, there exist recombinant HPV vaccines that have been helpful/ useful in preventing cervical cancer thereby pointing out how novel forms of immunization bring significant changes in public health.

New emerging infectious threats also drive growth of recombinant vaccine development by market players due to technological advancements. This happened after COVID-19 pandemic struck leading to immediate research innovations that saw creation of recombinant vaccines against SARS-CoV-2 virus. Such interventions have demonstrated high efficacy in prevention severe illness and transmission hence indicating versatility inherent within recombination technology when it comes to managing emerging challenges in public health.

The Recombinant Vaccines Market is present globally with great uptake whether it be developed or developing regions. Global organizations international agencies such like government departments and non-governmental organizations are promoting the use of recombinant vaccines by making sure every person in need gets them especially in order to eradicate disparities related to health. The need for cooperation while distributing these vaccines globally has been highlighted by initiatives aimed at low resource settings such as COVAX.

This might impede accessibility in low-income areas due to high production and distribution costs experienced within the market. As a result, partnerships, technology transfer agreements and exploration of novel production techniques have been put in place to address these challenges with respect to affordability while increasing scalability.

Growth and innovation lie ahead for the Recombinant Vaccines Market. Currently, research efforts are underway to expand the range of infectious diseases targeted by recombinant vaccines. Also important is that vaccine delivery technologies including mRNA platforms have seen tremendous breakthroughs that will eventually shape this field transforming it into one which can offer quick responses towards emerging threats.

Global Recombinant Vaccines Market Overview


Recombinant Vaccines Market Size was valued at USD 0.29 Billion in 2023. The Global Recombinant Vaccines industry is projected to grow from USD 0.36 Billion in 2024 to USD 1.62 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 6.24% during the forecast period (2024 - 2032).


Vaccines that are produced using the recombinant DNA technology or genetic engineering are called recombinant vaccines. 


The recombinant vector vaccine strategy enables triggering of T- cells and antigens, thus generating a strong cell-mediated immune response in the body against that particular immunogen. The market is majorly driven by increasing technical advanced devices, increasing number of regulatory approvals, the high prevalence of infectious diseases, and growing penetration of key market players. 


Furthermore, raising awareness of healthcare, favorable reimbursement policies, increasing innovations in research and development of drugs, and vaccines, as well as rising average income of individuals, are fueling the recombinant vaccines market growth. However, factors such as high cost of vaccines, risks associated with live attenuated vaccines, as well as sore throat irritability after vaccine administration and stringent regulatory policies are likely to hamper the growth of the market. Lack of proper health care infrastructure, as well as awareness regarding pathogen-related diseases in middle-income countries, are a major challenge to the market growth.


Recombinant Vaccines Market Key Players



  • Abiomed

  • Emergent Bio Solutions, Inc.

  • GlaxoSmithKline

  • Johnson & Johnson

  • Sanofi Pasteur SA

  • Serum Institute of India Pvt. Ltd

  • Mitsubishi Tanabe Pharma Corporation

  • Daiichi Sankyo

  • Pfizer, Inc.


Recombinant Vaccines Market Segmentation   


The recombinant vaccines market is segmented on the basis of product type, diseases, and end-user. According to the product, the market is segmented into subunit recombinant vaccines, attenuated recombinant vaccines, and vector recombinant vaccines,


Considering the disease type, the market is segmented into pneumococcal disease, cancer, hepatitis B, influenza, DPT, and others.


On account of the end-user, the market is segmented into hospitals & clinics, pediatrics, adults, veterinary, and others. Veterinary is further segmented to poultry and livestock.


Based on the region the market is segmented into Americas, Europe, Asia Pacific, and the Middle East and Africa. The American region is segmented into North America and South America. Similarly, Europe is segmented into Western Europe and Eastern Europe.


Recombinant Vaccines Market Regional Analysis


Americas is the global leader in recombinant vaccines market owing to increasing advances in molecular biology and genetic engineering techniques as well as increasing prevalence of infectious diseases.  Additionally, factors such as increasing government initiatives and funding for research, development of advanced medical treatment options, and rising demand for technologically advanced treatment are likely to enhance the growth of market in the American region. 


For instance, According to stats presented in the Centers for Disease Control and Prevention report in the year 2017, around 49.9% of the children between the ages of 6 months to 17 years in the U.S. received an influenza vaccine. Due to the alarming rate of diseases associated with opportunistic pathogen developed countries are introducing compulsory immunization program. Raising global burden of cancer has also led a lot of key players to invest their time and money to come up with solutions to curb this problem. For instance, The vaccine therapy with or without trastuzumab as well as GM-CSF vaccine for the treatment of breast cancer is in phases II clinical trial. Green signal from regulatory bodies for these vaccines will further boost up the recombinant vaccines market growth


Europe is the second largest market and holds a healthy share in the market due to major driving factors like availability of advanced treatment facilities, increasing healthcare expenditure along with an alarming rate of cancer and infectious diseases. Furthermore, Lots of established key players in this region export their products to the developing nation. For instance, the European Commission stated that the R&D spending by the pharmaceuticals and biotechnology sectors grew by 8.7% in 2014. This investment in R&D along with the ongoing legislative reforms is expected to have a positive impact on the recombinant vaccines market.


Asia Pacific is expected to be the fastest growing market owing to the faster adaptation of healthcare technology, increasing inpatient pool due to cancer and infectious diseases, government initiatives to increase the healthcare quality, favorable insurance, and reimbursement policies. Key players have set up their regional headquarters and manufacturing plants in Singapore, China, Japan, Korea, and Australia thus, boosting the growth of market. Government is also taking several initiatives to spread awareness in the low-income areas. National Immunization Program In India has helped people below the poverty line get immunized against polio as well as DPT. However, on the other hand, factor such as lack of skilled healthcare professionals may slow down the recombinant vaccines market growth during the forecast period.


The Middle East and Africa is expected to show the least growth in the market due to some major factors such as lack of awareness, limited access and availability of treatment facilities. In the Middle East, United Arab Emirates is the largest market share owing to the development of healthcare industry and rising availability of specialty care centers. However, this area has the possibility to grow during the forecast period as due to increasing outbreak of new opportunistic pathogen associated diseases like Ebola, Zika Virus, and Hepatitis B government along with some key planners have set up their R&D centers in this region.


Intended Audience



  • Pharmaceutical Manufacturers and Suppliers

  • Medical Research Laboratories

  • Research and Development (R&D) Companies

  • Market Research and Consulting Service Providers

  • Potential Investors


Market Segmentation


Recombinant Vaccines Market, by Type



  • Subunit recombinant vaccines

  • Attenuated recombinant vaccines

  • Vector recombinant vaccines


Recombinant Vaccines Market, by Disease



  • Pneumococcal Disease

    • Cancer

    • Hepatitis B

    • Influenza

    • DPT

    • Others




Recombinant Vaccines Market, by End-User



  • Hospitals & Clinics

  • Pediatrics

  • Adults

  • Veterinary

  • Poultry

  • Livestock

  • Others

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