Musculoskeletal System Disorders Market Research Report Information By Type (Rheumatoid Arthritis, Osteoarthritis, Osteoporosis, Psoriatic Arthritis, Ankylosing Spondylitis), Treatment (Biologics, Corticosteroids, Physical Therapy, Protein Therapy, Composite Grafts) and End User (Hospitals and Clinics, Ambulatory Surgical Centers) - Forecast to 2032

Musculoskeletal System Disorders Market Summary

As per MRFR Analysis, the global musculoskeletal system disorders market is projected to reach USD 6.07 Billion by 2032, growing at a CAGR of 6.8% from 2024 to 2032. The rising prevalence of musculoskeletal disorders, which affect 20%-33% of the global population, is a significant driver of market growth. These disorders are particularly common in low- and middle-income countries, necessitating lifelong management. The market is influenced by increasing health insurance reimbursements and a growing geriatric population, alongside lifestyle changes contributing to poor posture. However, high treatment costs and the availability of alternative therapies pose challenges to market expansion.

📌 Key Market Trends & Highlights

Key trends influencing the musculoskeletal system disorders market include rising prevalence and treatment advancements.

• Rheumatoid arthritis is the largest segment, affecting nearly 1% of the global population.
• Osteoporosis is the fastest-growing segment, with over 75 million people affected in Europe, the US, and Japan.
• Biologics are the fastest-growing treatment segment, driven by increased FDA approvals.
• The Americas represent the largest regional market due to high prevalence and a robust healthcare system.

📊 Market Size & Forecast

Market Size by 2032: USD 6.07 Billion

CAGR from 2024 to 2032: 6.8%

Largest Segment: Rheumatoid Arthritis

Fastest Growing Segment: Osteoporosis

🏢 Major Players

AB Science (France), Amgen Inc. (US), AstraZeneca (UK), Eisai Co., Ltd (Japan), GlaxoSmithKline PLC (UK)

The number of musculoskeletal system disorder cases is increasing globally, fueling musculoskeletal system disorder market growth. Musculoskeletal system disorders are the second-highest contributor to global disability and an estimated 20%–33% of people across the globe live with a painful musculoskeletal condition.

Musculoskeletal disorders are most common in low- and middle-income countries and these disorders require lifelong care to manage.

Musculoskeletal System Disorders Market Influencer

Rising prevalence of musculoskeletal disorders and increasing reimbursement offered to patients by health insurance providers.

Musculoskeletal System Disorders Market Drivers

• Growing global geriatric population.

• Change in lifestyle habits leading to bad posture, which is increasing the prevalence of musculoskeletal system disorders.

• Increasing research and development of new drugs to treat musculoskeletal disorders. For instance, in 2017–2018, the National Institute of Health Research (NIHR) spent approximately USD 13.46 million (GBP 11.1 million) on research on musculoskeletal disorders.

• Rising prevalence of work-related musculoskeletal disorders. For example, the prevalence in the fiscal year 2017–2018 was about 469,000 in the UK.

• Rising awareness of advanced treatment for musculoskeletal disorders.

• Launch of new medication to manage the symptoms of chronic musculoskeletal system disorders.

Musculoskeletal System Disorders Market Restraints

• High treatment costs.

• Availability of alternative therapies such as traditional medicine and physiotherapy

• Need for specialized equipment to diagnose and treat musculoskeletal system disorders.

Musculoskeletal System Disorders Market Segment Insights

Musculoskeletal System Disorders Type Insights

• Rheumatoid Arthritis: The largest segment of the musculoskeletal system disorder market, rheumatoid arthritis afflicts almost 1% of the entire global population and is three times as likely to afflict women than men.

• Osteoarthritis: This disorder generally afflicts elderly people. As of 2018, about 9.6% of men and 18% of women over 60 had symptomatic osteoarthritis worldwide and over a quarter of those afflicted could not perform daily activities.

• Osteoporosis: The fastest-growing segment, over 75 million people suffer from osteoporosis in Europe, the US, and Japan. This number is growing in developing countries and the disorder is responsible for millions of fractures worldwide. By 2050, osteoporosis is expected to be responsible for a 310% increase in hip fractures for men and a 240% increase for women, as compared to rates in 1990.

• Psoriatic Arthritis: This autoimmune disorder afflicts roughly 3 out of every 10 individuals who have psoriasis. With over 100 million people afflicted globally with psoriasis, psoriatic arthritis afflicts almost 30 million individuals.

• Ankylosing Spondylitis: The tendency to develop this condition is genetic, with males twice to three times more likely to be afflicted than women.

• Fibromyalgia: A very common ailment, about 80%–90% of sufferers of fibromyalgia are women.

• Others: This segment covers musculoskeletal disorders such as tendinitis and carpal tunnel syndrome.

Musculoskeletal System Disorders Treatment Insights

• Biologics: The fastest-growing segment, biologics find increasing application in the treatment of rheumatoid arthritis. A rise in the number of FDA approvals for biologics to treat musculoskeletal system disorders is a key factor for the growth of the segment.

• Corticosteroids: The largest segment, corticosteroids are the preferred treatment for many musculoskeletal system disorders as they reduce inflammation and suppress immune system activity.

• Physical Therapy: Used to manage almost all chronic musculoskeletal system disorders, physical therapy is prescribed in conjunction with medication.

• Extracorporeal Shock Wave Therapy: Used to manage pain, this therapy excels in providing fast-acting relief without the use of painkillers. Used extensively in managing musculoskeletal system disorders.

• Protein Therapy: A novel method used to combat several musculoskeletal system disorders; it involves the ingestion of protein via changes in diet and artificially produced proteins.

• Synthetic Bone Graft: An expensive and complex treatment option, synthetic bone grafts have been used to replace bones made too brittle by osteoporosis and other musculoskeletal system disorders.

• Composite Grafts: Used for several bone replacement and repair procedures.

• Demineralized Bone Matrix: The treatment method is used in bone transplants where the biological activity of the graft is more important than its mechanical properties.

• Others: This segment covers alternative treatment methods such as gene therapy and chiropractic care.

Musculoskeletal System Disorders End User Insights

• Hospitals and Clinics: The largest segment, hospitals and clinics are usually the primary points for diagnosis, treatment, and rehabilitation of individuals afflicted with musculoskeletal system disorders. Growing awareness and increasing efficiency of musculoskeletal system disorder treatment are projected to drive the growth of this segment during the forecast period.

• Ambulatory Surgical Centers: A small segment, these centers provide immediate pain relief and rudimentary surgical care.

• Others: This segment includes home care and senior citizen centers.

Musculoskeletal System Disorders Regional Insights

• Americas: The largest regional market, the prevalence of musculoskeletal system disorders is high in the Americas; the region also has a well-established healthcare industry.

• Europe: An increasing geriatric population is leading to a rise in the number of musculoskeletal system disorder cases.

• Asia-Pacific: The fastest-growing regional market, Asia-Pacific is seeing a surge in the number of people afflicted with musculoskeletal system disorders due to bad posture brought on by lifestyle changes, aging, and genetic predisposition.

• Middle East & Africa: The smallest market due to limited healthcare infrastructure and a very young population.

Musculoskeletal System Disorders Market Top Key Players

• AB Science (France)


• AbGenomics International, Inc. (US)


• Alder BioPharmaceuticals,Inc. (US)


• Amgen Inc. (US)


• Lexicon Pharmaceuticals, Inc. (US)


• LG Chem (South Korea)


• OrthoTrophix, Inc. (US)


• Tarsa Therapeutics, Inc. (US)


• PhytoHealth Corporation (Taiwan)


• Eisai Co., Ltd (Japan)


• Astellas Pharma Inc. (Japan)


• AstraZeneca (UK)


• Baxter (US)


• GlaxoSmithKline PLC (UK)

Report Attribute/Metric	Details
Market Size	USD 6.07 Billion
CAGR	6.80%
Base Year	2023
Forecast Period	2024-2032
Historical Data	2022
Forecast Units	Value (USD Billion)
Report Coverage	Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Segments Covered	Type, Treatment, End User
Geographies Covered	North America, Europe, Asia-Pacific, and Rest of the World (RoW)
Key Vendors	AB Science (France), AbGenomics International, Inc. (US), Alder BioPharmaceuticals,Inc. (US), Amgen Inc. (US), Lexicon Pharmaceuticals, Inc. (US), LG Chem (South Korea), OrthoTrophix, Inc. (US), Tarsa Therapeutics, Inc. (US), PhytoHealth Corporation (Taiwan), Eisai Co., Ltd (Japan), Astellas Pharma Inc. (Japan), AstraZeneca (UK), Baxter (US), GlaxoSmithKline PLC (UK)
Key Market Opportunities	New product launches and R&D Amongst major key Players
Key Market Drivers	·  Growing global geriatric population ·  Change in lifestyle habits leading to bad posture ·  Increasing research and development of new drugs to treat musculoskeletal disorders. ·  Rising prevalence of work-related musculoskeletal disorders. ·  Rising awareness of advanced treatment for musculoskeletal disorders. ·  Launch of new medication to manage the symptoms of chronic musculoskeletal system disorders.