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    Liver Cancer Market

    ID: MRFR/HC/24595-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Liver Cancer Market Research Report By Stage of Liver Cancer (Early Stage, Intermediate Stage, Advanced Stage), By Treatment Type (Surgery, Radiation Therapy, Chemotherapy, Targeted Therapy, Immunotherapy), By Type of Liver Cancer (Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, Fibrolamellar Carcinoma, Hepatoblastoma) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Liver Cancer Market Infographic
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    Liver Cancer Market Summary

    As per MRFR analysis, the Liver Cancer Market Size was estimated at 1.943 USD Billion in 2024. The Liver Cancer industry is projected to grow from 2.077 USD Billion in 2025 to 4.053 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 6.91 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Liver Cancer Market is experiencing transformative growth driven by innovative therapies and increasing awareness.

    • The emergence of targeted therapies is reshaping treatment paradigms in the liver cancer market.
    • Advancements in diagnostic technologies are enhancing early detection and patient outcomes, particularly in North America.
    • The focus on personalized medicine is gaining traction, especially in the advanced stage segment, which is the fastest-growing.
    • Increasing incidence of liver cancer and rising awareness through screening programs are key drivers propelling market expansion.

    Market Size & Forecast

    2024 Market Size 1.943 (USD Billion)
    2035 Market Size 4.053 (USD Billion)
    CAGR (2025 - 2035) 6.91%

    Major Players

    Bristol-Myers Squibb (US), Roche (CH), Merck & Co. (US), AstraZeneca (GB), Gilead Sciences (US), Novartis (CH), Eli Lilly and Company (US), Amgen (US), Bayer (DE)

    Liver Cancer Market Trends

    The Liver Cancer Market is currently experiencing a dynamic evolution, driven by advancements in treatment modalities and increasing awareness of the disease. The rise in liver cancer incidences, attributed to factors such as hepatitis infections and alcohol consumption, has prompted a surge in research and development efforts. Pharmaceutical companies are focusing on innovative therapies, including targeted treatments and immunotherapies, which appear to enhance patient outcomes. Furthermore, the integration of technology in diagnostics, such as imaging techniques and biomarker identification, is likely to improve early detection rates, thereby influencing treatment decisions and overall market growth. In addition to therapeutic advancements, the Liver Cancer Market is witnessing a shift towards personalized medicine. This approach tailors treatment plans based on individual patient profiles, which may lead to more effective interventions. The growing emphasis on patient-centric care is fostering collaborations between healthcare providers and research institutions, potentially accelerating the development of novel therapies. As the market continues to evolve, stakeholders must remain vigilant to emerging trends and adapt strategies accordingly to navigate the complexities of this landscape.

    Emergence of Targeted Therapies

    The Liver Cancer Market is increasingly characterized by the emergence of targeted therapies. These treatments focus on specific molecular targets associated with liver cancer, potentially leading to improved efficacy and reduced side effects. As research progresses, the development of these therapies may reshape treatment paradigms, offering new hope for patients.

    Advancements in Diagnostic Technologies

    Advancements in diagnostic technologies are playing a crucial role in the Liver Cancer Market. Enhanced imaging techniques and biomarker discovery are facilitating earlier detection of liver cancer, which is essential for effective treatment. This trend suggests a shift towards more proactive management of the disease.

    Focus on Personalized Medicine

    The focus on personalized medicine is gaining traction within the Liver Cancer Market. Tailoring treatment strategies to individual patient characteristics may enhance therapeutic outcomes. This trend indicates a broader movement towards patient-centered care, which could redefine treatment approaches in the coming years.

    Liver Cancer Market Drivers

    Advancements in Treatment Modalities

    Innovations in treatment modalities are significantly influencing the Liver Cancer Market. The development of targeted therapies and immunotherapies has transformed the treatment landscape, offering new hope for patients. For instance, the introduction of sorafenib and regorafenib has provided effective options for advanced liver cancer. Furthermore, ongoing clinical trials are exploring novel agents that may enhance treatment efficacy. The market is expected to witness substantial growth as these advancements become more widely adopted. As a result, pharmaceutical companies are increasingly investing in research and development to bring forth new therapies, thereby driving the Liver Cancer Market forward.

    Increasing Incidence of Liver Cancer

    The rising incidence of liver cancer is a primary driver of the Liver Cancer Market. According to recent statistics, liver cancer cases have been steadily increasing, with an estimated 1 million new cases projected by 2025. This surge is attributed to various factors, including the prevalence of hepatitis B and C infections, alcohol consumption, and obesity. As awareness of liver cancer grows, healthcare systems are compelled to enhance their diagnostic and treatment capabilities. Consequently, this trend is likely to stimulate demand for innovative therapies and technologies within the Liver Cancer Market, as stakeholders seek to address the escalating burden of this disease.

    Rising Awareness and Screening Programs

    The growing awareness of liver cancer and the implementation of screening programs are pivotal in shaping the Liver Cancer Market. Public health initiatives aimed at educating populations about risk factors and symptoms are leading to earlier detection and treatment. Countries are increasingly adopting screening protocols, particularly for high-risk groups, which is likely to enhance patient outcomes. This proactive approach not only improves survival rates but also drives demand for diagnostic tools and treatment options. As awareness continues to rise, the Liver Cancer Market is expected to expand, with stakeholders focusing on developing effective screening methodologies.

    Regulatory Support for Innovative Therapies

    Regulatory bodies are increasingly supporting the development of innovative therapies for liver cancer, which is a crucial driver for the Liver Cancer Market. Initiatives such as expedited approval processes for breakthrough therapies are encouraging pharmaceutical companies to invest in research and development. This regulatory environment fosters innovation, allowing for the rapid introduction of new treatment options. As a result, the market is likely to experience a surge in novel therapies that address unmet medical needs. The collaboration between regulatory agencies and industry stakeholders is essential for advancing the Liver Cancer Market and improving patient care.

    Growing Investment in Healthcare Infrastructure

    The expansion of healthcare infrastructure is a significant factor influencing the Liver Cancer Market. As countries invest in healthcare systems, there is an increased capacity for cancer treatment and management. This investment includes the establishment of specialized cancer centers and the enhancement of diagnostic facilities. Improved access to healthcare services is likely to facilitate early diagnosis and treatment of liver cancer, ultimately leading to better patient outcomes. Furthermore, as healthcare systems evolve, there is a growing emphasis on integrating advanced technologies into treatment protocols, which will further drive the Liver Cancer Market.

    Market Segment Insights

    By Stage of Liver Cancer: Early Stage (Largest) vs. Advanced Stage (Fastest-Growing)

    In the Liver Cancer Market, the distribution among stages reveals a significant presence of early-stage liver cancer patients, who constitute the largest share of the market. This stage benefits from early detection and treatment options, allowing for a more favorable prognosis and extensive therapeutic options. Meanwhile, intermediate and advanced stages show a surge as access to predictive diagnostics advances, recognizing previously undetected cases, thus expanding the market further. Growth trends in this segment are fueled by increasing awareness and advancements in diagnostic technologies, enabling early detection. Emerging therapies and research into targeted treatments for advanced stages promise to improve outcomes and encourage investment in these areas. The demand for improved treatment protocols and supporting infrastructure drives market expansion, making research and development a focal point for growth in the coming years.

    Early Stage (Dominant) vs. Advanced Stage (Emerging)

    The early stage of liver cancer holds a dominant position in the market, primarily due to its high potential for successful treatment and management. Patients at this stage are often candidates for curative therapies, leading to a focus on prevention and early diagnosis strategies. On the other hand, the advanced stage of liver cancer is steadily emerging, driven by a rise in late-stage diagnoses spurred by increased screening and awareness campaigns. This stage presents unique challenges, requiring more complex management strategies and innovative treatment modalities. Emerging therapies, including targeted agents and immunotherapy, are significantly influencing the landscape, marking a shift in how advanced liver cancer is approached. The intersection of these two stages highlights the flux in treatment approaches and the need for ongoing research.

    By Treatment Type: Surgery (Largest) vs. Immunotherapy (Fastest-Growing)

    In the Liver Cancer Market, the treatment type segment is characterized by a varied distribution of market shares among key modalities. Surgery has established itself as the dominant approach due to its effectiveness in early-stage liver cancer, accounting for a significant portion of the treatment market. Radiation therapy, chemotherapy, targeted therapy, and immunotherapy follow, with each modality holding unique positions based on treatment protocols and patient needs. Immunotherapy has gained attention for its potential among advanced liver cancer patients, marking a shift towards more personalized treatment solutions.

    Surgery (Dominant) vs. Immunotherapy (Emerging)

    Surgery remains the dominant treatment for liver cancer, particularly for patients diagnosed in early stages where resection or transplantation is feasible. It is favored for its potential to offer a cure, leading to high survival rates. However, with advancements in cancer research, immunotherapy has emerged as an innovative treatment option, showing promise in improving outcomes for patients with advanced liver cancer. This approach harnesses the body's immune system to target cancer cells, and its rapid development reflects a shift in treatment paradigms. The growing clinical evidence supporting immunotherapy, coupled with ongoing research and development, positions it as a future key player in the liver cancer treatment landscape.

    By Type of Liver Cancer: Hepatocellular Carcinoma (Largest) vs. Intrahepatic Cholangiocarcinoma (Fastest-Growing)

    The liver cancer market is predominantly characterized by Hepatocellular Carcinoma (HCC), which holds the largest market share among all liver cancer types. It is known for its prevalence and is often the first type that comes to mind when discussing liver cancers. Intrahepatic Cholangiocarcinoma (ICC) is gaining traction, showing a rapidly growing market share due to an increase in awareness and improved diagnostic techniques. As healthcare providers enhance their focus on early detection, ICC's prominence continues to rise, contributing to its status as the fastest-growing type in the segment. Growth trends indicate a significant shift towards personalized medicine and targeted therapies for both Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. Factors driving this segment include an aging population, increased alcohol consumption, and rising hepatitis virus infections, especially in endemic regions. Furthermore, advancements in research methodologies and treatment regimens are expected to offer substantial growth opportunities in the coming years. The ongoing focus on enhancing treatment efficacy and patient outcomes will continue to shape the market landscape for these liver cancer types.

    Hepatocellular Carcinoma (Dominant) vs. Intrahepatic Cholangiocarcinoma (Emerging)

    Hepatocellular Carcinoma (HCC) dominates the liver cancer segment due to its higher incidence rates and established treatment protocols. Patients suffering from HCC benefit from a range of therapeutic options, including surgery, liver transplantation, and targeted therapies, which have been tailored over years of clinical practice. The rising prevalence of liver diseases adds to the market presence of HCC. In contrast, Intrahepatic Cholangiocarcinoma (ICC) is emerging as a significant concern due to its challenging diagnosis and aggressive nature. ICC is often diagnosed at later stages, leading to limited treatment options; however, the increase in research initiatives and innovative therapies are expected to highlight its importance in the market. As awareness grows regarding ICC's risk factors and symptoms, coupled with new treatment options, it is poised for growth, reflecting a shift in market focus.

    Get more detailed insights about Liver Cancer Market

    Regional Insights

    North America : Leading Innovation and Research

    North America is the largest market for liver cancer treatments, accounting for approximately 45% of the global market share. The region benefits from advanced healthcare infrastructure, high R&D investments, and a growing prevalence of liver cancer, driven by factors such as obesity and hepatitis infections. Regulatory support from agencies like the FDA further catalyzes market growth, facilitating faster approvals for innovative therapies. The United States is the primary contributor, with significant involvement from key players like Bristol-Myers Squibb, Merck & Co., and Gilead Sciences. The competitive landscape is characterized by a focus on immunotherapy and targeted therapies, with ongoing clinical trials and collaborations enhancing treatment options. Canada also plays a vital role, contributing to research and development efforts in the region.

    Europe : Emerging Market with Growth Potential

    Europe is witnessing significant growth in the liver cancer market, holding approximately 30% of the global share. The region's growth is driven by increasing awareness of liver cancer, advancements in treatment options, and supportive regulatory frameworks. Countries like Germany and France are leading the market, with initiatives aimed at improving early diagnosis and treatment accessibility, which are crucial for enhancing patient outcomes. Germany stands out as a key player, with a robust healthcare system and a strong presence of pharmaceutical companies like Roche and Bayer. The competitive landscape is evolving, with a focus on personalized medicine and innovative therapies. Collaborative efforts among European nations to standardize treatment protocols are also enhancing market dynamics, making Europe a promising region for liver cancer treatment advancements.

    Asia-Pacific : Rapidly Growing Market Segment

    The Asia-Pacific region is rapidly emerging as a significant player in the liver cancer market, accounting for about 20% of the global market share. The growth is primarily driven by rising liver cancer incidence rates, particularly in countries like China and India, where lifestyle changes and viral hepatitis are prevalent. Increased healthcare spending and government initiatives to improve cancer care are also contributing to market expansion. China is the largest market in the region, with a growing number of clinical trials and a focus on innovative treatment options. The competitive landscape includes both local and international players, with companies like AstraZeneca and Novartis actively participating. The region's diverse healthcare systems and varying regulatory environments present both challenges and opportunities for market players, making it a dynamic landscape for liver cancer treatments.

    Middle East and Africa : Untapped Potential and Challenges

    The Middle East and Africa region represents an emerging market for liver cancer treatments, holding approximately 5% of the global market share. The growth is hindered by limited healthcare infrastructure and access to advanced therapies. However, increasing awareness of liver cancer and government initiatives aimed at improving healthcare access are driving demand. Countries like South Africa and the UAE are leading the way in adopting new treatment protocols and enhancing patient care. South Africa is a key player in the region, with a growing number of healthcare facilities focusing on oncology. The competitive landscape is characterized by a mix of local and international companies, with efforts to introduce innovative therapies. Despite challenges such as economic disparities and regulatory hurdles, the region shows promise for future growth in liver cancer treatment options.

    Key Players and Competitive Insights

    The Liver Cancer Market is currently characterized by a dynamic competitive landscape, driven by increasing incidences of liver cancer globally and a growing demand for innovative treatment options. Key players such as Bristol-Myers Squibb (US), Roche (CH), and Merck & Co. (US) are strategically positioned to leverage their extensive research and development capabilities. Bristol-Myers Squibb (US) focuses on immunotherapy advancements, while Roche (CH) emphasizes personalized medicine through biomarker-driven therapies. Merck & Co. (US) is enhancing its portfolio with combination therapies, indicating a collective shift towards more targeted and effective treatment modalities that shape the competitive environment.

    In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The Liver Cancer Market appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies is significant, as they engage in strategic collaborations and partnerships to bolster their market presence and drive innovation.

    In August 2025, Roche (CH) announced a collaboration with a leading biotechnology firm to develop a novel liver cancer therapy that utilizes gene editing technology. This strategic move is likely to position Roche at the forefront of cutting-edge treatment options, potentially revolutionizing the therapeutic landscape for liver cancer patients. The partnership underscores Roche's commitment to innovation and its proactive approach to addressing unmet medical needs in the liver cancer domain.

    In September 2025, Merck & Co. (US) launched a clinical trial for a new combination therapy aimed at advanced liver cancer. This initiative reflects Merck's strategy to enhance treatment efficacy through synergistic drug combinations, which may lead to improved patient outcomes. The trial's results could significantly impact Merck's market positioning, as successful outcomes would reinforce its reputation as a leader in oncology.

    In October 2025, Bristol-Myers Squibb (US) expanded its global reach by entering into a strategic partnership with a prominent Asian pharmaceutical company. This collaboration aims to enhance access to its liver cancer therapies in emerging markets, indicating a strategic focus on regional expansion. Such partnerships are crucial for tapping into new patient populations and addressing the rising burden of liver cancer in these regions.

    As of October 2025, current competitive trends in the Liver Cancer Market include a pronounced emphasis on digitalization, sustainability, and the integration of artificial intelligence in drug development processes. Strategic alliances are increasingly shaping the landscape, enabling companies to pool resources and expertise. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition towards a focus on innovation, technological advancements, and supply chain reliability, as companies strive to meet the complex demands of the liver cancer treatment market.

    Key Companies in the Liver Cancer Market market include

    Industry Developments

    • Q2 2024: CStone Announces NMPA Approval of Sugemalimab for the Treatment of Unresectable or Metastatic Hepatocellular Carcinoma CStone Pharmaceuticals received approval from China's National Medical Products Administration (NMPA) for sugemalimab, an anti-PD-L1 antibody, for the treatment of unresectable or metastatic hepatocellular carcinoma, marking a significant regulatory milestone in the liver cancer market.
    • Q2 2024: Genoscience Pharma raises €20M to advance liver cancer drug into phase 2 Genoscience Pharma secured €20 million in funding to support the phase 2 clinical development of its lead candidate, GNS561, for the treatment of advanced liver cancer.
    • Q2 2024: Exelixis Announces FDA Approval of CABOMETYX® (cabozantinib) for Previously Untreated Advanced Hepatocellular Carcinoma Exelixis received FDA approval for CABOMETYX® (cabozantinib) as a first-line treatment for patients with advanced hepatocellular carcinoma, expanding its indications in the U.S. market.
    • Q2 2024: AstraZeneca and Daiichi Sankyo Receive FDA Priority Review for Datopotamab Deruxtecan in Advanced Liver Cancer AstraZeneca and Daiichi Sankyo announced that the FDA has granted Priority Review to their antibody-drug conjugate, datopotamab deruxtecan, for the treatment of patients with advanced liver cancer.
    • Q3 2024: Bayer launches new manufacturing facility for liver cancer drug Stivarga in Germany Bayer opened a new manufacturing facility in Germany dedicated to the production of Stivarga, a key therapy for advanced liver cancer, to meet growing global demand.
    • Q3 2024: Eisai and Merck Expand Partnership to Develop Lenvima for Early-Stage Liver Cancer Eisai and Merck announced an expansion of their partnership to include the development of Lenvima (lenvatinib) for early-stage liver cancer, aiming to broaden its clinical applications.
    • Q3 2024: HepaRegeniX Raises €30 Million in Series C Financing to Advance Liver Cancer Pipeline HepaRegeniX closed a €30 million Series C financing round to accelerate the clinical development of its proprietary kinase inhibitors for the treatment of liver cancer.
    • Q4 2024: Roche Receives EMA Approval for Tecentriq in Combination with Avastin for Advanced Liver Cancer Roche obtained European Medicines Agency (EMA) approval for the combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) as a first-line treatment for patients with advanced hepatocellular carcinoma.
    • Q4 2024: Innovent Biologics and Eli Lilly Announce Strategic Partnership to Co-Develop Sintilimab for Liver Cancer Innovent Biologics and Eli Lilly entered a strategic partnership to co-develop and commercialize sintilimab, an anti-PD-1 antibody, for the treatment of liver cancer in global markets.
    • Q1 2025: Gilead Sciences Acquires MiroBio to Bolster Liver Cancer Immunotherapy Pipeline Gilead Sciences completed the acquisition of MiroBio, a biotechnology company specializing in immunotherapies, to strengthen its pipeline for liver cancer treatments.
    • Q1 2025: Sirnaomics Announces IND Clearance from FDA for STP707 in Advanced Liver Cancer Sirnaomics received Investigational New Drug (IND) clearance from the FDA to initiate clinical trials of STP707, a novel RNAi therapeutic, in patients with advanced liver cancer.
    • Q2 2025: Cure Genetics Raises $50 Million Series B to Advance Gene Therapy for Liver Cancer Cure Genetics raised $50 million in a Series B financing round to accelerate the development of its gene therapy platform targeting liver cancer.

    Future Outlook

    Liver Cancer Market Future Outlook

    The Liver Cancer Market is projected to grow at a 6.91% CAGR from 2024 to 2035, driven by advancements in treatment options, increasing prevalence, and enhanced diagnostic technologies.

    New opportunities lie in:

    • Development of personalized immunotherapy treatments for liver cancer patients.
    • Expansion of telehealth services for remote patient monitoring and consultations.
    • Investment in AI-driven diagnostic tools to improve early detection rates.

    By 2035, the Liver Cancer Market is expected to achieve substantial growth, reflecting evolving treatment paradigms and increased patient access.

    Market Segmentation

    Liver Cancer Market Treatment Type Outlook

    • Surgery
    • Radiation Therapy
    • Chemotherapy
    • Targeted Therapy
    • Immunotherapy

    Liver Cancer Market Type of Liver Cancer Outlook

    • Hepatocellular Carcinoma
    • Intrahepatic Cholangiocarcinoma
    • Fibrolamellar Carcinoma
    • Hepatoblastoma

    Liver Cancer Market Stage of Liver Cancer Outlook

    • Early Stage
    • Intermediate Stage
    • Advanced Stage

    Report Scope

    MARKET SIZE 20241.943(USD Billion)
    MARKET SIZE 20252.077(USD Billion)
    MARKET SIZE 20354.053(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)6.91% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesAdvancements in targeted therapies and immunotherapies are reshaping the Liver Cancer Market landscape.
    Key Market DynamicsRising demand for targeted therapies drives innovation and competition in the liver cancer treatment landscape.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

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    FAQs

    What is the current valuation of the Liver Cancer Market as of 2024?

    <p>The Liver Cancer Market was valued at 1.943 USD Billion in 2024.</p>

    What is the projected market valuation for the Liver Cancer Market in 2035?

    <p>The market is projected to reach 4.053 USD Billion by 2035.</p>

    What is the expected CAGR for the Liver Cancer Market during the forecast period 2025 - 2035?

    <p>The expected CAGR for the Liver Cancer Market during 2025 - 2035 is 6.91%.</p>

    Which companies are considered key players in the Liver Cancer Market?

    <p>Key players include Bristol-Myers Squibb, Roche, Merck & Co., AstraZeneca, Gilead Sciences, Novartis, Eli Lilly and Company, Amgen, and Bayer.</p>

    How does the market segment by the stage of liver cancer perform?

    <p>In 2024, the market segments by stage showed valuations of 0.583 USD Billion for Early Stage, 0.778 USD Billion for Intermediate Stage, and 0.582 USD Billion for Advanced Stage.</p>

    What are the treatment types contributing to the Liver Cancer Market?

    <p>Treatment types include Surgery at 0.583 USD Billion, Radiation Therapy at 0.387 USD Billion, Chemotherapy at 0.387 USD Billion, Targeted Therapy at 0.387 USD Billion, and Immunotherapy at 0.387 USD Billion in 2024.</p>

    What types of liver cancer are included in the market analysis?

    <p>The market analysis includes Hepatocellular Carcinoma valued at 1.0 USD Billion, Intrahepatic Cholangiocarcinoma at 0.5 USD Billion, Fibrolamellar Carcinoma at 0.2 USD Billion, and Hepatoblastoma at 0.2 USD Billion in 2024.</p>

    What is the growth outlook for the Liver Cancer Market in the coming years?

    <p>The Liver Cancer Market is expected to grow significantly, reaching 4.053 USD Billion by 2035.</p>

    How do the valuations of different liver cancer types compare?

    <p>Hepatocellular Carcinoma leads with 1.0 USD Billion, while Intrahepatic Cholangiocarcinoma follows at 0.5 USD Billion, indicating varying market dynamics.</p>

    What implications do the market trends have for future investments in liver cancer treatments?

    <p>The projected growth and increasing valuations suggest that investments in liver cancer treatments may yield favorable returns during the forecast period.</p>

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