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India Transthyretin Amyloidosis Market

ID: MRFR/HC/54253-HCR
200 Pages
Rahul Gotadki
October 2025

India Transthyretin Amyloidosis Market Research Report By Disease (Transthyretin (TTR) Familial Amyloid Polyneuropathy), By Gender (Male, Female), By Treatment (Small Molecule Treatment) and By End-User (Ambulatory Surgical Center, Clinics) - Forecast to 2035

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India Transthyretin Amyloidosis Market Summary

As per MRFR analysis, the India transthyretin amyloidosis market size was estimated at $298.98 Million in 2024. The India transthyretin amyloidosis market is projected to grow from 318.95 $ Million in 2025 to 608.95 $ Million by 2035, exhibiting a compound annual growth rate (CAGR) of 6.68% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The India The market is poised for growth driven by increased awareness and innovative therapies.

  • Rising awareness and education about transthyretin amyloidosis is enhancing patient diagnosis and treatment options.
  • Innovative therapeutic developments are emerging, particularly in the largest segment of pharmaceutical treatments.
  • The evolving regulatory landscape is facilitating faster approvals for new therapies, contributing to market expansion.
  • Key market drivers include the increasing incidence of transthyretin amyloidosis and advancements in diagnostic technologies.

Market Size & Forecast

2024 Market Size 298.98 (USD Million)
2035 Market Size 608.95 (USD Million)

Major Players

Alnylam Pharmaceuticals (US), Pfizer (US), Bristol-Myers Squibb (US), Ionis Pharmaceuticals (US), Eisai Co., Ltd. (JP), Amgen Inc. (US), Teva Pharmaceutical Industries Ltd. (IL), Horizon Therapeutics (IE)

India Transthyretin Amyloidosis Market Trends

The The market is currently experiencing notable developments, particularly in the context of India. The increasing awareness of this rare disease among healthcare professionals and patients is fostering a more informed approach to diagnosis and treatment. This heightened awareness is likely to lead to earlier detection, which may improve patient outcomes. Furthermore, advancements in diagnostic technologies and therapeutic options are contributing to a more robust market landscape. The introduction of novel therapies, including gene silencing and stabilizing agents, appears to be reshaping treatment paradigms, offering hope to patients and healthcare providers alike. In addition, the regulatory environment in India is evolving, with authorities showing a commitment to facilitating access to innovative treatments. This shift may encourage pharmaceutical companies to invest in research and development, potentially leading to a wider array of treatment options for transthyretin amyloidosis. As the market continues to mature, collaboration between stakeholders, including government bodies, healthcare providers, and industry players, is essential for addressing the challenges associated with this condition. Overall, the transthyretin amyloidosis market is poised for growth, driven by increased awareness, technological advancements, and supportive regulatory frameworks.

Rising Awareness and Education

There is a growing emphasis on educating healthcare professionals and the public about transthyretin amyloidosis. This trend is likely to enhance early diagnosis and treatment, ultimately improving patient outcomes.

Innovative Therapeutic Developments

The introduction of new therapies, such as gene silencing and stabilizing agents, is transforming treatment options. These innovations may provide more effective management strategies for patients.

Evolving Regulatory Landscape

The regulatory framework in India is adapting to support the introduction of novel treatments. This evolution may encourage investment in research and development, leading to a broader range of therapeutic options.

India Transthyretin Amyloidosis Market Drivers

Government Initiatives and Support

Government initiatives and support play a pivotal role in shaping the transthyretin amyloidosis market. In India, various health policies aim to enhance the availability of rare disease treatments, including those for transthyretin amyloidosis. The government has been actively promoting research and development in the field of rare diseases, which could lead to the introduction of new therapies. Financial incentives, such as grants and subsidies for pharmaceutical companies, are also being implemented to encourage innovation. Furthermore, public health campaigns aimed at raising awareness about rare diseases are likely to increase patient engagement and drive demand for treatments. As these initiatives gain momentum, the transthyretin amyloidosis market is expected to benefit from increased funding and resources.

Growing Investment in Biotechnology

The growing investment in biotechnology is a significant driver for the transthyretin amyloidosis market. In India, the biotechnology sector has witnessed substantial growth, with investments reaching approximately $11 billion in recent years. This influx of capital is fostering innovation in drug development, particularly for rare diseases like transthyretin amyloidosis. Biotech firms are increasingly focusing on developing novel therapies, including gene therapies and monoclonal antibodies, which hold promise for treating this condition. As the industry continues to evolve, the transthyretin amyloidosis market is likely to benefit from the introduction of cutting-edge treatments that address unmet medical needs. The synergy between biotechnology advancements and the demand for effective therapies could lead to a robust market landscape.

Advancements in Diagnostic Technologies

Advancements in diagnostic technologies are significantly impacting the transthyretin amyloidosis market. Enhanced imaging techniques and biomarker identification have improved the accuracy and speed of diagnosis, allowing for earlier intervention. For instance, the introduction of non-invasive imaging modalities, such as cardiac MRI, has revolutionized the detection of transthyretin amyloidosis. This is particularly relevant in India, where timely diagnosis can lead to better patient outcomes. The market for diagnostic tools is projected to grow, with estimates indicating a compound annual growth rate (CAGR) of around 15% over the next five years. As healthcare providers increasingly adopt these advanced technologies, the transthyretin amyloidosis market is likely to expand, driven by the need for effective and efficient diagnostic solutions.

Rising Patient Advocacy and Support Groups

Rising patient advocacy and support groups are emerging as a vital driver for the transthyretin amyloidosis market. In India, organizations dedicated to raising awareness about rare diseases are gaining traction, providing essential resources and support for patients and their families. These groups play a crucial role in educating the public and healthcare professionals about transthyretin amyloidosis, thereby increasing diagnosis rates and treatment uptake. Furthermore, they often collaborate with pharmaceutical companies and healthcare providers to facilitate access to therapies. As these advocacy efforts continue to grow, they are likely to enhance the visibility of transthyretin amyloidosis, leading to increased demand for treatments and a more informed patient population. This dynamic could significantly influence the market landscape in the coming years.

Increasing Incidence of Transthyretin Amyloidosis

The rising incidence of transthyretin amyloidosis in India is a crucial driver for the transthyretin amyloidosis market. Recent studies indicate that the prevalence of this condition is increasing, with estimates suggesting that approximately 1 in 100,000 individuals may be affected. This growing patient population necessitates enhanced diagnostic and therapeutic options, thereby stimulating market growth. As awareness of the disease expands among healthcare professionals and the public, more patients are likely to seek medical attention, leading to increased demand for treatments. Furthermore, the aging population in India, which is more susceptible to amyloidosis, contributes to the rising incidence. Consequently, the transthyretin amyloidosis market is poised for growth as healthcare systems adapt to meet the needs of this expanding demographic.

Market Segment Insights

Transthyretin Amyloidosis Market Disease Insights

The India Transthyretin Amyloidosis Market, particularly within the Disease segment, reflects a growing awareness and need for treatment options pertaining to conditions like Transthyretin (TTR) Familial Amyloid Polyneuropathy. This specific condition is caused by the accumulation of transthyretin proteins, leading to significant neurological damage and various systemic issues. In India, the incidence of TTR Familial Amyloid Polyneuropathy is underscored by a need for precise diagnostic tools and effective therapeutic interventions. As healthcare infrastructure in India advances, there is a noticeable shift towards developing targeted treatments, which is supported by increasing research initiatives and healthcare investments.

This segment has gained importance not only because of the rising patient population but also due to the collaboration between pharmaceutical companies and research institutions that aim to enhance patient care. Moreover, the government policies promoting rare disease management have laid a foundation that promotes therapy accessibility, further driving growth in this segment. The rising prevalence of genetic disorders and a growing understanding of the role of TTR in amyloidosis have also highlighted the significance of effective management strategies.

Given the complexity of symptoms associated with TTR Familial Amyloid Polyneuropathy, early diagnosis, and intervention have become key focus areas for healthcare professionals, thereby positively influencing the India Transthyretin Amyloidosis Market dynamics. As awareness increases in both the medical community and among patients regarding the implications of this condition, it is anticipated that community outreach and education will further refine treatment paradigms, optimizing patient outcomes.

Thus, the Disease segment related to TTR Familial Amyloid Polyneuropathy is poised to play a central role in shaping the future of the India Transthyretin Amyloidosis Market ecosystem, guided by advancements in science and a commitment to improving healthcare standards across the sector.This continuous growth and nurturing of knowledge around TTR-related disorders reflect both the challenges and opportunities that lie ahead in the management of such complex diseases, reinforcing the need for a strategic approach to market segmentation and targeted therapeutics.

Source: Primary Research, Secondary Research, MRFR Database and Analyst Review

Transthyretin Amyloidosis Market Gender Insights

The India Transthyretin Amyloidosis Market shows distinctive gender-related patterns, highlighting important trends in the disease's prevalence and management. Males are often observed to have a higher incidence of transthyretin amyloidosis, leading to a notable market interest in male-oriented treatments and therapeutics. However, females also represent a significant portion of the patient population. They are increasingly being targeted for tailored therapies, driven by the growing recognition of their unique health profiles and needs regarding this condition.

This differentiation contributes to the overall market segmentation, which reflects varying treatment approaches and healthcare responses. The trends within the India Transthyretin Amyloidosis Market signify a shift towards more specific and inclusive healthcare solutions. The awareness campaigns and education initiatives aimed at both genders are expected to drive early diagnosis and improve patient outcomes. Additionally, advancements in research targeting gender-specific responses to therapies offer promising avenues for market growth as healthcare providers seek to optimize clinical management strategies for both males and females, ensuring that both groups receive the necessary attention in their treatment paradigms.

Transthyretin Amyloidosis Market Treatment Insights

The Treatment segment of the India Transthyretin Amyloidosis Market focuses on various therapeutic approaches aimed at managing this condition effectively. Among these approaches, Small Molecule Treatment has gained prominence due to its targeted mechanism of action and ability to penetrate cellular membranes, thereby addressing the underlying pathology of transthyretin amyloidosis. This method often offers a favorable safety profile and is associated with improved patient compliance compared to traditional biologics. As awareness around transthyretin amyloidosis increases in India, driven by educational initiatives and advancements in diagnostic techniques, the demand for effective treatments is also expected to rise.

The Indian healthcare ecosystem, supported by government efforts to enhance access to innovative therapies, is paving the way for the introduction of Small Molecule Treatments, which are anticipated to become a significant component of the therapeutic landscape. The increasing focus on precision medicine further underscores the importance of such treatments, as they provide tailored options for patients based on their unique genetic and clinical profiles. Overall, Small Molecule Treatment is positioned to play a critical role in the ongoing evolution of the India Transthyretin Amyloidosis Market, addressing unmet needs and contributing to improved health outcomes.

Transthyretin Amyloidosis Market End-User Insights

The India Transthyretin Amyloidosis Market, under the End-User segmentation, reflects strong demand in various healthcare settings, particularly within Ambulatory Surgical Centers and Clinics. These healthcare environments are pivotal as they facilitate early diagnosis and treatment for patients suffering from transthyretin amyloidosis, thereby improving patient outcomes. Ambulatory Surgical Centers play a vital role in providing specialized, outpatient surgical care with enhanced efficiency, catering to the increasing patient population. Similarly, Clinics offer accessible healthcare options, emphasizing the importance of early intervention and ongoing management of the disease.

The rise in awareness about transthyretin amyloidosis among healthcare professionals and patients is essential, leading to a growing preference for treatment options available in these facilities. As advancements in diagnostics and therapeutic strategies continue to evolve, the role of these End-User categories becomes increasingly significant in the overall landscape of the India Transthyretin Amyloidosis Market, illustrating their critical contribution to disease management and patient care.

Get more detailed insights about India Transthyretin Amyloidosis Market

Key Players and Competitive Insights

The transthyretin amyloidosis market is characterized by a dynamic competitive landscape, driven by increasing awareness and advancements in treatment options. Key players such as Alnylam Pharmaceuticals (US), Pfizer (US), and Bristol-Myers Squibb (US) are at the forefront, each adopting distinct strategies to enhance their market presence. Alnylam Pharmaceuticals (US) focuses on innovation through its RNA interference technology, which has shown promise in treating hereditary transthyretin amyloidosis. Meanwhile, Pfizer (US) emphasizes strategic partnerships to bolster its research capabilities and expand its therapeutic portfolio. Bristol-Myers Squibb (US) is actively pursuing mergers and acquisitions to enhance its pipeline, indicating a robust approach to growth in this niche market. Collectively, these strategies contribute to a competitive environment that is increasingly focused on innovation and collaboration.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The market structure appears moderately fragmented, with several players vying for dominance. However, the collective influence of major companies is significant, as they leverage their resources and expertise to shape market dynamics. This competitive structure fosters an environment where innovation is paramount, and companies are incentivized to differentiate themselves through unique offerings.

In October 2025, Alnylam Pharmaceuticals (US) announced a collaboration with a leading Indian biotechnology firm to enhance local clinical trials for its therapies. This strategic move is likely to accelerate the development of treatments tailored to the Indian population, thereby expanding Alnylam's footprint in the region. Such collaborations may also facilitate regulatory approvals, enhancing market access for innovative therapies.

In September 2025, Pfizer (US) launched a new initiative aimed at increasing awareness and education about transthyretin amyloidosis among healthcare professionals in India. This initiative underscores Pfizer's commitment to addressing unmet medical needs and positions the company as a thought leader in the space. By fostering education, Pfizer may enhance its market share and drive demand for its therapies.

In August 2025, Bristol-Myers Squibb (US) completed the acquisition of a smaller biotech firm specializing in novel therapies for amyloidosis. This acquisition is indicative of Bristol-Myers Squibb's aggressive strategy to bolster its pipeline and diversify its offerings. The integration of innovative technologies from the acquired firm could potentially lead to the development of groundbreaking treatments, further solidifying Bristol-Myers Squibb's position in the market.

As of November 2025, current trends in the transthyretin amyloidosis market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are increasingly shaping the competitive landscape, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is likely to evolve, with a shift from price-based competition to a focus on technological advancements and supply chain reliability. This transition may ultimately enhance patient outcomes and foster a more sustainable market environment.

Key Companies in the India Transthyretin Amyloidosis Market market include

Industry Developments

In recent developments within the India Transthyretin Amyloidosis Market, innovative therapies and increased awareness have begun to enhance patient outcomes significantly. Companies such as Pfizer and Alnylam Pharmaceuticals have made notable advancements in their therapeutic offerings, contributing to the growth of this specialized market segment. In November 2022, Eisai announced collaborations to enhance their treatment protocols, further establishing their presence in India. The market is also witnessing growth in valuation as healthcare infrastructure improves, signaling a rising demand for efficient diagnosis and treatment of transthyretin amyloidosis, particularly among older populations in the country.

Additionally, there is reported interest in local partnerships by multinational corporations like Roche and Novartis to cultivate Research and Development initiatives aimed at localizing therapies, ensuring they cater effectively to the Indian demographic. While there haven't been publicly acknowledged mergers or acquisitions affecting the market in the past few months, the push for partnerships remains a vital theme as companies seek to expand their footprint in India. Overall, the progression in therapeutics and rising investments in healthcare infrastructure are shaping a promising future for transthyretin amyloidosis treatment in India.

Future Outlook

India Transthyretin Amyloidosis Market Future Outlook

The transthyretin amyloidosis market is projected to grow at a 6.68% CAGR from 2024 to 2035, driven by increasing awareness, advancements in diagnostics, and innovative therapies.

New opportunities lie in:

  • Development of targeted gene therapies for transthyretin amyloidosis
  • Expansion of telehealth services for remote patient monitoring
  • Investment in AI-driven diagnostic tools for early detection

By 2035, the market is expected to achieve substantial growth, driven by innovation and strategic investments.

Market Segmentation

India Transthyretin Amyloidosis Market Drug Outlook

  • Inotersen
  • Partisiran
  • Tafamidis
  • Others

India Transthyretin Amyloidosis Market Treatment Outlook

  • Small molecule treatment
  • Tafamidis
  • Diflunisal
  • RNAi Therapy
  • Organ Transplantation

India Transthyretin Amyloidosis Market Indication Outlook

  • Wild type ATTR Amyloidosis
  • Hereditary ATTR Amyloidosis

India Transthyretin Amyloidosis Market Distribution Channel Outlook

  • Retail pharmacy
  • Hospital pharmacy
  • Online pharmacy

Report Scope

MARKET SIZE 2024298.98(USD Million)
MARKET SIZE 2025318.95(USD Million)
MARKET SIZE 2035608.95(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)6.68% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Alnylam Pharmaceuticals (US)", "Pfizer (US)", "Bristol-Myers Squibb (US)", "Ionis Pharmaceuticals (US)", "Eisai Co., Ltd. (JP)", "Amgen Inc. (US)", "Teva Pharmaceutical Industries Ltd. (IL)", "Horizon Therapeutics (IE)"]
Segments CoveredDrug, Indication, Distribution Channel, Treatment
Key Market OpportunitiesAdvancements in gene therapies and novel therapeutics enhance treatment options in the transthyretin amyloidosis market.
Key Market DynamicsRising demand for innovative therapies drives competition in the transthyretin amyloidosis market.
Countries CoveredIndia

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FAQs

What is the projected market size of the India Transthyretin Amyloidosis Market in 2024?

The India Transthyretin Amyloidosis Market is expected to be valued at 365.0 million USD in 2024.

What will be the market valuation of the India Transthyretin Amyloidosis Market by 2035?

By 2035, the India Transthyretin Amyloidosis Market is projected to reach a valuation of 847.0 million USD.

What is the expected CAGR of the India Transthyretin Amyloidosis Market from 2025 to 2035?

The expected CAGR for the India Transthyretin Amyloidosis Market from 2025 to 2035 is 7.953%.

Which segment of the India Transthyretin Amyloidosis Market is expected to generate the highest revenue?

The Transthyretin (TTR) Familial Amyloid Polyneuropathy segment is expected to be valued at 300.0 million USD in 2024.

What will be the revenue of the Transthyretin (TTR) Familial Amyloid Polyneuropathy segment by 2035?

This segment is projected to grow to 700.0 million USD by the year 2035.

Who are the key players in the India Transthyretin Amyloidosis Market?

Major players in the market include Pfizer, Roche, Eisai, and Novartis among others.

What are the emerging trends in the India Transthyretin Amyloidosis Market?

Emerging trends include advancements in therapeutic options and increased awareness about Transthyretin Amyloidosis.

How will the overall growth of the Transthyretin Amyloidosis Market impact healthcare in India?

The growth of this market is expected to enhance treatment options and improve patient outcomes within the healthcare system.

What is the expected growth rate for specific segments in the India Transthyretin Amyloidosis Market?

The market segments are anticipated to grow in alignment with the overall CAGR of 7.953% from 2025 to 2035.

How does the India Transthyretin Amyloidosis Market compare regionally with other markets?

The India Transthyretin Amyloidosis Market is uniquely positioned due to its increasing patient base and expanding healthcare infrastructure.

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