Immortalized Cell Line Market Research Report - Global Forecast till 2027

Immortalized Cell Line Market Research Report: Information by Method (Virus Induction, HTERT Expression, Inactivation of Tumor Suppression Genes and others), Application (Diagnostics, Drug Discovery, Vaccine Production, Tissue Engineering and Regenerative Medicines and others), End User (Pharmaceutical and Biopharmaceutical Companies, Contract Research Organizations and Research Laboratories) and Region (Americas, Europe, Asia-Pacific and Middle East & Africa) - Forecast till 2027

ID: MRFR/LS/0267-CR | August 2019 | Region: Global | 130 pages

The Immortalized Cell Line Market is expected to register 9.30% CAGR and is anticipated to reach USD 4,105.62 Million by 2023. Immortalized cell lines are either tumorous cells that do not stop dividing or cells that have been artificially manipulated to proliferate indefinitely and can, thus, be cultured over several generations. These cell lines are expected to grow due to the rise in vaccine production and innovative technologies.

Besides, the ability of cell line culture to provide more physiologically relevant information and more accurate data in-vitro tests has led cell line culture systems to become acceptable in comparison to media culture.

The increasing application in biotech and pharmaceutical companies and hospitals, a growing number of patients in need of organ transplantation, and the rise in the patient population affected by cancer are the major drivers propelling market growth. However, the high cost of equipment and developing a stable strain of cell line and maintaining and preventing it from contamination may hinder the growth of the market.

Market Dynamics

The increasing demand for organ donation due to scarcity in the availability of organs is driving the need for artificially created biological cells. For instance, according to the US Department of Health & Human Services Organ Procurement and Transplantation Network (OPTN), as of November 2016, 121,678 patients were waiting for a life-saving organ transplant. This rising demand for an organ transplant is expected to drive the growth of the market during the forecast period. Additionally, increasing application in biotech and pharmaceutical companies and hospitals and rise in the patient population affected by cancer are likely to support market growth. On the other hand, the high cost of equipment and developing a stable strain of cell line and maintaining and preventing it from contamination is anticipated to hamper the market growth.

Immortalized Cell Line Market Size, by End User, 2017 (USD Million)

Source: MRFR Analysis

Segmentation

The immortalized cell line market has been segmented into method, application, and end user.

Based on the method, the global market has been segmented into virus induction, hTERT expression, inactivation of tumor suppression genes, and others. The virus induction segment is further divided into EBV genes, SV40 T antigen, HPV-16 E6/6 gene, and others. The hTERT expression segment is sub-segmented into P53 and Myc T58A.

The immortalized cell line market, based on application, is segmented into diagnostics, drug discovery, vaccine production, tissue engineering and regenerative medicine, and others.

Based on end user, the global market is segmented into pharmaceutical and biopharmaceutical companies, Contract Research Organizations (CROs), and research laboratories. The pharmaceutical and biopharmaceutical companies segment accounted for a market value of USD 1,323.79 million in 2017.

Key Players

The prominent players in the immortalized cell line market are Thermo Fisher Scientific (US), ATCC (American Type Culture Collection Inc.) (US), Valneva (France), Sartorius AG (Germany), Lonza Group, AG (Switzerland), Merck KGaA (Germany), Selexis SA (Switzerland), WuXi App Tec (China), European Collection of Authenticated Cell Cultures (ECACC) (Europe), and Corning Incorporated (US)

Some of the key strategies followed by the players operating in the immortalized cell line market are innovation, product development, acquisition, and expansion.

Immortalized Cell Line Market Share, by Region, 2017 (%)

Source: MRFR Analysis

Regional Analysis

The immortalized cell line market, based on region, is segmented into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.

The Americas is estimated to dominate the immortalized cell line market during the forecast period. This is attributed to an increase in the occurrence of cancer, the presence of well-established pharmaceutical and biotechnology industry, increasing awareness of immortalized cell lines, and strong research funding.

The European market for immortalized cell line is expected to be the second-largest during the forecast period. Increasing government support, well-developed technology, and rising cases of cancer are expected to boost the growth of the market in this region.

Asia-Pacific is estimated to be the fastest-growing market due to the increasing expenditure on healthcare by government and private sector companies. Moreover, the growing awareness about healthcare and large untapped patient population have led to the increased focus of key players on expansion in this region. Furthermore, the region accounted for a market share of 17.8% in 2017.

The immortalized cell line market in the Middle East & Africa is expected to hold the least market share.

Key Updates

In April 2018, Lonza Group, AG announced the opening of the world’s largest dedicated cell-and-gene-therapy manufacturing facility in Pearland, Greater Houston, TX (US). The manufacturing site was built in anticipation of the rising demand from developers of cell and gene therapies.

In August 2017, Thermo Fisher Scientific acquired Patheon for 7.2 USD million. Patheon’s CDMO services are likely to complement Thermo Fisher Scientific’s life sciences technologies designed to support research, clinical trials, and production.

Market Segmentation

Immortalized Cell Line Market, by Method

Virus Induction

EBV genes

SV40 T antigen

HPV-16 E6/6 gene

Others

HTERT Expression

Myc T58A

Inactivation of Tumour Suppression Genes

Others

Immortalized Cell Line Market, by Application

Diagnostics

Drug Discovery

Vaccine Production

Tissue Engineering and Regenerative Medicines

Others

Immortalized Cell Line Market, by End User

Pharmaceutical and Biopharmaceutical Companies

Contract Research Organizations

Research Laboratories

Immortalized Cell Line Market, by Region

Americas

North America

Canada

South America

Europe

Western Europe

Germany

France

Italy

Spain

Rest of Western Europe

Eastern Europe

Asia-Pacific

China

Japan

India

South Korea

Rest of Asia-Pacific

Middle East & Africa

Middle East

Africa

Intended Audience

Research and development (R&D) companies

Government research institutes

Academic institutes and universities

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Frequently Asked Questions (FAQ) :

What will be the value of the Immortalized Cell Line Market during the forecast period?

Immortalized Cell Line Market is predicted to touch USD 4,105.62 million by 2023.

At what CAGR is the Immortalized Cell Line Market projected to grow during the forecast period?

Immortalized Cell Line Market is projected to grow at a 9.30% CAGR between 2020-2027.

Which region is projected to dominate the Immortalized Cell Line Market?

North America is projected to dominate the Immortalized Cell Line Market.

Which end user segment will dominate the Immortalized Cell Line Market?

Pharmaceutical & biopharmaceutical companies will dominate the Immortalized Cell Line Market.

What are the key factors boosting the Immortalized Cell Line Market growth?

Increasing prevalence of cancer, growing need for organ transplantation, and rising application in hospitals, pharmaceutical & biotech companies are boosting market growth.

1 Report Prologue

2 Executive Summary

3 Market Introduction

3.1 Scope of Study 19

3.2 Research Objective 19

3.3 List of Assumptions 19

3.4 Market Structure 20

4 Research Methodology

4.1 Research Process 22

4.2 Primary Research 23

4.3 Secondary Research 24

4.4 Market Size Estimation 25

4.5 Forecast Model 25

5 Market Dynamics

5.1 Introduction 27

5.2 Drivers 28

5.2.1 Increasing Application in Biotech & Pharmaceutical Companies and Hospitals 28

5.2.2 Growing Number of Patients in Need of Organ Transplantation 28

5.2.3 Rise in the Patient Population Affected by Cancer 29

5.3 Restraints 29

5.3.1 High Cost of Equipment 29

5.3.2 Developing Stable and Authentic Cell Lines 29

5.4 Opportunities 30

5.4.1 Entering Untapped Markets 30

5.4.2 Increasing Use of cell Line Culture in Cancer and Stem Cell Research 30

6 Market Factor Analysis

6.1 Porters Five Forces Analysis 32

6.1.1 Bargaining Power of Suppliers 32

6.1.2 Bargaining Power of Buyers 32

6.1.3 Threat of New Entrants 32

6.1.4 Threat of Substitutes 33

6.1.5 Intensity of Rivalry 33

6.2 Supply Chain Analysis 33

6.2.1 R&D 33

6.2.2 Manufacturing 33

6.2.3 Distribution & Sales 34

6.2.4 Post-Sales Monitoring 34

6.3 Investment Opportunities 34

6.4 Pricing Analysis 34

7 Immortalized Cell Line Market, by Method

7.1 Overview 36

7.1.1 Virus Induction 38

7.1.2 HTERT Expression 39

7.1.3 Inactivation of Tumour Suppression Genes 40

7.1.4 Others 40

8 Immortalized Cell Line Market, by Application

8.1 Overview 42

8.1.1 Diagnostics 43

8.1.2 Drug Discovery 43

8.1.3 Vaccine Production 44

8.1.4 Tissue Engineering and Regenerative Medicines 45

8.1.5 Others 45

9 Immortalized Cell Line Market, by End-user

9.1 Overview 47

9.1.1 Introduction 47

9.1.2 Pharmaceutical and Biopharmaceutical Companies 48

9.1.3 Contract Research Organizations 48

9.1.4 Research Laboratories 49

10 Global Immortalized Cell Line Market, By Region

10.1 Overview 51

10.2 Americas 52

Immortalized Cell Line Market, by Method