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    Hepatitis Therapeutic Market

    ID: MRFR/HC/27716-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Hepatitis Therapeutic Market Size, Growth Research Report By Treatment Line (1st Line Treatment, 2nd Line Treatment and Beyond), By Spectrum of Disease (Chronic Hepatitis, Decompensated Cirrhosis, Hepatocellular Carcinoma), By Subtypes of Hepatitis (Hepatitis B (HBV), Hepatitis C (HCV)), By Drug Class (Antivirals, Immunomodulators), By Route of Administration (Oral, Injectable) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Competitor Industry Analysis and Trends Forecast Till 2035

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    Hepatitis Therapeutic Market Summary

    The Global Hepatitis Therapeutic Market is projected to grow from 46.37 USD Billion in 2024 to 107.59 USD Billion by 2035.

    Key Market Trends & Highlights

    Hepatitis Therapeutic Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate of 7.95 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 107.6 USD Billion, indicating robust growth.
    • in 2024, the market is valued at 46.37 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of innovative treatment options due to increasing prevalence of hepatitis is a major market driver.

    Market Size & Forecast

    2024 Market Size 46.37 (USD Billion)
    2035 Market Size 107.59 (USD Billion)
    CAGR (2025-2035) 7.95%

    Major Players

    Gilead Sciences, Merck Co., AbbVie, GlaxoSmithKline, AstraZeneca, Sanofi, Roche, Johnson Johnson, Vir Biotechnology, Novartis, Arbutus Biopharma, Allergan, Shionogi Co., Pfizer, Bristol Myers Squibb

    Hepatitis Therapeutic Market Trends

    Recent trends in the Hepatitis Therapeutic Market reveal a growing focus on precision medicine and combination therapies. The advent of direct-acting antivirals (DAAs) has revolutionized the treatment of Hepatitis C, with cure rates surpassing 90%.

    Ongoing research aims to develop pan-genotypic therapies effective against all Hepatitis C genotypes. Furthermore, there is a significant unmet need for effective treatments for Hepatitis B, driving innovation in immunotherapies and epigenetic modulators.

    The market is also witnessing the rise of personalized medicine approaches, tailoring treatments to individual patient profiles and disease characteristics.

    The ongoing advancements in antiviral therapies and the increasing awareness of hepatitis prevention strategies are likely to drive a transformative shift in the global hepatitis therapeutic landscape.

    Centers for Disease Control and Prevention (CDC)

    Hepatitis Therapeutic Market Drivers

    Rising Prevalence of Hepatitis

    The increasing incidence of hepatitis globally is a primary driver for the Global Hepatitis Therapeutic Market Industry. According to the World Health Organization, approximately 325 million people are living with hepatitis B and C worldwide. This growing patient population necessitates the development and availability of effective therapeutic options. As awareness of hepatitis-related complications rises, healthcare systems are prioritizing hepatitis treatment, contributing to market growth. The Global Hepatitis Therapeutic Market is projected to reach 46.4 USD Billion in 2024, reflecting the urgent need for innovative therapies to manage this widespread health issue.

    Growing Awareness and Education

    Enhanced awareness and education regarding hepatitis are crucial drivers for the Global Hepatitis Therapeutic Market Industry. Public health campaigns and educational programs are increasingly informing populations about the risks and consequences of hepatitis infections. Organizations such as the World Health Organization are actively promoting awareness initiatives that encourage screening and vaccination. This heightened awareness leads to earlier diagnosis and treatment, which is essential for effective management of the disease. As more individuals seek treatment, the demand for hepatitis therapeutics is expected to rise, further propelling market growth in the coming years.

    Government Initiatives and Funding

    Government initiatives aimed at combating hepatitis are pivotal to the Global Hepatitis Therapeutic Market Industry. Many countries are implementing national hepatitis strategies that include increased funding for research, public health campaigns, and access to treatment. For instance, the U.S. Centers for Disease Control and Prevention has launched initiatives to increase hepatitis screening and treatment accessibility. Such efforts not only raise awareness but also facilitate early diagnosis and treatment, thereby expanding the patient base for therapeutic products. This supportive environment is likely to contribute to a compound annual growth rate of 7.95 percent from 2025 to 2035 in the market.

    Advancements in Treatment Modalities

    Innovations in hepatitis treatment are significantly influencing the Global Hepatitis Therapeutic Market Industry. The introduction of direct-acting antivirals (DAAs) has revolutionized the management of hepatitis C, offering cure rates exceeding 95 percent. These advancements not only enhance patient outcomes but also reduce the long-term burden on healthcare systems. Furthermore, ongoing research into combination therapies and personalized medicine is expected to expand treatment options for hepatitis B and C. As a result, the market is anticipated to grow, with projections indicating a rise to 107.6 USD Billion by 2035, driven by these therapeutic advancements.

    Emerging Markets and Economic Growth

    The expansion of emerging markets is a significant factor influencing the Global Hepatitis Therapeutic Market Industry. Countries in regions such as Asia-Pacific and Latin America are experiencing economic growth, leading to improved healthcare infrastructure and increased access to medical treatments. As these economies develop, there is a growing demand for effective hepatitis therapies. This trend is particularly evident in nations with high hepatitis prevalence, where healthcare systems are prioritizing the treatment of viral hepatitis. Consequently, the market is poised for substantial growth, with emerging markets playing a critical role in shaping future therapeutic landscapes.

    Market Segment Insights

    Hepatitis Therapeutic Market Treatment Line Insights

    The Global Hepatitis Therapeutic Market is segmented into treatment lines, which includes 1st line treatment, 2nd line treatment and beyond. The 1st line treatment segment accounted for the largest share of the market in 2023 and is expected to continue to dominate the market over the forecast period.

    The growth of this segment can be attributed to the increasing prevalence of hepatitis B and C, as well as the availability of effective first-line treatment options. The market growth is attributed to the rising prevalence of hepatitis B and C, increasing awareness of the disease, and the availability of new and innovative treatment options.

    The market is also expected to benefit from the increasing government support for hepatitis B and C prevention and treatment programs.

    The high prevalence of hepatitis B and C in these regions is a major factor driving the growth of the market.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Hepatitis Therapeutic Market Spectrum of Disease Insights

    The Global Hepatitis Therapeutic Market is segmented based on the Spectrum of Disease into Chronic Hepatitis, Decompensated Cirrhosis, and Hepatocellular Carcinoma treatment. Chronic Hepatitis held the largest market share in 2023, owing to the high prevalence of chronic hepatitis B and C infections worldwide.

    The increasing incidence of cirrhosis and hepatocellular carcinoma is expected to drive the growth of the Decompensated Cirrhosis and Hepatocellular Carcinoma segments, respectively. The Global Hepatitis Therapeutic Market revenue for Chronic Hepatitis is projected to reach USD 24.71 billion by 2032, growing at a CAGR of 7.8%.

    The Decompensated Cirrhosis segment is expected to grow at a CAGR of 8.1%, reaching a market size of USD 10.03 billion by 2032. The Hepatocellular Carcinoma segment is expected to witness the fastest growth, with a CAGR of 8.3%, and is projected to reach a market size of USD 7.46 billion by 2032.

    Hepatitis Therapeutic Market Subtypes of Hepatitis Insights

    The Global Hepatitis Therapeutic Market is segmented into subtypes of Hepatitis, which include Hepatitis B (HBV) and Hepatitis C (HCV). The HBV segment accounted for a larger share of the market in 2023 and is expected to continue to dominate the market during the forecast period.

    The increasing prevalence of chronic HBV infection, coupled with the availability of effective antiviral therapies, is driving the growth of the HBV segment. The HCV segment is also expected to witness significant growth during the forecast period, owing to the increasing adoption of direct-acting antiviral (DAA) therapies.

    The DAA therapies offer high cure rates and have a shorter duration of treatment, which is contributing to the growth of the HCV segment.

    The Global Hepatitis Therapeutic Market is expected to witness robust growth over the forecast period, driven by the increasing prevalence of Hepatitis, the growing adoption of new and effective therapies, and the increasing healthcare expenditure in developing countries.

    Hepatitis Therapeutic Market Drug Class Insights

    The global Hepatitis Therapeutic Market is segmented by drug class into antivirals and immunomodulators. Antivirals are the most commonly used class of drugs for the treatment of hepatitis, and they work by inhibiting the replication of the hepatitis virus.

    Immunomodulators, on the other hand, work by modulating the immune system to help fight the infection. Antivirals accounted for the largest share of the global Hepatitis Therapeutic Market in 2023, and this trend is expected to continue in the coming years.

    The growth of the antivirals segment is being driven by the increasing prevalence of hepatitis C virus (HCV) infection, as well as the development of new and more effective antiviral drugs.

    Immunomodulators are expected to be the fastest-growing segment of the global Hepatitis Therapeutic Market over the forecast period. This growth is being driven by the increasing use of immunomodulators in the treatment of hepatitis B virus (HBV) infection, as well as the development of new and more effective immunomodulators.

    The Global Hepatitis Therapeutic Market is expected to grow from USD 39.79 billion in 2023 to USD 79.2 billion by 2032, at a CAGR of 7.95%.

    Hepatitis Therapeutic Market Route of Administration Insights

    The Global Hepatitis Therapeutic Market is segmented by Route of Administration into Oral and Injectable. The Oral segment held the largest market share in 2023 due to the ease of administration and patient preference for oral medications.

    The Injectable segment is expected to grow at a faster CAGR over the forecast period due to the increasing adoption of injectable therapies for the treatment of chronic hepatitis. In 2023, the Oral segment accounted for approximately 60% of the Global Hepatitis Therapeutic Market revenue, while the Injectable segment is expected to account for approximately 40%.

    By 2032, the Oral segment is expected to account for approximately 55% of the market revenue, while the Injectable segment is expected to account for approximately 45%.

    The growth of the Injectable segment is expected to be driven by the increasing adoption of long-acting injectable therapies, which offer sustained drug release and improved patient compliance. The development of new and more effective injectable therapies is also expected to contribute to the growth of this segment.

    Get more detailed insights about Hepatitis Therapeutic Market

    Regional Insights

    The regional segmentation of the Global Hepatitis Therapeutic Market presents distinct opportunities and challenges for market participants. North America holds a significant share of the market, driven by factors such as high healthcare expenditure, advanced healthcare infrastructure, and a large patient population with chronic hepatitis.

    The market in Europe is also well-established, with a focus on innovative therapies and precision medicine. The Asia-Pacific region is expected to witness substantial growth in the coming years, fueled by rising healthcare awareness, increasing prevalence of hepatitis, and government initiatives to improve healthcare access.

    South America and the Middle East and Africa (MEA) regions represent emerging markets with untapped potential, offering significant growth opportunities for market players. The market in these regions is expected to be driven by rising disposable income, expanding healthcare infrastructure, and increasing awareness about hepatitis.

    Hepatitis Therapeutic Market Regional

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    Major players in the Hepatitis Therapeutic Market industry are constantly striving to gain a competitive edge by investing in research and development, expanding their product portfolios, and forming strategic partnerships.

    Leading Hepatitis Therapeutic Market players are focusing on developing innovative therapies that target specific genotypes of the hepatitis virus and offer improved efficacy and safety profiles. The Hepatitis Therapeutic Market development landscape is characterized by a high level of collaboration between pharmaceutical companies, research institutions, and government agencies.

    Companies are actively involved in clinical trials to evaluate the safety and efficacy of new Hepatitis Therapeutic Market products. The competitive landscape is expected to remain dynamic, with new entrants and mergers and acquisitions shaping the market dynamics.

    One of the leading Hepatitis Therapeutic Market players, Gilead Sciences, has established a strong position in the market with its blockbuster drug, Sovaldi. Sovaldi is a directly acting antiviral that has revolutionized the treatment of hepatitis C.

    Gilead Sciences is continuing to invest in research and development to maintain its leadership position. Another major player in the Hepatitis Therapeutic Market is Merck Co., which has a diverse portfolio of hepatitis drugs, including Zepatier and Harvoni. Merck Co. is focusing on developing new therapies for hepatitis B and hepatitis D.

    AbbVie is a rapidly growing Hepatitis Therapeutic Market player with a robust pipeline of new products. The company's lead product, Mavyret, is a combination therapy for hepatitis C that has demonstrated high efficacy rates.

    AbbVie is also developing treatments for hepatitis B and other liver diseases. These leading players are constantly striving to gain a competitive edge by investing in research and development, expanding their product portfolios, and forming strategic partnerships.

    Key Companies in the Hepatitis Therapeutic Market market include

    Industry Developments

    • Q2 2024: FDA approves Gilead’s Hepcludex for chronic hepatitis D in the United States Gilead Sciences received FDA approval for Hepcludex (bulevirtide), a new treatment for chronic hepatitis D, marking the first approved therapy for this rare and severe form of viral hepatitis in the U.S.
    • Q2 2024: Vir Biotechnology Announces Positive Phase 2 Data for VIR-2218 in Chronic Hepatitis B Vir Biotechnology reported positive results from its Phase 2 trial of VIR-2218, an investigational RNAi therapeutic for chronic hepatitis B, supporting further development and potential regulatory submission.
    • Q2 2024: Enanta Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial of EDP-938 for Hepatitis C Enanta Pharmaceuticals began a Phase 1 clinical trial for EDP-938, a novel antiviral candidate targeting hepatitis C, expanding its pipeline in hepatitis therapeutics.
    • Q3 2024: AbbVie and GenScript ProBio Announce Strategic Partnership to Develop Next-Generation Hepatitis B Therapies AbbVie and GenScript ProBio entered a strategic partnership to co-develop innovative therapies for chronic hepatitis B, aiming to advance new treatment modalities through joint research and development.
    • Q3 2024: FDA grants Fast Track designation to Assembly Biosciences’ ABI-H3733 for chronic hepatitis B Assembly Biosciences received Fast Track designation from the FDA for ABI-H3733, an investigational core inhibitor for chronic hepatitis B, expediting its clinical development and review process.
    • Q3 2024: Janssen Opens New Manufacturing Facility for Hepatitis Therapeutics in Ireland Janssen, a Johnson & Johnson company, inaugurated a new manufacturing facility in Ireland dedicated to producing hepatitis therapeutics, expanding its global supply capabilities.
    • Q4 2024: Aligos Therapeutics Announces $50 Million Series C Financing to Advance Hepatitis B Pipeline Aligos Therapeutics secured $50 million in Series C funding to support the development of its hepatitis B drug candidates, including advancing clinical trials and expanding research efforts.
    • Q4 2024: FDA Approves VBI Vaccines’ PreHevbri for Prevention of Hepatitis B in Adults VBI Vaccines received FDA approval for PreHevbri, a new hepatitis B vaccine for adults, expanding immunization options in the U.S. market.
    • Q1 2025: GSK acquires exclusive rights to Arrowhead’s ARO-HBV for $300 million upfront GSK acquired exclusive global rights to Arrowhead Pharmaceuticals’ ARO-HBV, an investigational RNAi therapeutic for chronic hepatitis B, with a $300 million upfront payment and potential milestone payments.
    • Q1 2025: FDA grants Breakthrough Therapy designation to Vir Biotechnology’s VIR-3434 for hepatitis B Vir Biotechnology received Breakthrough Therapy designation from the FDA for VIR-3434, an investigational monoclonal antibody for chronic hepatitis B, accelerating its clinical development.
    • Q2 2025: Eiger BioPharmaceuticals Announces European Commission Approval of Hepcludex for Hepatitis D Eiger BioPharmaceuticals received European Commission approval for Hepcludex (bulevirtide) for the treatment of hepatitis D, expanding its availability in the European market.
    • Q2 2025: FDA Approves Gilead’s Vemlidy for Pediatric Chronic Hepatitis B Gilead Sciences received FDA approval for Vemlidy (tenofovir alafenamide) for the treatment of chronic hepatitis B in pediatric patients, broadening its therapeutic indications.

    Future Outlook

    Hepatitis Therapeutic Market Future Outlook

    The Global Hepatitis Therapeutic Market is poised for growth at 7.95% CAGR from 2025 to 2035, driven by advancements in treatment options, increasing prevalence, and enhanced healthcare access.

    New opportunities lie in:

    • Develop novel antiviral therapies targeting resistant hepatitis strains.
    • Expand telehealth services for hepatitis management and patient education.
    • Invest in regional partnerships to enhance distribution networks in emerging markets.

    By 2035, the Hepatitis Therapeutic Market is expected to demonstrate robust growth, reflecting ongoing innovations and expanded treatment access.

    Market Segmentation

    Hepatitis Therapeutic Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Hepatitis Therapeutic Market Drug Class Outlook

    • Antivirals
    • Immunomodulators

    Hepatitis Therapeutic Market Treatment Line Outlook

    • 1st Line Treatment
    • 2nd Line Treatment and Beyond

    Hepatitis Therapeutic Market Spectrum of Disease Outlook

    • Chronic Hepatitis
    • Decompensated Cirrhosis
    • Hepatocellular Carcinoma

    Hepatitis Therapeutic Market Subtypes of Hepatitis Outlook

    • Hepatitis B (HBV)
    • Hepatitis C (HCV)

    Hepatitis Therapeutic Market Route of Administration Outlook

    • Oral
    • Injectable

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024   46.37 (USD Billion)
    Market Size 2025   50.06 (USD Billion)
    Market Size 2035 107.59 (USD Billion)
    Compound Annual Growth Rate (CAGR) 7.95% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled GlaxoSmithKline, AstraZeneca, Sanofi, Roche, Johnson Johnson, Merck Co., Vir Biotechnology, Novartis, Arbutus Biopharma, Allergan, Shionogi Co., Pfizer, Gilead Sciences, AbbVie, Bristol Myers Squibb
    Segments Covered Treatment Line, Spectrum of Disease, Subtypes of Hepatitis, Drug Class, Route of Administration, Regional
    Key Market Opportunities Growing prevalence of hepatitis Advancements in drug discovery Emerging markets Orphan drug designation Government initiatives
    Key Market Dynamics Increasing prevalence of hepatitis Advancements in treatment options Growing government initiatives Favorable reimbursement policies Rising awareness of hepatitis
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the projected growth of the Hepatitis Therapeutic market?

    The Hepatitis Therapeutic market is the expected increase in total market value of 107.59 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Hepatitis Therapeutic market?

    Hepatitis Therapeutic market size was valued at approximately 46.37 billion USD in 2024. This figure will reach 107.59 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Hepatitis Therapeutic market?

    Hepatitis Therapeutic market is expected to grow at a CAGR of 7.95% between 2025 and 2035.

    How much will the Hepatitis Therapeutic market be worth by 2035?

    Hepatitis Therapeutic market is expected to be worth of 107.59 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Hepatitis Therapeutic market perform over the next 10 years?

    Over the next 10 years the Hepatitis Therapeutic market is expected to shift from usd billion 46.37 to 107.59 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region is expected to hold the largest market share in the Global Hepatitis Therapeutic Market?

    North America is expected to dominate the Global Hepatitis Therapeutic Market throughout the forecast period.

    What are the key factors driving the growth of the Global Hepatitis Therapeutic Market?

    The rising prevalence of hepatitis, increasing awareness, and technological advancements are major factors propelling the market growth.

    Who are some of the prominent players operating in the Global Hepatitis Therapeutic Market?

    Key players in the market include Gilead Sciences, Merck Co., Inc., Bristol-Myers Squibb, and AbbVie Inc.

    What was the market size of the Global Hepatitis Therapeutic Market in 2024?

    The Global Hepatitis Therapeutic Market was valued at approximately USD 39.79 billion in 2024.

    What are the major challenges faced by the Global Hepatitis Therapeutic Market?

    Patent expiries, stringent regulatory policies, and the emergence of biosimilars pose challenges to market growth.

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