Vanishing Bone Disease Market Research Report – Forecast to 2027

Vanishing Bone Disease Market Research Report: Diagnosis (X-Rays, CT Scans, MRIs, Ultrasound, Nuclear Medicine, Others), Treatment (Medicine Therapy, Radiation Therapy), End-User (Hospitals, Diagnostic Centers, Others) – Forecast Till 2027

ID: MRFR/MED/4689-HCR | February 2021 | Region: Global | 100 pages

Vanishing Bone Disease Market Scenario:


The vanishing bone disease market size is expected to gain prominence over the forecast period (2018–2023). It is estimated that the global vanishing bone disease industry is expected to register a CAGR ~6.1 % during the forecast period of 2018–2023.

Vanishing bone disease or Gorham-stout syndrome is a rare skeletal disease characterized by progressive osteolysis and the proliferation of lymphatic vessels within the bone which leads to the destruction and absorption of bone. Additionally, the bones affected by the disease are more prone to osteopenia and fracture. Furthermore, the exact cause of the disease is unknown. However, it is considered to be caused due to the improper development of the lymphatic system.

According to the National Center for Advancing Translational Sciences (NIH), in 2016, the number of cases of vanishing bone disease reported ranged from 64 to 200 cases globally. The growing occurrence of the disease is the key driver for the growth of the market. Furthermore, current research for the development of an effective therapeutic intervention for disease treatment is expected to contribute to the growth of the market.

However, lack of awareness of the disease in developing economies, high treatment cost restrains the market growth. Furthermore, challenges in diagnosis of the disease in the patient pool may hamper the growth of the market.

Segmentation

The global vanishing bone disease market is segmented on the basis of the diagnosis, treatment, and end-user.

On the basis of diagnosis, the market is classified as X-rays, CT scans, MRIs, ultrasound, nuclear medicine, and others.

On the basis of treatment, the market is segmented as medical therapy and radiation therapy. The medicine therapy is segmented into bisphosphonates, vitamin D, interferon, a-2b interferon, calcium, adrenal extracts, androgen, bleomycin, and others. The radiation therapy is further segmented into chest drainage, thoracic duct ligation, pleurodesis, pleurectomy, and others.

On the basis of end-user, the global market is segmented as hospitals & clinics, diagnostic centers, ambulatory surgical centers, and others.

Geographically, the market has been segmented into America, Europe, Asia Pacific, and the Middle East and Africa. The American market is further segmented into North America and South America. North America is further classified as the U.S. and Canada.

The European market is segmented into Western Europe and Eastern Europe. Western Europe is further classified as Germany, France, the U.K., Italy, Spain, and the rest of Western Europe.

The Asia Pacific market is segmented into Japan, China, India, Republic of Korea, Australia, and the rest of Asia Pacific.

The Middle Eastern and African market is segmented into the Middle East and Africa.

Regional Market Summary

Global Vanishing Bone Disease Market, by Region Market Share, 2017 (%)

 Vanishing Bone Disease Market

Source: MRFR Analysis

The global vanishing bone disease market consists of four regions: Americas, Europe, Asia Pacific and the Middle East & Africa. The North American region dominates the global vanishing bone market due to the existing well-established healthcare system, increasing occurrences of rare diseases. For instance, according to the National Institute of Health, rare disorders that affect approximately 30 million people in the United States.  Furthermore, according to the U.S. FDA, rare diseases or disorder affects an approximate 200,000 people in the United States.

Europe holds the second market share in the vanishing bone disease market. It is expected that the government support towards research & development expenditure and rising incidences of rare diseases is likely to drive the European market. For instance, according to the European Commission, rare diseases comprises 5000 to 8000 life-threatening or chronically debilitating diseases which together affect from 27 and 36 million people in the European Union.

The Asia Pacific, vanishing bone disease market, consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia Pacific. The vanishing bone disease market growth in this region is driven by rising healthcare expenditure, rising occurrences of rare diseases, and growing bone disorders, technological advancements in interventional radiology segment. For instance, in February 2018, Elekta AB received clearance from China Food and Drug Administration (CFDA) for its Leksell Gamma Knife Icon radiosurgery system.

The Middle East & Africa holds the lowest share of the global vanishing bone disease market due to lack of awareness of rare diseases, the low incidence rate of the disease and poor medical facilities, especially in the African region.

Key Players


  • Varian Medical Systems, Inc

  • Elekta AB

  • C. R. Bard, Inc

  • Teleflex Incorporated

  • Vygon S.A

  • Medtronic plc

  • Cook Medical

  • Smiths Medical

  • ATMOS MedizinTechnik GmbH & Co. KG

  • Merck & Co

  • Sanofi-Aventis

  • F. Hoffmann-La Roche AG

  • Novartis International AG 


Research Methodology

Market Research Future research is conducted by industry experts who offer insight into industry structure, market segmentation, Treatment assessment, competitive landscape (CL), penetration, as well as on emerging trends. Besides primary interviews (~ 80%) and secondary research (~ 20%), their analysis is based on their years of professional expertise in respective industries. Our analysts also predict where the market will be headed in the next five to ten years, by analyzing historical trends and current market positions. Furthermore, the varying trends of segments & categories geographically presented are studied and are estimated based on primary & secondary research.


  • Primary Research


Extensive primary research was conducted to gain a deeper insight into the market and the industry performance. In this particular report, we have conducted primary surveys (interviews) with the key level executives (VPs, CEOs, Marketing Directors, Business Development Managers, and many more) of the major players who are active in the market. In addition to analyzing the current and historical trends, our analysts predict where the market is headed, over the next five to ten years.



  • Secondary Research


Secondary research was mainly used to collect and identify information useful for an extensive, technical, market-oriented, and commercial study of the vanishing bone disease market. It was also used to obtain key information about major players, market classification and segmentation according to the industry trends, geographical markets, & developments related to the market and Treatment Perspectives. For this study, analysts have gathered information from various credible sources, such as annual reports, SEC filings, journals, white papers, corporate presentations, company websites, the international organization of chemical manufacturers, some paid databases and many others.


Global Vanishing Bone Disease Market, by Diagnosis



  • X-rays

  • CT Scans

  • MRIs

  • Ultrasound

  • Nuclear Medicine

  • Others


Global Vanishing Bone Disease Market, by Treatment



  • Medicine Therapy

  • Bisphosphonates

  • Vitamin D

  • Interferon

  • a-2b Interferon

  • Calcium

  • Adrenal extracts

  • Androgens

  • Bleomycin

  • Others

  • Radiation Therapy

  • Chest drainage

  • Thoracic Duct Ligation

  • Pleurodesis

  • Pleurectomy

  • Others


Global Vanishing Bone Disease Market, by End-User



  • Hospitals and clinics

  • Diagnostic centers

  • Ambulatory surgical centers


Global Vanishing Bone Disease Market, by Region



  • Americas

  • North America

  • U.S.

  • Canada

  • South America

  • Europe

  • Western Europe

  • Germany

  • France

  • Italy

  • Spain

  • U.K.

  • Rest of Western Europe

  • Eastern Europe

  • Asia Pacific

  • Japan

  • China

  • India

  • Australia

  • Republic of Korea

  • Rest of Asia Pacific

  • The Middle East & Africa

  • Middle East

  • Africa


Intended Audience



  • Pharmaceutical Companies

  • Research and Development (R&D) Companies

  • Government Research Institutes



Report Scope:
Report Attribute/Metric Details
  Market Size   Significant Value
  CAGR   2018-2023: ~6.1%
  Base Year   2019
  Forecast Period   2027
  Historical Data   2018
  Forecast Units   Value (USD Million)
  Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
  Segments Covered   Diagnosis, Treatment, and End-user
  Geographies Covered   North America, Europe, Asia-Pacific, and Rest of the World (RoW)
  Key Vendors   Varian Medical Systems, Inc., Elekta AB, C. R. Bard, Inc., Teleflex Incorporated, Vygon S.A. Medtronic plc., Cook Medical, Smiths Medical, ATMOS MedizinTechnik GmbH & Co. KG, Merck & Co., Sanofi-Aventis, F. Hoffmann-La Roche AG, and Novartis International AG
  Key Market Opportunities   Research for the development of the effective therapeutic intervention for the disease treatment
  Key Market Drivers

  • Number of cases of vanishing bone disease
  • Growing occurrence of the disease


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    Frequently Asked Questions (FAQ) :


    VANISHING BONE DISEASE or Gorham-stout syndrome is a rare skeletal disease characterized by progressive osteolysis and proliferation of lymphatic vessels within the bone, which leads to the destruction and absorption of bone.

    Global Vanishing Bone Disease Market is expected to exhibit a strong 6.1% CAGR over the forecast period from 2018 to 2023.

    The growing prevalence of vanishing bone disease is the major driver for the market.

    North America dominates the Global Vanishing Bone Disease Market.

    Leading players in the Vanishing Bone Disease Market include Elekta AB, Varian Medical Systems, and Teleflex Inc., among others.

    Table of Contents:

    Chapter 1. Report Prologue

    Chapter 2. Market Introduction

    2.1 Definition

    2.2 Scope of the Study

    2.2.1 Research Objective

    2.2.2 Assumptions

    2.2.3 Limitations

    Chapter 3. Research Methodology

    3.1 Introduction

    3.2 Primary Research

    3.3 Secondary Research

    3.4 Market Size Estimation

    Chapter 4. Market Dynamics

    4.1 Drivers

    4.2 Restraints

    4.3 Opportunities

    4.4 Challenges

    4.5 Macroeconomic Indicators

    4.6 Technology Trends & Assessment

    Chapter 5. Market Factor Analysis

    5.1 Porter’s Five Forces Analysis

    5.1.1 Bargaining Power of Suppliers

    5.1.2 Bargaining Power of Buyers

    5.1.3 Threat of New Entrants

    5.1.4 Threat of Substitutes

    5.1.5 Intensity of Rivalry

    5.2 Value Chain Analysis

    5.3 Investment Feasibility Analysis

    5.4 Pricing Analysis

    Chapter 6. Global Vanishing Bone Disease Market, by Diagnosis

    6.1 Introduction

    6.2 X-ray

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    6.3 CT Scans

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    6.4 MRIs

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    6.5 Ultrasound

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    6.6 Nuclear Medicine

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    6.7 Others

    Chapter 7. Global Vanishing Bone Disease Market, by Treatment

    7.1 Introduction

    7.2 Medicine Therapy

    7.2.1 Bisphosphonates

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.2 Vitamin D

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.3 Interferon

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.4 a-2b Interferon

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.5 Calcium

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.6 Adrenal Extracts

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.7 Androgens

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.8 Bleomycin

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.2.9 Others

    7.3 Radiation Therapy

    7.3.1 Chest Drainage

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.3.2 Thoracic Duct Ligation

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.3.3 Pleurodesis

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.3.4 Pleurectomy

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    7.3.5 Others

    Chapter 8. Global Vanishing Bone Disease Market, by End-User

    8.1 Introduction

    8.2 Hospitals & clinics

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    8.3 Diagnostic Centers

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    8.4 Ambulatory Surgical Centers

    Market Estimates & Forecast, by Region, 2020-2027

    Market Estimates & Forecast, by Country, 2020-2027

    8.4 Others

    Chapter 9. Global Vanishing Bone Disease Market, by Region

    9.1 Introduction

    9.2 Americas

    9.2.1 North America

    9.2.1.1 U.S.

    9.2.1.2 Canada

    9.2.2 South America

    9.3 Europe

    9.3.1 Western Europe

    9.3.1.1 Germany

    9.3.1.2 France

    9.3.1.3 Italy

    9.3.1.4 Spain

    9.3.1.5 U.K.

    9.3.1.6 Rest of Western Europe

    9.3.2 Eastern Europe

    9.4 Asia Pacific

    9.4.1 Japan

    9.4.2 China

    9.4.3 India

    9.4.4 Australia

    9.4.5 Republic of Korea

    9.4.6 Rest of Asia Pacific

    9.5 The Middle East & Africa

    9.5.1 The Middle East

    9.5.2 Africa

    Chapter 10. Company Landscape

    10.1 Introduction

    10.2 Market Share Analysis

    10.3 Key Development & Strategies

    Chapter 11. Company Profiles

    11.1 Varian Medical Systems, Inc.

    11.1.1 Company Overview

    11.1.2 Product Overview

    11.1.3 Financials Overview

    11.1.4 Key Developments

    11.1.5 SWOT Analysis

    11.2 Elekta AB

    11.2.1 Company Overview

    11.2.2 Product Overview

    11.2.3 Financial Overview

    11.2.4 Key Developments

    11.2.5 SWOT Analysis

    11.3 C.R. Bard, Inc.

    11.3.1 Company Overview

    11.3.2 Product Overview

    11.3.3 Financial Overview

    11.3.4 Key Development

    11.3.5 SWOT Analysis

    11.4 Teleflex Incorporated

    11.4.1 Company Overview

    11.4.2 Technology/Business Segment Overview

    11.4.3 Financial Overview

    11.4.4 Key Development

    11.4.5 SWOT Analysis

    11.5 Vygon S.A.

    11.5.1 Company Overview

    11.5.2 Product Overview

    11.5.3 Financial overview

    11.5.4 Key Developments

    11.5.5 SWOT Analysis

    11.6 Medtronic Plc

    11.6.1 Company Overview

    11.6.2 Product Overview

    11.6.3 Financial Overview

    11.6.4 Key Developments

    11.6.5 SWOT Analysis

    11.7 Cook Medical

    11.7.1 Overview

    11.7.2 Product Overview

    11.7.3 Financial Overview

    11.7.4 Key Developments

    11.7.5 SWOT Analysis

    11.8 Smiths Medical

    11.8.1 Overview

    11.8.2 Product/ Technology Overview

    11.8.3 Financials

    11.8.4 Key Developments

    11.8.5 SWOT Analysis

    11.9 ATMOS Medizin Technik GmbH &b Co. KG

    11.9.1 Overview

    11.9.2 Product Overview

    11.9.3 Financials

    11.9.4 Key Developments

    11.9.5 SWOT Analysis

    11.10 Merck & Co.

    11.10.1 Overview

    11.10.2 Product Overview

    11.10.3 Financials

    11.10.4 Key Developments

    11.10.5 SWOT Analysis

    11.11 Sanofi-Aventis

    11.11.1 Overview

    11.11.2 Product Overview

    11.11.3 Financials

    11.11.4 Key Developments

    11.11.5 SWOT Analysis

    11.12 F. Hoffman-La Roche AG

    11.12.1 Overview

    11.12.2 Product Overview

    11.12.3 Financials

    11.12.4 Key Developments

    11.12.5 SWOT Analysis

    11.13 Novartis International AG

    11.13.1 Overview

    11.13.2 Product Overview

    11.13.3 Financials

    11.13.4 Key Developments

    11.13.5 SWOT Analysis

    Chapter 12 MRFR Conclusion

    12.1 Key Findings

    12.1.1 From CEO’s View Point

    12.1.2 Unmet Needs of the Market

    12.2 Key Companies to Watch

    12.3 Prediction of the Arthroscopy Instruments Industry

    Chapter 13 Appendix

    LIST OF TABLES

    Table 1 Global Vanishing Bone Disease Market Synopsis, 2020-2027

    Table 2 Global Vanishing Bone Disease Market Estimates and Forecast, 2020-2027, (USD Million)

    Table 3 Global Vanishing Bone Disease Market, by Region, 2020-2027, (USD Million)

    Table 4 Global Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 5 Global Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 6 Global Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 7 North America Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 8 North America Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 9 North America Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 10 U.S. Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 11 U.S. Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 12 U.S. Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 13 Canada Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 14 Canada Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 15 Canada Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 16 South America Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 17 South America Global Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 18 South America Global Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 19 Europe Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 20 Europe Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 21 Europe Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 22 Western Europe Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 23 Western Europe Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 24 Western Europe Global Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 25 Eastern Europe Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 26 Eastern Europe Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 27 Eastern Europe Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 28 Asia Pacific Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 29 Asia Pacific Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 30 Asia Pacific Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    Table 31 Middle East & Africa Vanishing Bone Disease Market, by Diagnosis, 2020-2027, (USD Million)

    Table 32 Middle East & Africa Vanishing Bone Disease Market, by Treatment, 2020-2027, (USD Million)

    Table 33 Middle East & Africa Vanishing Bone Disease Market, by End-User, 2020-2027, (USD Million)

    LIST OF FIGURES

    Figure 1 Research Process

    Figure 2 Segmentation for Global Vanishing Bone Disease Market

    Figure 3 Segmentation Market Dynamics for Global Vanishing Bone Disease Market

    Figure 4 Global Vanishing Bone Disease Market Share, by Diagnosis, 2020

    Figure 5 Global Vanishing Bone Disease Market Share, by Treatment, 2020

    Figure 6 Global Vanishing Bone Disease Market Share, by Region, 2020

    Figure 7 North America Vanishing Bone Disease Market Share, by Country, 2020

    Figure 8 Europe Vanishing Bone Disease Market Share, by Country, 2020

    Figure 9 Asia Pacific Vanishing Bone Disease Market Share, by Country, 2020

    Figure 10 Middle East & Africa Vanishing Bone Disease Market Share, by Country, 2020

    Figure 11 Global Vanishing Bone Disease Market: Company Share Analysis, 2020 (%)

    Figure 12 Varian Medical Systems, Inc.,: Key Financials

    Figure 13 Varian Medical Systems, Inc.,: Segmental Revenue

    Figure 14 Varian Medical Systems, Inc.,: Geographical Revenue

    Figure 15 Elekta AB: Key Financials

    Figure 16 Elekta AB: Segmental Revenue

    Figure 17 Elekta AB: Geographical Revenue

    Figure 18 C. R. Bard, Inc.: Key Financials

    Figure 19 C. R. Bard, Inc: Segmental Revenue

    Figure 20 C. R. Bard, Inc: Geographical Revenue

    Figure 21 Teleflex Incorporated: Key Financials

    Figure 22 Teleflex Incorporated: Segmental Revenue

    Figure 23 Teleflex Incorporated: Geographical Revenue

    Figure 24 Vygon S.A.: Key Financials

    Figure 25 Vygon S.A: Segmental Revenue

    Figure 26 Vygon S.A: Geographical Revenue

    Figure 27 Medtronic Plc: Key Financials

    Figure 28 Medtronic Plc: Segmental Revenue

    Figure 29 Medtronic Plc: Geographical Revenue

    Figure 30 Cook Medical: Key Financials

    Figure 31 Cook Medical: Segmental Revenue

    Figure 32 Cook Medical: Geographical Revenue

    Figure 33 Smiths Medical: Key Financials

    Figure 34 Smiths Medical: Segmental Revenue

    Figure 35 Smiths Medical: Geographical Revenue

    Figure 36 ATMOS MedizinTechnik GmbH & Co. KG: Key Financials

    Figure 37 ATMOS MedizinTechnik GmbH & Co. KG: Segmental Revenue

    Figure 38 ATMOS MedizinTechnik GmbH & Co. KG: Geographical Revenue

    Figure 39 Merck & Co.: Key Financials

    Figure 40 Merck & Co.: Segmental Revenue

    Figure 41 Merck & Co.: Geographical Revenue

    Figure 42 Sanofi-Aventis: Key Financials

    Figure 43 Sanofi-Aventis: Segmental Revenue

    Figure 44 Sanofi-Aventis: Geographical Revenue

    Figure 45 F. Hoffmann-La Roche AG: Key Financials

    Figure 46 F. Hoffmann-La Roche AG: Segmental Revenue

    Figure 47 F. Hoffmann-La Roche AG: Geographical Revenue

    Figure 48 Novartis International AG: Key Financials

    Figure 49 Novartis International AG: Segmental Revenue

    Figure 50 Novartis International AG: Geographical Revenue