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US Crohns Disease Market

ID: MRFR/Pharma/16396-HCR
100 Pages
Garvit Vyas
October 2025

US Crohn's Disease Market Research Report By Type (Ileocolitis, Ileitis, Granulomatous colitis, Gastroduodenal Crohn’s Disease, Jejunoileitis, Perianal Crohn’s Disease), By Treatment (Non-Surgical, Surgical) and By End User (Hospitals and Clinics, Research Institutes, Others) - Forecast to 2035

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US Crohns Disease Market Infographic
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US Crohns Disease Market Summary

As per MRFR analysis, the US Crohn's Disease Market Size was estimated at 3500.0 USD Million in 2024. The US crohns disease market is projected to grow from 3634.4 USD Million in 2025 to 5300.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 3.84% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US Crohn's disease market is experiencing a transformative shift towards personalized and integrated care solutions.

  • Personalized treatment approaches are gaining traction, reflecting a broader trend towards tailored healthcare solutions.
  • Digital health integration is becoming increasingly prevalent, enhancing patient engagement and monitoring capabilities.
  • Regulatory changes and accelerated approvals are facilitating faster access to innovative therapies in the market.
  • The rising incidence of Crohn's disease and advancements in biologic therapies are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 3500.0 (USD Million)
2035 Market Size 5300.0 (USD Million)
CAGR (2025 - 2035) 3.84%

Major Players

AbbVie (US), Johnson & Johnson (US), Amgen (US), Bristol-Myers Squibb (US), Takeda Pharmaceutical Company (JP), Merck & Co. (US), Gilead Sciences (US), Sanofi (FR), Celgene Corporation (US)

US Crohns Disease Market Trends

The crohns disease market is currently experiencing notable developments, driven by a combination of increasing prevalence and advancements in treatment options. The rising awareness of this chronic inflammatory bowel condition has led to a greater demand for effective therapies and management strategies. Healthcare providers are focusing on personalized medicine, which appears to enhance patient outcomes. Furthermore, the integration of digital health technologies is transforming how patients manage their condition, offering innovative solutions for monitoring and treatment adherence. In addition, the regulatory landscape is evolving, with agencies emphasizing the need for rapid approval of new therapies. This shift may facilitate quicker access to novel treatments for patients suffering from crohns disease. The market is also witnessing a surge in research initiatives aimed at understanding the underlying mechanisms of the disease, which could lead to the development of more targeted therapies. Overall, the crohns disease market is poised for growth, reflecting a commitment to improving patient care and outcomes.

Personalized Treatment Approaches

The trend towards personalized medicine is gaining traction within the crohns disease market. Tailoring treatment plans to individual patient profiles may enhance therapeutic efficacy and minimize adverse effects. This approach is supported by advancements in genetic research and biomarker identification, which could lead to more effective management strategies.

Digital Health Integration

The incorporation of digital health technologies is reshaping the landscape of the crohns disease market. Mobile applications and telehealth services are emerging as vital tools for patient engagement and self-management. These innovations may improve adherence to treatment regimens and facilitate real-time monitoring of symptoms.

Regulatory Changes and Accelerated Approvals

Recent regulatory changes are influencing the crohns disease market by streamlining the approval process for new therapies. This shift is likely to expedite access to innovative treatments, thereby enhancing the therapeutic options available to patients. The focus on rapid approval may also encourage pharmaceutical companies to invest in research and development.

US Crohns Disease Market Drivers

Rising Awareness and Advocacy

The growing awareness and advocacy surrounding Crohns disease play a crucial role in shaping the crohns disease market. Increased public knowledge about the condition, driven by campaigns and educational initiatives, has led to earlier diagnoses and improved access to care. Advocacy groups are actively working to promote research funding and support for patients, which may lead to enhanced treatment options. As awareness continues to rise, more individuals are likely to seek medical attention, thereby increasing the patient population and driving demand for therapies. This heightened awareness is expected to contribute positively to the growth trajectory of the crohns disease market, as stakeholders recognize the importance of addressing this chronic condition.

Advancements in Biologic Therapies

The development of biologic therapies has revolutionized the treatment landscape for Crohns disease, serving as a crucial driver for the crohns disease market. These therapies, which target specific components of the immune system, have shown promising efficacy in managing moderate to severe cases. The market for biologics is projected to reach approximately $10 billion by 2026, reflecting a compound annual growth rate (CAGR) of around 8%. As more biologic options become available, healthcare providers are likely to adopt these treatments, leading to improved patient outcomes. Additionally, ongoing clinical trials and research into new biologic agents may further enhance the therapeutic arsenal, thereby stimulating growth in the crohns disease market.

Rising Incidence of Crohns Disease

The increasing prevalence of Crohns disease in the US is a primary driver for the Crohn's disease market. Recent estimates suggest that approximately 780,000 individuals are affected by this condition in the US, with a notable rise in diagnoses over the past decade. This trend is likely attributed to a combination of genetic, environmental, and lifestyle factors. As the patient population grows, the demand for effective treatment options intensifies, prompting pharmaceutical companies to invest in research and development. The crohns disease market is expected to expand significantly as healthcare providers seek innovative therapies to manage symptoms and improve patient quality of life. Furthermore, the rising incidence may lead to increased awareness and education about the disease, further driving market growth.

Increased Focus on Patient-Centric Care

The shift towards patient-centric care is significantly influencing the crohns disease market. Healthcare providers are increasingly prioritizing individualized treatment plans that consider patients' unique needs and preferences. This approach not only enhances patient satisfaction but also improves adherence to treatment regimens. As a result, pharmaceutical companies are compelled to develop therapies that align with this trend, leading to a broader range of options for patients. The emphasis on patient engagement and education is likely to foster a more informed patient population, which may drive demand for innovative therapies. Consequently, the crohns disease market is expected to benefit from this paradigm shift, as patient-centric strategies become integral to treatment protocols.

Growing Investment in Research and Development

Investment in research and development (R&D) for Crohns disease is a vital driver of the crohns disease market. Pharmaceutical companies are increasingly allocating resources to discover new therapies and improve existing ones. This trend is evidenced by the substantial funding directed towards clinical trials and innovative treatment modalities. In 2025, R&D spending in the gastrointestinal disease sector is projected to exceed $5 billion, highlighting the commitment to advancing treatment options for Crohns disease. As new therapies emerge from these investments, the market is likely to experience significant growth, driven by the introduction of novel agents that address unmet medical needs and enhance patient outcomes.

Market Segment Insights

By Type: Ileocolitis (Largest) vs. Ileitis (Fastest-Growing)

In the US crohns disease market, the segment values show a varied distribution of market share, with Ileocolitis being the largest segment, significantly contributing to the overall revenues due to its widespread prevalence. Ileitis, while smaller in comparison, is witnessing a rapid increase in patient diagnoses and treatment demands, making it an essential part of the market landscape. Other types, including Granulomatous colitis and Gastroduodenal Crohn’s Disease, also hold their share, but do not dominate market dynamics as prominently as these two segments. The growth trends in this segment are primarily driven by an increase in the incidence rates of Crohn’s disease and heightened awareness among healthcare professionals and patients. The advancements in diagnostic techniques and treatment options are contributing to the emergence of Ileitis as a fastest-growing segment. Additionally, targeted therapies and biologics are leading to improved management of symptoms, which is boosting patient adoption and subsequently enriching market growth.

Ileocolitis (Dominant) vs. Ileitis (Emerging)

Ileocolitis is recognized as the dominant segment in the US crohns disease market due to its high prevalence and the significant challenges it poses to patients, necessitating robust management strategies. Characterized by inflammation of the colon and ileum, it often leads to severe symptoms impacting quality of life. On the other hand, Ileitis is emerging rapidly, reflecting a notable shift in treatment paradigms and increased awareness. As a growing segment, it particularly attracts attention with advancements in therapy that address the unique challenges faced by patients. Both segments highlight the diverse manifestations of Crohn's disease and underscore the need for tailored therapeutic approaches.

By Treatment: Non-Surgical (Largest) vs. Surgical (Fastest-Growing)

In the US crohns disease market, the Non-Surgical treatment segment holds the largest share, dominating the overall treatment landscape. This can be attributed to the increasing adoption of biologics and immunomodulators, which are effective in managing symptoms and inducing remission among patients. The Non-Surgical segment has a substantial market share as it includes various therapies that cater to a wide range of patient needs, allowing for accessible and personalized treatment options. Conversely, the Surgical segment is recognized as the fastest-growing area in the market. This surge in growth can be linked to the rising prevalence of complex cases of Crohn's disease that require surgical intervention. Advances in technology and minimally invasive procedures are also propelling this segment forward. Healthcare providers are more frequently recommending surgical options for patients who do not respond to medical therapies, contributing to its rapid growth trajectory.

Non-Surgical (Dominant) vs. Surgical (Emerging)

The Non-Surgical treatment segment remains dominant in the US crohns disease market due to its comprehensive range of medical interventions such as corticosteroids, biologics, and nutritional support therapies. These treatments effectively address inflammation and aim to maintain long-term remission for patients. The expanding array of treatment options tailored to individual patient profiles enhances the appeal of Non-Surgical therapies. On the other hand, the Surgical segment is emerging as a vital alternative for patients with severe complications or refractory disease not responsive to pharmacological treatments. With an increase in surgical techniques and improvements in post-operative care, patients are experiencing better outcomes, driving further interest and investment in this area of treatment.

By End-User: Hospitals and Clinics (Largest) vs. Research Institutes (Fastest-Growing)

In the US crohns disease market, the distribution of end-user segments reveals a significant concentration in hospitals and clinics, which hold the largest share. These facilities play a crucial role in providing specialized care for patients with Crohn's disease, contributing to their dominance within the market. Research institutes, while smaller in share, are vital for driving innovation and understanding the disease, offering essential support through clinical studies and trials. Growth trends in the end-user segment indicate a rapidly expanding role for research institutes. Their focus on developing new therapies and treatment modalities has positioned them as a rapidly emerging force within the market. Furthermore, the increasing collaboration between research entities and healthcare providers is set to enhance care quality, thus stimulating higher demand in this area.

Hospitals and Clinics (Dominant) vs. Research Institutes (Emerging)

Hospitals and clinics are characterized by their extensive infrastructure, specialized medical staff, and comprehensive patient care services, which make them the dominant player in the US crohns disease market. Their large patient turnover and ability to provide multidisciplinary treatment options contribute to their strong market presence. In contrast, research institutes are gaining ground as they focus on innovative research and clinical trials aimed at understanding Crohn's disease better. They attract significant funding and are pivotal in translating research findings into clinical practice, thus representing an emerging segment dedicated to improving therapeutic options and patient outcomes.

Get more detailed insights about US Crohns Disease Market

Key Players and Competitive Insights

The crohns disease market is characterized by a dynamic competitive landscape, driven by increasing prevalence rates and a growing demand for innovative therapies. Major players such as AbbVie (US), Johnson & Johnson (US), and Merck & Co. (US) are at the forefront, each adopting distinct strategies to enhance their market presence. AbbVie (US) continues to leverage its strong portfolio of biologics, focusing on research and development to introduce next-generation therapies. Meanwhile, Johnson & Johnson (US) emphasizes strategic partnerships and collaborations to expand its therapeutic offerings, particularly in the realm of personalized medicine. Merck & Co. (US) is also investing heavily in digital transformation initiatives, aiming to optimize patient engagement and streamline clinical trials, thereby enhancing its competitive edge.

The business tactics employed by these companies reflect a concerted effort to localize manufacturing and optimize supply chains, which are crucial in a moderately fragmented market. This competitive structure allows for a diverse range of treatment options, while the collective influence of these key players shapes market dynamics. The focus on localized production not only reduces costs but also enhances responsiveness to regional market demands, thereby fostering a more resilient supply chain.

In October 2025, AbbVie (US) announced the launch of a new clinical trial aimed at evaluating the efficacy of its latest biologic therapy for crohns disease. This strategic move underscores AbbVie's commitment to innovation and its proactive approach to addressing unmet medical needs. By investing in clinical research, AbbVie (US) positions itself to potentially capture a larger market share, particularly among patients seeking advanced treatment options.

In September 2025, Johnson & Johnson (US) entered into a partnership with a leading biotech firm to co-develop a novel therapeutic agent targeting crohns disease. This collaboration is indicative of Johnson & Johnson's strategy to enhance its product pipeline through synergistic alliances. Such partnerships not only accelerate the development process but also diversify the company's offerings, thereby strengthening its competitive position in the market.

In August 2025, Merck & Co. (US) unveiled a new digital platform designed to facilitate patient access to clinical trial information and treatment options for crohns disease. This initiative reflects Merck's focus on integrating technology into its operations, aiming to improve patient engagement and streamline the clinical trial process. By enhancing accessibility, Merck (US) is likely to foster greater patient participation, which could lead to more robust data collection and improved treatment outcomes.

As of November 2025, current trends in the crohns disease market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) into therapeutic development. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is expected to evolve, with a notable shift from price-based competition towards a focus on technological advancements, innovative therapies, and reliable supply chains. This transition may ultimately redefine the landscape, positioning companies that prioritize innovation and patient-centric solutions at the forefront of the market.

Key Companies in the US Crohns Disease Market market include

Industry Developments

Recent developments in the US Crohn's Disease Market have been significant, with several pharmaceutical companies advancing their treatments and therapies. In June 2023, AbbVie received FDA approval for a new indication for its drug Rinvoq, enhancing its position in the market for treating Crohn's Disease. Meanwhile, Takeda continues to expand its efforts with the development of new biologics, contributing to innovative treatment options. In March 2023, Merck and Co announced a strategic partnership with a biotech company to boost its pipeline in inflammatory bowel diseases, aiming to enhance patient outcomes.

The market has demonstrated strong growth potential, driven by increasing awareness and diagnosis of Crohn's Disease across the US. Major companies like Pfizer, Bristol-Myers Squibb, and Gilead Sciences are also increasing their investments in Research and Development activities focused on this condition to capture growing demand. Notably, in July 2022, AstraZeneca acquired a smaller biotech firm with promising therapies for inflammatory bowel diseases, strengthening its Crohn's Disease portfolio. Overall, these developments reflect a dynamic market landscape with active participation from leading pharmaceutical companies dedicated to addressing the unmet needs of patients suffering from Crohn's Disease in the US.

Future Outlook

US Crohns Disease Market Future Outlook

The Crohns Disease Market is projected to grow at a 3.84% CAGR from 2024 to 2035, driven by increasing prevalence, advancements in treatment options, and rising healthcare expenditure.

New opportunities lie in:

  • Development of personalized biologic therapies for targeted treatment.
  • Expansion of telehealth services for remote patient monitoring.
  • Investment in AI-driven diagnostic tools to enhance early detection.

By 2035, the market is expected to achieve substantial growth, reflecting evolving treatment paradigms and increased patient access.

Market Segmentation

US Crohns Disease Market Type Outlook

  • Ileocolitis
  • Ileitis
  • Granulomatous colitis
  • Gastroduodenal Crohn’s Disease
  • Jejunoileitis
  • Perianal Crohn’s Disease

US Crohns Disease Market End-User Outlook

  • Hospitals and Clinics
  • Research Institutes

US Crohns Disease Market Treatment Outlook

  • Non-Surgical
  • Surgical

Report Scope

MARKET SIZE 2024 3500.0(USD Million)
MARKET SIZE 2025 3634.4(USD Million)
MARKET SIZE 2035 5300.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 3.84% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled AbbVie (US), Johnson & Johnson (US), Amgen (US), Bristol-Myers Squibb (US), Takeda Pharmaceutical Company (JP), Merck & Co. (US), Gilead Sciences (US), Sanofi (FR), Celgene Corporation (US)
Segments Covered Type, Treatment, End-User
Key Market Opportunities Advancements in biologics and personalized medicine enhance treatment options in the crohns disease market.
Key Market Dynamics Rising demand for biologics drives innovation and competition in the Crohn's disease treatment landscape.
Countries Covered US

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FAQs

What is the expected market size of the US Crohn's Disease Market by 2024?

The US Crohn's Disease Market is expected to be valued at 2.75 billion USD by 2024.

What will the market value of the US Crohn's Disease Market be in 2035?

In 2035, the overall market is projected to reach 4.21 billion USD.

What is the expected compound annual growth rate (CAGR) for the US Crohn's Disease Market from 2025 to 2035?

The market is expected to grow at a CAGR of 3.93% during the forecast period from 2025 to 2035.

Which segment of the US Crohn's Disease Market will have the highest valuation by 2035?

The Ileocolitis segment is expected to be valued at 1.79 billion USD by 2035.

What is the market size of the Ileitis segment in the US Crohn's Disease Market for 2024?

The Ileitis segment is valued at 0.65 billion USD in the year 2024.

Which company is a major player in the US Crohn's Disease Market?

Merck and Co is one of the significant players in the US Crohn's Disease Market.

What market value is projected for Granulomatous colitis segment by 2035?

The Granulomatous colitis segment is estimated to reach 0.69 billion USD by 2035.

What are some key applications driving the growth of the US Crohn's Disease Market?

Key applications include treatments for various types of Crohn's Disease, including Ileocolitis and Ileitis.

What opportunities exist within the US Crohn's Disease Market for emerging trends?

The market presents opportunities for innovative therapies and improved patient management strategies.

How is the growth trajectory of the Gastroduodenal Crohn’s Disease segment expected to evolve by 2035?

The Gastroduodenal Crohn’s Disease segment is projected to grow to 0.47 billion USD by 2035.

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