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South America Geographic Atrophy (GA) Market

ID: MRFR/HC/49913-HCR
200 Pages
Rahul Gotadki
October 2025

South America Geographic Atrophy GA Market Research Report By Age Group (Above 60 Years, Above 75 Years), By Diagnosis (Fundus Autofluorescence, Optical Coherence Tomography Angiography, Multifocal Electroretinography), By Therapeutic Agents Clinical Phase (Late-Stage, Phase II, Phase I, Pre-Clinical Stage, Discovery Candidates) and By Regional (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035

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South America Geographic Atrophy (GA) Market Infographic
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South America Geographic Atrophy (GA) Market Summary

As per MRFR analysis, the South America geographic atrophy market size was estimated at 1200.0 USD Million in 2024. The South America geographic atrophy-ga market is projected to grow from 1287.36 USD Million in 2025 to 2600.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 7.28% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America geographic atrophy market is poised for growth driven by demographic shifts and advancements in treatment options.

  • The incidence of age-related macular degeneration is rising, particularly in Brazil, which remains the largest market in the region.
  • Advancements in treatment modalities are expected to enhance patient outcomes and drive market expansion across South America.
  • Regulatory changes are facilitating improved market access, especially in Mexico, the fastest-growing region for geographic atrophy treatments.
  • Key market drivers include the increasing aging population and rising healthcare expenditure, which are likely to propel market growth.

Market Size & Forecast

2024 Market Size 1200.0 (USD Million)
2035 Market Size 2600.0 (USD Million)

Major Players

Novartis (CH), Regeneron Pharmaceuticals (US), Roche (CH), Bayer (DE), Alcon (CH), Apellis Pharmaceuticals (US), Genentech (US), Santen Pharmaceutical (JP), Horizon Therapeutics (IE)

South America Geographic Atrophy (GA) Market Trends

The geographic atrophy-ga market in South America is currently experiencing notable developments, driven by an increasing prevalence of age-related macular degeneration (AMD) among the aging population. This condition, characterized by the progressive degeneration of retinal cells, has led to a growing demand for effective treatment options. As healthcare systems in various South American countries evolve, there is a heightened focus on innovative therapies and technologies aimed at managing this debilitating condition. Furthermore, the collaboration between local healthcare providers and international pharmaceutical companies appears to be fostering advancements in research and development, potentially leading to new therapeutic solutions. In addition, the regulatory landscape in South America is gradually adapting to accommodate emerging treatments for geographic atrophy. Governments are recognizing the need for improved access to care and are implementing policies that may facilitate the approval and distribution of novel therapies. This shift could enhance patient outcomes and increase market opportunities for stakeholders involved in the geographic atrophy-ga market. Overall, the combination of demographic trends, evolving healthcare policies, and collaborative efforts among industry players suggests a dynamic environment for the geographic atrophy-ga market in South America.

Rising Incidence of Age-Related Macular Degeneration

The geographic atrophy-ga market is witnessing a surge in demand due to the increasing incidence of age-related macular degeneration among older adults. As populations age, the prevalence of this condition is expected to rise, prompting a greater need for effective treatment options.

Advancements in Treatment Modalities

Innovative treatment modalities are emerging within the geographic atrophy-ga market, driven by ongoing research and development efforts. These advancements may include novel pharmacological therapies and cutting-edge technologies aimed at improving patient outcomes.

Regulatory Changes Enhancing Market Access

Recent regulatory changes in South America are likely to enhance market access for new therapies targeting geographic atrophy. Governments are increasingly focused on streamlining approval processes, which may facilitate quicker access to innovative treatments for patients.

South America Geographic Atrophy (GA) Market Drivers

Increasing Aging Population

The demographic shift towards an older population in South America is a crucial driver for the geographic atrophy-ga market. As individuals age, the risk of developing age-related eye diseases, including geographic atrophy, escalates. Current estimates suggest that by 2030, approximately 20% of the South American population will be over 60 years old. This growing segment is likely to increase the demand for diagnostic and therapeutic options in the geographic atrophy-ga market. Furthermore, healthcare systems may need to adapt to accommodate the rising prevalence of this condition, potentially leading to increased funding and resources allocated to eye health initiatives. The aging population's impact on healthcare infrastructure could also stimulate innovation in treatment modalities, thereby enhancing the overall market landscape.

Rising Healthcare Expenditure

Healthcare expenditure in South America has been on an upward trajectory, which appears to positively influence the geographic atrophy-ga market. Increased spending on healthcare services, projected to reach $1 trillion by 2025, allows for better access to advanced diagnostic tools and treatment options for geographic atrophy. This financial commitment from both public and private sectors may facilitate the introduction of innovative therapies and technologies, thereby improving patient outcomes. Additionally, as healthcare budgets expand, there is a potential for increased awareness and education regarding geographic atrophy, leading to earlier diagnosis and intervention. This trend could ultimately drive market growth as more patients seek treatment for this debilitating condition.

Technological Advancements in Diagnostics

Technological innovations in diagnostic tools are significantly shaping the geographic atrophy-ga market in South America. Enhanced imaging techniques, such as optical coherence tomography (OCT), are becoming more widely available, allowing for earlier and more accurate detection of geographic atrophy. The adoption of these advanced technologies is likely to improve patient management and treatment outcomes. As healthcare providers increasingly utilize these tools, the demand for related services and products is expected to rise. Furthermore, the integration of artificial intelligence in diagnostic processes may streamline workflows and enhance the precision of diagnoses, potentially leading to a more robust geographic atrophy-ga market. This trend indicates a shift towards more proactive healthcare approaches in managing eye diseases.

Growing Awareness and Education Initiatives

Awareness campaigns and educational initiatives regarding geographic atrophy are gaining momentum in South America. Organizations and healthcare providers are increasingly focusing on informing the public about the risks and symptoms associated with this condition. Such efforts are likely to lead to higher rates of early diagnosis and treatment, which could positively impact the geographic atrophy-ga market. Increased awareness may also encourage individuals to seek regular eye examinations, further driving demand for diagnostic services. As more patients become informed about their options, the market may experience growth in both preventive measures and therapeutic interventions. This trend underscores the importance of education in enhancing patient outcomes and fostering a more informed patient population.

Regulatory Support for Innovative Therapies

Regulatory bodies in South America are increasingly supportive of innovative therapies for geographic atrophy, which may significantly influence the market landscape. Streamlined approval processes for new treatments can facilitate quicker access to cutting-edge therapies for patients. This regulatory environment appears to encourage pharmaceutical companies to invest in research and development, potentially leading to a wider array of treatment options. As new therapies enter the market, competition may intensify, driving down costs and improving accessibility for patients. The proactive stance of regulatory agencies in promoting innovation could thus play a pivotal role in shaping the future of the geographic atrophy-ga market, ensuring that patients have access to the latest advancements in care.

Market Segment Insights

By Age Group: Above 60 Years (Largest) vs. Above 75 Years (Fastest-Growing)

In the market, the distribution of demographic segments indicates that individuals above 60 years constitute the largest share, reflecting the aging population trend prevalent in South America. This segment is critical as it encompasses a wide range of age-related pathologies, contributing significantly to the demand for geographic atrophy treatments. Conversely, the group above 75 years is emerging as the fastest-growing segment, driven by increased life expectancy and rising awareness about age-related eyesight degeneration. Innovations in treatment options and preventive care are fueling this growth, making it an area of strategic importance for market players looking to expand their reach in aging populations.

Above 60 Years (Dominant) vs. Above 75 Years (Emerging)

The segment comprising individuals above 60 years is currently the dominant force in the market, benefiting from a larger population base and established health care frameworks addressing age-related illnesses. This demographic is characterized by higher incidence rates of geographic atrophy, prompting significant investment in specialized treatments. In contrast, the above 75 years segment is recognized as the emerging market force, characterized by rapid growth due to a surge in this age cohort's number. This group often presents unique challenges, including increased medical complexities, necessitating tailored solutions and innovative interventions to effectively address their specific needs.

By Diagnosis: Fundus Autofluorescence (FAF) (Largest) vs. Optical Coherence Tomography Angiography (OCT-A) (Fastest-Growing)

In the market, Fundus Autofluorescence (FAF) holds the largest share among the diagnostic methods, driven by its ability to visualize retinal health effectively. This technique has gained considerable traction among clinicians for its non-invasive nature and informative imaging capabilities. On the other hand, Optical Coherence Tomography Angiography (OCT-A) is rapidly gaining market share due to its advanced imaging technology, providing detailed views of vascular structures in the eye, essential in monitoring geographic atrophy. The growth trends show that OCT-A is emerging as the fastest-growing diagnostic method, attracting investment and interest from research institutions and ophthalmic clinics. The increase in the aging population, coupled with the rise in diabetic and age-related macular degeneration cases, drives the demand for these technologies. Furthermore, ongoing advancements in imaging modalities and enhanced diagnosis accuracy are pivotal in expanding the adoption of these diagnostic tools in ophthalmology, making both FAF and OCT-A essential in clinical settings.

Fundus Autofluorescence (Dominant) vs. Optical Coherence Tomography Angiography (Emerging)

Fundus Autofluorescence (FAF) is the dominant diagnostic tool in the market, known for its efficacy in detecting retinal diseases through the visualization of lipofuscin accumulation. FAF's non-invasive approach has made it a preferred choice among ophthalmologists, allowing for thorough monitoring of retinal conditions. On the other hand, Optical Coherence Tomography Angiography (OCT-A) is an emerging technology that has gained popularity due to its ability to provide high-resolution images of ocular blood vessels without the need for dye injections. This technology supports better assessment of microvascular changes associated with geographic atrophy, thus driving its rapid adoption in clinical practice. Both methods complement each other, catering to the diagnostic needs of various retinal conditions.

By Therapeutic Agents Clinical Phase: Late-Stage (Largest) vs. Phase II (Fastest-Growing)

The market for therapeutic agents in the segment features a distinct distribution of clinical phases. The Late-Stage (Phase III) segment holds the largest market share, reflecting the significant investment and progression of several leading candidates in the development pipeline. Following behind, Phase II candidates exhibit notable activity with promising prospects, while Phase I and pre-clinical stages continue to contribute to the expanding therapeutic landscape, albeit at smaller proportions. Growth trends indicate a strong focus on advancing late-stage candidates, driven by increasing demand for effective treatments and investment in research and development. Furthermore, Phase II candidates are emerging as the fastest-growing segment, bolstered by favorable regulatory environments and heightened interest from pharmaceutical companies aiming to capitalize on the unmet needs in the geographic atrophy domain. These dynamics are likely to shape the strategic directions of stakeholders in this market.

Late-Stage (Dominant) vs. Phase II (Emerging)

In the segment comparison, Late-Stage (Phase III) therapeutic agents are currently dominant, characterized by robust clinical data supporting their efficacy and safety, which fosters confidence among clinicians and reimbursement bodies. These agents are positioned for near-term market entry and have significant backing from research institutions and biopharmaceutical companies. In contrast, Phase II agents are emerging with considerable potential; they showcase innovative mechanisms of action that could redefine treatment paradigms. This segment is witnessing rapid advancements and partnerships, attracting investments aimed at expediting their progression to late-stage trials, thus highlighting a dynamic shift towards new therapeutic options for managing geographic atrophy.

Get more detailed insights about South America Geographic Atrophy (GA) Market

Regional Insights

Brazil : Robust Growth and Demand Trends

Brazil holds a commanding market share of 60% in the South American geographic atrophy (GA) market, valued at $600.0 million. Key growth drivers include an aging population, increasing awareness of eye health, and advancements in treatment options. Regulatory support from the Brazilian Health Regulatory Agency (ANVISA) has facilitated faster approvals for innovative therapies. Additionally, investments in healthcare infrastructure and telemedicine are enhancing access to treatments across urban and rural areas.

Mexico : Growing Demand and Investment Opportunities

Mexico accounts for 25% of the South American GA market, valued at $250.0 million. The growth is driven by rising healthcare expenditure and increasing prevalence of age-related eye diseases. Government initiatives aimed at enhancing healthcare infrastructure and public awareness campaigns are pivotal in driving demand. The regulatory environment is becoming more favorable, with streamlined processes for drug approvals, which is crucial for market expansion.

Argentina : Focus on Healthcare Accessibility

Argentina represents 20% of the South American GA market, valued at $200.0 million. The market is supported by a growing elderly population and increasing healthcare investments. However, economic instability poses challenges to consistent growth. Regulatory reforms are underway to improve drug accessibility, and local initiatives are focusing on enhancing patient education regarding GA. The demand for innovative therapies is rising, driven by both public and private healthcare sectors.

Rest of South America : Varied Growth Across Regions

The Rest of South America holds a 15% market share in the GA sector, valued at $150.0 million. This sub-region includes countries like Chile, Colombia, and Peru, each with distinct healthcare landscapes. Growth is driven by increasing awareness of GA and government initiatives to improve healthcare access. However, disparities in infrastructure and regulatory environments can hinder uniform growth. Local players are emerging, but major The geographic atrophy-ga market.

South America Geographic Atrophy (GA) Market Regional Image

Key Players and Competitive Insights

The geographic atrophy-ga market in South America is characterized by a competitive landscape that is increasingly dynamic, driven by a combination of innovation, strategic partnerships, and regional expansion. Key players such as Novartis (CH), Regeneron Pharmaceuticals (US), and Roche (CH) are actively shaping the market through their focused operational strategies. Novartis (CH) emphasizes innovation in treatment modalities, particularly in gene therapy, which appears to be a focal point for addressing unmet medical needs. Regeneron Pharmaceuticals (US) is leveraging its robust pipeline of monoclonal antibodies, indicating a commitment to enhancing therapeutic options. Meanwhile, Roche (CH) is concentrating on expanding its diagnostic capabilities, which could potentially complement its therapeutic offerings, thereby creating a more integrated approach to patient care.

The business tactics employed by these companies reflect a nuanced understanding of the market's structure, which is moderately fragmented yet increasingly competitive. Localizing manufacturing and optimizing supply chains are pivotal strategies that these companies are adopting to enhance operational efficiency and reduce costs. The collective influence of these key players suggests a trend towards consolidation, as companies seek to strengthen their market positions through strategic collaborations and acquisitions.

In October 2025, Novartis (CH) announced a partnership with a local biotechnology firm to co-develop a novel treatment for geographic atrophy, which underscores its commitment to regional innovation. This collaboration not only enhances Novartis's product pipeline but also allows for localized insights into patient needs, potentially leading to more effective therapies. Similarly, in September 2025, Regeneron Pharmaceuticals (US) expanded its clinical trials in Brazil, focusing on a new monoclonal antibody that targets geographic atrophy. This move indicates a strategic effort to tap into the growing South American market, where the prevalence of age-related macular degeneration is rising.

In August 2025, Roche (CH) launched a new diagnostic tool aimed at early detection of geographic atrophy, which could significantly alter treatment paradigms. This initiative reflects Roche's strategy to integrate diagnostics with therapeutics, thereby enhancing patient outcomes and positioning itself as a leader in comprehensive care solutions. Furthermore, in July 2025, Bayer (DE) announced an investment in digital health technologies to improve patient engagement and adherence to treatment regimens, suggesting a shift towards more patient-centric approaches in the market.

As of November 2025, current competitive trends are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) into healthcare solutions. Strategic alliances are becoming more prevalent, as companies recognize the value of collaborative innovation in addressing complex healthcare challenges. The competitive differentiation in this market is likely to evolve from traditional price-based competition to a focus on innovation, technology, and the reliability of supply chains. This shift may ultimately lead to enhanced patient outcomes and a more sustainable healthcare ecosystem in South America.

Key Companies in the South America Geographic Atrophy (GA) Market market include

Industry Developments

In the South America Geographic Atrophy (GA) Market, recent developments indicate a notable increase in Research and Development investments focusing on therapeutic options and diagnostic tools targeted at retinal diseases. Companies such as Novartis and Bayer are making strides with innovative treatment approaches, while Alcon has expanded its product offering in the region to cater to the growing demand for ophthalmic solutions. In September 2023, EyeGate Pharmaceuticals announced an agreement with a South American distributor to enhance the availability of its GA treatments.

Additionally, Kowa Company reported improved market penetration through partnerships with local health authorities in Brazil. Notably, in August 2023, Roche expanded its collaboration with Astellas Pharma, aiming to accelerate the development of new therapies for macular degeneration, thus strengthening their presence in the South American market. The valuation of the Geographic Atrophy market is expected to rise due to increasing patient awareness and government initiatives to support eye health, particularly in Argentina and Chile.

Over the past couple of years, significant efforts to increase accessibility to treatments have been observed, contributing positively to the evolving landscape of the Geographic Atrophy market in South America.

Future Outlook

South America Geographic Atrophy (GA) Market Future Outlook

The geographic atrophy-ga market is projected to grow at a 7.28% CAGR from 2024 to 2035, driven by increasing prevalence and advancements in treatment options.

New opportunities lie in:

  • Development of telemedicine platforms for remote patient monitoring
  • Investment in AI-driven diagnostic tools for early detection
  • Expansion of specialized clinics focusing on geographic atrophy treatment

By 2035, the market is expected to achieve substantial growth and innovation.

Market Segmentation

South America Geographic Atrophy (GA) Market Age Group Outlook

  • Above 60 Years
  • Above 75 Years

South America Geographic Atrophy (GA) Market Diagnosis Outlook

  • Fundus Autofluorescence (FAF)
  • Optical Coherence Tomography Angiography (OCT-A)
  • Multifocal Electroretinography (MfERG)

South America Geographic Atrophy (GA) Market Therapeutic Agents Clinical Phase Outlook

  • Late-Stage (Phase III)
  • Phase II
  • Phase I
  • Pre-Clinical Stage & Discovery Candidates

Report Scope

MARKET SIZE 20241200.0(USD Million)
MARKET SIZE 20251287.36(USD Million)
MARKET SIZE 20352600.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)7.28% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Novartis (CH)", "Regeneron Pharmaceuticals (US)", "Roche (CH)", "Bayer (DE)", "Alcon (CH)", "Apellis Pharmaceuticals (US)", "Genentech (US)", "Santen Pharmaceutical (JP)", "Horizon Therapeutics (IE)"]
Segments CoveredAge Group, Diagnosis, Therapeutic Agents Clinical Phase
Key Market OpportunitiesEmerging therapies targeting geographic atrophy present significant growth potential in the evolving healthcare landscape.
Key Market DynamicsRising demand for innovative therapies drives competition and regulatory scrutiny in the geographic atrophy market.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Geographic Atrophy GA Market in 2024?

The South America Geographic Atrophy GA Market is expected to be valued at 1.11 USD Billion in 2024.

What is the projected market size for the South America Geographic Atrophy GA Market by 2035?

By 2035, the South America Geographic Atrophy GA Market is anticipated to reach a valuation of 2.24 USD Billion.

What is the expected CAGR for the South America Geographic Atrophy GA Market from 2025 to 2035?

The expected CAGR for the South America Geographic Atrophy GA Market during the forecast period from 2025 to 2035 is 6.579%.

Which country holds the largest market share in the South America Geographic Atrophy GA Market?

Brazil holds the largest market share in the South America Geographic Atrophy GA Market with a valuation of 0.45 USD Billion in 2024.

What is the projected market size for Argentina in the South America Geographic Atrophy GA Market by 2035?

By 2035, the market size for Argentina in the South America Geographic Atrophy GA Market is projected to reach 0.4 USD Billion.

Who are the key players in the South America Geographic Atrophy GA Market?

Key players in the market include major companies such as Novartis, Bayer, and Regeneron Pharmaceuticals.

What is the expected market size for the segment of individuals above 75 years in 2024?

The market size for individuals above 75 years is expected to be 0.38 USD Billion in 2024.

How does the Rest of South America region contribute to the Geographic Atrophy GA Market?

The Rest of South America region is valued at 0.21 USD Billion in 2024, contributing significantly to the overall market.

What market growth rate is expected for Brazil specifically between 2025 and 2035?

Brazil is expected to experience notable market growth with an increase from 0.45 USD Billion in 2024 to 0.91 USD Billion in 2035.

What are some key growth drivers for the South America Geographic Atrophy GA Market?

Key growth drivers include an aging population and advancements in treatment options for geographic atrophy.

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