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Solid Phase Extraction Market Analysis

ID: MRFR//6083-CR | 132 Pages | Author: Kinjoll Dey| December 2021

The solid phase extraction (SPE) instruments market is on the cusp of significant growth, especially in developing countries where burgeoning infrastructure and increased healthcare expenditure present ripe opportunities. The unique dynamics of these regions, marked by growing academic, biotechnology, and pharmaceutical industries, position them as key players in the future trajectory of the SPE instruments market.

One of the pivotal factors driving the growth of the SPE instruments market in developing countries is the ongoing development of infrastructure. As these nations invest in building robust infrastructure, there is a natural confluence with the increased need for advanced technologies in various sectors. Solid phase extraction instruments, with their versatile applications in areas such as biotechnology, pharmaceuticals, and environmental testing, find themselves at the forefront of meeting these emerging needs.

The escalating healthcare expenditure in developing countries is another crucial factor contributing to the expanding market for SPE instruments. As these nations prioritize and invest in healthcare infrastructure and services, there is a subsequent demand for cutting-edge technologies to support diagnostics, research, and treatment. SPE instruments, known for their efficiency in sample preparation and analysis, become integral components of the evolving healthcare landscape in these regions.

The growing academic sector in developing countries further fuels the demand for SPE instruments. Educational institutions and research centers increasingly recognize the importance of advanced analytical tools for their scientific endeavors. As a result, there is a rising need for SPE instruments in academic research, providing students and researchers with the necessary tools for experimentation and analysis.

Additionally, the burgeoning biotechnology and pharmaceutical industries in developing countries contribute significantly to the expansion of the SPE instruments market. These industries, characterized by rapid innovation and research, rely on sophisticated instruments for various applications, including drug development, quality control, and environmental monitoring. SPE instruments, with their precision and efficiency in sample preparation, become indispensable in these industries' quest for excellence.

However, one notable restraint to the growth of the SPE instruments market, not unique to developing countries, is the high cost associated with these products. The initial investment required for acquiring SPE instruments can be a limiting factor for many potential users, especially in resource-constrained settings. This presents a challenge for market players looking to penetrate these regions.

Nevertheless, the market is poised for growth, and one significant driver that will likely overcome the cost barrier is the introduction of new, low-cost SPE products. The industry's response to the need for more affordable options is expected to democratize access to these instruments, particularly in developing countries. This shift toward affordability aligns with the broader trend of making advanced technologies accessible across diverse socioeconomic landscapes.

In conclusion, developing countries offer a fertile ground for the growth of the solid phase extraction instruments market. The intersection of increasing infrastructure development, rising healthcare expenditure, and the expansion of academic and industrial sectors creates a conducive environment for the adoption of SPE instruments. As the industry addresses challenges related to cost and introduces more cost-effective solutions, the market in developing countries is poised for significant expansion, contributing to the global landscape of analytical instruments and technologies.

Covered Aspects:

Report Attribute/Metric Details
Segment Outlook Type, Application, and Region

Global Solid Phase Extraction Market Overview


Solid Phase Extraction Market Size was valued at USD 0.21 Billion in 2023. The Solid Phase Extraction market industry is projected to grow from USD 0.22 Billion in 2024 to USD 0.3 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 3.85% during the forecast period (2024 - 2032). Growing generics market, government funding of academia and life sciences, and instrumentation technology advancements, are the key market drivers enhancing the market growth.


Solid Phase Extraction Market1


Type Secondary Research, Primary Research, MRFR Database and Analyst Review


Solid Phase Extraction Market Trends


Growth in generics industry is driving the market growth


As a result of increased demand for drug development, the market for solid phase extraction equipment has expanded. As the generics sector is expected to account for more than 80% of the pharmaceutical market in the future years, the demand for SPE is projected to increase. For instance, Invest India (India) reports that generic drugs make up 71% of the Indian pharmaceutical business. The EU intends to establish laws that will significantly lower barriers for less priced biosimilars to enter the market, reducing the probability of future drug shortages, as was the case during the COVID-19 epidemic. According to Statista (Germany), over 65% of medications sold in European countries like Italy are generic.


The rising use of SPE consumables in the pharmaceutical industry is largely responsible for this market's growth. The growing demand for high-throughput sample analysis needs, LC-MS-MS techniques, and liquid chromatography-mass spectrometry (LC-MS) has led to a need for the SPE consumable in the pharmaceutical business. The rise in R&D spending in the medical industry has increased demand for SPE consumables. An further factor driving the growth of this market is the ongoing automation of the SPE processes that are replacing the older manual SPEs. Automated SPE has several benefits over manual SPE using a vacuum manifold, including increased laboratory productivity and a reduction in time and solvent use. These elements encourage market growth.


Furthermore, precision is quite important in the analysis. The necessity for automatic SPE is exacerbated by the manual SPE's variable precision from operator to operator, batch to batch, and sample to sample. However, issues with users' sample handling pose a significant barrier to the market's growth. The hefty initial setup expenses in addition to a workforce that lacks the requisite skills significantly restrict market expansion. However, ongoing advancements in SPE methods that have given rise to a new generation of SPE technologies are creating new chances for business growth. The SPE consumable business has a chance as research study funding from numerous organisations rises. For instance, in March 2018, the German Research Foundation gave four new sequencing sites in Germany more than USD 17 million.


Numerous technological developments have been made in the solid phase extraction (SPE) market in order to satisfy the requirements of the biotechnology and biopharmaceutical industries, as well as the food and beverage, chemical, semiconductor, and environmental testing sectors. These developments have made it possible to build compact, automated, and computerised devices. SPE gadgets are now easier to use and more practical thanks to technical improvements. Rising automation and technology development are anticipated to drive market expansion. For instance, in May 2019, Biotage (Sweden) unveiled its series of Atlantic ReadyDisk SPE discs. The ready-to-use SPE discs in this line save time by not requiring disc holders to be cleaned. The Strata-X-Drug B Plus SPE product for urine drug testing in forensic and clinical drug testing was made available by Phenomenex Inc. (US) in May 2018.


Thermo Scientific Dionex Auto Trace 280 PFAS SPE equipment, a fully automated SPE device for drinking water analysis, was also unveiled by Thermo Fisher Scientific Inc. (US) in March 2020. The OttoTM SPEcialist Positive Pressure Manifold, which tackles a weakness in current SPE devices by boosting dependability and reproducibility of results, was introduced by Waters Corp (US) in January 2021. Therefore, such product introductions and advancements are encouraging market expansion. Thus, driving the Solid Phase Extraction market revenue.


Solid Phase Extraction Market Segment Insights


Solid Phase Extraction Type Insights


The Solid Phase Extraction market segmentation, based on type, includes SPE disk, SPE cartridge, and others. SPE cartridge segment accounted for the largest revenue share in 2022. The SPE cartridge's rise is mostly attributed to its acceptance in the food, environmental protection, commodities inspection, and pesticide residues application industries. By avoiding voiding, clogging, and channelling, the use of SPE cartridges benefits the market by lowering the expense of expensive reanalysis of bioanalytical samples.


Solid Phase Extraction Application Insights


The Solid Phase Extraction market segmentation, based on application, includes pharmaceutical industries, academic & research institutes, environmental, hospitals & clinics, and others. Environmental segment dominated the  Solid Phase Extraction market in 2022. This is because there is a growing need for pretreatment due to the size of the water sample.


Figure 1 Solid Phase Extraction Market, by Application, 2022 & 2032 (USD Billion)Solid Phase Extraction Market, by Application, 2022 & 2032


Type Secondary Research, Primary Research, MRFR Database and Analyst Review


Solid Phase Extraction Regional Insights


By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The Asia Pacific Solid Phase Extraction market dominated this market in 2022 (45.80%). The most recent developments in instrumentation, shifting economic conditions, expanding biotechnology investment, and pharmaceutical research organisations in Asia-Pacific emerging countries are the key drivers of this increase. Moreover, China’s Solid Phase Extraction market held the largest market share, and the Indian Solid Phase Extraction market was the fastest growing market in the Asia-Pacific region.


Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2 SOLID PHASE EXTRACTION MARKET SHARE BY REGION 2022 (USD Billion)SOLID PHASE EXTRACTION MARKET SHARE BY REGION 2022


Type Secondary Research, Primary Research, MRFR Database and Analyst Review


The North America Solid Phase Extraction Market is expected to register significant growth from 2023 to 2032. This is mainly due to its growing use in a variety of sectors, including the pharmaceutical, biotechnology, agricultural, and other industries. Pharmaceutical companies in the United States have access to numerous contemporary laboratory and development facilities. In terms of worldwide market penetration and revenue generation, the United States and Canada are strong countries. Further, the U.S. Solid Phase Extraction market held the largest market share, and the Canada Solid Phase Extraction market was the fastest growing market in the North America region.


Europe Solid Phase Extraction market accounted for the healthy market share in 2022. SPE products are frequently used in the R&D of medications by research organisations and biopharmaceutical companies. The government's measures to support such projects are causing the market in the region to expand. Further, the German Solid Phase Extraction market held the largest market share, and the U.K Solid Phase Extraction market was the fastest growing market in the European region


Solid Phase Extraction Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development in order to expand their product lines, which will help the Solid Phase Extraction market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their  footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Solid Phase Extraction industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the  Solid Phase Extraction industry to benefit clients and increase the market sector. In recent years, the Solid Phase Extraction industry has offered some of the most significant advantages to medicine. Major players in the Solid Phase Extraction market, including Thermo Fisher Scientific, PerkinElmer Inc., 3M, Gilson Incorporated, Gerstel GmbH & Co. KG, Merck KGaA, Agilent Technologies, GL Sciences Inc., Biotage AB, Waters Corporation, Tecan Trading AG, Cytiva, Pall Corporation, Phenomenex Inc., and Sigma-Aldrich, are attempting to increase market demand by investing in research and development operations.


Thermo Fisher Scientific Inc. (Thermo Fisher) delivers medical equipment, analytical instruments, reagents and consumables, software, and services to satisfy the demands of challenging analytical challenges in research, diagnostics, and clinical laboratories. It offers solutions for cellular biology, synthetic biology, and flow cytometry. Mass spectrometry, genetic sequencing, electron microscopy, protein, and molecular biology research equipment are just a few of the many products that the company sells. The company offers services to companies in the environmental, industrial quality, and process control sectors, as well as to academic and research institutes, governmental organisations, pharmaceutical and biotech companies, clinical diagnostic laboratories, and environmental companies. It provides its products and services through its direct sales force, online sales, and third-party distributors across the Americas, Asia-Pacific, and Europe. The headquarters of Thermo Fisher are located in Waltham, Massachusetts, in the US. In April 2020, Thermo Fisher Scientific unveiled Dionex AutoTrace 280 PFAS. The Thermo Scientific Dionex AutoTrace 280 PFAS Solid-Phase Extraction Instrument is a high-throughput solid-phase extraction (SPE) device.


Avantor Inc. (Avantor), a company in the healthcare industry, manufactures and distributes chemicals, reagents, and lab supplies. The company's product line includes amino acids, silicones, bioreagents, denaturants, gas, solvents, stains, colours, and minerals. Education, lab and production, sourcing and procurement, services for lab equipment, commercial kitting, and downstream optimisation are just a few of the services offered by Avantor. It also provides laboratory services. The company increased the range of products it offers under its portfolio of brands, which also includes the names of VWR, Nusil, J.T. Baker, Macron specialised chemicals, and Poch. Taiwan, Mexico, the Netherlands, Poland, India, Malaysia, and South Korea are among the countries where the company maintains offices. The corporate headquarters of Avantor are located in Radnor, Pennsylvania, in the US. In November 2017, Avantor acquired VWR Corporation, an independent supplier of products, supply chain services, and customer support for lab and production clients.


Key Companies in the Solid Phase Extraction market include



  • Thermo Fisher Scientific

  • PerkinElmer Inc.

  • 3M

  • Gilson Incorporated

  • Gerstel GmbH & Co. KG

  • Merck KGaA

  • Agilent Technologies

  • GL Sciences Inc.

  • Biotage AB

  • Waters Corporation

  • Tecan Trading AG

  • Cytiva

  • Pall Corporation

  • Phenomenex Inc.

  • Sigma-Aldrich


Solid Phase Extraction Industry Developments


December 2022 A pioneer in automated sample preparation systems, Fluid Management Systems (FMS), and Agilent Technologies have partnered to develop and market workflows for the testing and analysis of POPs, such as PFAS, Dioxins, PCBs, and other emerging contaminants in environmental and food matrices.


Solid Phase Extraction Market Segmentation


Solid Phase Extraction Type Outlook



  • SPE Disk

  • SPE Cartridge

  • Others


Solid Phase Extraction Application Outlook



  • Pharmaceutical Industries

  • Academic & Research Institutes

  • Environmental

  • Hospitals & Clinics

  • Others


Solid Phase Extraction Regional Outlook



  • North America

    • US

    • Canada



  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe



  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific



  • Rest of the World

    • Middle East

    • Africa

    • Latin America



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