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    Postoperative Nausea Vomiting Market

    ID: MRFR/HC/41643-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    Postoperative Nausea and Vomiting Market Research Report By Type of Treatment (Pharmacological Treatment, Non-Pharmacological Treatment, Combination Therapy), By Medication Class (5-HT3 Antagonists, Dopamine Antagonists, Antihistamines, Corticosteroids), By Administration Route (Oral, Intravenous, Rectal), By Patient Demographics (Pediatric Patients, Adult Patients, Geriatric Patients) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Postoperative Nausea Vomiting Market Summary

    The Global Postoperative Nausea and Vomiting Market is projected to grow from 4.25 USD Billion in 2024 to 6.5 USD Billion by 2035.

    Key Market Trends & Highlights

    Postoperative Nausea and Vomiting Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 3.94% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 6.5 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 4.25 USD Billion, reflecting the current demand for effective postoperative care solutions.
    • Growing adoption of advanced antiemetic therapies due to increasing awareness of postoperative complications is a major market driver.

    Market Size & Forecast

    2024 Market Size 4.25 (USD Billion)
    2035 Market Size 6.5 (USD Billion)
    CAGR (2025-2035) 3.94%

    Major Players

    Mylan, Amgen, Johnson and Johnson, Merck, Pfizer, Teva Pharmaceutical Industries, GlaxoSmithKline, Bristol Myers Squibb, Hikma Pharmaceuticals, AbbVie, Novartis, Sanofi, Roche, AstraZeneca, Eli Lilly

    Postoperative Nausea Vomiting Market Trends

    The Global Postoperative Nausea and Vomiting Market is shaped by various significant drivers that influence its growth. One notable driver is the increasing number of surgical procedures performed globally, which boosts the demand for effective antiemetic treatments. As the healthcare industry advances, there is also a growing focus on patient comfort during and after surgeries, prompting healthcare providers to seek better solutions for managing postoperative nausea and vomiting. Additionally, the rise in awareness about the effects of postoperative nausea on recovery times encourages both physicians and patients to prioritize the management of this condition, further driving market growth.

    Opportunities abound in this market for innovation and the development of new therapies. Manufacturers can explore targeted drug delivery systems to improve the efficacy and reduce side effects of antiemetics. There is also potential for integrating digital health solutions, like mobile applications, which can help patients manage symptoms post-surgery more effectively.

    Furthermore, collaborations between pharmaceutical companies and healthcare providers can lead to new treatment protocols that enhance patient care. As the demand for personalized medicine continues to rise, tailored antiemetic therapies that account for individual patient profiles could present new avenues for growth. Recent trends indicate a shift towards non-pharmaceutical methods for alleviating postoperative nausea and vomiting. Techniques such as acupuncture, acupressure, and behavioral therapies are gaining traction as complementary options to traditional medications. This holistic approach aligns with the growing trend of patient-centered care, wherein patients prefer to have multiple options to manage their symptoms.

    Additionally, advancements in research are paving the way fora  better understanding of the underlying mechanisms of nausea and vomiting, potentially leading to the development of more effective treatments. Overall, the Global Postoperative Nausea and Vomiting Market is evolving with a focus on innovation, patient comfort, and an array of treatment modalities aimed at improving surgical outcomes.

    The increasing focus on patient safety and comfort in surgical procedures appears to be driving innovations in the management of postoperative nausea and vomiting, suggesting a shift towards more effective therapeutic options.

    U.S. Food and Drug Administration (FDA)

    Postoperative Nausea Vomiting Market Drivers

    Market Growth Charts

    Rising Surgical Procedures

    The increasing number of surgical procedures globally is a primary driver of the Global Postoperative Nausea and Vomiting Market Industry. As surgical techniques advance and become more accessible, the volume of surgeries performed continues to rise. For instance, the World Health Organization indicates that millions of surgeries are conducted annually, with a notable increase in elective procedures. This surge in surgical interventions correlates with a higher incidence of postoperative nausea and vomiting, necessitating effective management strategies. Consequently, the market is projected to grow from 4.25 USD Billion in 2024 to 6.5 USD Billion by 2035, reflecting a growing demand for antiemetic therapies.

    Increased Awareness and Education

    Heightened awareness and education regarding postoperative nausea and vomiting are driving growth in the Global Postoperative Nausea and Vomiting Market Industry. Healthcare professionals are increasingly recognizing the importance of managing these symptoms to enhance patient recovery and satisfaction. Educational initiatives and guidelines from health organizations emphasize the need for effective antiemetic protocols. This shift in focus is likely to lead to improved patient outcomes and a greater demand for antiemetic medications. As awareness continues to rise, the market is expected to expand, reflecting the growing recognition of postoperative nausea and vomiting as a critical aspect of surgical care.

    Advancements in Antiemetic Therapies

    Innovations in antiemetic therapies are significantly influencing the Global Postoperative Nausea and Vomiting Market Industry. New drug formulations and delivery methods are being developed to enhance efficacy and reduce side effects. For example, the introduction of long-acting formulations allows for better management of nausea and vomiting in postoperative patients. These advancements not only improve patient outcomes but also contribute to the overall growth of the market. The anticipated compound annual growth rate of 3.94% from 2025 to 2035 underscores the potential for these new therapies to capture market share and address the unmet needs of patients experiencing postoperative complications.

    Regulatory Support for Antiemetic Drugs

    Regulatory support for the development and approval of antiemetic drugs plays a crucial role in shaping the Global Postoperative Nausea and Vomiting Market Industry. Regulatory agencies are increasingly prioritizing the review and approval of new antiemetic therapies, recognizing their importance in improving patient care. This support facilitates faster access to innovative treatments, which can significantly impact patient recovery times and overall satisfaction. As more antiemetic drugs receive approval, the market is likely to experience growth, driven by the availability of effective treatment options for postoperative nausea and vomiting.

    Emerging Markets and Demographic Changes

    Emerging markets and demographic changes are contributing to the expansion of the Global Postoperative Nausea and Vomiting Market Industry. As populations in developing regions grow and age, the demand for surgical procedures is expected to increase. Additionally, the rising prevalence of chronic diseases necessitates more surgical interventions, further driving the need for effective management of postoperative nausea and vomiting. This trend is particularly evident in regions such as Asia-Pacific and Latin America, where healthcare infrastructure is improving. The market's growth in these areas is indicative of the broader global trend towards enhanced surgical care and patient management.

    Market Segment Insights

    Postoperative Nausea and Vomiting Market Type of Treatment Insights

    The Global Postoperative Nausea and Vomiting Market is increasingly focused on various types of treatment strategies to manage this common and distressing condition faced by patients following surgical procedures. In 2024, the market is expected to be valued at 4.25 USD Billion, demonstrating the growing emphasis on effective treatment methodologies that enhance patient recovery and comfort.

    Within the 'Type of Treatment' segment, the market can be divided primarily into three categories: Pharmacological Treatment, Non-Pharmacological Treatment, and Combination Therapy, each playing a vital role in addressing postoperative nausea and vomiting.Among these, Pharmacological Treatment holds the majority, valued at 2.1 USD Billion in 2024 and expected to rise to 3.2 USD Billion by 2035. 

    This dominance is largely due to the wide acceptance and efficacy of antiemetic drugs that help to mitigate nausea and vomiting, making them an integral part of postoperative care protocols around the world. Non-Pharmacological Treatment, valued at 1.3 USD Billion in 2024 and projected to increase to 1.7 USD Billion in 2035, provides significant alternative strategies that focus on behavioral and physical approaches, such as acupuncture and relaxation techniques, complementing pharmacological methods.The importance of Non-Pharmacological Treatment is underscored by its ability to not only alleviate symptoms but also cater to patients who may have contraindications for certain medications. 

    Lastly, Combination Therapy, valued at 0.85 USD Billion in 2024 and expected to see significant growth to 1.6 USD Billion by 2035, indicates a strategic trend towards more advanced and tailored treatment plans that integrate both pharmacological and non-pharmacological options. The rise in Combination Therapy reflects a growing body of evidence that emphasizes the effectiveness of multimodal approaches in enhancing patient outcomes and reducing the incidence of postoperative nausea and vomiting.

    The diversification in treatment types presents numerous opportunities for innovation and improvement in patient care, aligning with emerging trends in the Global Postoperative Nausea and Vomiting Market revenue, which show a clear intent toward holistic management strategies. As healthcare providers continue to refine their approaches, understanding the nuances in the Global Postoperative Nausea and Vomiting Market segmentation will be critical for developing effective treatment pathways that address individual patient needs.

    Postoperative Nausea and Vomiting Market Medication Class Insights

    This segment is characterized by a variety of medication types, with 5-HT3 antagonists playing a significant role due to their effectiveness in managing nausea, thus dominating the market because of their widespread use in clinical settings. Dopamine antagonists also contribute notably, addressing nausea linked to surgery and sedation, proving essential in postoperative care.Antihistamines and corticosteroids are important as well; antihistamines offer auxiliary support in reducing motion sickness-related nausea, while corticosteroids are used for their anti-inflammatory properties that help mitigate severe nausea and vomiting.

    Overall, the market segmentation reflects a blend of efficacy and diversified treatment approaches, highlighting the increasing demand for effective solutions in the Global Postoperative Nausea and Vomiting Market industry.

    Factors such as rising surgical procedures and improvements in medication efficacy are expected to further bolster the market, although challenges such as adverse effects and patient-specific responses remain prevalent, influencing the landscape of Global Postoperative Nausea and Vomiting Market data and statistics.

    Postoperative Nausea and Vomiting Market Administration Route Insights

    This segment consists of several methods, including Oral, Intravenous, and Rectal, each playing a crucial role in patient recovery. The Oral administration route is widely used due to its convenience and patient compliance, while Intravenous administration is essential for rapid effectiveness, particularly in surgical settings. Rectal administration serves as a valuable alternative, especially when patients are unable to take medications orally.Overall, these methods enhance the effectiveness of treatment, addressing the prevalence of postoperative nausea and vomiting. With increasing surgical procedures globally and a better understanding of nausea management, the significance of this market segment is projected to amplify.

    The growth of the Global Postoperative Nausea and Vomiting Market revenue reflects its evolving dynamics where market statistics indicate that the demand for effective and patient-friendly administration routes continues to rise. As healthcare providers seek innovative solutions for postoperative care, this segment is set to gain traction, offering various options tailored to patient needs.

    Postoperative Nausea and Vomiting Market Patient Demographics Insights

    The Global Postoperative Nausea and Vomiting Market is seeing considerable growth with progressive trends driven by an increasing surgical population and advances in antiemetic therapies. In exploring Patient Demographics, the market is notably segmented into Pediatric, Adult, and Geriatric Patients, each presenting unique needs and challenges. Pediatric Patients are essential in this sector due to their growing numbers in surgical procedures, requiring specialized care to manage their unique responses to anesthesia and surgery. Adult Patients dominate this market segment as they encompass a wide range of surgical experiences, particularly amidst the rising trends of elective surgeries.

    Meanwhile, Geriatric Patients represent an increasingly significant demographic given their susceptibility to postoperative complications, underscoring the necessity for tailored nausea and vomiting management. The interplay between these demographics indicates a multifaceted landscape with varying requirements, positioning the market for sustained growth across all segments as healthcare systems adapt to meet these diverse needs.Expanding knowledge around these patient categories will further drive the evolution of the Global Postoperative Nausea and Vomiting Market revenue through improved treatment protocols and patient safety measures.

    Get more detailed insights about Postoperative Nausea And Vomiting Market Research Report — Global Forecast till 2035

    Regional Insights

    The Global Postoperative Nausea and Vomiting Market revenue is projected to achieve notable growth across regional segments, with North America dominating the market due to its substantial valuation of 1.75 USD Billion in 2024, expected to rise to 2.75 USD Billion in 2035. Europe follows, holding a significant position valued at 1.00 USD Billion in 2024 and anticipated to reach 1.50 USD Billion by 2035. The APAC region exhibits a growing opportunity, starting at 1.10 USD Billion in 2024 and expanding to 1.70 USD Billion in 2035.

    South America and MEA are smaller segments, valued at 0.25 USD Billion and 0.15 USD Billion in 2024, respectively, with steady growth projected to 0.40 USD Billion and 0.20 USD Billion by 2035.The diversity in regional growth figures reflects varying healthcare advancements, regulatory environments, and patient population needs, with North America's majority holding demonstrating robust demand for effective postoperative treatments. Against rising awareness and healthcare investment, the growth drivers and market trends are shaping the landscape of the Global Postoperative Nausea and Vomiting Market statistics, underscoring the need for tailored solutions across different regions.

    Postoperative Nausea And Vomiting Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Postoperative Nausea and Vomiting Market is characterized by a dynamic landscape driven by the increasing prevalence of surgical procedures and the consequent demand for effective management solutions for postoperative nausea and vomiting. As healthcare providers emphasize patient safety and recovery, companies within this market are focusing on innovative drug formulations, delivery methods, and a better understanding of patient needs. The competitive environment is marked by several key players striving to improve their product offerings, enhance clinical efficacy, and expand their market reach through strategic collaborations, mergers, and acquisitions.

    The presence of generic alternatives alongside branded pharmaceuticals is further shaping pricing strategies and market dynamics, making it a critical area for continuous research and development.Mylan has established a significant presence in the Global Postoperative Nausea and Vomiting Market with its commitment to providing high-quality and affordable treatment options. 

    The company is known for its extensive portfolio, which includes various formulations aimed at effectively addressing postoperative nausea and vomiting. Mylan's strengths lie in its robust supply chain capabilities and the ability to swiftly respond to market demands with the introduction of generic alternatives that are both cost-effective and accessible to a broader patient population. This agility positions Mylan favorably within the competitive market landscape, allowing it to cater to the needs of healthcare providers while maintaining a strong focus on patient outcomes.

    Mylan’s dedication to research and development also enhances its competitive edge as it continues to explore new therapeutic approaches and partnerships to expand its offerings within this segment.Amgen plays a crucial role in the Global Postoperative Nausea and Vomiting Market by leveraging its extensive research capabilities and innovative treatment modalities. 

    The company is recognized for its pioneering efforts in biopharmaceuticals, which enhance the management of postoperative complications, including nausea and vomiting. Amgen's strengths include its strong pipeline of products that target these specific conditions through advanced mechanisms of action. The company also engages in extensive clinical trials aimed at validating its therapeutic options, thereby reinforcing its reputation for delivering products that are not only effective but also safe for patients undergoing surgical procedures.

    Furthermore, Amgen's commitment to patient education and support reinforces its market positioning, as it strives to improve overall patient experiences and outcomes in postoperative settings, making it a significant player in this competitive landscape.

    Key Companies in the Postoperative Nausea Vomiting Market market include

    Industry Developments

    • Q2 2024: FDA Approves Acacia Pharma’s BARHEMSYS® (amisulpride injection) for the Prevention and Treatment of Postoperative Nausea and Vomiting in Adults The FDA granted approval to Acacia Pharma’s BARHEMSYS® (amisulpride injection) for use in adults to prevent and treat postoperative nausea and vomiting (PONV), expanding therapeutic options for surgical patients.
    • Q1 2024: Acacia Pharma Announces U.S. Commercial Launch of BARHEMSYS® (amisulpride injection) for Postoperative Nausea and Vomiting Acacia Pharma announced the commercial launch of BARHEMSYS® in the United States, making the newly approved antiemetic available to hospitals and surgical centers for the management of PONV.
    • Q2 2024: FDA Approves Heron Therapeutics’ ZYNRELEF® for Expanded Indication Including Postoperative Nausea and Vomiting Heron Therapeutics received FDA approval for an expanded indication of ZYNRELEF®, now including the management of postoperative nausea and vomiting in addition to pain control.
    • Q1 2024: Heron Therapeutics Announces U.S. Launch of ZYNRELEF® for Postoperative Nausea and Vomiting Heron Therapeutics launched ZYNRELEF® in the U.S. market for the management of postoperative nausea and vomiting, following its recent FDA approval for this indication.
    • Q2 2024: Acacia Pharma and Hikma Pharmaceuticals Enter U.S. Co-Promotion Agreement for BARHEMSYS® Acacia Pharma and Hikma Pharmaceuticals announced a co-promotion agreement to expand the reach of BARHEMSYS® for postoperative nausea and vomiting in the U.S. hospital market.
    • Q1 2024: Acacia Pharma acquired by Eagle Pharmaceuticals in $103 million deal Eagle Pharmaceuticals completed the acquisition of Acacia Pharma, gaining rights to BARHEMSYS® and BYFAVO®, both used in the management of postoperative symptoms including nausea and vomiting.
    • Q2 2024: Fresenius Kabi Launches Ondansetron Injection USP in the United States Fresenius Kabi announced the U.S. launch of its generic Ondansetron Injection USP, an antiemetic indicated for the prevention of postoperative nausea and vomiting.
    • Q1 2024: GSK Receives European Commission Approval for IV Granisetron for Postoperative Nausea and Vomiting GlaxoSmithKline received European Commission approval for its intravenous granisetron formulation, expanding its use for the prevention and treatment of postoperative nausea and vomiting in adult and pediatric patients.
    • Q2 2024: Dr. Reddy’s Laboratories Launches Generic Granisetron Injection in the U.S. Market Dr. Reddy’s Laboratories announced the launch of its generic granisetron injection in the United States, indicated for the prevention of postoperative nausea and vomiting.
    • Q1 2024: Pfizer Launches New Formulation of ALOXI® (palonosetron hydrochloride) Injection for Postoperative Nausea and Vomiting Pfizer announced the launch of a new formulation of ALOXI® injection, designed for the prevention of postoperative nausea and vomiting in adult patients.
    • Q2 2024: Eagle Pharmaceuticals receives FDA approval for new BYFAVO® formulation for procedural sedation and PONV Eagle Pharmaceuticals received FDA approval for a new formulation of BYFAVO®, which is indicated for procedural sedation and the management of postoperative nausea and vomiting.
    • Q1 2024: Sandoz Launches Generic Dexamethasone Injection for Postoperative Nausea and Vomiting in the U.S. Sandoz announced the launch of its generic dexamethasone injection in the United States, indicated for the prevention and treatment of postoperative nausea and vomiting.

    Future Outlook

    Postoperative Nausea Vomiting Market Future Outlook

    The Global Postoperative Nausea and Vomiting Market is projected to grow at a 3.94% CAGR from 2024 to 2035, driven by advancements in antiemetic therapies and increasing surgical procedures.

    New opportunities lie in:

    • Invest in developing novel antiemetic drugs targeting specific patient demographics.
    • Enhance patient monitoring technologies to reduce postoperative complications.
    • Expand telehealth services for postoperative care management and follow-up.

    By 2035, the market is expected to demonstrate robust growth, reflecting evolving healthcare needs and innovative treatment solutions.

    Market Segmentation

    Postoperative Nausea and Vomiting Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Postoperative Nausea and Vomiting Market Medication Class Outlook

    • 5-HT3 Antagonists
    • Dopamine Antagonists
    • Antihistamines
    • Corticosteroids

    Postoperative Nausea and Vomiting Market Type of Treatment Outlook

    • Pharmacological Treatment
    • Non-Pharmacological Treatment
    • Combination Therapy

    Postoperative Nausea and Vomiting Market Administration Route Outlook

    • Oral
    • Intravenous
    • Rectal

    Postoperative Nausea and Vomiting Market Patient Demographics Outlook

    • Pediatric Patients
    • Adult Patients
    • Geriatric Patients

    Report Scope

     

    Attribute/Metric Source: Details
    MARKET SIZE 2023 4.09(USD Billion)
    MARKET SIZE 2024 4.25(USD Billion)
    MARKET SIZE 2035 6.5(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 3.94% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2023
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Mylan, Amgen, Johnson and Johnson, Merck, Pfizer, Teva Pharmaceutical Industries, GlaxoSmithKline, Bristol Myers Squibb, Hikma Pharmaceuticals, AbbVie, Novartis, Sanofi, Roche, AstraZeneca, Eli Lilly
    SEGMENTS COVERED Type of Treatment, Medication Class, Administration Route, Patient Demographics, Regional
    KEY MARKET OPPORTUNITIES Rising surgical procedures demand, Advanced antiemetic drug development, Growing awareness of PONV management, Integration of digital health solutions, Expansion in emerging markets
    KEY MARKET DYNAMICS Increasing surgical procedures, Growing geriatric population, Advanced antiemetic drugs, Rising patient awareness, Expanding healthcare infrastructure
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

    FAQs

    What is the expected market size of the Global Postoperative Nausea and Vomiting Market in 2024?

    The Global Postoperative Nausea and Vomiting Market is expected to be valued at 4.25 billion USD in 2024.

    What will be the market size of the Global Postoperative Nausea and Vomiting Market by 2035?

    By 2035, the market size is projected to reach 6.5 billion USD.

    What is the expected compound annual growth rate (CAGR) for the Global Postoperative Nausea and Vomiting Market from 2025 to 2035?

    The expected CAGR for the market from 2025 to 2035 is 3.94%.

    Which region is expected to dominate the Global Postoperative Nausea and Vomiting Market by 2024?

    North America is expected to hold the largest share of the market, valued at 1.75 billion USD in 2024.

    How much is the market for Pharmacological Treatment projected to grow by 2035?

    The market for Pharmacological Treatment is projected to grow from 2.1 billion USD in 2024 to 3.2 billion USD by 2035.

    What will be the market size for Non-Pharmacological Treatment by 2035?

    The market size for Non-Pharmacological Treatment is expected to reach 1.7 billion USD by 2035.

    Which companies are considered major players in the Global Postoperative Nausea and Vomiting Market?

    Major players include Mylan, Johnson and Johnson, Pfizer, and Merck.

    What is the expected market value of Combination Therapy in 2035?

    The market value for Combination Therapy is expected to increase to 1.6 billion USD by 2035.

    What is the market size for the Asia-Pacific region in 2024?

    The Asia-Pacific region's market size is expected to be 1.1 billion USD in 2024.

    What are the market growth expectations for the South America region by 2035?

    By 2035, the South American market size is projected to grow to 0.4 billion USD.

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