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Orphan Drugs Companies

Orphan drugs companies focus on the research, development, and manufacturing of pharmaceutical products designed to treat rare and orphan diseases. These companies play a crucial role in addressing unmet medical needs for patients with rare conditions, often providing life-saving or life-improving treatments.

Orphan Drugs Key Companies*Disclaimer: List of key companies in no particular orderLatest Orphan drugs Companies Update



  • Feb 2023: On Friday, Sun Pharmaceutical Industries announced that the U.S. health agency had given its company permission to distribute a generic drug used to treat multiple myeloma. According to a statement from Sun Pharma, the U.S. Food and Drug Administration has given the business final approval for the generic lenalidomide capsules in various dosages. Sun Pharma and Celgene Corporation reached a deal in June 2021 to end the patent litigation pertaining to Sun Pharma's generic lenalidomide capsules. As part of the settlement agreement, Celgene licensed Sun Pharma the patents needed to produce and market specific, restricted amounts of generic lenalidomide capsules in the United States starting in March 2022.




  • Oct 2023: On Friday, Sun Pharmaceutical Industries announced that the U.S. health agency had given its company permission to distribute a generic drug used to treat multiple myeloma. According to a statement from Sun Pharma, the U.S. Food and Drug Administration has given the business final approval for the generic lenalidomide capsules in various dosages. Sun Pharma and Celgene Corporation reached a deal in June 2021 to end the patent litigation pertaining to Sun Pharma's generic lenalidomide capsules. As part of the settlement agreement, Celgene licensed Sun Pharma the patents needed to produce and market specific, restricted amounts of generic lenalidomide capsules in the United States starting in March 2022. Furthermore, about 800 patients were enrolled in INSPIRE, an observational trial that is still underway and aims to determine the safety and efficacy of Alofisel in patients with complex CPF.


List of Orphan drugs Key companies in the market


  • F. Hoffmann-La Roche AG (Switzerland)




  • Mylan (US)




  • Celgene Corporation (US)




  • Novartis AG (Switzerland)




  • Biogen (US)




  • Takeda Pharmaceutical Company Limited (Japan)




  • Merck KGaA (Germany)




  • Eli Lilly And Company (US)




  • Sanofi (France)




  • Janssen Services LLC (US)



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