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Non Injectable Insulin Market

ID: MRFR/HC/33136-HCR
100 Pages
Rahul Gotadki
October 2025

Non-injection Insulin Market Research Report By Product Type (Insulin Patches, Insulin Inhalers, Insulin Pens, Insulin Gels), By Therapeutic Area (Type 1 Diabetes, Type 2 Diabetes, Gestational Diabetes), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), By End User (Hospitals, Home Care Settings, Diabetes Clinics) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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Non Injectable Insulin Market Summary

As per MRFR analysis, the Non-injection Insulin Market Size was estimated at 8.496 USD Billion in 2024. The Non-injection Insulin industry is projected to grow from 8.978 USD Billion in 2025 to 15.59 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.67 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Non-injection Insulin Market is poised for substantial growth driven by technological advancements and increasing patient demand for convenience.

  • North America remains the largest market for non-injection insulin, driven by high diabetes prevalence and advanced healthcare infrastructure.
  • The Asia-Pacific region is emerging as the fastest-growing market, fueled by rising awareness and increasing healthcare access.
  • Insulin pens dominate the market as the largest segment, while insulin patches are rapidly gaining traction as the fastest-growing segment.
  • Technological innovations in non-injection insulin delivery and the rising prevalence of diabetes are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 8.496 (USD Billion)
2035 Market Size 15.59 (USD Billion)
CAGR (2025 - 2035) 5.67%

Major Players

Novo Nordisk (DK), Sanofi (FR), Boehringer Ingelheim (DE), MannKind Corporation (US), Eli Lilly and Company (US), AstraZeneca (GB), Roche (CH), Pfizer (US), Bristol-Myers Squibb (US)

Non Injectable Insulin Market Trends

The Non-injection Insulin Market is currently experiencing a notable transformation, driven by advancements in technology and a growing demand for patient-friendly treatment options. As healthcare providers and patients alike seek alternatives to traditional injection methods, the market is witnessing an increase in the development and adoption of non-invasive insulin delivery systems. These innovations not only aim to enhance patient compliance but also strive to improve overall management of diabetes, which is becoming increasingly prevalent worldwide. Furthermore, the integration of digital health solutions, such as mobile applications and telemedicine, appears to be playing a crucial role in facilitating better monitoring and management of insulin therapy, thereby contributing to the market's expansion. In addition to technological advancements, the Non-injection Insulin Market is also influenced by changing consumer preferences and a heightened awareness of diabetes management. Patients are increasingly seeking options that minimize discomfort and enhance convenience, which has led to a rise in the popularity of inhalable and oral insulin formulations. This shift in consumer behavior suggests a potential for sustained growth in the market, as manufacturers continue to innovate and respond to the evolving needs of patients. Overall, the Non-injection Insulin Market seems poised for further development, with a focus on improving patient outcomes and enhancing the quality of life for individuals living with diabetes.

Technological Advancements in Delivery Systems

Recent innovations in non-invasive insulin delivery systems are reshaping the Non-injection Insulin Market. These advancements include inhalable and oral formulations that aim to provide effective alternatives to traditional injections. As technology progresses, the efficiency and reliability of these delivery methods are expected to improve, potentially leading to increased adoption among patients.

Growing Patient Demand for Convenience

There is a noticeable shift in patient preferences towards more convenient and less invasive treatment options. This trend is driving the development of non-injection insulin products that cater to the desire for ease of use. As patients prioritize comfort and convenience, manufacturers are likely to focus on creating solutions that align with these expectations.

Integration of Digital Health Solutions

The incorporation of digital health technologies into diabetes management is becoming increasingly prevalent. Mobile applications and telehealth services are enhancing patient engagement and monitoring, which may lead to better adherence to non-injection insulin therapies. This trend suggests a synergistic relationship between technology and treatment, potentially benefiting the overall Non-injection Insulin Market.

Non Injectable Insulin Market Drivers

Rising Prevalence of Diabetes

The increasing prevalence of diabetes worldwide is a critical driver for the Non-injection Insulin Market. With the International Diabetes Federation reporting that approximately 537 million adults are living with diabetes, the demand for alternative insulin delivery methods is escalating. Non-injection options are particularly appealing to those who are averse to needles, thus broadening the patient base. This growing population of diabetic patients is expected to drive the market, as more individuals seek convenient and less painful methods of insulin administration. The Non-injection Insulin Market is poised for growth as healthcare providers look for effective solutions to manage this chronic condition.

Patient-Centric Healthcare Trends

The Non-injection Insulin Market is increasingly influenced by patient-centric healthcare trends that prioritize comfort and convenience. Patients are actively seeking alternatives to traditional injection methods, which can be painful and inconvenient. This shift in consumer preference is prompting manufacturers to innovate and develop non-injection insulin solutions that align with patient needs. Market Research Future indicates that products designed with user experience in mind are more likely to gain traction among consumers. As healthcare systems evolve to focus on patient satisfaction, the Non-injection Insulin Market is expected to expand, driven by the demand for more user-friendly insulin delivery options.

Regulatory Support for Innovative Therapies

Regulatory bodies are increasingly supportive of innovative therapies in the Non-injection Insulin Market, which is likely to facilitate market growth. Streamlined approval processes for new delivery systems and formulations can accelerate the introduction of non-injection insulin products. For instance, recent initiatives aimed at expediting the review of diabetes management technologies suggest a favorable environment for innovation. This regulatory support not only encourages investment in research and development but also instills confidence among manufacturers. As a result, the Non-injection Insulin Market may see a rise in the number of new products entering the market, catering to diverse patient needs.

Integration of Health Technology and Wearable Devices

The integration of health technology and wearable devices is emerging as a significant driver in the Non-injection Insulin Market. Wearable devices that monitor glucose levels and provide real-time data can enhance the management of diabetes, making non-injection insulin options more appealing. The convergence of technology and healthcare is likely to lead to the development of smart insulin delivery systems that can automatically adjust dosages based on real-time glucose readings. This trend not only improves patient outcomes but also positions the Non-injection Insulin Market at the forefront of diabetes management solutions, potentially attracting a broader audience.

Technological Innovations in Non-injection Insulin Delivery

The Non-injection Insulin Market is experiencing a surge in technological innovations that enhance the delivery of insulin. Devices such as inhalers and transdermal patches are being developed, which could potentially improve patient compliance and ease of use. According to recent estimates, the market for inhaled insulin alone is projected to reach USD 1.5 billion by 2026. These advancements not only promise to make insulin administration less invasive but also aim to provide more accurate dosing. As technology continues to evolve, the Non-injection Insulin Market is likely to witness a shift towards more sophisticated delivery systems that cater to the needs of patients, thereby expanding the market further.

Market Segment Insights

By Type: Insulin Pens (Largest) vs. Insulin Patches (Fastest-Growing)

In the Non-injection Insulin Market, insulin pens hold the largest market share due to their widespread adoption among patients. Their ease of use, accuracy, and convenience make them the preferred choice for many individuals who require insulin therapy. Meanwhile, insulin patches are gaining momentum and are considered the fastest-growing segment in this market, driven by the demand for less invasive delivery methods that offer greater comfort and discretion. Their innovative design is attracting attention from both patients and healthcare providers, contributing to their growth path.

Insulin Pens (Dominant) vs. Insulin Inhalers (Emerging)

In the Non-injection Insulin Market, insulin pens dominate due to their user-friendliness, precise dosing capabilities, and the ability to manage diabetes effectively. Patients appreciate their portability and the simplicity of pre-filled options, making them a first choice for many users. In contrast, insulin inhalers represent an emerging segment, offering a new mode of delivery that appeals especially to those seeking alternatives to needles. Though they are not yet as established as insulin pens, inhalers are growing in popularity, particularly among younger patients and those desiring a less conventional method of insulin administration.

By Therapeutic Area: Type 2 Diabetes (Largest) vs. Type 1 Diabetes (Fastest-Growing)

The Non-injection Insulin Market is primarily divided into three therapeutic areas: Type 1 Diabetes, Type 2 Diabetes, and Gestational Diabetes. Among these, Type 2 Diabetes holds the largest share, driven by the increasing prevalence of lifestyle-related factors such as obesity and sedentary habits. As a result, this segment continues to dominate the market, accounting for a significant portion of insulin therapy prescriptions. Meanwhile, Type 1 Diabetes, though smaller in market share, is witnessing rapid growth fueled by advancements in insulin formulations and rising awareness regarding diabetes management among younger populations. Growth trends for Type 2 Diabetes insulin therapy are largely attributed to an expanding patient base and the introduction of innovative non-injection delivery methods that enhance patient compliance. On the other hand, Type 1 Diabetes is showing the fastest growth, thanks to technological advancements and greater investment in research and development of new therapies. The market dynamics are positively influenced by increased healthcare expenditure and policy support aimed at improving diabetes care, creating significant opportunities in both segments.

Type 2 Diabetes (Dominant) vs. Type 1 Diabetes (Emerging)

Type 2 Diabetes represents the dominant segment in the Non-injection Insulin Market, characterized by a broad base of patients requiring ongoing management of their condition. This segment’s strength lies in its established therapeutic protocols and robust patient adherence to treatment regimens. Innovative non-injection solutions, such as inhalable insulins, are enhancing existing treatment options, making therapies more accessible. Conversely, Type 1 Diabetes, while emerging, is gaining momentum due to increased diagnostic rates and heightened awareness of early treatment needs. Newer formulations and delivery systems are tailored specifically for the Type 1 patient population, leading to rapid adoption and a promising outlook for future growth. Both segments are crucial in the evolving landscape of diabetes management.

By Distribution Channel: Retail Pharmacies (Largest) vs. Online Pharmacies (Fastest-Growing)

In the Non-injection Insulin Market, the distribution channels are characterized by varying shares, with retail pharmacies holding the largest market presence. This segment is well-established and has a strong customer base due to convenience and accessibility. In contrast, online pharmacies are gaining traction, appealing to consumers who favor digital solutions and home delivery services. Hospital pharmacies also play an important role, primarily serving patients directly within the healthcare system. Growth trends in this segment are influenced by several factors, including the shift towards e-commerce and the increasing adoption of chronic disease management programs that facilitate the distribution of non-injection insulin. Retail pharmacies benefit from their widespread presence, while online pharmacies are rapidly expanding due to technological advancements and the rising preference for online healthcare services. Hospital pharmacies continue to be essential for treatment continuity, although they tend to serve a more localized market.

Retail Pharmacies (Dominant) vs. Online Pharmacies (Emerging)

Retail pharmacies represent a dominant distribution channel in the Non-injection Insulin Market, offering consumers the ability to access medications conveniently. Their significant footfall and trusted relationships with healthcare providers enhance customer loyalty. These pharmacies typically provide a broad range of services beyond dispensing insulin, such as health consultations and chronic disease management programs. On the other hand, online pharmacies emerge as an innovative alternative, capturing a segment of consumers that prioritize convenience and contactless transactions. The rise of telehealth and secure delivery options is propelling the growth of online pharmacies, enabling them to reach a broader demographic, particularly tech-savvy younger patients and those in remote areas.

By End User: Hospitals (Largest) vs. Home Care Settings (Fastest-Growing)

In the Non-injection Insulin Market, hospitals remain the largest end user segment, commanding a significant share of the market. Their established infrastructure for patient care and robust diabetes management programs contribute to their dominance in insulin usage. Conversely, home care settings are emerging rapidly, especially as patients seek more autonomy in managing diabetes. The growing number of diabetes patients who prefer self-administration of insulin therapies is steering market dynamics, making home care settings a crucial player in this space.

End User: Hospitals (Dominant) vs. Home Care Settings (Emerging)

Hospitals play a dominant role in the Non-injection Insulin Market due to their comprehensive healthcare facilities, which provide direct access to insulin therapies for a wide range of patients. They offer a controlled environment for administering treatments and continuous monitoring, leading to better patient outcomes. On the other hand, home care settings are emerging as vital players, fueled by advancements in insulin delivery technologies and a shift toward patient-centered care. These settings allow patients to maintain their lifestyle while managing diabetes effectively, indicating a growing trend of convenience in insulin administration.

Get more detailed insights about Non Injectable Insulin Market

Regional Insights

North America : Market Leader in Innovation

North America is the largest market for non-injection insulin, holding approximately 45% of the global market share. The region's growth is driven by increasing diabetes prevalence, technological advancements, and supportive regulatory frameworks. The demand for non-invasive delivery methods is rising, fueled by patient preference for convenience and comfort. Regulatory bodies are also promoting innovative therapies, further catalyzing market expansion. The United States is the primary contributor to this market, with significant investments from key players like Eli Lilly and Company, Novo Nordisk, and Sanofi. The competitive landscape is characterized by a focus on research and development, leading to the introduction of novel products. Canada also plays a vital role, contributing to the overall market dynamics with its growing healthcare infrastructure and increasing awareness about diabetes management.

Europe : Emerging Market with Growth Potential

Europe is the second-largest market for non-injection insulin, accounting for approximately 30% of the global market share. The region's growth is propelled by rising diabetes cases, increasing healthcare expenditure, and favorable regulations that encourage innovation. The European Medicines Agency (EMA) has been instrumental in streamlining the approval process for new therapies, thus enhancing market accessibility and patient options. Leading countries in this region include Germany, France, and the UK, where major players like Sanofi and Boehringer Ingelheim are actively involved. The competitive landscape is marked by collaborations and partnerships aimed at developing advanced non-injection delivery systems. The presence of robust healthcare systems and a growing focus on patient-centric solutions further enhance the market's potential in Europe.

Asia-Pacific : Rapidly Growing Market Segment

Asia-Pacific is witnessing rapid growth in the non-injection insulin market, holding approximately 20% of the global market share. The region's expansion is driven by increasing diabetes prevalence, urbanization, and rising disposable incomes. Governments are implementing initiatives to improve healthcare access, which is further boosting demand for innovative diabetes management solutions. Regulatory bodies are also focusing on enhancing the approval processes for new therapies, fostering a conducive environment for market growth. Countries like China and India are at the forefront of this growth, with significant investments from key players such as Novo Nordisk and Eli Lilly. The competitive landscape is evolving, with local manufacturers emerging alongside established global players. The increasing awareness of diabetes management and the shift towards non-invasive delivery methods are shaping the market dynamics in this region.

Middle East and Africa : Untapped Market with Potential

The Middle East and Africa region is an emerging market for non-injection insulin, holding about 5% of the global market share. The growth is driven by rising diabetes prevalence, increasing healthcare investments, and a growing focus on chronic disease management. Governments are recognizing the need for improved healthcare infrastructure, which is catalyzing the demand for innovative diabetes solutions. Regulatory frameworks are gradually evolving to support new product introductions, enhancing market potential. Leading countries in this region include South Africa and the UAE, where there is a growing presence of key players like Roche and Pfizer. The competitive landscape is characterized by a mix of multinational corporations and local firms, focusing on expanding their product offerings. The increasing awareness of diabetes and the need for effective management solutions are driving market growth in the Middle East and Africa.

Non Injectable Insulin Market Regional Image

Key Players and Competitive Insights

The Non-injection Insulin Market is currently characterized by a dynamic competitive landscape, driven by increasing demand for innovative diabetes management solutions. Key players such as Novo Nordisk (DK), Sanofi (FR), and Eli Lilly and Company (US) are at the forefront, each adopting distinct strategies to enhance their market presence. Novo Nordisk (DK) focuses on innovation, particularly in developing oral insulin formulations, while Sanofi (FR) emphasizes strategic partnerships to expand its product offerings. Eli Lilly and Company (US) is actively pursuing digital transformation initiatives to improve patient engagement and adherence, thereby shaping a competitive environment that prioritizes patient-centric solutions.

In terms of business tactics, companies are increasingly localizing manufacturing to reduce costs and enhance supply chain efficiency. The Non-injection Insulin Market appears moderately fragmented, with several players vying for market share. The collective influence of these key players is significant, as they not only drive innovation but also set industry standards that smaller companies must follow to remain competitive.

In August 2025, Novo Nordisk (DK) announced a collaboration with a leading technology firm to develop a digital platform aimed at enhancing insulin delivery systems. This strategic move is likely to bolster Novo Nordisk's position in the market by integrating technology with its product offerings, thereby improving patient outcomes and adherence to treatment regimens. The collaboration underscores the importance of digital health solutions in the current market landscape.

In September 2025, Sanofi (FR) launched a new oral insulin product, which is expected to significantly impact the market by providing a non-injection alternative for patients. This product launch not only diversifies Sanofi's portfolio but also aligns with the growing trend of patient preference for less invasive treatment options. The introduction of this product may enhance Sanofi's competitive edge, particularly among patients seeking convenience and ease of use.

In October 2025, Eli Lilly and Company (US) unveiled a new initiative focused on sustainability in insulin production, aiming to reduce the carbon footprint of its manufacturing processes. This initiative reflects a broader industry trend towards sustainability and may resonate well with environmentally conscious consumers. By prioritizing sustainable practices, Eli Lilly is likely to strengthen its brand reputation and appeal to a growing segment of the market that values corporate responsibility.

As of October 2025, the Non-injection Insulin Market is witnessing trends such as digitalization, sustainability, and the integration of artificial intelligence in product development. Strategic alliances are increasingly shaping the competitive landscape, enabling companies to leverage each other's strengths. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition to a focus on innovation, technology integration, and supply chain reliability. This transition may redefine how companies position themselves in the market, emphasizing the importance of delivering value beyond just cost.

Key Companies in the Non Injectable Insulin Market market include

Industry Developments

Recent developments in the Non-injection Insulin Market highlight significant advancements and strategic movements among key companies. Novo Nordisk, a leading player, has been focusing on the innovation of non-injection delivery mechanisms, enhancing patient adherence and lifestyle integration.

Sanofi and Lilly are also poised to expand their portfolios in oral insulin formulations, responding to the growing demand for user-friendly diabetes management solutions.

The recent partnership between MannKind Corporation and a major pharmaceutical company aims to accelerate the development of inhaled insulin products, showcasing a collaborative effort towards innovative treatments. On the acquisition front, GSK has shown interest in acquiring technologies related to non-injection insulin to diversify its diabetes care offerings.

Market valuations for companies like AstraZeneca and Merck have been positively impacted by their investments in research and development of non-injection delivery systems, signaling a promising growth trajectory.

Additionally, the Diabetes Research Institute continues to lead initiatives focused on improving diabetes management through technological advancements. The momentum in this market indicates a strong commitment from providers to enhance patient experiences while providing effective insulin delivery alternatives.

Future Outlook

Non Injectable Insulin Market Future Outlook

The Non-injection Insulin Market is projected to grow at a 5.67% CAGR from 2024 to 2035, driven by technological advancements, increasing diabetes prevalence, and patient preference for non-invasive solutions.

New opportunities lie in:

  • Development of oral insulin formulations for enhanced patient compliance.
  • Investment in smart insulin delivery devices integrated with mobile health applications.
  • Expansion into emerging markets with tailored pricing strategies for affordability.

By 2035, the Non-injection Insulin Market is expected to achieve substantial growth and innovation.

Market Segmentation

Non Injectable Insulin Market Type Outlook

  • Insulin Patches
  • Insulin Inhalers
  • Insulin Pens
  • Insulin Gels

Non Injectable Insulin Market End User Outlook

  • Hospitals
  • Home Care Settings
  • Diabetes Clinics

Non Injectable Insulin Market Therapeutic Area Outlook

  • Type 1 Diabetes
  • Type 2 Diabetes
  • Gestational Diabetes

Non Injectable Insulin Market Distribution Channel Outlook

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Report Scope

MARKET SIZE 20248.496(USD Billion)
MARKET SIZE 20258.978(USD Billion)
MARKET SIZE 203515.59(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.67% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMarket analysis in progress
Segments CoveredMarket segmentation analysis in progress
Key Market OpportunitiesAdvancements in oral delivery systems enhance patient compliance in the Non-injection Insulin Market.
Key Market DynamicsRising demand for non-injection insulin products driven by technological advancements and changing consumer preferences.
Countries CoveredNorth America, Europe, APAC, South America, MEA

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FAQs

What is the projected market valuation of the Non-injection Insulin Market by 2035?

The Non-injection Insulin Market is projected to reach a valuation of 15.59 USD Billion by 2035.

What was the market valuation of the Non-injection Insulin Market in 2024?

In 2024, the Non-injection Insulin Market was valued at 8.496 USD Billion.

What is the expected CAGR for the Non-injection Insulin Market from 2025 to 2035?

The expected CAGR for the Non-injection Insulin Market during the forecast period 2025 - 2035 is 5.67%.

Which companies are considered key players in the Non-injection Insulin Market?

Key players in the Non-injection Insulin Market include Novo Nordisk, Sanofi, Boehringer Ingelheim, MannKind Corporation, Eli Lilly and Company, AstraZeneca, Roche, Pfizer, and Bristol-Myers Squibb.

What are the main segments of the Non-injection Insulin Market?

The main segments of the Non-injection Insulin Market include Insulin Patches, Insulin Inhalers, Insulin Pens, and Insulin Gels.

How does the market for Type 2 Diabetes compare to other therapeutic areas in the Non-injection Insulin Market?

The market for Type 2 Diabetes is projected to grow from 5.0 USD Billion in 2024 to 9.0 USD Billion by 2035, indicating substantial growth compared to other therapeutic areas.

What distribution channels are utilized in the Non-injection Insulin Market?

Distribution channels in the Non-injection Insulin Market include Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies.

What is the projected growth for Insulin Pens in the Non-injection Insulin Market?

The market for Insulin Pens is expected to grow from 3.0 USD Billion in 2024 to 5.5 USD Billion by 2035.

Which end-user segments are expected to drive growth in the Non-injection Insulin Market?

End-user segments such as Hospitals, Home Care Settings, and Diabetes Clinics are expected to drive growth in the Non-injection Insulin Market.

What is the anticipated market size for Insulin Inhalers by 2035?

The market size for Insulin Inhalers is anticipated to reach 3.5 USD Billion by 2035.

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