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L-Citrulline Market

ID: MRFR/CnM/0315-CR
97 Pages
Anshula Mandaokar
November 2018

L-Citrulline Market Research Report Information By Type (Power Type and Crystal Type), By Classification (Medical Grade and Food Grade), By Application (Cosmetic & Personal Care, Food & Beverages, Pharmaceuticals, Agriculture, Animal Feed and Other), and By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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L-Citrulline Market Infographic
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L-Citrulline Market Summary

As per MRFR analysis, the L-Citrulline Market Size was estimated at 0.13 USD Billion in 2024. The L-Citrulline industry is projected to grow from 0.1367 in 2025 to 0.2252 by 2035, exhibiting a compound annual growth rate (CAGR) of 5.12 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The L-Citrulline Market is experiencing robust growth driven by health awareness and athletic performance.

  • The demand for natural supplements continues to rise, particularly in North America, which remains the largest market for L-Citrulline Market.
  • Athletic performance enhancement is a key focus, contributing to the increasing popularity of L-Citrulline Market in the Asia-Pacific region, the fastest-growing market.
  • E-commerce platforms are expanding, facilitating greater access to L-Citrulline Market products across various consumer segments.
  • Market drivers such as growing awareness of health benefits and the rising popularity in sports nutrition are propelling the growth of both powder type and medical grade segments.

Market Size & Forecast

2024 Market Size 0.13 (USD Billion)
2035 Market Size 0.2252 (USD Billion)
CAGR (2025 - 2035) 5.12%

Major Players

Kyowa Hakko Bio Co., Ltd. (JP), Nutraceutical Corporation (US), Ginkgo BioWorks, Inc. (US), BASF SE (DE), Cargill, Incorporated (US), NutraBio Labs, Inc. (US), Hawthorn Pharmaceuticals, Inc. (US), Jarrow Formulas, Inc. (US), NOW Foods, Inc. (US)

L-Citrulline Market Trends

The L-Citrulline Market is currently experiencing notable growth, driven by increasing consumer awareness regarding health and wellness. This amino acid, primarily found in watermelon, is recognized for its potential benefits in enhancing athletic performance and improving cardiovascular health. As more individuals seek natural supplements to boost their physical capabilities, the demand for L-Citrulline Market is likely to rise. Additionally, the trend towards plant-based diets may further propel the market, as consumers look for natural sources of nutrients. Manufacturers are responding to this shift by developing innovative products that incorporate L-Citrulline Market, appealing to a broader audience. Moreover, the L-Citrulline Market is witnessing a surge in research and development activities. Scientific studies exploring the various health benefits of this compound are becoming more prevalent, which may lead to increased acceptance and usage among consumers. The growing popularity of fitness and wellness trends, coupled with the rise of e-commerce platforms, is facilitating easier access to L-Citrulline Market products. As a result, the market landscape is evolving, with new entrants and established players alike striving to capture consumer interest through diverse offerings and marketing strategies.

Rising Demand for Natural Supplements

The L-Citrulline Market is seeing a shift towards natural health products as consumers become more health-conscious. This trend indicates a preference for supplements derived from natural sources, which may enhance the appeal of L-Citrulline Market.

Increased Focus on Athletic Performance

There is a growing emphasis on fitness and athletic performance among consumers. This trend suggests that L-Citrulline Market may be increasingly recognized for its potential benefits in enhancing endurance and recovery, attracting athletes and fitness enthusiasts.

Expansion of E-commerce Platforms

The rise of online shopping is transforming the L-Citrulline Market. E-commerce platforms are providing consumers with greater access to a variety of L-Citrulline Market products, which may facilitate market growth and diversification.

L-Citrulline Market Drivers

Innovations in Product Formulations

The L-Citrulline Market is witnessing innovations in product formulations that cater to diverse consumer preferences. Manufacturers are increasingly developing L-Citrulline Market products in various forms, including powders, capsules, and ready-to-drink beverages. This diversification allows consumers to choose products that align with their lifestyles and consumption habits. Additionally, the incorporation of L-Citrulline Market into functional foods and beverages is becoming more prevalent, appealing to health-conscious consumers seeking convenient options. As product innovation continues to shape the market, it is anticipated that the availability of L-Citrulline Market in various formats will enhance its appeal and drive further growth in the industry.

Growing Awareness of Health Benefits

The L-Citrulline Market is experiencing a surge in consumer awareness regarding the health benefits associated with L-Citrulline Market supplementation. Research indicates that L-Citrulline Market may enhance nitric oxide production, which can lead to improved blood flow and cardiovascular health. As consumers become more health-conscious, they are increasingly seeking natural supplements that support overall wellness. This trend is reflected in the rising sales of L-Citrulline Market products, with the market projected to grow at a compound annual growth rate of approximately 8% over the next five years. The increasing prevalence of lifestyle-related health issues further propels the demand for effective dietary supplements, positioning L-Citrulline Market as a favorable option in the health and wellness sector.

Rising Popularity in Sports Nutrition

The L-Citrulline Market is significantly influenced by the growing popularity of sports nutrition products. Athletes and fitness enthusiasts are increasingly turning to L-Citrulline Market for its potential to enhance exercise performance and recovery. Studies suggest that L-Citrulline Market supplementation may reduce muscle soreness and improve endurance, making it a sought-after ingredient in pre-workout formulations. The sports nutrition segment is expected to account for a substantial share of the L-Citrulline Market, driven by the increasing participation in sports and fitness activities. As more individuals engage in regular physical activity, the demand for effective performance-enhancing supplements, including L-Citrulline Market, is likely to rise, further propelling market growth.

Increasing Adoption in Functional Foods

The L-Citrulline Market is experiencing an uptick in the adoption of L-Citrulline Market in functional foods. As consumers become more health-oriented, there is a growing interest in foods that offer additional health benefits beyond basic nutrition. L-Citrulline Market is being integrated into a variety of food products, including energy bars, smoothies, and fortified beverages, to enhance their nutritional profiles. This trend aligns with the broader movement towards functional foods that support health and wellness. The increasing incorporation of L-Citrulline Market into everyday food products is likely to expand its market reach, making it more accessible to a wider audience and contributing to the overall growth of the L-Citrulline Market.

Expansion of Dietary Supplement Industry

The L-Citrulline Market is benefiting from the overall expansion of the dietary supplement industry. With a growing number of consumers incorporating supplements into their daily routines, the demand for L-Citrulline Market is on the rise. The dietary supplement market has been valued at over 140 billion, with projections indicating continued growth as more individuals seek to improve their health and wellness through supplementation. This trend is particularly evident among older adults who are increasingly focused on maintaining vitality and physical performance. As the dietary supplement industry evolves, L-Citrulline Market is likely to gain traction as a key ingredient in various formulations, catering to a diverse consumer base.

Market Segment Insights

By Type: Powder Type (Largest) vs. Crystal Type (Fastest-Growing)

In the L-Citrulline Market, the Powder Type holds a significant portion of the market share, largely due to its versatility and ease of use in various applications, including dietary supplements and fitness products. This segment has established itself as a consumer favorite, appealing to both athletes seeking performance enhancement and health-conscious individuals looking to incorporate beneficial amino acids into their diets. Conversely, the Crystal Type, while currently smaller in market share, is gaining recognition for its purity and streamlined application in formulations, particularly in niche markets.

L-Citrulline Market: Powder Type (Dominant) vs. Crystal Type (Emerging)

The Powder Type of L-Citrulline Market is recognized as the dominant form in the market, characterized by its ease of dosage and flexibility across diverse applications. This segment appeals to a wide demographic, from athletes to casual consumers who seek health benefits. On the other hand, the Crystal Type is emerging as a significant competitor, touted for its high purity and concentration which make it desirable for specialized dietary formulations. While the Powder Type remains popular, the Crystal Type attracts a growing segment of health-conscious consumers and formulators who prioritize quality and efficacy, ultimately driving growth in this segment. As consumers become more informed, the demand for high-purity products is likely to increase, propelling the Crystal Type forward.

By Classification: Medical Grade (Largest) vs. Food Grade (Fastest-Growing)

The L-Citrulline Market is primarily segmented into Medical Grade and Food Grade classifications. The Medical Grade segment holds the largest share, driven by its popularity in therapeutic applications and performance enhancement, particularly among athletes and bodybuilders. On the other hand, the Food Grade segment has been gaining traction, reflecting increasing consumer awareness about the health benefits of L-Citrulline Market supplementation, especially in functional foods and beverages.

Classification: Medical Grade (Dominant) vs. Food Grade (Emerging)

Medical Grade L-Citrulline Market is recognized for its high purity and efficacy, making it a preferred choice in the healthcare sector for applications such as treating conditions related to vascular health and enhancing exercise performance. This segment tends to dominate the market due to stringent quality standards and significant demand from pharmaceutical companies. Conversely, the Food Grade segment is emerging rapidly, appealing to a health-conscious demographic seeking natural health supplements. It caters to the nutraceutical and food industry, focusing on product innovation and fortified foods. This growth is propelled by the trend of incorporating health supplements into everyday diets.

By Application: Cosmetic & Personal Care (Largest) vs. Food & Beverages (Fastest-Growing)

In the L-Citrulline Market, application segments present a dynamic distribution of share with Cosmetic & Personal Care holding the largest portion. This broad market is increasingly leveraging L-Citrulline Market for its efficacy in skin health and overall beauty solutions. Food & Beverages is rapidly gaining ground, driven by growing consumer interest in health and wellness, positioning it as a significant segment poised for expansion.

Cosmetic & Personal Care: Dominant vs. Food & Beverages: Emerging

The Cosmetic & Personal Care segment thrives on the demand for innovative skincare solutions, tapping into the rising trend of using natural ingredients and efficacy in anti-aging products. L-Citrulline Market is recognized for its moisturizing properties and ability to support skin hydration. In contrast, the Food & Beverages sector is emerging strongly, fueled by health-conscious consumers seeking functional foods and beverages enriched with amino acids like L-Citrulline Market. This segment's growth is further propelled by trends towards incorporating performance-enhancing natural compounds, reflecting a shift in modern dietary preferences.

Get more detailed insights about L-Citrulline Market

Regional Insights

North America : Market Leader in L-Citrulline Market

North America is the largest market for L-Citrulline Market, accounting for approximately 45% of the global share. The region's growth is driven by increasing health awareness, rising demand for dietary supplements, and a growing fitness culture. Regulatory support from agencies like the FDA further catalyzes market expansion, ensuring product safety and efficacy. The U.S. leads this market, followed closely by Canada, which holds about 15% of the market share. The competitive landscape in North America is robust, featuring key players such as Kyowa Hakko Bio Co., Ltd., Nutraceutical Corporation, and Ginkgo BioWorks, Inc. These companies are investing in research and development to innovate and enhance product offerings. The presence of established distribution channels and a strong consumer base for health supplements further solidifies North America's position as a market leader.

Europe : Emerging Market Potential

Europe is witnessing significant growth in the L-Citrulline Market, holding approximately 30% of the global share. The increasing prevalence of lifestyle diseases and a shift towards preventive healthcare are key drivers of demand. Regulatory frameworks, such as the European Food Safety Authority (EFSA) guidelines, support the safe use of dietary supplements, fostering market growth. Germany and the UK are the largest markets in this region, contributing significantly to the overall share. Leading countries in Europe include Germany, the UK, and France, with a competitive landscape featuring major players like BASF SE and Cargill, Incorporated. These companies are focusing on product innovation and strategic partnerships to enhance their market presence. The growing trend of fitness and wellness among consumers is further propelling the demand for L-Citrulline Market products across Europe.

Asia-Pacific : Rapid Growth and Innovation

Asia-Pacific is emerging as a significant player in the L-Citrulline Market, accounting for about 20% of the global share. The region's growth is fueled by rising disposable incomes, increasing health awareness, and a growing fitness culture. Countries like China and India are leading this growth, with supportive government initiatives promoting health and wellness. The demand for dietary supplements is on the rise, driven by a younger population seeking fitness solutions. China is the largest market in the region, followed by Japan and India. The competitive landscape is characterized by both local and international players, including NutraBio Labs, Inc. and Hawthorn Pharmaceuticals, Inc. These companies are focusing on product development and marketing strategies tailored to local preferences, enhancing their market presence in the region.

Middle East and Africa : Untapped Market Potential

The Middle East and Africa region is gradually emerging in the L-Citrulline Market, holding approximately 5% of the global share. The growth is driven by increasing health awareness and a rising trend towards fitness and wellness. Countries like South Africa and the UAE are leading this market, with growing interest in dietary supplements. Regulatory bodies are beginning to establish guidelines to ensure product safety, which is expected to further boost market growth. In this region, the competitive landscape is still developing, with a mix of local and international players. Companies are focusing on educating consumers about the benefits of L-Citrulline Market, which is crucial for market penetration. The potential for growth is significant, as more consumers become aware of health and wellness products, paving the way for future expansion.

L-Citrulline Market Regional Image

Key Players and Competitive Insights

The L-Citrulline Market is currently characterized by a dynamic competitive landscape, driven by increasing consumer awareness regarding health benefits and the growing demand for dietary supplements. Key players such as Kyowa Hakko Bio Co., Ltd. (Japan), Nutraceutical Corporation (US), and BASF SE (Germany) are strategically positioning themselves through innovation and partnerships. For instance, Kyowa Hakko Bio Co., Ltd. has focused on enhancing its product offerings by investing in research and development, which appears to bolster its market presence. Nutraceutical Corporation, on the other hand, emphasizes regional expansion and product diversification, thereby catering to a broader consumer base. Collectively, these strategies contribute to a moderately fragmented market structure, where competition is intensifying as companies seek to differentiate themselves through unique value propositions.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. This approach not only improves responsiveness to market demands but also aligns with sustainability goals, which are becoming paramount in consumer decision-making. The competitive structure of the L-Citrulline Market reflects a blend of established players and emerging entrants, each vying for market share through innovative solutions and strategic collaborations.

In August 2025, BASF SE (Germany) announced a partnership with a leading nutritional supplement brand to co-develop a new line of L-Citrulline Market products aimed at athletes. This collaboration is strategically significant as it allows BASF to leverage its expertise in ingredient formulation while tapping into the growing sports nutrition segment. Such partnerships are likely to enhance product visibility and credibility in a crowded marketplace.

Similarly, in July 2025, Nutraceutical Corporation (US) launched a new L-Citrulline Market supplement that incorporates advanced delivery technology, which is designed to improve bioavailability. This move not only showcases the company's commitment to innovation but also positions it favorably against competitors who may not offer similar advancements. The introduction of such products could potentially reshape consumer expectations and drive demand for higher-quality supplements.

In September 2025, Kyowa Hakko Bio Co., Ltd. (Japan) unveiled a sustainability initiative aimed at reducing the carbon footprint of its L-Citrulline Market production processes. This initiative reflects a growing trend among consumers who prioritize environmentally friendly products. By adopting sustainable practices, the company not only enhances its brand image but also aligns with global sustainability goals, which could resonate well with eco-conscious consumers.

As of October 2025, the competitive trends in the L-Citrulline Market are increasingly influenced by digitalization, sustainability, and the integration of artificial intelligence in product development and marketing strategies. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in enhancing innovation and market reach. Looking ahead, it appears that competitive differentiation will likely evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability, thereby reshaping the landscape of the L-Citrulline Market.

Key Companies in the L-Citrulline Market market include

Industry Developments

July 2021:

The three newest pre-workout supplements from Steel Supplements have been released, providing the endurance, energy, and power needed to get through the toughest exercises. The most recent exercises, Pumped AF, PRE, and N.O.7, are designed to help users, from novices to fitness enthusiasts, get the most out of their workouts. L-Theanine, L-Phenylalanine, Lion's Mane extract, Kre-Alkalyn, Beta-Alanine, Vitamins B12, B9, B3, B6, Caffeine Anhydrous, beetroot extract, L-Tyrosine, and L-Citrulline Market are a few of the important substances employed in these newest products. 

May 2021:

- Anther is the only patented, plant-based daily supplement created specifically for young and long-term penile wellness, and it is currently on sale at antherwellness.com. At age 30, most men begin to experience problems with those muscles, and from that point on, nature might continually test a man's strength to a greater extent. L-Citrulline Market, Ginger, Muira Puama, and Paullinia Cupana are just a few plant-based constituents in Anther. 

April 2018

: In the production facility located at Jombang, Indonesia, CJ CheilJedang Corp. declared its intentions to start a production line exclusively dedicated to producing l-arginine and l-citrulline.

Future Outlook

L-Citrulline Market Future Outlook

The L-Citrulline Market is projected to grow at a 5.12% CAGR from 2024 to 2035, driven by increasing health awareness, demand for dietary supplements, and advancements in production technologies.

New opportunities lie in:

  • Expansion into emerging markets with tailored formulations
  • Development of innovative delivery systems for enhanced bioavailability
  • Strategic partnerships with fitness and wellness brands for co-marketing initiatives

By 2035, the L-Citrulline Market is expected to achieve robust growth and increased market penetration.

Market Segmentation

L-Citrulline Market Type Outlook

  • Powder Type
  • Crystal Type

L-Citrulline Market Application Outlook

  • Cosmetic & Personal Care
  • Food & Beverages
  • Agriculture
  • Pharmaceuticals
  • Animal Feed
  • Other

L-Citrulline Market Classification Outlook

  • Medical Grade
  • Food Grade

Report Scope

MARKET SIZE 20240.13(USD Billion)
MARKET SIZE 20250.1367(USD Billion)
MARKET SIZE 20350.2252(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.12% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMarket analysis in progress
Segments CoveredMarket segmentation analysis in progress
Key Market OpportunitiesGrowing demand for natural supplements enhances opportunities in the L-Citrulline Market.
Key Market DynamicsRising consumer demand for dietary supplements drives innovation and competition in the L-Citrulline market.
Countries CoveredNorth America, Europe, APAC, South America, MEA

Market Highlights

Author
Anshula Mandaokar
Team Lead - Research

Anshula Mandaokar holds an academic degree in Chemical Engineering and has been contributing to the field for more than 5 years. She has expertise in Market Research and Business Consulting and serves as a Team Lead for a reputed Market Research firm under the Chemicals and Materials domain spectrum. She has worked on multiple projects, generating explicit results in a quick turnaround time. Her understanding of data interpretation justifies her role as a leader.

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FAQs

What is the current valuation of the L-Citrulline Market as of 2024?

The L-Citrulline Market was valued at 0.13 USD Billion in 2024.

What is the projected market valuation for L-Citrulline by 2035?

The market is projected to reach a valuation of 0.2252 USD Billion by 2035.

What is the expected CAGR for the L-Citrulline Market during the forecast period 2025 - 2035?

The expected CAGR for the L-Citrulline Market during 2025 - 2035 is 5.12%.

Which companies are considered key players in the L-Citrulline Market?

Key players include Kyowa Hakko Bio Co., Ltd., Nutraceutical Corporation, and BASF SE, among others.

What are the different types of L-Citrulline products available in the market?

The market offers Powder Type and Crystal Type L-Citrulline products.

How do the valuations of Powder Type and Crystal Type L-Citrulline compare?

In 2024, Powder Type was valued at 0.07 USD Billion, while Crystal Type was valued at 0.06 USD Billion.

What classifications exist within the L-Citrulline Market?

The market is classified into Medical Grade and Food Grade L-Citrulline.

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