Chronic Lymphocytic Leukemia Treatment Market Size, Growth and Trends Analysis by Type (Indolent & Aggressive), by Treatment (Chemotherapy, Targeted Drug Therapy, Immunotherapy & Bone Marrow Transplant), by End User (Hospitals & Clinics & Others) - Forecast Till 2027

Chronic Lymphocytic Leukemia Treatment Market

Chronic Lymphocytic Leukemia Treatment Market size was valued USD 7.9 Billion in 2017 and is expected exhibit CAGR of 19% over the forecast period (2018-2023). Chronic Lymphocytic Leukemia is a monoclonal disorder that affects the immune system and blood circulation system of the individual due to the overproduction of white blood cells in their blood. Emerging pipeline drugs, therapeutics, a combination of drugs, and other strategies are carried out in treating patients who are diagnosed with leukemia. The total count of Lymphocytes should be lesser than 5000 cells per microliter of blood. CLL and SLL are considered as underlying conditions which can be varied according to the difference in counts. 

The production of damaged lymphocytes is observed in the patients, which might cause improper functioning of antibodies. Such factors might lead to a poor immune system and can be fatal. Chronic lymphocytic leukemia is of two major types, one can be immediately fatal and the other is progressive. 

COVID 19 Analysis:

The Pandemic has increased the overall Chronic Lymphocytic Leukemia treatment market growth. Patients with blood cancer are more likely to acquire COVID infection, as their immune system gets weaker with the progress of treatment for blood cancer. A recent study states that there is a 57% of higher risk for cancer patients to acquire COVID infection. Moreover, the patients who have received chemotherapy are more likely to die of COVID infection; leukemia patients have increased the overall mortality rate during the pandemic. 

Such factors have propelled the medical associations to treat leukemia patients especially and undertake special strategies to treat them during the pandemics.

Market Dynamics:

Drivers:

Family history and aging are considered as the major causes of Chronic Lymphocytic Leukemia. Severe exposure to chemicals is also increasing the number of cases in western countries. However, countries like India are also increasingly showing up incidences in recent times. Such factors are driving the Chronic Lymphocytic Leukemia Treatment market growth.

The advent of pipeline therapies, increasing FDA approvals for the treatments and medication regarding Chronic Lymphocytic Leukemia are also increasing the overall growth of the Chronic Lymphocytic leukemia treatment industry.

Opportunities:

The increasing incidences of chronic lymphocytic leukemia condition in countries like the United States are presenting lucrative growth opportunities for Chronic Lymphocytic leukemia treatment market growth. The American cancer society claimed that there were over 20,490 cases in the year 2018 and every three minutes a patient is diagnosed with Chronic Lymphocytic leukemia condition in western countries. Such reports are expected to boost the overall growth of the Chronic Lymphocytic Leukemia Treatment industry in the forecast period.

The advent of novel technologies, a combination of drugs, and other strategies are expected to boost the overall growth of the chronic lymphocytic leukemia treatment market. Especially, the drug ibrutinib is found to be very effective in treating cancer, as it effectively attacks the cancer cells without causing any damage to the healthy cells, unlike chemotherapy. The drug administration is not invasive and is found to be very comfortable in treating such patients. 

Restraints:

Lack of awareness concerning the early signs and symptoms is considered as the primary restraining factor for the overall growth of the chronic lymphocytic leukemia treatment market. The under-developed countries, increasing geriatric population, lesser accessibility for quality treatments are some of the other restraining factors for the overall chronic lymphocytic leukemia treatment market.

The adverse effects of the prevalent treatments such as chemotherapy, leukapheresis are hindering the overall growth of the chronic lymphocytic leukemia treatment market. On the other hand, several branded drugs are banned in other parts of the world. Especially the drugs which contain Carcinogenic toxins that are banned in several parts of the world are hindering the overall growth of the chronic lymphocytic leukemia treatment market. Other restraining factors such as frequent modifications in treatments based on age and comorbidity and toxic management for the comorbid patients are also hindering the overall growth of the Chronic Lymphocytic leukemia treatment industry.

Challenges:

There are 3 types of Blood cancer, leukemia, lymphoma, and myeloma. Treating the patients, involve patiently watching the changes in the blood counts, as some cases might be developing, whereas some might be instantly fatal. Such factors are considered as the major challenge for the overall growth of the chronic lymphocytic leukemia treatment market.

Treating aged patients, and patients with comorbid patients are considered the primary challenge for the chronic lymphocytic leukemia treatment market. In some cases, those who are diagnosed with a higher number of CLL cells in the blood could be challenging, which causes leukostasis. The condition requires the removal of some cells from blood (leukapheresis). However such treatment has adverse effects such as lowering of blood counts.

Cumulative Growth Analysis:

The medical associations have worked to promote awareness on the Chronic Lymphocytic Leukemia Treatments in recent times, as the medical professionals assume that some of the causes of the condition can be mitigated and early diagnosis of the condition can help treat the patients a better way. For instance, improving the immune system and health life change can significantly reduce the occurrence of the condition. However, aging, family history, certain infections could also become the primary causes of Chronic Lymphocytic Leukemia. The global Chronic Lymphocytic Leukemia Treatment market size was at USD 9109 million in the year 2021 and expected to surpass USD 19220 million by the year 2027 while registering a CAGR of 10.9% in the forecast period. Blood cancer incidences were considered to be prevalent in the western countries, however, the cancer statistics state that there is one in every 260 women is affected by the condition, and one in 155 men is affected.

Value Chain Analysis:

Chronic Lymphocytic Leukemia is a monoclonal disorder that is commonly known as Blood cancer, diagnosed majorly in men from western countries. The increasing white blood cells in the blood causes the condition, especially when the lymphocyte count crosses over 5000 cells per microliter, and the count can be higher also. The patients who are diagnosed with Chronic Lymphocytic leukemia, based on the severity could die within 2-10 years. The earlier symptoms are significantly lower, however, the later stages show up symptoms such as non-painful lymph node swelling, sudden loss of appetite, early satiety, night sweats, loss of weight, weakness, fatigue. A report by Leukemia and Lymphoma Society has declared that a patient is being diagnosed with blood cancer every 3 minutes in western countries. Such factors state that there is a rising incidence of chronic Lymphocytic leukemia in western countries. 

The parenteral route of administration is found to be the most effective way of treating blood cancer. The parenteral route of administration of drugs is highly preferred as the drugs are rapidly absorbed and onset absorption. On the other hand, the advent of oral drugs which eliminates the necessity of chemotherapy is gaining preferences in recent years owing to the less invasive and efficient method of treating the condition. A combination of Venetoclax and Obinutuzumab is found to be effective.

Segment overview:

Based on Type of Cancer:

• B-cell Chronic Lymphocytic Leukemia


• T-cell Chronic Lymphocytic Leukemia


• Natural Chronic Lymphocytic Leukemia

Based on Therapy:

• Targeted Therapy


• Chemotherapy

Based on Route of Administration:

• Intravenous


• Subcutaneous


• Intrathecal Route


• Intramuscular


• Oral

Based on End-user applications:

• Hospitals


• Ambulatory Surgical Centers


• Cancer Institutes


• Research & Academic Institutes

Regional analysis:

Currently, North America is expected to dominate the Chronic Lymphocytic Leukemia Treatment Market share owing to the increasing number of Lymphocytic patients in the region. World Health Organization has declared that cancer is the primary cause of death across the globe. Additionally, a recent report from the National Cancer Institute has stated that over 1,735,350 cancer patients are fighting cancer in the year 2018 in the United States and over 609,640 patients have their life affected by cancer. Several organizations and key market layers have increased their investment in the market and increased their overall support to combat the condition. Such factors are propelling the overall growth of the chronic lymphocytic leukemia treatment market. Overall, Americas is suspected to dominate the market in the forecast period, owing to the recent report shared by Leukemia and Lymphoma society in the year 2018 states that there is a patient diagnosed with blood cancer every 3 minutes. This report has stimulated the overall growth of the chronic lymphocytic leukemia treatment market.

On the other hand, Europe is holding the largest Chronic Lymphocytic Leukemia Treatment market share. Europe is witnessing huge market growth, owing to the rising research and development activities in the region, European government has launched the scheme called as Europe’s beating Cancer plan in recent times which has assured to offer high-quality screening treatment, and has set significant goals such as prevention of the disease, early detection, diagnosis, and treatment, improve the quality of life for the cancer patients.

Competitive landscape:

• Hoffmann-La Roche Ltd


• GlaxoSmithKline plc


• CELGENE CORPORATION


• Genmab A/S


• Teva Pharmaceutical Industries Ltd.


• Genentech, Inc.


• Genzyme Corporation


• AbbVie Inc., Gilead, Novartis AG


• Johnson & Johnson Services


• AstraZeneca


• ONO PHARMACEUTICAL CO.


• TG Therapeutics,


• Ziopharm Oncology

Recent developments:

The novel invention for chronic lymphocytic leukemia which is a chemotherapy-free treatment has been announced by the National Institute of Health care Excellence. The treatment is administrating a combo of Venetoclax and Obinutuzumab, which has now gotten approval and is now available in the market. This dosage is given for over 12 months and is found to be effective as the healthy cells are not affected by the chemotherapy.

In the year 2020, Imbruvica has gotten approval from FDA, however, the drug had to be combined with Rituximab for the patients who were already diagnosed and treated for the Chronic Lymphocytic Leukemia condition. The drug combination is also suggested for patients with small lymphocytic lymphoma. The combination of drugs is found to be effective for patients in recent times.

Report overview:

This report has covered:

• Market overview


• COVID 19 Analysis


• Market dynamics


• Cumulative growth analysis


• Value chain analysis


• Segment overview


• Regional analysis


• Competitive landscape


• Recent developments