Chronic Idiopathic Constipation Market Summary
As per Market Research Future Analysis, the Chronic Idiopathic Constipation Market was valued at USD 4.57 Billion in 2023 and is projected to grow to USD 9.65 Billion by 2032, with a CAGR of 7.16% from 2024 to 2032. The market is driven by factors such as an aging population, increased accessibility to over-the-counter drugs, and a sedentary lifestyle. However, challenges include the availability of alternative treatments and reduced healthcare expenditure in developing countries. The COVID-19 pandemic has also influenced market dynamics, prompting changes in consumer behavior and healthcare practices. The North American region is the largest market, primarily due to a high prevalence of chronic constipation and significant healthcare investments.
Key Market Trends & Highlights
The Chronic Idiopathic Constipation Market is experiencing notable growth driven by various factors.
- Market Size in 2023: USD 4.57 Billion
- Projected Market Size by 2032: USD 9.65 Billion
- CAGR from 2024 to 2032: 7.16%
- Major Growth Drivers: Aging population and increased OTC drug accessibility
Market Size & Forecast
2023 Market Size: USD 4.57 Billion
2024 Projected Market Size: USD 5.21 Billion
2032 Projected Market Size: USD 9.65 Billion
CAGR (2024-2032): 7.16%
Major Players
Pfizer Inc (U.S.), Progenics Pharmaceuticals (U.S.), GlaxoSmithKline (U.K.), Sucampo Pharmaceuticals Inc (U.S.), Ironwood Pharmaceuticals (U.S.), Sanofi (France), Salix Pharmaceuticals Ltd (U.S.), Bayer (Germany)

Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review
Chronic idiopathic constipation is understood and referred to as an extremely widespread functional bowel disorder that causes distress amongst millions of people around the globe, especially during the forecast period. Some of the major features of the market that are contributing to the growing number of patients that are suffering from chronic idiopathic constipation include a sedentary lifestyle, a severe decrease in the intake of dietary fibers, and the rise in usage of anti-inflammatory agents.
COVID 19 Analysis
The COVID-19 pandemic has broken the internet and market trends and has circulated new opportunities and challenges. The pandemic is an incomparable global public health emergency. The arrival of the pandemic has affected almost every industry, and the long-term effects are projected to impact the industry growth during the forecast period that will be ending in 2028. The research analyst's ongoing research amplifies their research framework to ensure the inclusion of underlying COVID-19 issues and potential paths forward. The report discusses that the outbreak of the pandemic has forced people to bring about a change in their lifestyle and consumer preferences. The pandemic has further forced the global governments and public sector to take important steps like lockdown and strict measures that will impact the market and the demand that might result in losses during the forecast period that will be ending in 2028.
The government and market players are understanding the need to return to normalcy to keep the market functioning with the rising competition in the global market premises. The chronic idiopathic constipation market trends are expected to rise with the enhanced research and development initiatives that are prevailing in the global market premises amid the duration of the current forecast period of 2021-2028.
Chronic Idiopathic Constipation Market Dynamics
Drivers
Major factors that are expected to boost the growth of the chronic idiopathic constipation market in the forecast period are the rise in the aging population. The rising ease and accessibility of over-the-counter drugs for chronic idiopathic constipation is further anticipated to propel the growth of the global market. On the other hand, the accessibility of substitute treatments is further projected to impede the growth of the chronic idiopathic constipation market in the timeline period that will be ending in 2028.
Restraints
However, the chronic idiopathic constipation market size is witnessing a decrease in the diverse need for healthcare expenditure in a few advancing and developing countries that might further challenge the growth of the chronic idiopathic constipation market as expected shortly, especially during the ongoing forecast period that will be ending in 2028.
Technology Analysis
The target audience across the world is known to have accepted living a sedentary lifestyle alongside a severe degree of decrease in the intake of dietary fibers that are impacting the people and hence, giving rise to the chronic idiopathic constipation market. Also, the market trends show that there has been a rising degree of use for anti-inflammatory agents and agencies. The technological availability is welcoming the investments from various domestic and international companies and governments that are likely to provide the market with a good fortune and expansion rate during the ongoing forecast period that will be ending in 2028.
Study Objectives
- The global chronic idiopathic constipation market study aims to have a deep study of the global market functions before and after the novel coronavirus had hit the international market scale. The report aims to have an idea about the market dynamics like the opportunities and drivers that will help the market during the forecast period that will be ending in 2028. The market report also aims to develop an understanding of the restraints that might challenge the market from growing as per the predictions.
- The market report also discusses the basis of the global market segmentation through which the market is functioning in a series of global locations for meeting the rising needs of the target audience that is spread in the prominent places for the market and hence, help the market grow as per the potential revenue that has been forecasted for the period that will be ending in 2028.
- The chronic idiopathic constipation market report aims to have an idea about the rising market competition that is a result of the trends and developments that have been in the way of rising and expansion in the global industry during the ongoing forecast period and further, help the investors make better decisions.
Chronic Idiopathic Constipation Market Segmentation
The chronic idiopathic constipation market dynamics predict a good fortune for the market amid the rising market trends. The market is being recorded to perform at an excellent scale based on the global segmentation that is as follows:
Based on the diagnosis
The chronic idiopathic constipation market is segmented based on the diagnosis and includes blood tests, sigmoidoscopy, colonoscopy, balloon expulsion test, anorectal manometry, colonic transit study, defecography, and others.
Based on the treatment
The chronic idiopathic constipation market is segmented based on the treatment and includes drugs and surgery. Drugs have further been segmented into acid neutralizers, laxatives and antidiarrheal, antiemetics, antiulcer, lubiprostone (amitiza), and linaclotide (linzess), misoprostol (Cytotec), colchicine/probenecid (Col-Probenecid) alongside others like Onabotulinumtoxin A (also called botulinum toxin type A or Botox).
Based on the end-user industries
The chronic idiopathic constipation market is segmented based on the end-user industries and includes hospitals, gastroenterology clinics, diagnostic centers, and others.
Chronic Idiopathic Constipation Market Regional Analysis
The North American chronic idiopathic constipation market has been segmented into two domestic regions, namely, North America and South America. The North American region, being the largest market, is witnessing major growth trends during the forecast period ending in 2028. The growth is mainly driven due to the substantial increase in the prevalence of chronic constipation and the growing investment in the healthcare departments and infrastructure. Also, the U.S., as a part of North America is the largest market in the North American region owing to the huge and evolving presence of a large number of market players who are indulged in the manufacturing of medications for constipation.
Chronic Idiopathic Constipation Market Competitive Landscape
The global rise in the market premises during the ongoing forecast period of 2021-2028 is because of the splendid record and performance of the prominent players of the market that are stated as follows:
- Pfizer Inc (U.S.)
- Progenics Pharmaceuticals (U.S.)
- GlaxoSmithKline (U.K.)
- Sucampo Pharmaceuticals Inc (U.S.)
- Ironwood Pharmaceuticals (U.S.)
- Sanofi (France)
- Salix Pharmaceuticals Ltd (U.S.)
- Bayer (Germany)
Chronic Idiopathic Constipation Market Industry Developments
- Q1 2024: Ironwood Pharmaceuticals Announces FDA Approval of LINZESS® (linaclotide) for Pediatric Patients Aged 6-17 Years with Functional Constipation Ironwood Pharmaceuticals received FDA approval for an expanded indication of LINZESS® (linaclotide) to treat pediatric patients aged 6-17 years with functional constipation, marking a significant regulatory milestone in the chronic idiopathic constipation sector.
- Q2 2024: Takeda and Ferring Pharmaceuticals Announce Strategic Partnership to Co-Develop Novel Constipation Therapies Takeda and Ferring Pharmaceuticals entered a strategic partnership to co-develop new therapies targeting chronic idiopathic constipation, aiming to accelerate innovation and expand treatment options in the market.
- Q2 2024: Bausch Health Launches New Osmotic Laxative for Chronic Idiopathic Constipation in U.S. Market Bausch Health announced the commercial launch of a new osmotic laxative specifically indicated for chronic idiopathic constipation, expanding its gastrointestinal product portfolio in the United States.
- Q2 2024: Renexxion Ireland Receives FDA Fast Track Designation for Naronapride in Chronic Idiopathic Constipation Renexxion Ireland was granted FDA Fast Track designation for its investigational drug Naronapride, intended for the treatment of chronic idiopathic constipation, facilitating expedited regulatory review.
- Q3 2024: Ardelyx Announces Positive Phase 3 Results for Tenapanor in Chronic Idiopathic Constipation Ardelyx reported positive topline results from its Phase 3 clinical trial evaluating Tenapanor for chronic idiopathic constipation, supporting future regulatory submissions and potential market entry.
- Q3 2024: Vanda Pharmaceuticals Appoints New Chief Medical Officer to Lead Gastrointestinal Drug Development Vanda Pharmaceuticals appointed a new Chief Medical Officer to oversee its gastrointestinal drug development programs, including candidates for chronic idiopathic constipation.
- Q4 2024: Cosmo Pharmaceuticals Opens New Manufacturing Facility for Constipation Treatments in Italy Cosmo Pharmaceuticals inaugurated a new manufacturing facility in Italy dedicated to producing treatments for chronic idiopathic constipation, increasing its production capacity and supply chain resilience.
- Q4 2024: RedHill Biopharma Secures $30 Million Series C Funding to Advance Chronic Idiopathic Constipation Pipeline RedHill Biopharma closed a $30 million Series C funding round to support the development and commercialization of its chronic idiopathic constipation drug candidates.
- Q1 2025: Shionogi Receives EMA Approval for New CIC Drug in Europe Shionogi obtained European Medicines Agency (EMA) approval for its new chronic idiopathic constipation drug, enabling commercial launch across European markets.
- Q1 2025: Salix Pharmaceuticals Announces U.S. Launch of New Extended-Release Constipation Therapy Salix Pharmaceuticals launched a new extended-release therapy for chronic idiopathic constipation in the United States, expanding its gastrointestinal product offerings.
- Q2 2025: Progenity Inc. Signs Licensing Agreement with Major Pharma for CIC Diagnostic Platform Progenity Inc. entered a licensing agreement with a major pharmaceutical company to commercialize its diagnostic platform for chronic idiopathic constipation, aiming to improve patient management and outcomes.
- Q2 2025: Theravance Biopharma Announces Positive Results from Phase 2 Study of New CIC Treatment Theravance Biopharma announced positive results from a Phase 2 clinical study of its investigational treatment for chronic idiopathic constipation, supporting further development and potential regulatory filings.
While not a direct diagnostic tool for CIC itself, a significant development in the broader diagnostic approach for chronic bowel symptoms (including constipation) is the strong recommendation by major gastroenterology bodies (like the American College of Gastroenterology - ACG and British Society of Gastroenterology - BSG) to use non-invasive markers like C-reactive protein (CRP) and fecal calprotectin. These blood and stool tests help to effectively rule out inflammatory bowel disease (IBD) in patients with suspected Irritable Bowel Syndrome with Constipation (IBS-C) or unexplained chronic constipation, especially when alarm features are absent. This reduces the reliance on more invasive diagnostic procedures like colonoscopy unless specific alarm signs are present.
Report Overview
The chronic idiopathic constipation market report is focusing on the market developments for the period that will lead the way of the market towards growth during the forecast period that will be ending in 2028. The market report covers the basis of the market segmentation and the rising market potential to meet the needs of the target audience during the period.
Report Attribute/Metric |
Details |
Market Size 2023 |
4.57 (USD Billion) |
Market Size 2024 |
5.21 (USD Billion) |
Market Size 2032 |
9.65 (USD Billion) |
Compound Annual Growth Rate (CAGR) |
7.16 % (2024 - 2032) |
Report Coverage |
Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
Base Year |
2023 |
Market Forecast Period |
2024 - 2032 |
Historical Data |
2019 - 2023 |
  Geographies Covered |
  North America, Europe, Asia-Pacific, and Rest of the World (RoW) |
  Key Vendors |
  Actavis (U.S.), Chugai Pharmaceutical (Japan), Ferring International Center S.A.(Switzerland), Synergy Pharmaceuticals (U.S.), Pfizer Inc (U.S.), GlaxoSmithKline (U.K.), Sanofi (France), Bayer (Germany), Salix Pharmaceuticals Ltd (U.S.), Sucampo Pharmaceuticals Inc (U.S.), Ironwood Pharmaceuticals (U.S.), Progenics Pharmaceuticals (U.S.), F. Hoffmann-La Roche AG (Switzerland), Boehringer Ingelheim GmbH (Germany), Daewoong Co. Ltd.(South Korea), Synergy Pharmaceuticals, Inc. (U.S.) and others |
  Key Market Opportunities |
  New product launches and R&D Amongst major key Players |
  Key Market Drivers |
· Increasing number of patients having GI diseases · Disorders due to change in dietary pattern |
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Chronic Idiopathic Constipation Market Highlights:
Frequently Asked Questions (FAQ):
Chronic idiopathic constipation market is expected to expand at 7.16% CAGR from 2024-2032.
Early detection of GI diseases at a preventive stage is the primary driver of the global chronic idiopathic constipation market.
Low awareness of the treatment is the major factor expected to impede the global chronic idiopathic constipation market growth.
The Americas is expected to dominate the global chronic idiopathic constipation market till 2032 due to large number of cases of chronic constipation.
Pfizer Inc, Salix Pharmaceuticals Ltd, Bayer, Sucampo Pharmaceuticals Inc, GlaxoSmithKline, Ironwood Pharmaceuticals, Chugai Pharmaceutical, Synergy Pharmaceuticals, Boehringer Ingelheim GmbH, Progenics Pharmaceuticals, F. Hoffmann-La Roche AG, Daewoong Co. Ltd., Actavis, Synergy Pharmaceuticals, Inc., Ferring International Center S., and Sanofi are prominent players of the global chronic idiopathic constipation market.