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China Patient Derived Xenograft Model Market

ID: MRFR/HC/50977-HCR
200 Pages
Garvit Vyas
October 2025

China Patient-Derived Xenograft Model Market Research Report By Tumor Type (Lung Cancer, Pancreatic Cancer, Prostate Cancer, Breast Cancer, Other Cancer), By Model Type (Mice, Rats) andBy End-User (Pharmaceutical, Biopharmaceutical Companies, Academic & Research Institutes, CROs, CDMOs)- Forecast to 2035

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China Patient Derived Xenograft Model Market Infographic
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China Patient Derived Xenograft Model Market Summary

As per MRFR analysis, the China patient derived-xenograft-model market size was estimated at 18.97 USD Million in 2024.. The China patient derived-xenograft-model market is projected to grow from 21.49 USD Million in 2025 to 74.99 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 13.31% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The China patient derived-xenograft-model market is poised for substantial growth driven by advancements in personalized medicine and collaborative research efforts.

  • The market is witnessing a rising demand for personalized medicine, indicating a shift towards tailored therapeutic approaches.
  • Collaborative research initiatives among academic institutions and biotech companies are enhancing innovation in patient derived-xenograft models.
  • Regulatory support and streamlined approval processes are facilitating faster market entry for new therapies.
  • Key market drivers include the increasing cancer incidence and growing investment in cancer research, which are likely to propel market expansion.

Market Size & Forecast

2024 Market Size 18.97 (USD Million)
2035 Market Size 74.99 (USD Million)

Major Players

Charles River Laboratories (US), Crown Bioscience (US), Horizon Discovery (GB), OncoOne (US), The Jackson Laboratory (US), XenoTech (US), Celerion (US), CureMetrix (US)

China Patient Derived Xenograft Model Market Trends

This market is experiencing notable growth, driven by advancements in cancer research and personalized medicine.. This market is characterized by the use of human tumor tissues implanted into immunocompromised mice, allowing for the study of tumor behavior and treatment responses in a more clinically relevant context. As researchers seek to develop more effective therapies, the demand for these models is likely to increase. Furthermore, the emphasis on precision medicine is pushing the boundaries of traditional research methodologies, leading to a greater reliance on patient-derived models. This shift appears to be fostering collaborations between academic institutions and biotechnology firms, enhancing innovation in this field. In addition, regulatory support from governmental bodies is playing a crucial role in the expansion of the patient derived-xenograft-model market. Initiatives aimed at streamlining the approval processes for new therapies are encouraging investment in research and development. The growing awareness of the limitations of conventional animal models is prompting researchers to adopt patient-derived xenografts as a more reliable alternative. As the landscape of cancer treatment evolves, the patient derived-xenograft-model market is poised for further advancements, potentially leading to breakthroughs in therapeutic strategies and improved patient outcomes.

Rising Demand for Personalized Medicine

The patient derived-xenograft-model market is witnessing an increase in demand for personalized medicine approaches. Researchers are focusing on tailoring treatments based on individual patient profiles, which necessitates the use of patient-derived models to predict responses to therapies more accurately.

Collaborative Research Initiatives

There is a growing trend of collaboration between academic institutions and biotechnology companies within the patient derived-xenograft-model market. These partnerships are fostering innovation and accelerating the development of new therapies, as shared resources and expertise enhance research capabilities.

Regulatory Support and Streamlined Approvals

Regulatory bodies are providing support to the patient derived-xenograft-model market by streamlining approval processes for new therapies. This regulatory environment encourages investment in research and development, facilitating the adoption of patient-derived models in clinical settings.

China Patient Derived Xenograft Model Market Drivers

Increasing Cancer Incidence

The rising incidence of cancer in China is a critical driver for the patient derived-xenograft-model market. As cancer cases continue to escalate, the demand for innovative treatment options intensifies. According to the National Cancer Center of China, cancer is the leading cause of death, with an estimated 4.6 million new cases reported in 2020. This alarming trend necessitates advanced research models, such as patient derived xenografts, to facilitate the development of targeted therapies. Thus, this market is positioned to grow as researchers seek to understand tumor biology and test new drugs effectively.. The increasing focus on personalized medicine further amplifies this demand, as patient derived models provide insights into individual responses to therapies, potentially improving treatment outcomes.

Advancements in Biotechnology

Technological advancements in biotechnology are propelling the patient derived-xenograft-model market forward in China. Innovations in genetic engineering, cell culture techniques, and imaging technologies enhance the efficacy and reliability of xenograft models. These advancements enable researchers to create more accurate representations of human tumors, which is essential for drug testing and development. The biotechnology sector in China has seen substantial investment, with the market expected to reach approximately $200 billion by 2025. This influx of funding supports the development of sophisticated patient derived models, which are crucial for understanding cancer progression and treatment responses. As the patient derived-xenograft-model market evolves, these technological improvements are likely to play a pivotal role in shaping research outcomes and therapeutic strategies.

Regulatory Framework Enhancements

Enhancements in the regulatory framework surrounding biomedical Market Research Future are influencing the patient derived-xenograft-model market positively. The Chinese government has implemented policies aimed at streamlining the approval process for new therapies and research models. These regulatory improvements facilitate faster access to patient derived xenograft models for researchers, thereby accelerating the pace of innovation in cancer treatment. The National Medical Products Administration (NMPA) has been actively working to create a more conducive environment for clinical trials and research, which is likely to benefit the patient derived-xenograft-model market. As regulations become more favorable, the market may experience increased participation from both domestic and international stakeholders, further driving growth.

Growing Investment in Cancer Research

The surge in investment for cancer Market Research Future is a significant driver for the patient derived-xenograft-model market. Government initiatives and private sector funding are increasingly directed towards oncology research, with the aim of improving treatment modalities and patient outcomes. In 2021, the Chinese government allocated over $1 billion to cancer research initiatives, reflecting a commitment to combat this pressing health issue. This financial support fosters the development of patient derived xenograft models, which are essential for preclinical testing and understanding tumor behavior. As funding continues to grow, the patient derived-xenograft-model market is expected to expand, providing researchers with the necessary tools to innovate and advance cancer therapies.

Rising Awareness of Precision Medicine

The growing awareness of precision medicine among healthcare professionals and patients in China is a vital driver for the patient derived-xenograft-model market. As the healthcare landscape shifts towards personalized treatment approaches, the need for models that accurately reflect individual patient tumors becomes increasingly apparent. Educational initiatives and outreach programs are enhancing understanding of the benefits of precision medicine, leading to greater acceptance and demand for patient derived xenograft models. This shift is supported by a broader trend towards individualized therapies, which are projected to account for over 50% of oncology treatments by 2030. Consequently, The patient derived-xenograft-model market will thrive as it aligns with the evolving preferences of both clinicians and patients..

Market Segment Insights

By Tumor Type: Lung Cancer (Largest) vs. Pancreatic Cancer (Fastest-Growing)

In the China patient derived-xenograft-model market, Lung Cancer represents the largest segment, significantly outperforming other tumor types in market share distribution. This is largely driven by the high prevalence and incidence rates of lung cancer within the population, which creates a strong demand for effective treatment models. Meanwhile, Pancreatic Cancer is emerging as the fastest-growing segment, demonstrating an increasing recognition of its complexities and the need for advanced therapeutic approaches in a rapidly evolving research and clinical landscape. The growth trends for these tumor types are influenced by various factors such as advancements in research methodologies, increased funding for cancer research, and heightened awareness of personalized medicine applications. For Lung Cancer, established research protocols and a robust clinical framework contribute to its dominant position. Conversely, the rapid growth of Pancreatic Cancer models can be attributed to the expanding focus on previously neglected or under-researched cancers, signaling a shift in priorities towards comprehensive oncology solutions.

Lung Cancer (Dominant) vs. Pancreatic Cancer (Emerging)

Lung Cancer models dominate the China patient derived-xenograft-model market due to their established market presence and extensive research backing. The models used for lung cancer are often more advanced, resulting in higher adoption rates among researchers. In contrast, Pancreatic Cancer models are emerging rapidly as the market recognizes the urgent need for effective treatment strategies against this aggressive malignancy. These models are increasingly being integrated into clinical trials and research settings due to their potential to uncover novel therapeutic targets. The growing acknowledgment of the unique challenges associated with pancreatic cancer research is driving innovation and investment, positioning it as a key area of focus for future developments in the market.

By Model Type: Mice (Largest) vs. Rats (Fastest-Growing)

In the China patient derived-xenograft-model market, Mice constitute the largest segment, commanding a significant market share due to their established role in research and preclinical studies. Their well-documented genetic similarities to humans make them the preferred choice for various applications, resulting in robust demand within the research community. Rats, on the other hand, are emerging rapidly as a competitive segment. The growing interest in their use for specific disease models and drug testing contributes to their increasing market presence. The growth trends for this segment are fueled by advancements in genetic engineering and a rising focus on personalized medicine. Researchers are increasingly exploring the unique benefits that both Mice and Rats offer, leading to enhanced research outcomes. As the need for preclinical testing grows, both model types are expected to benefit; however, Rats are predicted to grow at a faster rate due to their versatility in studies involving complex human diseases and therapeutic approaches.

Mice: Dominant vs. Rats: Emerging

Mice have long been the dominant model type in the market, widely used in various disease studies and therapeutic tests owing to their genetic, biological, and behavioral similarities to humans. Their established protocols and ease of handling further solidify their preference among researchers. Conversely, Rats are emerging as a valuable alternative, particularly in the context of pharmacokinetic and pharmacodynamic studies due to their larger size and more complex physiology. This versatility positions Rats favorably for studies targeting intricate human diseases, supporting their rapid uptake in research settings. Both segments are likely to coexist, but with Rats gaining ground rapidly, they represent a burgeoning area within the market.

By End-user: Pharmaceutical and Biopharmaceutical Companies (Largest) vs. Academic & Research Institutes (Fastest-Growing)

In the China patient derived-xenograft-model market, the distribution among end-users reveals that pharmaceutical and biopharmaceutical companies hold the largest share. These industries leverage patient-derived xenograft models to streamline drug development processes and enhance therapeutic efficacy. In contrast, academic and research institutes are emerging strongly, utilizing these models for breakthrough research and innovative therapies, thus increasing their market presence. The growth trends in this segment indicate that while pharmaceutical and biopharmaceutical companies continue to dominate, academic and research institutes are demonstrating rapid expansion. Factors driving this growth include increased funding for cancer research, advancements in personalized medicine, and a greater emphasis on translational research, with academic entities seeking to adopt more sophisticated models to drive their discoveries forward.

Pharmaceutical and Biopharmaceutical Companies: Dominant vs. Academic & Research Institutes: Emerging

Pharmaceutical and biopharmaceutical companies remain the dominant players in the patient derived-xenograft model space, driven by their need for advanced solutions to facilitate drug development and testing. They benefit from greater financial resources and established infrastructures to integrate these models into their pipelines. On the other hand, academic and research institutes represent the emerging segment, increasingly engaging in partnerships with industry players and securing government and private funding. As they adopt patient-derived models, these institutes are expected to accelerate innovations in treatments, particularly in oncology, addressing unmet medical needs. Their adaptability and focus on research excellence place them in a favorable position to influence the market significantly in the coming years.

Get more detailed insights about China Patient Derived Xenograft Model Market

Key Players and Competitive Insights

The patient derived-xenograft-model market is currently characterized by a dynamic competitive landscape, driven by increasing demand for personalized medicine and advancements in oncology research. Key players such as Charles River Laboratories (US), Crown Bioscience (US), and Horizon Discovery (GB) are strategically positioned to leverage their expertise in preclinical models and drug development. Charles River Laboratories (US) focuses on innovation through the development of advanced xenograft models that enhance translational research, while Crown Bioscience (US) emphasizes partnerships with pharmaceutical companies to optimize drug discovery processes. Horizon Discovery (GB) appears to be concentrating on expanding its portfolio of genetically engineered models, which collectively shapes a competitive environment that is increasingly reliant on technological advancements and collaborative efforts.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure is moderately fragmented, with several players vying for market share, yet the influence of major companies is palpable. This competitive structure fosters an environment where innovation and strategic partnerships are paramount, as companies seek to differentiate themselves in a crowded marketplace.

In October 2025, Charles River Laboratories (US) announced a collaboration with a leading biopharmaceutical company to develop a novel patient-derived xenograft model aimed at accelerating the drug development process. This strategic move underscores the importance of partnerships in enhancing research capabilities and demonstrates Charles River's commitment to innovation in the field. Such collaborations are likely to enhance their competitive edge by providing access to cutting-edge technologies and expertise.

In September 2025, Crown Bioscience (US) expanded its operations in China by establishing a new facility dedicated to patient-derived xenograft models. This expansion is indicative of the company's strategy to localize its services and cater to the growing demand for personalized medicine in the region. By enhancing its operational footprint, Crown Bioscience is poised to strengthen its market position and improve service delivery to clients in the Asia-Pacific region.

In August 2025, Horizon Discovery (GB) launched a new suite of genetically engineered patient-derived xenograft models designed to mimic specific tumor microenvironments. This launch reflects Horizon's focus on innovation and its commitment to providing researchers with tools that can facilitate more accurate preclinical testing. The introduction of these models is likely to attract interest from pharmaceutical companies seeking to enhance their drug development pipelines.

As of November 2025, current competitive trends in the patient derived-xenograft-model market include a pronounced shift towards digitalization, sustainability, and the integration of artificial intelligence in research processes. Strategic alliances are increasingly shaping the landscape, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is expected to evolve, with a greater emphasis on technological advancements and supply chain reliability, rather than solely on price. This shift suggests that companies that prioritize innovation and strategic partnerships will likely emerge as leaders in the market.

Key Companies in the China Patient Derived Xenograft Model Market market include

Industry Developments

In recent months, the China Patient-Derived Xenograft Model Market has experienced significant activity, particularly with key players such as Crown Bioscience, Thermo Fisher Scientific, and Charles River Laboratories. Notably, in July 2023, Crown Bioscience announced an expansion of its capabilities in China, enhancing its offering of preclinical services aimed at improving drug discovery processes. Meanwhile, Thermo Fisher Scientific has been increasing its investment in Research and Development in the region to bolster its presence in the oncology market.

In terms of mergers and acquisitions, Jinshan Science & Technology has been in discussions for a potential partnership with a leading biotech firm focused on immuno-oncology solutions, indicative of a trend towards consolidating resources to leverage advanced therapies. Furthermore, the market valuation has shown growth, largely driven by increasing demand for personalized medicine, with projections indicating a compound annual growth rate of approximately 15% for the next five years. Regulatory approvals from governing bodies in China have also streamlined the process for bringing new xenograft models to market, thereby promoting innovation and competitive dynamics.

In the broader context, the focus on patient-specific therapies has garnered governmental support, enhancing collaboration within the industry.

Future Outlook

China Patient Derived Xenograft Model Market Future Outlook

The Patient Derived Xenograft Model Market in China is projected to grow at a 13.31% CAGR from 2024 to 2035, driven by advancements in personalized medicine and increasing R&D investments.

New opportunities lie in:

  • Development of tailored xenograft models for specific cancer types
  • Partnerships with biotech firms for innovative drug testing
  • Expansion of biorepository services for patient-derived samples

By 2035, the market is expected to achieve substantial growth, reflecting its critical role in cancer research.

Market Segmentation

China Patient Derived Xenograft Model Market End-user Outlook

  • Pharmaceutical and Biopharmaceutical Companies
  • Academic & Research Institutes
  • CROs & CDMOs

China Patient Derived Xenograft Model Market Model Type Outlook

  • Mice
  • Rats

China Patient Derived Xenograft Model Market Tumor Type Outlook

  • Lung Cancer
  • Pancreatic Cancer
  • Prostate Cancer
  • Breast Cancer
  • Other Cancer

Report Scope

MARKET SIZE 2024 18.97(USD Million)
MARKET SIZE 2025 21.49(USD Million)
MARKET SIZE 2035 74.99(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 13.31% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Charles River Laboratories (US), Crown Bioscience (US), Horizon Discovery (GB), OncoOne (US), The Jackson Laboratory (US), XenoTech (US), Celerion (US), CureMetrix (US)
Segments Covered Tumor Type, Model Type, End-user
Key Market Opportunities Advancements in personalized medicine drive demand for innovative patient derived-xenograft-model solutions.
Key Market Dynamics Rising demand for personalized medicine drives growth in patient derived-xenograft-model applications and innovations.
Countries Covered China

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FAQs

What is the projected market size of the China Patient-Derived Xenograft Model Market by 2035?

The market is expected to be valued at 87.24 million USD by 2035.

What was the market value of the China Patient-Derived Xenograft Model Market in 2024?

In 2024, the market is valued at 22.4 million USD.

What is the expected compound annual growth rate (CAGR) for the China Patient-Derived Xenograft Model Market from 2025 to 2035?

The expected CAGR for the market is 13.156 percent from 2025 to 2035.

Which tumor type holds the largest market share in the China Patient-Derived Xenograft Model Market in 2024?

Lung cancer holds the largest market share valued at 6.72 million USD in 2024.

Which key players are leading the China Patient-Derived Xenograft Model Market?

Major players include Crown Bioscience, Thermo Fisher Scientific, and Charles River Laboratories.

What is the market value of pancreatic cancer in the China Patient-Derived Xenograft Model Market for 2024?

The market value for pancreatic cancer in 2024 is 4.48 million USD.

What growth is anticipated for breast cancer in the China Patient-Derived Xenograft Model Market by 2035?

The market for breast cancer is expected to reach 21.43 million USD by 2035.

What challenges may affect the growth of the China Patient-Derived Xenograft Model Market?

Emerging regulations and competition from alternative models may challenge market growth.

What is the projected market size for prostate cancer in 2035?

The market size for prostate cancer is projected to be 14.75 million USD in 2035.

How does the growth rate of the China Patient-Derived Xenograft Model Market compare across different tumor types from 2025 to 2035?

Growth rates vary, with lung cancer showing significant demand and expansion during this period.

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