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Blood Plasma Derivatives Market

ID: MRFR/Pharma/0817-HCR
80 Pages
Rahul Gotadki
October 2025

Blood Plasma Derivatives Market Research Report Information by Type [Factor VIII Concentrate, Factor IX Concentrate, Albumin, Immune Globulins, Anti-Thrombin III Concentrate, and Fresh Frozen Plasma (FFP)], Application (HIV, Hemophilia A, Hemophilia B, Hepatitis B, Hepatitis C, Bleeding Disorders, Hypogammaglobulinemia, Immunodeficiency Diseases, and Others), End User (Hospitals & Clinics, Blood Transfusion Centers, Diagnostic Centers, and Others), and Region (Americas, Europe, Asia-Pacific, and Middle East & Africa)—Foreca... read more

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Blood Plasma Derivatives Market Summary

As per MRFR analysis, the Blood Plasma Derivatives Market Size was estimated at 43.3 USD Billion in 2024. The Blood Plasma Derivatives industry is projected to grow from 46.6 USD Billion in 2025 to 86.67 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 6.47 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Blood Plasma Derivatives Market is experiencing robust growth driven by technological advancements and rising demand across various segments.

  • Technological advancements in production are enhancing the efficiency and quality of blood plasma derivatives.
  • The demand for immunoglobulins is rising significantly, reflecting a growing focus on immunology treatments.
  • North America remains the largest market, while the Asia-Pacific region is emerging as the fastest-growing area for blood plasma derivatives.
  • Increasing prevalence of chronic diseases and growing awareness of plasma donation are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 43.3 (USD Billion)
2035 Market Size 86.67 (USD Billion)
CAGR (2025 - 2035) 6.47%

Major Players

Grifols (ES), CSL Behring (AU), Takeda Pharmaceutical Company Limited (JP), Octapharma (CH), Kedrion S.p.A. (IT), Biotest AG (DE), LFB Group (FR), Hualan Biological Engineering Inc. (CN)

Blood Plasma Derivatives Market Trends

The Blood Plasma Derivatives Market is currently experiencing a dynamic evolution, driven by advancements in medical technology and an increasing demand for therapeutic products derived from human plasma. This market encompasses a wide range of products, including immunoglobulins, clotting factors, and albumin, which are essential for treating various medical conditions such as immune deficiencies, hemophilia, and liver diseases. The growing awareness of the benefits of plasma-derived therapies is likely to propel market growth, as healthcare providers and patients alike recognize their efficacy and safety. Furthermore, the expansion of healthcare infrastructure in emerging economies appears to contribute positively to the market's trajectory, as access to these vital treatments becomes more widespread. In addition to technological advancements, regulatory frameworks are evolving to ensure the safety and quality of blood plasma products. This regulatory scrutiny may enhance consumer confidence, thereby fostering market expansion. The Blood Plasma Derivatives Market also seems to be influenced by the increasing prevalence of chronic diseases, which necessitate ongoing treatment and management. As the global population ages, the demand for plasma-derived therapies is expected to rise, potentially leading to further innovations in product development and manufacturing processes. Overall, the Blood Plasma Derivatives Market is poised for continued growth, driven by a confluence of factors that underscore the importance of these life-saving therapies.

Technological Advancements in Production

Recent innovations in the manufacturing processes of blood plasma derivatives are enhancing efficiency and product quality. Techniques such as fractionation and purification are becoming more sophisticated, allowing for higher yields and reduced contamination risks. This trend indicates a shift towards more sustainable practices in the industry, which may attract investment and improve market competitiveness.

Rising Demand for Immunoglobulins

The demand for immunoglobulins is on the rise, primarily due to their critical role in treating autoimmune disorders and immunodeficiencies. As awareness of these conditions grows, healthcare providers are increasingly prescribing immunoglobulin therapies, which could lead to a substantial increase in market share for this segment. This trend suggests a potential shift in treatment paradigms, emphasizing the importance of plasma-derived products.

Expansion in Emerging Markets

Emerging markets are witnessing a notable expansion in the Blood Plasma Derivatives Market, driven by improving healthcare infrastructure and rising disposable incomes. As access to healthcare improves, the demand for plasma-derived therapies is likely to increase, presenting opportunities for market players to establish a foothold in these regions. This trend may lead to a more globalized market landscape.

Blood Plasma Derivatives Market Drivers

Rising Demand for Immunoglobulins

The Global Blood Plasma Derivatives Market Industry experiences a notable surge in demand for immunoglobulins, primarily driven by their therapeutic applications in treating immune deficiencies and autoimmune disorders. As healthcare providers increasingly recognize the efficacy of immunoglobulins, the market is projected to reach 51.0 USD Billion in 2024. This growth is indicative of a broader trend towards personalized medicine, where immunoglobulins play a crucial role in patient care. The increasing prevalence of chronic diseases further fuels this demand, suggesting that the Global Blood Plasma Derivatives Market Industry is poised for sustained expansion.

Growing Awareness of Rare Diseases

The Global Blood Plasma Derivatives Market Industry is witnessing an increase in awareness and diagnosis of rare diseases, which often require specialized plasma-derived therapies. As healthcare systems improve their capabilities to identify and treat these conditions, the demand for specific plasma derivatives, such as clotting factors and albumin, is expected to rise. This trend is likely to contribute to the market's projected compound annual growth rate of 8.52% from 2025 to 2035. The growing focus on rare diseases underscores the importance of plasma derivatives in modern medicine, positioning the Global Blood Plasma Derivatives Market Industry for significant growth.

Emerging Markets and Global Expansion

Emerging markets are playing a pivotal role in the growth of the Global Blood Plasma Derivatives Market Industry. Countries in Asia-Pacific and Latin America are experiencing rapid economic development, leading to increased healthcare spending and improved access to plasma-derived therapies. This trend is likely to drive demand for various plasma products, contributing to the overall market growth. As these regions continue to develop their healthcare infrastructure, the Global Blood Plasma Derivatives Market Industry is expected to expand significantly, reflecting the changing dynamics of global healthcare.

Regulatory Support for Plasma Products

Regulatory frameworks supporting the development and distribution of plasma-derived products are crucial for the Global Blood Plasma Derivatives Market Industry. Governments and health authorities are increasingly recognizing the therapeutic value of these products, leading to streamlined approval processes and enhanced funding for research and development. This supportive environment encourages innovation and investment in the sector, which is essential for meeting the rising global demand for plasma derivatives. As a result, the market is expected to thrive, with projections indicating a substantial increase in value over the coming years.

Advancements in Plasma Collection Technologies

Technological advancements in plasma collection and processing are significantly impacting the Global Blood Plasma Derivatives Market Industry. Innovations such as automated collection systems and improved separation techniques enhance the efficiency and safety of plasma donation. These advancements not only increase the yield of plasma derivatives but also improve donor experience, thereby attracting more individuals to donate. As a result, the market is likely to benefit from a more robust supply chain, supporting the anticipated growth trajectory towards 125.3 USD Billion by 2035. This evolution in technology indicates a promising future for the Global Blood Plasma Derivatives Market Industry.

Market Segment Insights

By Application: Immunology (Largest) vs. Oncology (Fastest-Growing)

The Blood Plasma Derivatives Market is largely influenced by its application segments. Immunology holds a significant share as it encompasses a range of therapeutic products that are crucial for treating autoimmune diseases, allergies, and other health issues related to immune response. In contrast, the oncology segment is rapidly emerging, driven by increased cancer prevalence and advances in treatment methods, which are propelling its growth in the market.

Immunology (Dominant) vs. Oncology (Emerging)

The immunology segment is currently dominant in the Blood Plasma Derivatives Market, reflecting its critical role in managing immune-related conditions. Immunoglobulins, primarily used for immunotherapy, account for a substantial proportion of this segment due to their efficacy and wide range of applications. Meanwhile, oncology is recognized as an emerging segment, witnessing rapid development fueled by innovative therapeutic approaches, including antibody-drug conjugates and personalized medicine. As the demand for effective cancer treatments escalates, the oncology application is expected to seize a larger market share, driven by ongoing research and a growing focus on targeted therapies.

By Product Type: Albumin (Largest) vs. Immunoglobulin (Fastest-Growing)

In the Blood Plasma Derivatives Market, Albumin holds the largest market share, primarily due to its extensive applications in various medical treatments and its essential role in maintaining oncotic pressure. It accounts for a significant portion of the market owing to its prominence in therapeutic uses, including treatment for burns, liver cirrhosis, and other conditions requiring volume expansion. On the other hand, Immunoglobulin is rapidly gaining traction, reflecting considerable growth as it is increasingly utilized in immunotherapy and treatment of autoimmune diseases, indicating a shift in demand dynamics among healthcare providers.

Albumin (Dominant) vs. Immunoglobulin (Emerging)

Albumin remains the dominant product in the Blood Plasma Derivatives Market, valued for its versatility and effectiveness. It is a critical protein used in various formulations and therapies, establishing a reliable stream of demand from hospitals and clinics. In contrast, Immunoglobulin is emerging as a significant player due to its growing application in treatments for immune deficiencies and autoimmune disorders. The rising awareness of immunotherapy's benefits contributes to its rapid growth. As healthcare trends evolve, Immunoglobulin is set to not only expand its market presence but also transform treatment approaches, creating opportunities for innovation within the industry.

By End Use: Hospitals (Largest) vs. Blood Banks (Fastest-Growing)

In the Blood Plasma Derivatives Market, hospitals represent the largest segment, reflecting their critical need for plasma products in various treatments, including surgeries and trauma care. This segment's substantial market share is driven by increasing hospital admissions and the rising prevalence of chronic diseases that require blood plasma derivatives for effective management. Furthermore, blood banks are the fastest-growing segment, responding to heightened awareness about the importance of plasma donations and improved collection technologies.

Hospitals (Dominant) vs. Blood Banks (Emerging)

Hospitals play a dominant role in the Blood Plasma Derivatives Market due to their extensive use of plasma products for patient care. They rely heavily on these derivatives for critical treatments and therapies, thereby solidifying their position as major consumers in this market. In contrast, blood banks are an emerging segment, gaining momentum as they enhance plasma collection processes and donor outreach programs. The growth of blood banks is fueled by the increasing demand for plasma-derived therapies amid a rising global health consciousness, making them an essential player in the distribution of blood plasma derivatives.

Get more detailed insights about Blood Plasma Derivatives Market

Regional Insights

North America : Market Leader in Plasma Derivatives

North America continues to lead the Blood Plasma Derivatives Market, holding a significant share of 21.8% in 2024. The region's growth is driven by increasing demand for immunoglobulin therapies and advancements in plasma collection technologies. Regulatory support from agencies like the FDA further catalyzes market expansion, ensuring safety and efficacy in plasma-derived products. The competitive landscape is robust, with key players such as Grifols, CSL Behring, and Takeda Pharmaceutical Company Limited dominating the market. The U.S. remains the largest contributor, supported by a well-established healthcare infrastructure and a growing patient population requiring plasma therapies. This competitive environment fosters innovation and enhances product offerings, solidifying North America's position as a market leader.

Europe : Emerging Market with Growth Potential

Europe's Blood Plasma Derivatives Market is valued at €12.9 billion, reflecting a growing demand for plasma-based therapies. Factors such as an aging population and rising incidences of chronic diseases are driving this growth. Regulatory frameworks, including the European Medicines Agency's guidelines, are pivotal in ensuring product safety and efficacy, thus enhancing consumer confidence in plasma therapies. Leading countries like Germany, France, and the UK are at the forefront of this market, with significant contributions from companies like Octapharma and LFB Group. The competitive landscape is characterized by strategic partnerships and collaborations aimed at expanding product portfolios and improving distribution networks. This dynamic environment positions Europe as a key player in The Blood Plasma Derivatives.

Asia-Pacific : Rapidly Growing Market Segment

The Asia-Pacific region, with a market size of $7.5 billion, is witnessing rapid growth in the Blood Plasma Derivatives Market. Factors such as increasing healthcare expenditure, rising awareness about plasma therapies, and supportive government initiatives are driving this expansion. Countries like China and Japan are leading the charge, with significant investments in healthcare infrastructure and plasma collection facilities. The competitive landscape is evolving, with local players and multinational companies like Hualan Biological Engineering Inc. and Takeda Pharmaceutical Company Limited vying for market share. The region's growth potential is further enhanced by collaborations between public and private sectors, aimed at improving plasma collection and processing capabilities, thereby meeting the rising demand for plasma-derived products.

Middle East and Africa : Emerging Market with Challenges

The Blood Plasma Derivatives Market in the Middle East and Africa is valued at $1.1 billion, reflecting its emerging status in the global landscape. The region faces challenges such as limited healthcare infrastructure and regulatory hurdles, which hinder market growth. However, increasing awareness of plasma therapies and rising healthcare investments are expected to drive future growth. Countries like South Africa and the UAE are making strides in developing their plasma collection and processing capabilities. The presence of key players, although limited, is gradually increasing, with companies exploring opportunities to expand their footprint in this region. Collaborative efforts between governments and private entities are essential to overcome existing challenges and enhance market potential.

Key Players and Competitive Insights

The Blood Plasma Derivatives Market is characterized by a dynamic competitive landscape, driven by increasing demand for immunoglobulins and clotting factor concentrates. Key players are actively pursuing strategies that emphasize innovation, regional expansion, and strategic partnerships to enhance their market positions. Companies such as Grifols (ES), CSL Behring (AU), and Takeda Pharmaceutical Company Limited (JP) are at the forefront, leveraging their extensive product portfolios and global reach to capture emerging opportunities. Their collective focus on research and development, alongside strategic mergers and acquisitions, appears to be shaping a competitive environment that is both robust and evolving.

In terms of business tactics, companies are increasingly localizing manufacturing to reduce supply chain vulnerabilities and optimize operational efficiencies. The market structure is moderately fragmented, with a few dominant players exerting considerable influence. This fragmentation allows for niche players to thrive, yet the presence of major companies like Octapharma (CH) and Kedrion S.p.A. (IT) ensures that competition remains fierce, particularly in regions with high demand for plasma-derived therapies.

In November 2025, Grifols (ES) announced a strategic partnership with a leading biotechnology firm to enhance its research capabilities in rare disease treatments. This collaboration is expected to bolster Grifols' product pipeline and position it as a leader in innovative therapies, reflecting a broader trend towards specialization in the market. Such partnerships may not only accelerate product development but also enhance the company's competitive edge in a rapidly evolving landscape.

In October 2025, CSL Behring (AU) expanded its manufacturing facility in Germany, a move aimed at increasing production capacity for its immunoglobulin products. This expansion is significant as it aligns with the growing global demand for immunoglobulins, particularly in Europe. By enhancing its manufacturing capabilities, CSL Behring is likely to improve its supply chain reliability and responsiveness to market needs, thereby strengthening its market position.

In September 2025, Takeda Pharmaceutical Company Limited (JP) launched a new digital platform aimed at streamlining patient access to plasma-derived therapies. This initiative reflects a growing trend towards digitalization within the industry, as companies seek to enhance patient engagement and improve service delivery. By integrating technology into its operations, Takeda is positioning itself to meet the evolving expectations of healthcare providers and patients alike.

As of December 2025, current trends in the Blood Plasma Derivatives Market indicate a shift towards digitalization, sustainability, and the integration of artificial intelligence in operational processes. Strategic alliances are increasingly shaping the competitive landscape, allowing companies to pool resources and expertise. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability, underscoring the importance of agility in responding to market demands.

Key Companies in the Blood Plasma Derivatives Market market include

Industry Developments

June 2023: Grigols (Spain) Group and Canadian Plasma Resources sign a contract to guarantee the availability of plasma in Canada.  Grifols and their agreement state that by 2026, Grifols will produce 2.4 million grams of Ig medications annually after progressively growing their Canadian plasma supply 

April 2023: Biotest AG (Germany) opens its 10th plasma collection centre in Germany. Biotest is thus continuing the planned expansion of its own donation centres in Europe to contribute to more plasma collection after the plasma shortage in Germany and Europe 

Future Outlook

Blood Plasma Derivatives Market Future Outlook

The Blood Plasma Derivatives Market is projected to grow at a 6.47% CAGR from 2024 to 2035, driven by increasing demand for immunoglobulins and advancements in collection technologies.

New opportunities lie in:

  • Expansion of plasma collection centers in emerging markets.
  • Development of novel therapies utilizing plasma-derived products.
  • Investment in automated processing technologies for efficiency gains.

By 2035, the market is expected to achieve robust growth, positioning itself as a leader in biopharmaceuticals.

Market Segmentation

Blood Plasma Derivatives Market End Use Outlook

  • Hospitals
  • Clinics
  • Research Laboratories
  • Blood Banks
  • Pharmaceutical Companies

Blood Plasma Derivatives Market Application Outlook

  • Immunology
  • Hematology
  • Neurology
  • Oncology
  • Infectious Diseases

Blood Plasma Derivatives Market Product Type Outlook

  • Albumin
  • Immunoglobulin
  • Coagulation Factors
  • Clotting Factor Concentrates
  • Fibrinogen

Report Scope

MARKET SIZE 202443.3(USD Billion)
MARKET SIZE 202546.6(USD Billion)
MARKET SIZE 203586.67(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)6.47% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledGrifols (ES), CSL Behring (AU), Takeda Pharmaceutical Company Limited (JP), Octapharma (CH), Kedrion S.p.A. (IT), Biotest AG (DE), LFB Group (FR), Hualan Biological Engineering Inc. (CN)
Segments CoveredApplication, Product Type, End Use
Key Market OpportunitiesAdvancements in therapeutic applications drive growth in the Blood Plasma Derivatives Market.
Key Market DynamicsRising demand for immunoglobulins drives innovation and competition in the Blood Plasma Derivatives Market.
Countries CoveredNorth America, Europe, APAC, South America, MEA

Market Highlights

Author
Rahul Gotadki
Assistant Manager

He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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FAQs

What Would Be The Projected CAGR of the Blood Plasma Derivatives Market During the Forecast Period Of 2024 to 2032?

The Projected CAGR Would be 9.41% During The Forecast Period of 2024-2032.

Name The End Users Involved In The Blood Plasma Derivatives Market.

The Involved End Users Are Diagnostic Centers, Blood Transfusion Centers, Hospitals & Clinics, And Others.

Name The Type Leading In The Blood Plasma Derivatives Market.

The Immune Globulins Segment To Lead The Market.

Name The Application To Dominate The Blood Plasma Derivatives Market.

The Immunodeficiency Segment Would Head The Market.

Which Region Would Helm The Blood Plasma Derivatives Market?

The Americas Would Lead The Market.

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