Biomaterials Market Research Report: Information By Type (Metallic, Ceramics, Polymeric, Natural Biomaterials), by Application (Joint Replacements, Ophthalmology, Cardiovascular, Wound Healing, Plastic Surgery, Neurological Conditions, and Others) - Forecast till 2030

Biomaterials Market Forecast

The biomaterials market size is projected to be worth USD 212.40 billion by 2030, registering a CAGR of 7.80% during the forecast period (2022-2030)

A biomaterial is a substance that has been engineered to interact with biological systems and employed in medical technology to improve the function of damaged tissues, bones, and organs. The biomaterials market has been segmented based on type, and application. The market is driven by factors like the rising prevalence of cardiovascular diseases, growing demand for implantable devices, and expansion in the usage scope of biomaterials make the biomaterials market lucrative. However, the high price of implantable biomaterials could hamper the growth of the biomaterials market.

Biomaterials Market COVID-19 Analysis

The COVID-19 pandemic has interrupted the healthcare sector globally. The disease has forced several industries to shut down temporarily, including several sub-domains of the healthcare sector. The revenue of the global biomaterials market also declined in 2020 due to the global economic recession led by COVID-19. The COVID-19 pandemic affected the global economy as well as showed a huge impact on the functioning of general hospital care across the globe. As many hospitals and clinics remained closed due to lockdowns, the demand for orthopedic implants is expected to be subdued in the short term, which also decreases the demand for biomaterials. For instance, according to an article published in the British Journal of Surgery, in May 2020, around 28.4 million elective surgeries globally were predicted to be canceled or postponed 2020. Thus, with the delays of non-emergent services the demand for biomaterials decreases.

Biomaterials Market Dynamics

Drivers

• Rise in prevalence of cardiovascular diseases
  
  
  
  • Cardiovascular disease is the leading cause of death globally. Although surgical and pharmacological interventions dramatically improve cardiovascular patients' quality of life, cheaper and less invasive procedures are always preferable. Additionally, biomaterials exhibit great potential in cardiac repair and regeneration. The injectable biomaterials application includes increased angiogenesis, decreased left ventricular dilatation, and preservation of cardiac function. Therefore, the growing prevalence of cardiovascular diseases is thus, projected to fuel this market growth during the forecast period. For instance, according to the Centers for Disease Control and Prevention (CDC) estimates that cardiovascular disease is the leading cause of death in the US, contributing to an estimate of 1 in 4 deaths every year.
  
  
  
  


• Growing demand for implantable devices


• Expansion in the usage scope of biomaterials

Market Restraints

• Stringent clinical & regulatory processes
  
  
  
  • Biomaterial devices have undergone a stringent clinical and regulatory process to ensure their efficacy as well as their quality. The major reason for this is the fact that most biomaterial devices are implantable. Hence, before their market approval, they need to undergo various clinical and regulatory processes which are very complicated, depending on composition, and restrictive. This makes the market players apprehensive about investing in this market. Hence, these aforementioned are expected to restrain the market growth during the forecast period.
  
  
  
  


• High price of the implantable biomaterials

Market Opportunities

• Growing healthcare market in emerging economies
  
  
  
  • The biomaterials market is expected to witness significant growth in emerging countries during the forecast period. That is attributed to the rising adoption of implantable devices, increasing patient population, growing awareness of CVDs, improving healthcare infrastructure, rising disposable income, and the presence of less-stringent regulatory guidelines compared to developed countries in these countries. However, Brazil, Russia, India, China, and South Africa (BRICS) are among the fastest-growing economies in the world.
  
  
  • The growing demand for surgical procedures, and the increasing incidence of target diseases are some of the significant factors expected to drive the demand for novel medical devices, and advanced healthcare services in the respective healthcare systems of these countries. Hence, this is expected to offer imaginable growth possibilities to players operating in the biomaterials market in the coming years.
  
  
  
  

Value Chain Analysis

The global biomaterials market is projected to exhibit significant growth over the forecast period, which can be attributed to factors such as the various applications of biomaterials and increasing R&D initiatives. The value chain analysis for the market comprises four major components, which start with research & product development, followed by the manufacturing of the products, distribution & sales, and ends with post-marketing surveillance.

Biomaterials Market Segmentation

By Type

• Metallic

Metallic biomaterials provide internal support to biological tissues. They are most preferred and are largely used for joint replacements, dental implants, stents, and orthopedic fixations. Their increasing adoption for metallic biomaterials applications is due to their good mechanical properties, such as immobility which makes them suitable for load-bearing implants. The advantages provided by these and the high cost of metals would contribute to the growth of this segment. The advantages provided by these and the high cost of metals would contribute to the growth of this segment. The metallic segment is further sub-segmented into stainless steel, titanium and titanium alloys, cobalt-chrome alloys, silver, gold, and magnesium.

• Ceramic

Bioceramics is a class of materials that are used for repairing or replacing damaged bone tissues. Most clinical applications of bioceramics relate to the repair of the skeletal system, comprising bone, joints, and teeth, and augmenting both hard and soft tissue. Bioceramics can also directly interact with the surrounding tissue, either supporting tissue growth or inducing new tissue regeneration for bioactive ceramics. The ceramic segment is further sub-segmented into calcium phosphate, aluminum oxide, zirconia, calcium sulfate, carbon, and glass.

• Polymeric

Polymeric biomaterials are materials that can be used within physiological environments over long or short periods. Polymeric biomaterials have many advantages due to their unique tailorability of chemical structures and biodegradability, physical properties, and feasibility of being fabricated into medical devices for applications in tissue replacements, drug delivery, and nonviral gene therapy, and cancer therapy. The polymeric segment is further sub-segmented into polymethylmethacrylate (PMMA), polyethylene, polyester, polyvinyl chloride, silicone rubber, nylon, and polyetheretherketone (PEEK).

• Natural

Natural biomaterials are any materials that are taken from plants or animals and used to augment, replace, or repair body tissues and organs. Naturally derived biomaterials are usually applied to replace or restore the structure and function of damaged tissues or organs. They even support cell adhesion, proliferation, migration, and differentiation. The natural segment is further sub-segmented into hyaluronic acid, collagen, gelatin, fibrin, cellulose, chitin, and alginate.

By Application

• Cardiovascular

Cardiovascular diseases are a leading cause of death worldwide. Although surgical and pharmacological interventions improve the quality of life for cardiovascular patients, cheaper and less invasive procedures are always preferable. Additionally, biomaterials exhibit great potential in cardiac repair and regeneration. Their application of injectable biomaterials results in decreased left ventricular dilatation, increased angiogenesis, and preservation of cardiac function. Thus, the growing prevalence of cardiovascular diseases is thus, projected to fuel this market growth during the forecast period.

• Orthopedic

Owing to the increase in adoption of orthopedic biomaterials applications and continuous developments for the introduction of advanced orthopedic implants by market players would lead to the growing demand for implantable devices. Furthermore, unhealthy lifestyles and lack of physical activities are triggering chronic health conditions. Hence, these aforementioned factors are responsible for the increasing preferences for implantable devices among the patient population. Biomaterial-based implants and devices also enhance the quality of our lives by extending the functionality of essential body systems.

• Ophthalmology

Eye implants restore the functionality of the cornea, lens, and vitreous humor when they are damaged. Biomaterials are an important component used to improve and maintain vision and along with that it also used in the treatment of various eye diseases. It includes viscoelastic solutions, contact lenses, eye shields, intraocular lenses, artificial tears, vitreous replacements, correction of corneal curvature and scleral buckling materials.

• Plastic Surgery

Biomaterials are native or synthetic polymers that act as carriers for drug delivery for tissue regeneration. Biomaterials used in plastic surgery are called plastic cosmetic biomaterials. Currently, there are many kinds of biomaterials such as injectable biomaterials and prosthesis materials, and clinically used plastic surgery and their applications are diverse. Moreover, with the rise of three-dimensional printing technology in recent years, the macroscopically more precise and personalized bio-scaffolding materials with microporous structures have made good progress, which is thought to bring new development to biomaterials. For instance, according to the International Society of Aesthetic Plastic Surgery, in the US, around 5.5 million cosmetic procedures were performed in 2021, which has positively influenced the segment growth.

• Wound Healing

The biomedical burden of treating injured organs continues to increase in parallel with the expanding population. The number of implantable devices is preferred due to their proven clinical efficacy and are currently being used as a scaffold for the reconstruction of soft or hard defects. Additionally, they provide various advantages in wound healing applications. They even preserve volume and shape, promote tissue formation, and shorten the time of wound healing. Moreover, many key players through strategic collaborations and acquisitions are expanding their product portfolio for wound healing applications. For instance, in December 2019, Advanced Medical Solutions acquired a surgical biomaterial technologies player Biomatlante. This will help the company to accelerate its commercial success internationally and to develop a wide range of potential applications and indications.

• Tissue Engineering

Technological advancements have made biomaterials more adaptable and have increased their utility in various fields of healthcare, such as bioengineering and tissue engineering. However, the growing demand for smart biomaterials that produce and transfer bioelectric signals similar to native tissues for accurate physiological functions, is expected to accelerate the market growth in the forecast period. Additionally, Piezoelectric are smart materials that play a significant role in tissue engineering. They stimulate the signaling pathways and consequently help to improve tissue regeneration at the impaired site.

• Neurological Disorders

A wide variety of biomaterials are used in treating neurological disorders and to improve functional recovery in the central nervous system (CNS) or gene carriers for the treatment of brain tumors, and for promoting tissue regeneration, neural electrodes for restoration of lost neurological functions, or shunt systems for hydrocephalus. Additionally, the biomaterials used in the central nervous system include silicone, natural polymers, lipids, and synthetic polymers in various forms based on their applications. It is categorized as biodegradable or non-biodegradable, depending on implantation or injection. Moreover, the applications, including drug carriers or tissue scaffolds, require the biomaterials to degrade after their function is fulfilled and along with that the neural electrodes or CNS shunts require the biomaterials to remain functional indefinitely.

• Others

The other segment includes drug delivery systems, and dental. Biomaterials have enhanced oral and injectable drug delivery, the most common modes of drug administration, while also creating new avenues for drug delivery including via pulmonary, transdermal, ocular, and nasal routes. Additionally, it has also improved the delivery and efficacy of a range of pharmaceutical compounds including antibodies, peptides, vaccines, drugs, and enzymes, among others.

Biomaterials Market Regional Analysis

The biomaterials market based on the region has been segmented into North America, Europe, Asia-Pacific, and the Rest of the World.

North America

The presence of key players and increasing demand for implantable devices are fueling the growth of the North America biomaterials market.

North America dominated the biomaterials market owing to the initiatives undertaken by various private and public organizations. These include the National Science Foundation and the National Institute of Standards and Technology, which help to provide knowledge and assistance pertaining to biomaterials usage in biomedical applications. This has also resulted in the expansion of biomaterials adoption in this region. Moreover, factors such as favorable government policies and the presence of several major market players in this region have also contributed to the regional market share.

Europe

An increase in government grants and funding and extensive polymer usage in biomaterials are anticipated to drive market growth in the Europe region.

The European biomaterials market is also growing at a higher rate, which is expected to continue in the future years. The market growth rate is directly influenced by the rising demand for environmentally friendly products in the medical sector. The most prominent application area of the biomaterial market is an orthopedic illness, owing to an increase in the number of orthopedic surgeries requiring implants. Moreover, the countries like Germany and the United Kingdom are investing a significant amount of money in implant imports. This might provide an opportunity for the company to expand its business in these countries.

Asia-Pacific

The growing elderly population and surgical demand are anticipated to drive the market growth in the Asia-Pacific region.

The Asia-Pacific showed the highest CAGR during the forecast period. This is due to the factors like the growing elderly population in this area leads to an increase in bone fractures and surgical demand, propelling market expansion.  India and China are two key countries that contribute significantly to the Asia Pacific's market share. Additionally, the implanted device acceptance, CVD awareness, and improved healthcare infrastructure help to boost the biomaterials market. Further, the existence of a substantial patient pool, especially in rural regions with inadequate healthcare access, and a rising burden of chronic illnesses such as diabetes, cardiovascular disease, and arthritis are helping to propel the market.

Rest of the World

The increase in government funding and the availability of new technologies such as hydrogen scaffolding and decellularized dermal matrixes for grafting are some of the factors driving the growth of the rest of the world biomaterials market. Moreover, the increasing demand for the usage of biomaterials in cardiology wound healing, neurology, and plastic surgery is helping to propel the market. Besides, it will contribute to the market growing at a healthy rate throughout the forecast period. However, adverse reactions to biomaterial implants, inflammation and fracture issues, high cost associated, and difficulties in manufacturing are the major factors off-putting the growth of the rest of the world biomaterials market.

Biomaterials Market Competitive Landscape

The industry players are adopting several business strategies to increase their market presence. They are significantly investing in R&D activities to expand their product portfolio, further driving the biomaterials market. In addition, the market players are adopting several strategic initiatives such as new product launches, contractual agreements, mergers and acquisitions, increasing investments, and partnering with other players to expand their global footprint.

List of companies covered in this report:

• Royal DSM (Netherlands)


• BASF SE (Germany)


• Corbion N.V. (Netherlands)


• Covestro (Germany)


• Invibio Ltd. (UK)


• Carpenter Technology Corporation (US)


• Evonik Industries AG (Germany)


• Berkeley Advanced Biomaterials, Inc. (US)


• CAM Bioceramics BV (Netherlands)


• Celanese Corporation (US)


• Wright Medical Technology, Inc. (US)


• Zimmer Biomet Holdings, Inc. (US)


• Bayer AG (Germany) 


• Collagen Matrix (US)

Biomaterials Market Recent Developments

• In July 2021, Maxx Orthopedics Inc. (US) and Invibio Biomaterial Solutions (UK) together announced the successful initiation of the study and implantation for the total knee arthroplasty (TKA) with the new polymer, PEEK-OPTIMA femoral knee component. This component offers surgeons and patients a femoral component that can correct component to bone material mismatch.


• In January 2021, Evonik (Germany) acquired DURECT Corporation's (US) product line of LACTEL Absorbable Polymers. This acquisition will complement the company's innovation growth field in healthcare solutions and will position the company as a global leader in integrated CDMO for drug delivery solutions.


• In October 2020, In2Bones global Inc. (US) and Invibio (UK) entered into an agreement to start research and development and manufacturing partnership. In this agreement, companies will make major investments and share technical capabilities, intellectual property, clinical data, and labor.


• In September 2020, DSM (Netherlands) collaborated with PBC Biomed (US) to mutually develop novel materials for medical devices. This collaboration will focus on the development of bone adhesives through PBC Biomed's affiliate. Companies aimed at strengthening their respective abilities to help medical device companies for the development of products that will address the increasing trends in medicine.

Biomaterials Market Report Overview

The study covers the existing short-term and long-term market effects. It helps decision-makers to draught short-term and long-term business plans by region. The report covers major regions in North America, Europe, Asia-Pacific, and the Rest of the World. The report analyzes market drivers, restraints, opportunities, challenges, Porter's five forces, value chain, and the impact of COVID-19 on the market.

Study Objectives

• To provide a detailed analysis of the market structure and forecast for the next seven years of the various segments and sub-segments of the biomaterials market


• To provide insights about factors affecting the market growth


• To analyze the biomaterials market based on various factors- price analysis, supply chain analysis, Porter's five force analysis, etc


• To provide historically and forecast revenues of the market segments and sub-segments with respect to four main geographies and their countries- North America, Europe, Asia-Pacific, and the Rest of the World


• To provide a country-level analysis of the market with respect to the current market size and future prospective


• To provide country-level analysis of the market for segments by type, and application


• To provide strategic profiling of key players in the market, comprehensively analyze their core competencies, and draw a competitive market landscape


• To track and analyze competitive developments such as joint ventures, strategic alliances, mergers & acquisitions, new product developments, and R&D in the biomaterials market

Biomaterials Market Segmental Overview:

Global Biomaterials Market, By Type

• Metallic
  
  
  
  • Stainless Steel
  
  
  • Titanium & Titanium Alloys
  
  
  • Cobalt-Chrome Alloys
  
  
  • Silver
  
  
  • Gold
  
  
  • Magnesium
  
  
  • Others
  
  
  
  


• Ceramic
  
  
  
  • Calcium Phosphate
  
  
  • Aluminum Oxide
  
  
  • Zirconia
  
  
  • Calcium Sulfate
  
  
  • Carbon
  
  
  • Glass
  
  
  • Others
  
  
  
  


• Polymeric
  
  
  
  • Polymethylmethacrylate (PMMA)
  
  
  • Polyethylene
  
  
  • Polyester
  
  
  • Polyvinyl Chloride
  
  
  • Silicone Rubber
  
  
  • Nylon
  
  
  • Polyetheretherketone (PEEK)
  
  
  • Others
  
  
  
  


• Natural Biomaterials
  
  
  
  • Hyaluronic Acid
  
  
  • Collagen
  
  
  • Gelatin
  
  
  • Fibrin
  
  
  • Cellulose
  
  
  • Chitin
  
  
  • Alginate
  
  
  • Others
  
  
  
  

Global Biomaterials Market, By Application

• Cardiovascular


• Orthopedic


• Ophthalmology


• Dental


• Plastic Surgery


• Wound Healing


• Tissue Engineering


• Neurological Disorders


• Others

Global Biomaterials Market, By Region

• North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  


• Europe
  
  
  
  • Germany
  
  
  • France
  
  
  • UK
  
  
  • Italy
  
  
  • Spain
  
  
  • Rest of Europe
  
  
  
  


• Asia-Pacific
  
  
  
  • China
  
  
  • Japan
  
  
  • India
  
  
  • Australia
  
  
  • South Korea
  
  
  • Rest of Asia-Pacific
  
  
  
  


• Rest of the World
  
  
  
  • Middle East
  
  
  • Africa
  
  
  • Latin America
  
  
  
  

Intended Audience

• Society for Biomaterials (SFB)The European Society for Biomaterials


• Contract Research Organizations (CROs)


• Research and Development (R&D) Companies


• Biopharmaceutical Companies


• Government & Independent Research Laboratories


• Government and Independent Regulatory Authorities


• Market Research and Consulting Service Providers


• Academic Institutes and Universities