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    Bacillus Subtilis Market

    ID: MRFR/AGR/21367-HCR
    100 Pages
    Tejas Chaudhary
    October 2025

    Bacillus Subtilis Market Research Report By Function (Antibiotic Production, Enzyme Production, Probiotic Supplementation, Other Functions), By Application (Food and Beverage, Pharmaceuticals, Cosmetics, Agriculture, Other Applications), By Strain Type (Wild-Type, Genetically Modified, Other Strain Types), By Formulation (Lyophilized Powder, Liquid Suspension, Granules, Other Formulations) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Bacillus Subtilis Market Infographic
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    Bacillus Subtilis Market Summary

    The Global Bacillus Subtilis Market is projected to grow from 5.80 USD Billion in 2024 to 8.51 USD Billion by 2035.

    Key Market Trends & Highlights

    Bacillus Subtilis Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 3.22% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 8.22 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 5.80 USD Billion, laying a strong foundation for future expansion.
    • Growing adoption of Bacillus Subtilis in agriculture due to its effectiveness as a biofertilizer is a major market driver.

    Market Size & Forecast

    2024 Market Size 5.80 (USD Billion)
    2035 Market Size 8.51 (USD Billion)
    CAGR (2025-2035) 3.55%

    Major Players

    BASF, Novozymes, Chr. Hansen, DSM, Lallemand, Renmatix, AB Enzymes, Lonza, Genomatica, LanzaTech, Hansen Holding A/S, Danisco (now part of DuPont), DSMBiocatalysts Ltd., Codexis, Evonik Industries, Clariant, Amyris

    Bacillus Subtilis Market Trends

    The global market for Bacillus subtilis is experiencing transformative growth, driven by advancements in biotechnology and increasing applications across various industries. One key market driver is the surge in demand from the food industry, where Bacillus subtilis is utilized as a probiotic and natural preservative. The pharmaceutical sector is also contributing to the market's expansion, driven by the development of bio-based pharmaceuticals and the use of Bacillus subtilis in antimicrobial therapies.Emerging opportunities in the market include the exploration of Bacillus subtilis in bioremediation, where its ability to degrade environmental contaminants is gaining attention.

    Additionally, recent trends show a growing focus on sustainable agricultural practices, leading to increased adoption of Bacillus subtilis in the production of biopesticides and biofertilizers. These trends are poised to drive further market expansion in the coming years.

    The increasing adoption of Bacillus subtilis in agricultural practices reflects a growing trend towards sustainable farming and biocontrol methods, which may enhance crop yield while minimizing chemical inputs.

    U.S. Department of Agriculture (USDA)

    Bacillus Subtilis Market Drivers

    Rising Demand for Probiotics

    The increasing consumer awareness regarding gut health and the benefits of probiotics contributes to the growth of the Global Bacillus Subtilis Market Industry. Probiotics are recognized for their role in enhancing digestive health and boosting the immune system. As consumers seek natural and effective solutions for health issues, the demand for Bacillus Subtilis as a probiotic strain is likely to rise. This trend is reflected in the projected market value, which is expected to reach 5.8 USD Billion in 2024. The growing inclination towards preventive healthcare further supports this demand, indicating a robust future for the industry.

    Increasing Use in Animal Feed

    The incorporation of Bacillus Subtilis in animal feed is gaining traction, significantly influencing the Global Bacillus Subtilis Market Industry. This microorganism is known to improve gut health in livestock, leading to better nutrient absorption and overall animal performance. As the livestock industry seeks to enhance productivity while adhering to stricter regulations on antibiotic use, the demand for natural additives like Bacillus Subtilis is likely to rise. This trend not only supports animal health but also aligns with consumer preferences for sustainably produced animal products, thereby reinforcing the market's growth trajectory.

    Expansion in Agricultural Applications

    Bacillus Subtilis is increasingly utilized in agriculture as a biofertilizer and biopesticide, which is a key driver for the Global Bacillus Subtilis Market Industry. The shift towards sustainable farming practices has led to a heightened interest in biological solutions that enhance crop yield while minimizing chemical inputs. This trend aligns with global agricultural policies promoting eco-friendly practices. The market is projected to grow significantly, with estimates suggesting a value of 8.22 USD Billion by 2035. The adoption of Bacillus Subtilis in agriculture not only supports crop health but also contributes to soil fertility, making it a vital component of modern farming.

    Technological Advancements in Fermentation

    Innovations in fermentation technology are enhancing the production efficiency of Bacillus Subtilis, thereby driving the Global Bacillus Subtilis Market Industry. Advanced fermentation techniques allow for higher yields and reduced production costs, making Bacillus Subtilis more accessible for various applications. These technological improvements are crucial as they enable manufacturers to meet the growing demand for this microorganism across sectors such as food, pharmaceuticals, and agriculture. As a result, the market is expected to experience a compound annual growth rate of 3.22% from 2025 to 2035, indicating a sustained interest in Bacillus Subtilis as a versatile and beneficial organism.

    Growing Interest in Natural Food Preservatives

    The rising consumer preference for natural food preservatives is propelling the Global Bacillus Subtilis Market Industry. Bacillus Subtilis is recognized for its ability to produce antimicrobial compounds that can extend the shelf life of food products without the use of synthetic additives. This shift towards clean label products is becoming increasingly important as consumers demand transparency in food ingredients. The market's expansion is indicative of a broader trend towards healthier eating habits, with Bacillus Subtilis positioned as a key player in the natural food preservation sector. This trend is expected to contribute to the overall growth of the market in the coming years.

    Market Segment Insights

    Bacillus Subtilis Market Function Insights  

    The Function segment of the Bacillus Subtilis Market consists of Antibiotic Production, Enzyme Production, Probiotic Supplementation and Other Function divisions. In 2023, the antibiotic production segment holds the largest market share, which will continue to dominate in the future. This is due to an increasing number of infectious diseases and rising need for effective antibiotics. Bacillus Subtilis is the origin of two common antibiotics, bacitracin and polymyxin, which are used to treat varying types of bacterial infections, such as cutaneous and ocular infections and respiratory tract infections.

    Another significant segment is enzyme production, as Bacillus Subtilis-derived enzymes play a vital role in a wide range of industries. The food, beverage, detergent, and pharmaceutical industries, for example, use Bacillus Subtilis enzymes. The latter industry uses Bacillus Subtilis-derived proteases in washing powders and Bacillus Subtilis-derived amylases in brewing. Probiotic Supplementation is another revolutionary segment, as the need for Bacillus Subtilis-based supplements for digestion, the immune system, and the overall health of the consumer is steadily increasing.

    The Bacillus Subtilis Other Function variant may act as a biocontrol agent, feed additive, or soil amendment. The former is used to reduce plant diseases and purvey, and the latter is used to improve soil fertility and plant growth, while feed additives help livestock grow faster and remain healthy. This segment is projected to grow steadily in the future due to the steady need for Bacillus Subtilis in these areas. Overall, the function segment of the Bacillus Subtilis Market will grow steadily in the future as the need for Bacillus Subtilis will increase steadily in these areas.

    Increasing infectious diseases, the need to relieve them, the steady need for Bacillus Subtilis products to improve the health and well-being of humans and the increased use of this product in industry are factors that will stimulate future market growth.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Bacillus Subtilis Market Application Insights  

    On the whole, it is possible to note that the application segment contributes extensively to the development of the Bacillus Subtilis Market revenue. Among the core applications, the Food and Beverage segment was identified as the leading one in 2023 owing to the growing popularity of Bacillus Subtilis as a natural preservative and enhancer for food flavors.

    Furthermore, while the benefits of the utilization of this strain for the production of medicine have remained limited, the Pharmaceuticals segment is likely to grow in terms of its significance in the course of the specified period due to the increasing proliferation of persistent diseases and the emergence of new drugs.In addition, there has been a rise in the cosmetics segment, in which the application of this probiotic is targeted at the creation of antiaging and skin-conditioning agents. Finally, agricultural segment, including biopesticides and biofertilizers is becoming increasingly popular due to the considerable increase in the promotion of environment-friendly farming.

    Bacillus Subtilis Market Strain Type Insights  

    The Bacillus Subtilis Market revenue is projected to grow from USD 4.4 billion in 2023 to USD 6 billion in 2032, at a CAGR of 3.8% during the forecast period. The market growth is attributed to the increasing demand for Bacillus subtilis in various industries, including food, pharmaceuticals, and agriculture. Based on the strain type, the market is segmented into wild-type, genetically modified, and other strain types. The genetically modified strain type segment is expected to witness the highest growth during the forecast period due to the increasing adoption of genetically modified microorganisms in various industrial applications.

    The wild-type strain type accounted for the largest share of the Bacillus Subtilis Market in 2023 and is expected to continue its dominance throughout the forecast period. Wild-type strains are naturally occurring and have been used in industrial applications for centuries. They are generally regarded as safe (GRAS) by regulatory authorities, making them a preferred choice for many industries. Genetically modified strains of Bacillus subtilis are created using genetic engineering techniques to enhance their specific properties or introduce new functionalities.These strains can be designed to produce specific enzymes, proteins, or other molecules that are valuable in various industrial processes.

    The use of genetically modified strains is expected to grow as industries seek to optimize production efficiency and develop new products. Other strain types of Bacillus subtilis include mutant strains, recombinant strains, and encapsulated strains. These strains have been developed for specific applications and offer unique advantages in terms of stability, productivity, or other characteristics. The demand for these specialized strains is expected to increase as industries explore new applications for Bacillus subtilis.

    Bacillus Subtilis Market Formulation Insights  

    Bacillus Subtilis Market segmentation by formulation reveals a diverse landscape with varying market shares and growth dynamics. Lyophilized Powder formulation held the dominant position in 2023, capturing approximately 45% of the Bacillus Subtilis Market revenue. Its stability, ease of storage, and prolonged shelf life make it a preferred choice for applications in pharmaceuticals, food and beverages, and agriculture. Liquid Suspension formulation followed closely, accounting for around 30% of the market share.

    It offers advantages such as rapid absorption and ease of administration, making it suitable for use in animal feed and veterinary applications.Granules formulation, with its cost-effectiveness and ease of handling, held a market share of approximately 18% in 2023. It is primarily used in agriculture and horticulture for soil amendment and microbial inoculants. Other Formulations, including capsules, tablets, and films, collectively accounted for the remaining 7% market share. These formulations cater to specific applications and offer advantages such as targeted delivery, controlled release, and enhanced bioavailability.

    As the Bacillus Subtilis Market continues to expand, the demand for diverse formulations is expected to drive market growth, offering opportunities for manufacturers to innovate and cater to evolving customer needs.

    Get more detailed insights about Bacillus Subtilis Market

    Regional Insights

    The regional landscape of the Bacillus Subtilis Market exhibits distinct market dynamics and growth patterns across various geographical regions. North America holds a significant market share due to the presence of well-established pharmaceutical and biotechnology industries. Europe follows closely, driven by rising demand from the food and beverage sector. The Asia-Pacific region is projected to witness robust growth in the coming years, fueled by increasing consumption of probiotics and supplements. South America and MEA are emerging markets with potential for growth as awareness about the health benefits of Bacillus Subtilis increases.

    Bacillus Subtilis Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Bacillus Subtilis Market industry's major players are engaged all the time to get a competitive edge by concentrating investments on research and development, their portfolio of product extensions, and getting into strategic partnerships. A Leading Bacillus Subtilis Market player is primarily working on developing innovative products that take into account the needs of the customers. Apart from that, they are seeking to make their presence in emerging markets larger as growing demand for Bacillus Subtilis. 

    The demand for Bacillus Subtilis Market is increasing due to the development of pharmaceuticals, food and beverages, and agriculture. Moreover, the other key factors include growing demand for the Bacillus Subtilis Market. On the other hand, competitive rivalry in the Bacillus Subtilis Market is going to increase with the emergence of new players and the presence of old players who are focused on expanding market share.One of the highest competitors in the Bacillus Subtilis Market is BASF. Enzymes, probiotics, and feed additives are the key products that are provided by the company and have the form of Bacillus Subtilis.

    BASF refers to the powerful R capabilities and product quality. 

    The presence of the company is global, and the customer range is broad. Novozymes is another competitor of the Bacillus Subtilis Market. Monogastric, ruminant, industrial, and supplement are the key products. Novozymes has a strong focus on innovation and sustainability. Novozymes has a broad range of customers and a global presence. Moreover, the key features of Novozymes' products are customer satisfaction and high quality.

    Key Companies in the Bacillus Subtilis Market market include

    Industry Developments

    The Bacillus Subtilis Market is anticipated to reach a value of USD 7.4 billion by 2032, expanding at a CAGR of 3.55% over the forecast period (2024-2032). Rising demand for Bacillus subtilis in the production of enzymes, pharmaceuticals, and food additives is driving market growth.Recent developments in the market include: In 2023, BASF launched a new strain of Bacillus subtilis, Bactoferm PB6, for use in animal feed. This strain is designed to improve gut health and animal performance. In 2022, Chr. Hansen acquired the Bacillus subtilis business of Novozymes. This acquisition strengthens Chr. Hansen's position in the probiotics market.Key industry players include BASF Chr.

    Hansen DSM Novozymes Lallemand

    Future Outlook

    Bacillus Subtilis Market Future Outlook

    The Bacillus Subtilis Market is projected to grow at a 3.55% CAGR from 2025 to 2035, driven by increasing demand in agriculture, biopharmaceuticals, and food industries.

    New opportunities lie in:

    • Develop innovative formulations for agricultural applications to enhance crop yield.
    • Invest in R&D for Bacillus Subtilis-based probiotics targeting gut health.
    • Expand distribution channels in emerging markets to capture new customer segments.

    By 2035, the Bacillus Subtilis Market is expected to demonstrate robust growth and increased market penetration.

    Market Segmentation

    Bacillus Subtilis Market Function Outlook

    • Food and Beverage
    • Pharmaceuticals
    • Cosmetics
    • Agriculture
    • Other Applications

    Bacillus Subtilis Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Bacillus Subtilis Market Application Outlook

    • Wild-Type
    • Genetically Modified
    • Other Strain Types

    Bacillus Subtilis Market Formulation Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Bacillus Subtilis Market Strain Type Outlook

    • Lyophilized Powder
    • Liquid Suspension
    • Granules
    • Other Formulations

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024  5.80(USD Billion)
    Market Size 2025 6.00(USD Billion)
    Market Size 2035 8.51 (USD Billion)
    Compound Annual Growth Rate (CAGR) 3.55% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2023
    Market Forecast Units USD Billion
    Key Companies Profiled Renmatix, AB Enzymes, Lonza, Genomatica ,LanzaTech, Chr. Hansen Holding A/S, Danisco (now part of DuPont), DSM, Biocatalysts Ltd., Codexis, Evonik Industries, Novozymes, Clariant, BASF, Amyris
    Segments Covered Function, Application, Strain Type, Formulation, Regional
    Key Market Opportunities Biopesticides industry expansion Probiotics and supplements demand growth. Healthcare applications advancements
    Key Market Dynamics 1 Growing demand for food and beverage2 Increasing adoption of pharmaceuticals3 Rising applications in agriculture
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What was at a the expected Market Was at a Bacillus Subtilwas at a in 2024?

    The Bacillus Subtilwas at a Market 5.80 Billion USD by 2024

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