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Periodontal Therapeutics Market Size, Growth Research Report By Therapeutic Class (Antimicrobial Agents, Anti-inflammatory Agents, Regenerative Agents, Desensitizing Agents), By Application (Periodontitis, Gingivitis, Peri-implantitis, Other Periodontal Diseases), By Formulation Type (Gel, Spray, Oral Rinse, Tablet, Injectable), By Distribution Channel (Hospitals, Dental Clinics, Online Pharmacy, Retail Pharmacy) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Competitor Industry Analysis and T


ID: MRFR/HC/5100-HCR | 200 Pages | Author: Rahul Gotadki| July 2025

Periodontal Therapeutic Market Summary

As per MRFR Analysis, the Periodontal Therapeutics Market was valued at 3.15 USD Billion in 2023 and is projected to grow to 5.0 USD Billion by 2035, reflecting a CAGR of 3.94% from 2025 to 2035. The market is driven by the increasing prevalence of periodontal diseases, heightened awareness of oral health, and advancements in dental technologies.

Key Market Trends & Highlights

The Global Periodontal Therapeutics Market is witnessing significant trends driven by various factors.

  • Approximately 47.2% of adults aged 30 years and older in the U.S. have some form of periodontal disease.
  • Antimicrobial Agents are expected to generate 1.31 USD Billion in 2024, growing to 1.95 USD Billion by 2035.
  • North America is projected to reach 2.04 USD Billion by 2035, leading the market.
  • Government funding for oral healthcare has increased by around 15% to improve access to treatments.

Market Size & Forecast

2023 Market Size: USD 3.15 Billion
2024 Market Size: USD 3.27 Billion
2035 Market Size: USD 5.0 Billion
CAGR (2025-2035): 3.94%
Largest Regional Market Share in 2024: North America.

Major Players

Key players include Pfizer, Merck and Co, Johnson and Johnson, Sun Pharmaceutical Industries, and Dentsply Sirona.

Key Periodontal Therapeutics Market Trends Highlighted


The Periodontal Therapeutics Market is experiencing several significant trends driven by increasing awareness about oral health and advancements in dental care technologies. One key market driver is the rising prevalence of periodontal diseases worldwide, which is pushing both patients and healthcare providers to seek effective therapeutic solutions. 


Governments and health organizations globally are emphasizing preventive dental care, thus promoting regular check-ups and the adoption of causal and clinical treatments for periodontal health, increasing demand for therapeutic options. Opportunities in the periodontal therapeutics sector are expanding due to the incorporation of new technologies, such as laser therapy and regenerative treatments.

These advanced solutions are gaining traction as they offer minimally invasive options for patients, improving treatment outcomes. Additionally, there is a growing inclination towards natural and bio-based products, creating space for innovative therapeutic solutions that are perceived as safer and more effective. Recent trends include the shift towards personalized dentistry, where treatments are tailored based on individual patient needs and genetic backgrounds. 


This trend aligns with broader movements in healthcare that prioritize patient-centered care. Moreover, there is an increase in collaborations among dental practitioners, researchers, and pharmaceutical companies to develop new therapeutic agents and methods for managing periodontal diseases.Overall, the Periodontal Therapeutics Market is adapting to meet the needs of a changing healthcare landscape, reflecting a commitment to improving oral health on a global scale.


Global Periodontal Therapeutics Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Periodontal Therapeutics Market Drivers


Increase in Prevalence of Periodontal Diseases Globally


The increasing global incidence of periodontal diseases is a major driver of the Periodontal Therapeutics Market Industry. According to World Health Organization (WHO) data, approximately 50% of adults aged 30 and older have some form of periodontal disease, with these figures expected to rise significantly due to factors such as aging populations, poor oral hygiene, and increased consumption of processed foods. Furthermore, the Federation Dentaire Internationale has said that periodontal disease prevalence might reach up to 80% in persons 65 and older.

This frightening tendency needs enhanced therapeutic options and treatments, hence promoting market expansion. Furthermore, notable organizations such as the American Academy of Periodontology (AAP) have emphasized the importance of raising awareness and improving treatment protocols, which is expected to increase the penetration and adoption of periodontal therapies in both developed and developing countries.


Technological Advancements in Dental Therapies


The Periodontal Therapeutics Market Industry is notably driven by technological innovations that enhance treatment efficacy and patient outcomes. Research and Development (R&D) investments from leading companies in the oral health sector have resulted in advanced treatment modalities, including minimally invasive procedures and biologics. For instance, the introduction of regenerative therapies and laser treatments has revolutionized periodontal care.

The American Dental Association (ADA) has reported a 30% increase in the usage of laser technology within the last five years, supported by clinical evidence showing significant improvements in healing times and comfort for patients. As these advanced technologies gain acceptance among dental professionals, the demand for periodontal therapeutics is expected to escalate.


Growing Awareness about Oral Health


Awareness regarding the importance of oral health has been on the rise, significantly impacting the Periodontal Therapeutics Market Industry. Initiatives led by organizations such as the Centers for Disease Control and Prevention (CDC) have implemented nationwide campaigns aimed at educating the public about the impacts of oral diseases on overall health. Recent studies indicate that more than 70% of adults now acknowledge the link between oral health and systemic diseases, which promotes a proactive approach to dental care.

The increased focus on preventative care and early intervention has led to a heightened demand for periodontal treatments, pushing market growth further as individuals seek expert periodontal care to mitigate potential health risks associated with untreated periodontal disease.


Periodontal Therapeutics Market Segment Insights


Periodontal Therapeutics Market Therapeutic Class Insights   


The Periodontal Therapeutics Market is projected to experience substantial growth within the Therapeutic Class segment, estimated to reach a valuation of 3.27 USD Billion by 2024 and further increasing to 5.0 USD Billion by 2035. This growth trajectory highlights a compound annual growth rate of 3.94 from 2025 to 2035. Within this broad classification, the market is divided into various key categories that play crucial roles in periodontal therapies. The Antimicrobial Agents category is particularly significant, projected to be valued at 1.3 USD Billion in 2024 and anticipated to expand to 1.9 USD Billion by 2035, indicating its major position in preventing and managing infections associated with periodontal diseases.

This reflects the necessity for effective infection control in periodontal therapy, contributing to its dominance in market share. The Anti-inflammatory Agents are equally vital, with a valuation expected to rise from 0.95 USD Billion in 2024 to 1.4 USD Billion in 2035. Their importance lies in their ability to reduce inflammation, which is a common symptom associated with periodontal issues, thereby enhancing overall patient outcomes. The Regenerative Agents, although smaller in market size, with a projected increase from 0.77 USD Billion in 2024 to 1.1 USD Billion by 2035, are significant as they help in tissue regeneration, addressing a critical aspect of periodontal treatment.

Lastly, the Desensitizing Agents segment is valued at 0.25 USD Billion in 2024 and is expected to grow to 0.6 USD Billion by 2035. Although it holds the smallest share, its function in alleviating patient discomfort during treatments highlights its relevance in providing comprehensive care. The diverse range of agents within the Therapeutic Class, each catering to specific needs of periodontal treatment, underlines the complexity and multifaceted nature of the Periodontal Therapeutics Market. Growth drivers for this market include an increasing prevalence of periodontal diseases driven by lifestyle changes and growing awareness regarding oral health, as well as ongoing Research and Development initiatives aimed at improving therapeutic efficacy.

However, challenges like economic constraints and fluctuating healthcare budgets may impact market growth. Nevertheless, the continued innovation in therapeutic solutions represents significant opportunities in a market poised for expansion.  Overall, the segmentation within the Therapeutic Class reflects a strategic approach towards addressing diverse patient needs and improving treatment protocols in the realm of periodontal care.


Periodontal Therapeutics Market Therapeutic Class Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Periodontal Therapeutics Market Application Insights   


The Periodontal Therapeutics Market focuses significantly on various applications, particularly addressing conditions such as Periodontitis, Gingivitis, Peri-implantitis, and Other Periodontal Diseases. As of 2024, the complete market valuation is expected to reach 3.27 billion USD, projecting growth that reflects the increasing prevalence of periodontal diseases globally. Periodontitis, known for its profound impact on oral health, requires effective management strategies, contributing to a majority holding in treatment demand. Meanwhile, Gingivitis poses a common yet manageable condition that necessitates ongoing therapeutic innovations.

Peri-implantitis, associated with the complications of dental implants, sees a rising emphasis on specialized treatments due to its complex nature and implications on overall oral health. Other Periodontal Diseases encompass a range of ailments that continue to drive advancements in the Periodontal Therapeutics Market industry, creating ample opportunities for growth. With ongoing investment in research and development and an increasing focus on preventive care, the market is positioned to address evolving healthcare needs effectively. The overall growth trajectory is driven by heightened awareness of periodontal health, improved accessibility to treatment options, and technological advancements in therapeutic approaches.


Periodontal Therapeutics Market Formulation Type Insights   


The Periodontal Therapeutics Market, focusing on the Formulation Type segment, is on a growth trajectory reflecting an increasing demand for effective periodontal disease management. In 2024, the market reached a value of 3.27 billion USD, demonstrating the significance of various formulations in offering innovative treatment solutions. The segmentation of this market includes Gel, Spray, Oral Rinse, Tablet, and Injectable options, each playing a crucial role in addressing patient needs. Gels and sprays are particularly popular due to their ease of use and targeted delivery, allowing for localized treatment of periodontal conditions.

Oral rinses have gained traction for their convenience and efficacy in maintaining oral hygiene, complementing other treatment modalities. Tablets offer an alternative, proving advantageous for patient compliance, while injectables represent a more advanced therapeutic approach for managing severe periodontal cases. As consumer awareness about gum health increases and technological advancements in formulation continue, the Periodontal Therapeutics Market is poised to flourish, showcasing promising growth opportunities driven by diverse and effective formulations catering to various patient preferences and clinical applications.


Periodontal Therapeutics Market Distribution Channel Insights   


The Periodontal Therapeutics Market is witnessing a notable distribution across various channels, with a projected valuation of 3.27 USD Billion in 2024, showcasing significant growth momentum. Within the distribution channel segment, Hospitals and Dental Clinics play critical roles, often being the primary touchpoints for patients seeking advanced periodontal treatments. These settings provide access to specialized care and equipment, which is essential for effective diagnosis and treatment. Online Pharmacies have emerged as a crucial avenue for patients, offering convenience and access to a broader range of therapeutic products, especially in regions with limited physical pharmacy access.

Retail Pharmacies also contribute significantly to the market, serving as an easily accessible source for over-the-counter treatments while facilitating patient education about periodontal health. Each of these channels plays a vital role in the Periodontal Therapeutics Market's segmentation, highlighting the diverse healthcare ecosystem that supports periodontal care globally. The interplay between these distribution channels supports the overall growth and demand for periodontal therapeutics, reflecting evolving consumer preferences and healthcare delivery models.


Periodontal Therapeutics Market Regional Insights   


The Periodontal Therapeutics Market exhibits substantial segmentation by region, reflecting varying market dynamics across different areas. In 2024, North America leads with a valuation of 1.149 USD Billion, expected to grow to 1.875 USD Billion by 2035, highlighting its majority holding in the market due to advanced healthcare infrastructure and emphasis on dental care. Europe follows with a valuation of 0.766 USD Billion in 2024, projected to reach 1.25 USD Billion, indicating strong growth potential attributed to rising awareness regarding periodontal diseases.

The Asia Pacific region is valued at 0.728 USD Billion and aims to increase to 1.125 USD Billion, showcasing growing healthcare investments and a more extensive patient base. South America's valuation stands at 0.230 USD Billion in 2024, with growth anticipated to 0.417 USD Billion, reflecting increasing healthcare access. Meanwhile, the Middle East and Africa, valued at 0.398 USD Billion, are expected to decline to 0.333 USD Billion due to economic challenges, yet remains significant for its emerging markets. These insights illustrate the diverse growth opportunities and challenges across regions within the Periodontal Therapeutics Market, characterized by differing needs and advancements in dental health awareness.


Periodontal Therapeutics Market Regional Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Periodontal Therapeutics Market Key Players and Competitive Insights


The Periodontal Therapeutics Market is characterized by a dynamic competitive landscape, as it encompasses various stakeholders working diligently to innovate and enhance gum disease treatment solutions. This market includes pharmaceutical firms, biotechnology companies, and dental product manufacturers who are focused on addressing the increasing prevalence of periodontal diseases worldwide. The competitive insights revolve around product launches, research and development initiatives, strategic collaborations, and market expansion efforts. As the awareness regarding oral health continues to rise and preventive measures gain traction, the market is expected to experience substantial growth, with rapid advancements in therapeutic offerings and technology integrations being pivotal to the competitive strategies employed by players in the field.

Astellas Pharma has established itself as a significant player in the Periodontal Therapeutics Market, focusing on innovative therapies to combat periodontal diseases. With a commitment to research and development, Astellas Pharma has a strong portfolio that emphasizes effective treatment options and improved patient outcomes. The company benefits from a well-established global presence, allowing it to leverage partnerships with dental professionals and healthcare networks. Astellas Pharma's strengths lie in its ability to navigate regulatory pathways efficiently and to adapt its therapeutic strategies in response to evolving market demands and trends, thereby ensuring relevance and responsiveness in the competitive landscape of periodontal therapeutics.

P&G Healthcare has a robust position within the Periodontal Therapeutics Market, primarily due to its extensive expertise in consumer health products. The company offers a range of products focused on periodontal health, including advanced oral care solutions that target gum disease prevention and treatment. P&G Healthcare's key strengths include a strong brand reputation and a well-distributed product line that resonates with consumers worldwide. Their strategic focus on research and development allows for innovative product enhancements and new introductions to the market. Additionally, P&G Healthcare has engaged in various mergers and acquisitions that aim to bolster its portfolio and increase market penetration, further solidifying its presence in the global arena. Through these strategic initiatives, P&G Healthcare continues to enhance its capabilities and offerings in the periodontal therapeutics sector.


Key Companies in the Periodontal Therapeutics Market Include



  • Astellas Pharma

  • P&G Healthcare

  • Sunstar

  • PerioSciences

  • Johnson & Johnson

  • Herapha

  • Crosstex International

  • Henkel

  • MediDent

  • ColgatePalmolive

  • 3M

  • Dentsply Sirona

  • GlaxoSmithKline

  • Procter & Gamble

  • Kerr Corporation


Periodontal Therapeutics Market Industry Developments


The Periodontal Therapeutics Market has witnessed significant developments recently, particularly with advancements in product offerings and therapeutic approaches. In September 2023, Astellas Pharma launched a new therapeutic product aimed at improving oral health outcomes, which garnered positive attention in the market. Growth has been observed in companies such as Colgate-Palmolive and Procter and Gamble, which have reported increased revenues tied to their periodontal care lines, indicating rising consumer demand for oral health products. Merger and acquisition activity has also been notable; in August 2023, Dentsply Sirona acquired a leading provider of dental hygiene products, enhancing its portfolio in the periodontal sector.


Additionally, Sunstar has expanded its global reach by forming strategic partnerships aimed at improving access to periodontal care in developing markets, contributing to overall market growth. Overall, the heightened investments in Research and Development by major players like Johnson and Johnson and 3M are reshaping the competitive landscape, focusing on innovative therapies that align with current trends, emphasizing preventive dental care and disease management. The continued focus on enhancing aesthetic and functional oral health will likely sustain the momentum in the Periodontal Therapeutics Market over the coming years.


Periodontal Therapeutics Market Segmentation Insights


Periodontal Therapeutics Market Therapeutic Class Outlook



  • Antimicrobial Agents

  • Anti-inflammatory Agents

  • Regenerative Agents

  • Desensitizing Agents


Periodontal Therapeutics Market Application Outlook



  • Periodontitis

  • Gingivitis

  • Peri-implantitis

  • Other Periodontal Diseases


Periodontal Therapeutics Market Formulation Type Outlook



  • Gel

  • Spray

  • Oral Rinse

  • Tablet

  • Injectable


Periodontal Therapeutics Market Distribution Channel Outlook



  • Hospitals

  • Dental Clinics

  • Online Pharmacy

  • Retail Pharmacy


Periodontal Therapeutics Market Regional Outlook



  • North America

  • Europe

  • South America

  • Asia Pacific

  • Middle East and Africa

Report Attribute/Metric Details
Market Size 2023 3.15(USD Billion)
Market Size 2024 3.27(USD Billion)
Market Size 2035 5.0(USD Billion)
Compound Annual Growth Rate (CAGR) 3.94% (2025 - 2035)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Billion
Key Companies Profiled Astellas Pharma, P&G Healthcare, Sunstar, PerioSciences, Johnson & Johnson, Herapha, Crosstex International, Henkel, MediDent, ColgatePalmolive, 3M, Dentsply Sirona, GlaxoSmithKline, Procter & Gamble, Kerr Corporation
Segments Covered Therapeutic Class, Application, Formulation Type, Distribution Channel, Regional
Key Market Opportunities Growing geriatric population, Increasing prevalence of periodontal diseases, Advancements in treatment technologies, Rising awareness of oral health, Expansion of dental insurance coverage
Key Market Dynamics Rising prevalence of periodontal diseases, Increasing demand for oral health products, Growing geriatric population, Advancements in therapeutic technologies, Increased awareness of dental hygiene
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The Periodontal Therapeutics Market was valued at 3.27 billion USD in 2024.

By 2035, the Periodontal Therapeutics Market is projected to reach 5 billion USD.

The expected CAGR for the Periodontal Therapeutics Market from 2025 to 2035 is 3.94%.

North America held the largest market share, valued at approximately 1.149 billion USD in 2024.

The market size for Antimicrobial Agents in the Periodontal Therapeutics Market is expected to be 1.3 billion USD in 2024.

The market size for Anti-inflammatory Agents is projected to grow to 1.4 billion USD by 2035.

Key players in the Periodontal Therapeutics Market include companies like Astellas Pharma, P&G Healthcare, and Johnson & Johnson.

Europe's market is expected to grow to approximately 1.25 billion USD by 2035.

Regenerative Agents are expected to show significant growth, increasing from 0.77 billion USD in 2024 to 1.1 billion USD in 2035.

The market is witnessing growth driven by advancements in treatment technologies and an increasing awareness of oral health.

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