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US Gallstone Market

ID: MRFR/Pharma/17464-HCR
100 Pages
Garvit Vyas
October 2025

US Gallstone Market Research Report By Cause (Cholesterol stone, Bilirubin, Concentrated bile, Others), By Diagnosis (Ultrasound, Abdomal CT scan, Gallbladder radionuclide scan, Blood test, Others) and By Treatment (Open cholecystectomy, Laparoscopic cholecystectomy, Medication, Others) - Forecast to 2035

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US Gallstone Market Infographic
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US Gallstone Market Summary

As per MRFR analysis, the US gallstone market Size was estimated at 75.6 USD Million in 2024. The US gallstone market is projected to grow from 81.68 USD Million in 2025 to 177.03 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 8.04% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US gallstone market is experiencing growth driven by technological advancements and increasing awareness.

  • Rising awareness and education about gallstone prevention and treatment options are shaping consumer behavior.
  • Technological advancements in treatment methods are enhancing patient outcomes and driving market growth.
  • The largest segment in the US gallstone market is the surgical treatment segment, while the fastest-growing segment is the minimally invasive procedures segment.
  • Key market drivers include the increasing incidence of gallstones and advancements in minimally invasive procedures.

Market Size & Forecast

2024 Market Size 75.6 (USD Million)
2035 Market Size 177.03 (USD Million)
CAGR (2025 - 2035) 8.04%

Major Players

Boston Scientific (US), Medtronic (US), Johnson & Johnson (US), Baxter International (US), Stryker Corporation (US), Abbott Laboratories (US), Cook Medical (US), Olympus Corporation (JP), Fujifilm Holdings Corporation (JP)

US Gallstone Market Trends

The gallstone market is currently experiencing notable shifts driven by various factors. Increasing awareness regarding gallstone-related health issues has led to a rise in diagnostic procedures and treatment options. This heightened awareness is likely influenced by educational campaigns and improved access to healthcare services. Furthermore, advancements in medical technology are facilitating more effective treatment methods, which may enhance patient outcomes and satisfaction. As a result, healthcare providers are increasingly adopting minimally invasive techniques, which could potentially reshape the treatment landscape. In addition, demographic changes, particularly the aging population, appear to be contributing to the growth of the gallstone market. Older individuals are generally at a higher risk for developing gallstones, which may lead to increased demand for both surgical and non-surgical interventions. Moreover, lifestyle factors such as diet and obesity are also significant contributors to gallstone formation, prompting healthcare professionals to focus on preventive measures. Overall, the gallstone market seems poised for continued expansion as awareness, technology, and demographic trends converge to influence treatment approaches and patient care.

Rising Awareness and Education

There is a growing emphasis on educating the public about gallstone health risks. Campaigns aimed at increasing awareness are likely leading to more individuals seeking medical advice and undergoing diagnostic tests. This trend may result in earlier detection and treatment, ultimately improving patient outcomes.

Technological Advancements in Treatment

Innovations in medical technology are transforming treatment options available for gallstones. Minimally invasive procedures are becoming more prevalent, which may enhance recovery times and reduce complications. This shift towards advanced techniques could significantly impact patient preferences and healthcare practices.

Demographic Shifts and Lifestyle Factors

The aging population in the US is contributing to a higher incidence of gallstones. As older adults are more susceptible to this condition, there is an increasing demand for effective treatment solutions. Additionally, lifestyle choices, including diet and obesity, are influencing the prevalence of gallstones, prompting a focus on preventive strategies.

US Gallstone Market Drivers

Rising Healthcare Expenditure

The gallstone market is benefiting from the rising healthcare expenditure in the US. With healthcare spending projected to reach $4.1 trillion by 2025, there is an increasing allocation of funds towards the treatment of various medical conditions, including gallstones. This financial commitment allows for better access to diagnostic tools, treatment options, and patient education programs. As patients become more aware of their treatment options, the demand for gallstone-related services is likely to increase. Furthermore, the expansion of insurance coverage for gallstone treatments may also contribute to market growth, as more individuals seek medical assistance for their conditions.

Increasing Incidence of Gallstones

The gallstone market is experiencing growth due to the rising incidence of gallstones among the population. Studies indicate that approximately 10-15% of adults in the US are affected by gallstones, with higher prevalence in women and individuals over 40 years of age. This increasing incidence is likely to drive demand for diagnostic and therapeutic services related to gallstones. As healthcare providers focus on managing this condition, the gallstone market is expected to expand, with a projected market value reaching $2 billion by 2026. The growing number of patients seeking treatment will necessitate advancements in medical technologies and surgical procedures, further propelling the market forward.

Growing Focus on Preventive Healthcare

The gallstone market is also influenced by the growing focus on preventive healthcare measures. As awareness of lifestyle-related health issues increases, more individuals are adopting healthier diets and exercise regimens to mitigate the risk of developing gallstones. This trend is likely to lead to a decrease in the incidence of gallstones over time, but it also creates a demand for educational resources and preventive treatments. Healthcare providers are increasingly offering programs aimed at educating patients about gallstone prevention, which may contribute to market growth. The emphasis on preventive care is expected to shape the future landscape of the gallstone market.

Technological Innovations in Diagnostics

Technological innovations in diagnostics are playing a crucial role in the gallstone market. The introduction of advanced imaging techniques, such as ultrasound and MRI, has improved the accuracy of gallstone detection. These technologies enable healthcare professionals to diagnose gallstones more effectively, leading to timely interventions and better patient outcomes. As diagnostic tools continue to evolve, the market is likely to see an increase in the number of patients diagnosed and treated for gallstones. The integration of artificial intelligence in imaging analysis may further enhance diagnostic capabilities, potentially increasing the market size as more individuals seek early detection and treatment.

Advancements in Minimally Invasive Procedures

The gallstone market is significantly influenced by advancements in minimally invasive surgical techniques. Procedures such as laparoscopic cholecystectomy have gained popularity due to their reduced recovery times and lower complication rates compared to traditional surgeries. As more healthcare facilities adopt these techniques, patient outcomes improve, leading to increased patient satisfaction and a higher volume of surgeries performed. The market for gallstone treatment is projected to grow as these innovative procedures become more widely available. In 2025, the market for minimally invasive gallstone surgeries is expected to account for over 60% of the total surgical procedures, indicating a shift towards less invasive treatment options.

Market Segment Insights

By Cause: Cholesterol Stones (Largest) vs. Bilirubin (Fastest-Growing)

In the US gallstone market, the distribution of market share among the various causes reveals that cholesterol stones dominate with a significant percentage, showcasing their prevalence and clinical importance. Bilirubin stones also play a crucial role, capturing an increasing share as awareness and diagnosis improve. Concentrated bile and other causes remain less significant but contribute to the diverse landscape of gallstone formation. Growth trends indicate an upward trajectory for bilirubin stones, propelled by rising incidences of hemolytic disorders and improved diagnostic techniques. Cholesterol stones, while dominant, face competition from emerging segments. As healthcare providers focus on personalized treatment strategies and preventive measures, segments like concentrated bile may see increased attention, driving innovation and expanding market offerings.

Cholesterol Stones (Dominant) vs. Bilirubin (Emerging)

Cholesterol stones are characterized by their composition primarily of hardened cholesterol, representing the most common type of gallstones formed in the gallbladder. Their dominance in the market is driven by factors such as obesity, high-fat diets, and lifestyle choices associated with Western diets. On the other hand, bilirubin stones, formed due to excess bilirubin, are increasingly gaining attention as they are linked to specific conditions like liver cirrhosis and certain hemolytic anemias. The growth of this segment is fostered by heightened awareness of related diseases, leading to improved diagnosis and treatment options. As healthcare advances, both segments are likely to innovate, with cholesterol stones focusing on prevention and bilirubin stones enhancing therapeutic approaches.

By Diagnosis: Ultrasound (Largest) vs. Abdominal CT Scan (Fastest-Growing)

In the US gallstone market, the diagnosis segment is primarily dominated by ultrasound, which holds a significant market share. This modality is favored for its non-invasive nature and efficiency in detecting gallstones. Abdominal CT scans follow as a substantial secondary option, providing detailed imaging that aids in accurate diagnosis, although it holds a smaller share compared to ultrasound. Blood tests and Gallbladder Radionuclide Scans represent other options, but their market shares are notably lesser, thus highlighting the strong preference for ultrasound in clinical settings. Growth trends in this segment indicate a rising adoption of advanced imaging technologies, particularly abdominal CT scans, which are witnessing an increased usage due to their higher accuracy and diagnostic capabilities. Additionally, the integration of artificial intelligence in diagnostic imaging is driving innovations and operational efficiencies. As healthcare providers seek to improve diagnostic resolutions and patient outcomes, these trends are expected to bolster the demand for both ultrasound and CT imaging modalities, positioning them favorably in the market.

Ultrasound (Dominant) vs. Abdominal CT Scan (Emerging)

Ultrasound serves as the dominant diagnostic tool in the US gallstone market due to its accessibility, cost-effectiveness, and rapid results. It is widely used in various healthcare settings and often serves as the first-line investigation for patients presenting with symptoms of gallstones. In contrast, the abdominal CT scan is emerging as a vital supplement for cases requiring more detailed visualization, especially in complex scenarios. While ultrasound is preferred for initial diagnostics because of its ease of use, the abdominal CT scan is gaining traction due to advancements in technology that enhance its image quality and diagnostic accuracy, making it a crucial player in patient management strategies.

By Treatment: Laparoscopic Cholecystectomy (Largest) vs. Open Cholecystectomy (Fastest-Growing)

In the US gallstone market, the treatment segment is characterized by diverse methods with varying market shares. Laparoscopic cholecystectomy holds the largest share, favored for its minimally invasive approach and rapid recovery times, appealing to both patients and healthcare providers. Open cholecystectomy, while traditionally significant, is currently the fastest-growing segment due to evolving clinical practices and an increasing number of healthcare institutions offering advanced surgical options. Growth trends within this segment are significantly driven by advancements in surgical techniques and increasing awareness regarding the risks associated with untreated gallstones. The shift towards outpatient surgical procedures has further bolstered the preference for laparoscopic methods. Meanwhile, the medication segment remains stable, focusing on symptom management and prevention, while other treatments are increasingly adopted for their personalized approach, although they comprise a smaller market share.

Laparoscopic Cholecystectomy (Dominant) vs. Open Cholecystectomy (Emerging)

Laparoscopic cholecystectomy is the dominant treatment option in the US gallstone market due to its numerous benefits, such as reduced postoperative pain and shorter hospital stays. This technique has become the standard of care for gallbladder removal, owing to its efficiency and lower complication rates. Conversely, open cholecystectomy, traditionally favored, is seeing a resurgence in certain cases where laparoscopic methods may not be applicable, making it an emerging option. This procedural evolution reflects a combination of surgeon expertise and patient-specific factors that dictate treatment choice, positioning open cholecystectomy as a pivotal player in a developing landscape alongside its laparoscopic counterpart.

Get more detailed insights about US Gallstone Market

Key Players and Competitive Insights

The gallstone market exhibits a competitive landscape characterized by a blend of innovation and strategic partnerships among key players. Major companies such as Boston Scientific (US), Medtronic (US), and Johnson & Johnson (US) are actively shaping the market dynamics through their focus on advanced technologies and patient-centric solutions. Boston Scientific (US) emphasizes innovation in minimally invasive procedures, while Medtronic (US) leverages its extensive portfolio to enhance treatment options. Johnson & Johnson (US) is strategically positioned through its commitment to research and development, aiming to expand its product offerings in the gallstone segment. Collectively, these strategies foster a competitive environment that prioritizes technological advancement and improved patient outcomes.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The market structure appears moderately fragmented, with several players vying for market share. This fragmentation allows for diverse approaches to treatment and innovation, as companies seek to differentiate themselves through unique product offerings and strategic collaborations.

In October 2025, Boston Scientific (US) announced the launch of a new endoscopic ultrasound (EUS) device designed to improve the detection and management of gallstones. This strategic move is likely to enhance the company's competitive edge by providing healthcare professionals with advanced tools for diagnosis and treatment, thereby potentially increasing market penetration. The introduction of such innovative devices aligns with the growing demand for minimally invasive procedures in the gallstone treatment landscape.

In September 2025, Medtronic (US) expanded its partnership with a leading healthcare provider to enhance access to its gallstone management solutions. This collaboration is indicative of Medtronic's strategy to strengthen its market presence through strategic alliances, which may facilitate broader distribution and improved patient access to its advanced technologies. Such partnerships are crucial in navigating the complexities of the healthcare landscape and ensuring that innovative solutions reach the patients who need them most.

In August 2025, Johnson & Johnson (US) unveiled a new digital platform aimed at streamlining the patient experience in gallstone treatment. This initiative reflects the company's commitment to integrating digital solutions into its offerings, potentially enhancing patient engagement and satisfaction. By focusing on digital transformation, Johnson & Johnson is likely positioning itself to meet the evolving needs of healthcare providers and patients alike, thereby reinforcing its competitive stance in the market.

As of November 2025, current trends in the gallstone market indicate a shift towards digitalization, sustainability, and the integration of artificial intelligence (AI) in treatment protocols. Strategic alliances are increasingly shaping the competitive landscape, allowing companies to pool resources and expertise to drive innovation. Looking ahead, competitive differentiation is expected to evolve, with a notable shift from price-based competition to a focus on technological advancements, innovative solutions, and reliable supply chains. This transition underscores the importance of adaptability and forward-thinking strategies in maintaining a competitive edge in the gallstone market.

Key Companies in the US Gallstone Market market include

Industry Developments

The US Gallstone Market has witnessed notable developments recently, particularly related to new therapeutic options and advancements in minimally invasive surgical techniques. Companies like Medtronic and Boston Scientific are innovating in the space, enhancing treatment efficacy and patient outcomes.

In terms of mergers and acquisitions, Hologic announced the acquisition of a minimally invasive technology company in September 2023, aimed at strengthening its portfolio in diagnostic and therapeutic solutions for gallstone disease. There has also been significant growth in the market valuation for Abbott Laboratories and Pfizer, driven by increased demand for advanced diagnostics and treatment solutions over the last two years, due in part to a rise in gallstone incidence among the population, particularly in adults over 40, as documented by the Centers for Disease Control and Prevention (CDC).

Moreover, the FDA has recently streamlined approval processes for gallstone treatment devices, further propelling the market. As per reports from industry associations, the US Gallstone Market is projected to expand notably in the coming years, reflecting ongoing innovations and strategic alliances among leading healthcare companies.

Future Outlook

US Gallstone Market Future Outlook

The Gallstone Market is projected to grow at an 8.04% CAGR from 2024 to 2035, driven by increasing prevalence, advancements in treatment technologies, and rising healthcare expenditure.

New opportunities lie in:

  • Development of minimally invasive surgical techniques for gallstone removal.
  • Expansion of telehealth services for pre- and post-operative care.
  • Investment in AI-driven diagnostic tools for early gallstone detection.

By 2035, the gallstone market is expected to achieve substantial growth, reflecting evolving healthcare dynamics.

Market Segmentation

US Gallstone Market Cause Outlook

  • Cholesterol Stones
  • Bilirubin
  • Concentrated Bile
  • Others

US Gallstone Market Diagnosis Outlook

  • Ultrasound
  • Abdominal CT Scan
  • Gallbladder Radionuclide Scan
  • Blood Tests
  • Others

US Gallstone Market Treatment Outlook

  • Open Cholecystectomy
  • Laparoscopic Cholecystectomy
  • Medications
  • Others

Report Scope

MARKET SIZE 2024 75.6(USD Million)
MARKET SIZE 2025 81.68(USD Million)
MARKET SIZE 2035 177.03(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 8.04% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Boston Scientific (US), Medtronic (US), Johnson & Johnson (US), Baxter International (US), Stryker Corporation (US), Abbott Laboratories (US), Cook Medical (US), Olympus Corporation (JP), Fujifilm Holdings Corporation (JP)
Segments Covered Cause, Diagnosis, Treatment
Key Market Opportunities Advancements in minimally invasive surgical techniques enhance treatment options in the gallstone market.
Key Market Dynamics Rising demand for minimally invasive procedures drives innovation in gallstone treatment technologies within the US market.
Countries Covered US

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FAQs

What is the expected market size of the US Gallstone Market in 2024?

The US Gallstone Market is expected to be valued at 75.6 million USD in 2024.

What is the projected growth rate of the US Gallstone Market from 2025 to 2035?

The US Gallstone Market is expected to grow at a CAGR of 8.582 percent from 2025 to 2035.

What will be the market value of the US Gallstone Market by 2035?

By 2035, the US Gallstone Market is anticipated to reach a value of 187.0 million USD.

Which segment of the US Gallstone Market has the largest share in 2024?

In 2024, the Cholesterol stone segment leads the US Gallstone Market with a valuation of 30.0 million USD.

What are the market values for the Bilirubin segment in 2024 and 2035?

The Bilirubin segment is valued at 20.0 million USD in 2024 and is projected to reach 50.0 million USD by 2035.

Who are the major players in the US Gallstone Market?

Key players in the US Gallstone Market include Hologic, Merck and Co., and C. R. Bard among others.

What is the market value for the Concentrated bile segment in 2035?

The Concentrated bile segment is expected to be valued at 36.0 million USD in 2035.

What challenges could impact the growth of the US Gallstone Market?

The market may face challenges such as regulatory hurdles and rising competition during its growth phase.

What are the expected market trends for the US Gallstone Market from 2025 to 2035?

Emerging trends include technological advancements in treatment options and increasing awareness about gallstone diseases.

What is the market size for the 'Others' segment in 2024?

The 'Others' segment is valued at 10.6 million USD in 2024 within the US Gallstone Market.

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