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Gallstone Market

ID: MRFR/Pharma/1403-HCR
80 Pages
Kinjoll Dey
October 2025

Gallstone Market Research Report Information By Cause (Cholesterol Stone, Bilirubin, Concentrated Bile, and Others), By Diagnosis (Ultrasound, Abdominal CT Scan, Gallbladder Radionuclide Scan, Blood Tests, and Others), By Treatment (Open Cholecystectomy, Laparoscopic Cholecystectomy, Medications, and Others), and By Region (North America, Europe, Asia-Pacific, and Rest Of The World) – Market Forecast Till 2035

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Gallstone Market Summary

As per MRFR analysis, the Gallstone Market Size was estimated at 0.36 USD Billion in 2024. The Gallstone industry is projected to grow from 0.389 in 2025 to 0.843 by 2035, exhibiting a compound annual growth rate (CAGR) of 8.04 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The gallstone market is experiencing notable growth driven by technological advancements and increasing awareness.

  • North America remains the largest market for gallstones, driven by high healthcare expenditure and advanced medical facilities.
  • The Asia-Pacific region is emerging as the fastest-growing market, fueled by demographic shifts and rising healthcare access.
  • Cholesterol stones represent the largest segment, while bilirubin stones are witnessing the fastest growth due to changing dietary habits.
  • Key market drivers include the increasing prevalence of gallstones and advancements in minimally invasive procedures, enhancing treatment options.

Market Size & Forecast

2024 Market Size 0.36 (USD Billion)
2035 Market Size 0.843 (USD Billion)
CAGR (2025 - 2035) 8.04%

Major Players

AbbVie Inc (US), Bristol-Myers Squibb Company (US), Merck & Co., Inc. (US), Amgen Inc (US), Novartis AG (CH), Pfizer Inc (US), Gilead Sciences, Inc. (US), AstraZeneca PLC (GB), Johnson & Johnson (US)

Gallstone Market Trends

The Gallstone Market is currently experiencing notable transformations driven by various factors. Increasing awareness regarding gallstone-related health issues appears to be influencing consumer behavior, leading to a heightened demand for effective treatment options. Additionally, advancements in medical technology and surgical procedures are likely enhancing the efficacy of gallstone management, thereby attracting more patients seeking relief from this condition. Furthermore, the growing prevalence of obesity and related metabolic disorders may contribute to a rise in gallstone cases, prompting healthcare providers to focus on preventive measures and innovative therapies. Moreover, the market landscape is evolving with the introduction of minimally invasive techniques, which seem to offer patients quicker recovery times and reduced hospital stays. This shift towards less invasive options may be appealing to both patients and healthcare professionals, potentially reshaping treatment paradigms. As the Gallstone Market continues to develop, stakeholders must remain vigilant to emerging trends and adapt strategies accordingly to meet the changing needs of patients and healthcare systems.

Rising Awareness and Education

There is an increasing emphasis on educating the public about gallstone risks and symptoms. This trend appears to be fostering proactive health management, encouraging individuals to seek medical advice sooner.

Technological Advancements in Treatment

Innovations in medical technology, particularly in surgical techniques, are likely improving treatment outcomes. These advancements may lead to more effective and less invasive options for gallstone removal.

Focus on Preventive Healthcare

With the growing incidence of obesity, there seems to be a stronger focus on preventive measures. Healthcare providers are increasingly promoting lifestyle changes to mitigate gallstone formation.

Gallstone Market Drivers

Rising Healthcare Expenditure

The upward trend in healthcare spending is influencing the Gallstone Market significantly. As countries invest more in healthcare infrastructure and services, access to diagnostic and treatment options for gallstones improves. Increased healthcare expenditure allows for better patient education, awareness campaigns, and the availability of advanced medical technologies. According to recent statistics, healthcare spending is projected to grow at a compound annual growth rate of around 5% over the next few years. This financial commitment from both public and private sectors is likely to enhance the overall management of gallstone diseases, thereby driving demand within the Gallstone Market.

Increasing Prevalence of Gallstones

The rising incidence of gallstones is a primary driver of the Gallstone Market. Studies indicate that approximately 10 to 15% of adults may develop gallstones at some point in their lives. Factors such as obesity, diabetes, and dietary habits contribute to this trend. As the population ages, the prevalence of gallstones is expected to increase, leading to a higher demand for treatment options. This growing patient population necessitates advancements in both surgical and non-surgical interventions, thereby propelling the Gallstone Market forward. Furthermore, the economic burden associated with gallstone-related complications, such as cholecystitis, underscores the need for effective management strategies, which could further stimulate market growth.

Growing Focus on Preventive Healthcare

The shift towards preventive healthcare is emerging as a crucial driver in the Gallstone Market. With an increasing emphasis on lifestyle modifications, such as diet and exercise, healthcare providers are advocating for preventive measures to reduce the risk of gallstone formation. Public health initiatives aimed at educating individuals about the importance of maintaining a healthy weight and balanced diet are gaining traction. This proactive approach not only aims to decrease the incidence of gallstones but also reduces the long-term healthcare costs associated with treatment. As awareness grows, the demand for preventive solutions and educational resources within the Gallstone Market is likely to expand.

Emerging Markets and Demographic Shifts

Demographic changes and the emergence of new markets are shaping the Gallstone Market. As urbanization increases, lifestyle changes often lead to higher rates of obesity and gallstone formation. Countries experiencing rapid economic growth are witnessing a rise in disposable incomes, which may lead to increased healthcare access and consumption of gallstone treatments. Additionally, the aging population in many regions is expected to contribute to a higher prevalence of gallstones. This demographic shift presents both challenges and opportunities for the Gallstone Market, as stakeholders must adapt to the evolving needs of diverse populations while addressing the growing demand for effective treatment options.

Advancements in Minimally Invasive Procedures

Technological innovations in minimally invasive surgical techniques are transforming the Gallstone Market. Procedures such as laparoscopic cholecystectomy have gained popularity due to their reduced recovery times and lower complication rates compared to traditional open surgery. The introduction of robotic-assisted surgeries is also enhancing precision and outcomes, appealing to both patients and healthcare providers. As these technologies become more widely adopted, they are likely to increase the overall treatment capacity for gallstone-related conditions. Market data suggests that the minimally invasive segment is expected to witness substantial growth, driven by patient preference for less invasive options and the increasing availability of advanced surgical tools.

Market Segment Insights

Gallstone Market Cause Insights

The Gallstone Market segmentation, based on cause, includes cholesterol stones, bilirubin, concentrated bile, and others. Cholesterol stones segment dominated the market in 2022. Gallstones cause gallbladder inflammation, which is the condition known as cholesterol stones. The high prevalence and incidence of cholecystitis are the cause of the segment dominance. For instance, the incidence rate of acute cholecystitis is around 6,300 per 100,000 people worldwide under the age of 50 and 20,900 per 100,000 people over the age of 50.

Gallstone Market Diagnosis Insights

The Gallstone Market segmentation, based on diagnosis, includes ultrasound, abdominal CT scan, gallbladder radionuclide scan, blood tests, and others. Ultrasound segment dominated the market in 2022. This is due to elements including the growing prevalence of gallstone disease and the increased knowledge of early illness diagnosis.

Gallstone Market Treatment Insights

The Gallstone Market segmentation, based on treatment, includes open cholecystectomy, laparoscopic cholecystectomy, medications, and others. Laparoscopic cholecystectomy segment dominated the Gallstone Market in 2022.The laparoscopic cholecystectomy typically takes one to two hours to complete and involves inserting a small video camera through a small incision in the abdomen. The benefits of laparoscopic surgery, such as a shorter hospital stay, less blood loss, and fewer patient morbidity, have recently helped it become more popular. A tiny or no incision, a speedy recovery, quick and successful results, a minimal risk of infection, and less pain are further benefits.

Since laparoscopic cholecystectomy surgery is in high demand, the market for cholecystectomy equipment is anticipated to grow throughout the forecast period. In addition, open cholecystectomy is a traditional procedure reserved for situations where laparoscopic cholecystectomy operations cannot be performed safely. A slower growth rate and a smaller market share for the segment have been the results of important variables, including recent technological developments, an increased desire for less invasive surgeries, longer postoperative hospital stays, severe bleeding, and common bile duct injuries.

Figure 1: Gallstone Market, by Treatment, 2022 & 2032 (USD Billion)

Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

Get more detailed insights about Gallstone Market

Regional Insights

North America : Leading Market for Innovation

North America is the largest market for gallstones, accounting for approximately 45% of the global market share. The region's growth is driven by increasing obesity rates, a higher prevalence of gallstone-related diseases, and advancements in medical technology. Regulatory support from agencies like the FDA facilitates the introduction of innovative treatments, further boosting market demand. The U.S. is the primary contributor, followed by Canada, which holds around 15% of the market share. The competitive landscape in North America is characterized by the presence of major pharmaceutical companies such as AbbVie Inc, Merck & Co., and Pfizer Inc. These companies are actively involved in research and development to introduce new therapies for gallstone management. The market is also witnessing collaborations and partnerships aimed at enhancing treatment options, ensuring that patients have access to the latest advancements in gallstone care.

Europe : Emerging Market with Growth Potential

Europe is witnessing a growing demand for gallstone treatments, holding approximately 30% of the global market share. The increase in gallstone prevalence is attributed to lifestyle changes, dietary habits, and an aging population. Countries like Germany and France are leading the market, driven by robust healthcare systems and increasing awareness about gallstone-related health issues. Regulatory frameworks in the EU support the development of new therapies, enhancing market growth. Germany is the largest market in Europe, followed by France, which contributes significantly to the overall market dynamics. The competitive landscape includes key players such as Novartis AG and AstraZeneca PLC, who are focusing on innovative treatment solutions. The presence of advanced healthcare infrastructure and a strong emphasis on research and development further bolster the market, making Europe a vital region for gallstone management advancements.

Asia-Pacific : Rapidly Growing Healthcare Sector

The Asia-Pacific region is emerging as a significant player in the gallstone market, accounting for approximately 20% of the global share. The growth is driven by increasing urbanization, rising disposable incomes, and a growing awareness of health issues related to gallstones. Countries like China and India are at the forefront, with China holding the largest market share in the region, supported by a vast population and increasing healthcare investments. The competitive landscape in Asia-Pacific is evolving, with both local and international players vying for market share. Companies such as Gilead Sciences and Amgen are expanding their presence in the region, focusing on innovative treatment options. The region's healthcare sector is rapidly developing, with improvements in medical facilities and access to advanced treatments, contributing to the overall growth of the gallstone market.

Middle East and Africa : Emerging Market with Unique Challenges

The Middle East and Africa region is gradually developing in the gallstone market, holding about 5% of the global share. The growth is primarily driven by increasing healthcare access, rising awareness of gallstone diseases, and lifestyle changes leading to higher obesity rates. Countries like South Africa and the UAE are leading the market, with South Africa being the largest contributor due to its improving healthcare infrastructure and investment in medical technologies. The competitive landscape in this region is characterized by a mix of local and international players. Companies are focusing on expanding their product offerings and improving access to treatments. However, challenges such as economic disparities and varying healthcare standards across countries can impact market growth. The region's potential for growth remains significant as healthcare systems continue to evolve and improve.

Gallstone Market Regional Image

Key Players and Competitive Insights

Leading market players are investing heavily in research and development in order to expand their product lines, which will help the Gallstone Market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, Gallstone Industry must offer cost-effective items.

Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the Gallstone Industry to benefit clients and increase the market sector. In recent years, the Gallstone Industry has offered some of the most significant advantages to medicine. Major players in the Gallstone Market, including Sklar Surgical Instruments, Fortimedix Surgical, Intuitive Surgical Inc., Levita Magnetics, Olympus, Medtronic plc, NovaTract Surgical, LLC, and Simulab Corporation, are attempting to increase market demand by investing in research and development operations.

A magnetic surgical device created by Levita Magnetics uses traumatic, shaftless, and magnetic retraction to enable single- and reduced-port surgeries. The company's method enables patients to minimise surgical trauma while maximising cosmetic outcomes by doing away with the necessity for a dedicated trocar and shafted instruments that may clog the operating field during a reduced port laparoscopic cholecystectomy surgery. Using the FDA-approved LevitaTM Magnetic Surgical System, Levita Magnetics announced the completion of the first magnetic scarless robotic gallbladder surgery in December 2016.

Less invasive surgery is made possible by a magnetic-robotic process, which promises better patient outcomes with reduced pain, scarring, and recovery times.

 A medical technology firm called Medtronic Plc (Medtronic), originally known as Medtronic Inc., creates, develops, produces, and sells a variety of medical products. It provides products for the treatment of conditions such heart valve issues, heart failure, aortic, peripheral vascular, venous renal, and neurological problems, as well as spine and musculoskeletal issues, ear, nose, and throat conditions.

Key Companies in the Gallstone Market market include

Industry Developments

April 2022:Around 20 million Americans are thought to have gallstone disease, according to an NCBI article. Among them, cholecystectomy procedures are carried out annually in close to 300,000 cases. Around 20% of gallstones are symptomatic, while only about 10% are asymptomatic.

Future Outlook

Gallstone Market Future Outlook

The Gallstone Market is projected to grow at an 8.04% CAGR from 2024 to 2035, driven by increasing prevalence, advancements in treatment technologies, and rising healthcare expenditures.

New opportunities lie in:

  • Development of minimally invasive surgical techniques for gallstone removal.
  • Expansion of telehealth services for patient consultations and follow-ups.
  • Investment in AI-driven diagnostic tools for early gallstone detection.

By 2035, the Gallstone Market is expected to achieve substantial growth, reflecting evolving healthcare dynamics.

Market Segmentation

Gallstone Market Cause Outlook

  • Cholesterol Stones
  • Bilirubin
  • Concentrated Bile
  • Others

Gallstone Market Diagnosis Outlook

  • Ultrasound
  • Abdominal CT Scan
  • Gallbladder Radionuclide Scan
  • Blood Tests
  • Others

Gallstone Market Treatment Outlook

  • Open Cholecystectomy
  • Laparoscopic Cholecystectomy
  • Medications
  • Others

Report Scope

MARKET SIZE 20240.36(USD Billion)
MARKET SIZE 20250.389(USD Billion)
MARKET SIZE 20350.843(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)8.04% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMarket analysis in progress
Segments CoveredMarket segmentation analysis in progress
Key Market OpportunitiesAdvancements in minimally invasive surgical techniques enhance treatment options in the Gallstone Market.
Key Market DynamicsRising prevalence of gallstones drives demand for innovative treatment options and minimally invasive surgical techniques.
Countries CoveredNorth America, Europe, APAC, South America, MEA

Market Highlights

Author
Kinjoll Dey
Research Analyst Level I

He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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FAQs

What is the current valuation of the Gallstone Market as of 2024?

The Gallstone Market was valued at 0.36 USD Billion in 2024.

What is the projected market valuation for the Gallstone Market in 2035?

The Gallstone Market is projected to reach a valuation of 0.843 USD Billion by 2035.

What is the expected CAGR for the Gallstone Market during the forecast period 2025 - 2035?

The expected CAGR for the Gallstone Market during the forecast period 2025 - 2035 is 8.04%.

Which companies are considered key players in the Gallstone Market?

Key players in the Gallstone Market include AbbVie Inc, Bristol-Myers Squibb Company, Merck & Co., Inc., and others.

What are the main causes of gallstones in the market segments?

The main causes of gallstones include Cholesterol Stones, Bilirubin, and Concentrated Bile, with Cholesterol Stones valued at 0.144 USD Billion in 2024.

How is the Gallstone Market segmented by diagnosis methods?

The Gallstone Market is segmented by diagnosis methods, with Ultrasound valued at 0.12 USD Billion in 2024.

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