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South America RNA-Based Therapeutics Market Research Report By Technology (RNA Interference, Antisense Oligonucleotides, mRNA Therapeutics, CRISPR Technology), By Application (Oncology, Infectious Diseases, Genetic Disorders, Cardiovascular Diseases), By End Use (Pharmaceutical Companies, Research Institutions, Contract Research Organizations), By Delivery Method (Liposomes, Nanoparticles, Viral Vectors, Electroporation) and By Regional (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035


ID: MRFR/HC/50895-HCR | 200 Pages | Author: Garvit Vyas| July 2025

South America RNA-Based Therapeutics Market Overview


As per MRFR analysis, the South America RNA-Based Therapeutics Market Size was estimated at 770 (USD Million) in 2023. The South America RNA-Based Therapeutics Market Industry is expected to grow from 849 (USD Million) in 2024 to 2,500 (USD Million) by 2035. The South America RNA-Based Therapeutics Market CAGR (growth rate) is expected to be around 10.316% during the forecast period (2025 - 2035).


Key South America RNA-Based Therapeutics Market Trends Highlighted


The South America RNA-Based Therapeutics Market is witnessing notable trends driven by several factors. One significant market driver is the increasing prevalence of genetic disorders and chronic diseases in the region, which has heightened the demand for innovative treatment solutions. Many South American countries are enhancing their healthcare infrastructures and investing in biotechnology research, fostering an environment conducive to the growth of RNA-based therapies.


Government initiatives aimed at supporting biotech companies through funding and regulatory reforms are also key contributors to the expansion of this market. Opportunities in the South American RNA-Based Therapeutics Market include collaborations between local research institutions and international pharmaceutical companies. Such partnerships can facilitate knowledge transfer and accelerate the development of new RNA-based therapies tailored to the unique genetic profiles found in South American populations.


Furthermore, there is significant potential for the application of RNA technology in vaccine development, especially given the recent global focus on infectious diseases and pandemics, with many countries in the region adapting their public health strategies accordingly. Recent trends also reflect a growing interest in personalized medicine, which is becoming increasingly important in South America. Advancements in genomics and biotechnology are paving the way for targeted therapies that address the specific needs of individual patients.


Moreover, as governments prioritize healthcare investments, there is an emerging emphasis on regulatory flexibility to expedite the approval of innovative therapies, which is crucial for meeting the health challenges faced by the region. This combination of supportive government policies, collaborations, and a focus on personalized medicine is shaping a dynamic landscape for RNA-based therapeutics in South America.


South America RNA-based Therapeutics Market size


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


South America RNA-Based Therapeutics Market Drivers


Rising Incidence of Genetic Disorders


In South America, the incidence of genetic disorders is increasing, leading to a higher demand for RNA-based therapeutics which can target these conditions effectively. According to the Pan American Health Organization, genetic disorders affect over 1 in 1,000 live births in the region, indicating a significant patient base needing advanced therapies. Organizations like the Brazilian Society of Medical Genetics are actively working to raise awareness and promote Research and Development (R&D) in this sector.


This increased incidence of genetic disorders creates substantial growth opportunities for the South America RNA-Based Therapeutics Market Industry as more patients seek innovative treatment options.


Government Support and Funding


Governments across South America are increasingly investing in bio-pharmaceuticals and RNA-based therapeutics as part of their health care initiatives. The National Health Ministry of Argentina announced a significant increase in funding for biotechnology projects, promoting innovation in therapeutics. This governmental backing fosters an environment conducive for Research and Development (R&D) and encourages private investments, boosting the South America RNA-Based Therapeutics Market Industry.


With an estimated 20% increase in government allocations for health research, the support translates into more resources and programs aimed at enhancing therapeutic effectiveness and accessibility in the region.


Growing Collaborations in Research


The advancement of RNA-based therapies is being expedited by partnerships between pharmaceutical companies and academic institutions in South America. The University of São Paulo has formed partnerships with private companies to improve its research and development (R&D) initiatives that concentrate on mRNA technologies. According to a report from the Brazilian Association of Pharmaceutical Research, the number of such collaborations has increased by more than 30% in the past three years, indicating a strong interest in innovation in the RNA therapeutic market.


These partnerships are essential for the advancement of the South American RNA-Based Therapeutics Market Industry, which in turn provides improved treatment options for a variety of diseases.


South America RNA-Based Therapeutics Market Segment Insights


RNA-Based Therapeutics Market Technology Insights


The South America RNA-Based Therapeutics Market has shown substantial growth, particularly within the Technology segment, which encompasses innovative areas such as RNA Interference, Antisense Oligonucleotides, mRNA Therapeutics, and CRISPR Technology. RNA Interference is vital for its ability to silence specific genes involved in various diseases, thus offering targeted therapies with reduced side effects, which is particularly significant in managing complex conditions like cancer and genetic disorders.


Conversely, Antisense Oligonucleotides provide robust tools for modulating gene expression, with a focus on treating rare and chronic diseases, showcasing the segment's capacity to address unmet medical needs across the region. mRNA Therapeutics has gained traction with the rising acceptance of mRNA technology exemplified during the recent health crisis, proving this approach can be pivotal for rapid vaccine development and therapeutic solutions, which aligns well with the regional emphasis on improving healthcare infrastructure.


Additionally, CRISPR Technology marks a revolutionary advancement in genetic engineering, allowing for precise modifications to the genome, which opens prospects for innovative treatments in South America by tackling genetic mutations and potential hereditary diseases. The growing demand for personalized medicine and biotechnology innovations is propelling these technological segments forward, highlighting the region's strategic focus on enhancing its healthcare capabilities.


As South America looks to invest in biotechnology, these technologies not only represent significant market opportunities but also promise enhanced healthcare solutions that cater to the unique needs of the population.


South America RNA-based Therapeutics Market Segment


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


RNA-Based Therapeutics Market Application Insights


The Application segment of the South America RNA-Based Therapeutics Market showcases significant opportunities and growth potential, driven by increasing rates of oncological and infectious diseases in the region. Oncology, in particular, plays a critical role within this segment due to the rising prevalence of cancer, prompting a surge in innovative RNA-based therapies aimed at improving treatment outcomes. Infectious diseases also present a pressing healthcare challenge in South America, where RNA therapeutics offer novel solutions for tackling urgent public health concerns, including viral outbreaks and bacterial infections.


Genetic disorders are gaining attention, with RNA therapeutics offering hope for effective treatments through gene silencing and editing technologies. Meanwhile, the cardiovascular diseases sector remains pivotal, as research focuses on RNA modalities that can improve heart health and reduce systemic risks. Collectively, these applications are poised to address significant health issues in the region, offering therapeutic advancements that align with the urgent healthcare needs and market dynamics of South America.


As these therapeutic modalities evolve, they have the potential to reshape the healthcare landscape while contributing to the overall growth of the South America RNA-Based Therapeutics Market.


RNA-Based Therapeutics Market End Use Insights


The South America RNA-Based Therapeutics Market is witnessing significant growth driven by its end use across various domains, notably Pharmaceutical Companies, Research Institutions, and Contract Research Organizations. Pharmaceutical Companies play a critical role as they leverage RNA-based therapies to innovate and develop novel medicines, reflecting a growing trend in precision medicine and targeted treatments. Research Institutions are also pivotal, focusing on cutting-edge studies that explore the potential of RNA therapies in treating various diseases, thereby fueling advancements in the market.


Moreover, Contract Research Organizations have emerged as key players, providing essential support to pharmaceutical companies and institutions in the form of specialized services, clinical trials, and R&D expertise. The interplay among these players results in a dynamic ecosystem that fosters rapid advancements and enhances the overall landscape of RNA-based therapeutics in South America. This synergy not only aids in efficient product development but also opens avenues for collaboration and funding, enhancing the market's resilience and adaptability in response to evolving healthcare needs.


Overall, the diverse end use applications underline the importance of RNA-based therapeutics in revolutionizing treatment paradigms and responding to the unmet medical needs in the region.


RNA-Based Therapeutics Market Delivery Method Insights


The Delivery Method segment of the South America RNA-Based Therapeutics Market is increasingly gaining attention due to its pivotal role in the effective administration of RNA-based therapeutics. Various techniques are explored within this segment, such as Liposomes, which are recognized for their ability to encapsulate and deliver RNA molecules efficiently, enhancing the stability and bioavailability of therapeutics. Nanoparticles are another critical technology, favored for their versatility and capability to target specific cells, thereby minimizing off-target effects.


Viral Vectors dominate the landscape as they are naturally adept at delivering genetic material into cells, making them significant for therapeutic applications. Electroporation also plays a pivotal role, allowing for the efficient introduction of RNA into cells through electrical pulses, promoting the uptake of therapeutics. The growing focus on precision medicine and personalized therapies is propelling innovation within these delivery methods, addressing the unique health needs of diverse populations in South America. Overall, the advancements in this segment are expected to drive substantial growth and enhance treatment outcomes across various indications in the region.


RNA-Based Therapeutics Market Regional Insights


The South America RNA-Based Therapeutics Market is experiencing notable growth across its regional segmentation, prominently featuring Brazil, Mexico, Argentina, and the Rest of South America. Brazil stands out as a leading market, driven by its robust healthcare infrastructure, increasing investments in Research and Development, and a growing focus on innovative therapeutics. Mexico is also emerging, characterized by a burgeoning biotech sector and supportive government policies aimed at enhancing health outcomes through advanced treatments.


Argentina demonstrates significant potential due to its skilled workforce and emphasis on local bio-pharmaceutical production, which fosters a strong research environment. Meanwhile, the Rest of South America contributes substantially through diverse regional initiatives that encourage the adoption of RNA-based therapies. Overall, this regional expansion is fueled by increasing healthcare demands, technological advancements, and a growing recognition of RNA-based therapeutics' potential to treat various diseases, enriching the South America RNA-Based Therapeutics Market data and statistics.


As stakeholders continue to invest in this sector, opportunities for innovation and collaboration abound, paving the way for future market growth.


South America RNA-based Therapeutics Market Region


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


South America RNA-Based Therapeutics Market Key Players and Competitive Insights


The South America RNA-Based Therapeutics Market has gained significant traction over the past few years, attracting notable interest from both established and emerging players. This burgeoning market is characterized by rapid advancements in biotechnology, the growing prevalence of chronic diseases, and a shifting landscape towards personalized medicine. Companies are focusing on developing innovative RNA-based solutions, generating fierce competition that drives investments in research and development.


The rise in collaborations between academic institutions and pharmaceutical companies is also fostering a robust ecosystem conducive to the growth of RNA therapeutics. As a result, stakeholders are keenly assessing market trends, regulatory frameworks, and competitive strategies to enhance their positions and capitalize on the forecasted growth opportunities in the region.


In the South America RNA-Based Therapeutics Market, CureVac commands a notable presence with its innovative mRNA technology platform. The company is well-regarded for its commitment to developing transformative therapies that address unmet medical needs. CureVac leverages its strengths in clinical research and development, showcasing a robust pipeline of products targeting a variety of diseases, including cancer and infectious diseases. The firm has been proactive in establishing strategic partnerships and collaborations with local research entities, which have not only bolstered its market position but also enhanced its capabilities in navigating regulatory environments across South America.


This agile approach, combined with a focus on delivering high-quality RNA therapeutics, underlines CureVac's potential for continued growth in the region. BioNTech has also gained significant recognition in the South America RNA-Based Therapeutics Market, primarily due to its pioneering work in mRNA-based vaccines and therapies. The company has positioned itself as a leader by launching key products aimed at various therapeutic areas, which has resonated well in the region. BioNTech's strengths lie in its innovative research framework, extensive intellectual property, and partnerships with local organizations that facilitate development and distribution.


Recent mergers and acquisitions have further expanded its reach and capabilities, enhancing its service offerings like customized cancer immunotherapies tailored for specific patient needs. By investing in local manufacturing capabilities and engaging in collaborative initiatives, BioNTech is well-placed to strengthen its competitive edge and deliver impactful RNA-based solutions to the South American market.


Key Companies in the South America RNA-Based Therapeutics Market Include



    • CureVac

    • BioNTech

    • Alnylam Pharmaceuticals

    • Regeneron Pharmaceuticals

    • Ionis Pharmaceuticals

    • Moderna

    • Sangamo Therapeutics

    • Novartis

    • Pfizer

    • Intellia Therapeutics

    • Translate Bio

    • Arcturus Therapeutics

    • Dicerna Pharmaceuticals

    • Silence Therapeutics


South America RNA-Based Therapeutics Market Industry Developments


The South America RNA-Based Therapeutics Market has recently seen significant developments, particularly with key companies like Moderna, BioNTech, and CureVac leading advancements in mRNA technology applications. In August 2023, Moderna announced collaboration with local Brazilian firms to enhance its mRNA vaccine distribution capabilities, aiming to address health challenges in the region. Alnylam Pharmaceuticals continues to expand its presence with state-of-the-art facilities in Brazil, focusing on developing RNA interference therapies.


Notably, in June 2023, Pfizer and BioNTech solidified their partnership, targeting RNA-based treatments for malaria, with clinical trials expected to start soon. The market has witnessed a rise in valuations due to increasing investments, particularly driven by growing demand for rapid vaccine development and personalized medicine. Major happenings include Regeneron Pharmaceuticals unveiling its RNA therapeutics pipeline in November 2022, which focuses on chronic diseases prevalent in South America.


The overall growth in this sector reflects the increasing governmental support for biotechnology initiatives and collaborations across borders to facilitate Research and Development efforts in RNA technology. These trends indicate a proactive approach towards enhancing healthcare outcomes in South America through innovative RNA therapeutic solutions.


South America RNA-Based Therapeutics Market Segmentation Insights


RNA-Based Therapeutics Market Technology Outlook



    • RNA Interference

    • Antisense Oligonucleotides

    • mRNA Therapeutics

    • CRISPR Technology


RNA-Based Therapeutics Market Application Outlook



    • Oncology

    • Infectious Diseases

    • Genetic Disorders

    • Cardiovascular Diseases


RNA-Based Therapeutics Market End Use Outlook



    • Pharmaceutical Companies

    • Research Institutions

    • Contract Research Organizations


RNA-Based Therapeutics Market Delivery Method Outlook



    • Liposomes

    • Nanoparticles

    • Viral Vectors

    • Electroporation


RNA-Based Therapeutics Market Regional Outlook



    • Brazil

    • Mexico

    • Argentina

    • Rest of South America

Report Attribute/Metric Details
Market Size 2023 770.0(USD Million)
Market Size 2024 849.0(USD Million)
Market Size 2035 2500.0(USD Million)
Compound Annual Growth Rate (CAGR) 10.316% (2025 - 2035)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled CureVac, BioNTech, Alnylam Pharmaceuticals, Regeneron Pharmaceuticals, Ionis Pharmaceuticals, Moderna, Sangamo Therapeutics, Novartis, Pfizer, Intellia Therapeutics, Translate Bio, Arcturus Therapeutics, Dicerna Pharmaceuticals, Silence Therapeutics
Segments Covered Technology, Application, End Use, Delivery Method, Regional
Key Market Opportunities Growing infectious disease prevalence, Expanding biotech investments, Increasing personalized medicine demand, Advancements in gene editing technologies, Expanding regulatory support for innovations
Key Market Dynamics Rising prevalence of genetic disorders, Increasing investment in R&D, Growing demand for personalized medicine, Advancements in RNA technology, Collaborative partnerships in biopharma
Countries Covered Brazil, Mexico, Argentina, Rest of South America


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