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    Overt Hepatic Encephalopathy Companies

    ID: MRFR/Pharma/0280-HCR
    95 Pages
    Kinjoll Dey
    October 2025

    Overt hepatic encephalopathy refers to the advanced stage of hepatic encephalopathy, a condition associated with liver dysfunction. Companies involved in overt hepatic encephalopathy may focus on developing pharmaceuticals or medical interventions to manage and treat this serious neurological complication of liver disease.

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    Top Industry Leaders in the Overt Hepatic Encephalopathy Market

    Overt Hepatic Encephalopathy Market


    Latest North America Microarray Companies Updates


    VEDANTA BIOSCIENCES: Phase 3 trial (PEARL) evaluating VE303, a novel gut-selective antibiotic, met its primary endpoint of reducing the frequency of OHE episodes in patients with cirrhosis compared to placebo. This is a significant step towards potentially offering a new treatment option for OHE.


    AXCELLA HEALTH: Positive top-line data from Phase 2b trial of AXA1665, a gut-selective antibiotic, showed a trend towards reducing OHE events and improving cognitive function in patients with cirrhosis. Phase 3 trials are planned.


    SALIX PHARMACEUTICALS: Ongoing observational study evaluating the real-world effectiveness of rifaximin in preventing OHE recurrence in patients with cirrhosis. Results are expected to provide valuable insights into long-term treatment strategies.


    List of North America Microarray Key companies in the market:



    • Alfa Wassermann S.P.A

    • Cosmo Pharmaceuticals S.P.A

    • Horizon Pharma Plc.

    • KannaLife Sciences, Inc.

    • Ocer Therapeutics

    • Rebiotix Inc.

    • Spherium Biomed S.L

    • Umecrine Cognition AB

    • ASKA Pharmaceutical

    • Mallinckrodt

    • Valeant