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Heart Failure Drugs Market Trends

ID: MRFR//7288-CR | 104 Pages | Author: Rahul Gotadki| February 2020

Global Heart Failure Drugs Market Overview

Heart Failure Drugs Market Size was valued at USD 11.6 billion in 2021 and is projected to grow from USD 12.28 Billion in 2022 to USD 20.57 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 5.9% during the forecast period (2023 - 2032). Rising cardiovascular disorders and developments of several heart failure drugs are the key market drivers enhancing the market growth.Heart Failure Drugs Market Overview

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

Heart Failure Drugs Market Trends

  • Robust pipeline of drugs under development to boost market growth

A major driver of the growth of the heart failure drugs market is the strong drug pipeline under development. For instance, furosemide injection (SCP-101), sponsored by Johns Hopkins University in collaboration with his Scpharmaceuticals Inc., went into Phase 2 clinical trials in 2015. This injection is indicated for the treatment of heart failure. Furosemide and azosemide, sponsored by Hyogo College of Medicine, completed Phase 4 clinical trials in 2016. These drugs are used to treat heart failure. Sponsored by Otsuka Pharmaceutical Co., Ltd., tolvaptan was in Phase 3 clinical trials in 2016, and the drug is indicated for the treatment of heart failure in children.

Further, approval of new drugs by the Food and Drug Administration (FDA) is also expected to fuel the growth of the congestive heart failure drugs market. In 2016, the FDA approved his Byvalson from Ireland-based company, Allergan. This drug is used to treat high blood pressure. In 2015, the FDA approved Corlanor (ivabradine) from US-based company Amgen Inc. This drug treats chronic heart failure. In addition, rising geriatric population, unhealthy lifestyle, and growing awareness of chronic disease management are boosting the heart failure drugs market CAGR.

Due to the increasing work pressure and stress of the younger generation, the problem of heart failure disease is also increasing. People belonging to the elderly group already have many cardiovascular diseases, which will help boost the heart failure drugs market significantly. Even small changes in cardiovascular rhythms and velocities contribute to the significant growth of the cardiovascular drug market. Not only the elderly, but also the younger generation have many lifestyle-related cardiovascular diseases. Therefore, the heart failure Drugs Market has increased significantly with the prevalence of cardiac arrest among the people. However, the change in lifestyle such as excessive alcohol consumption, smoking and unhealthy diet habits causes heart problems is another factor driving the growth of the Heart Failure Drugs market revenue.

Heart Failure Drugs Market Segment Insights

Heart Failure Drugs Type Insights

The Heart Failure Drugs market segmentation, based on type, includes Beta-Blockers, ACE Inhibitors, Angiotensin-Receptor Neprilysin Inhibitors, Angiotensin Receptor Blockers, and Diuretic. The ACE inhibitors Heart Failure Drugs segment held the majority share in 2021 contribution to around in respect to the Heart Failure Drugs market revenue. ACE inhibitors prevent the formation of angiotensin, which causes blood vessels to constrict, and beta blockers block the actions of certain chemicals. ACE inhibitors are mainly used in the treatment of heart failure. These agents decrease the formation of angiotensin II, thereby decreasing both arteriolar and venous resistance.

Heart Failure Drugs End Users Insights

Based on End Users, the Heart Failure Drugs industry has been segmented into Hospitals, and specialty centers. Hospitals have seen the highest growth due to rapid demand and supply of cardiovascular drugs due to the ready availability of rare and commonly used drugs. Cardiovascular emergency medicines are readily available in hospital pharmacies, but pharmacies are very expensive and only available in hospitals.

Specialty centers is the next fastest growing segment due to that it provides specialty services focusing on specific business needs, including assistance relating. The ability to directly compare other available medicines also helps consumers to choose the right medicine.

August 2021 the Eli Lilly and Company announced that the US FDA had approved Jardiance (empagliflozin) 10 mg to reduce the risk of cardiovascular death plus hospitalization for heart failure in adults with HFrEF.

Figure 2  Heart Failure Drugs Market, by End Users, 2022 & 2032 (USD Billion)

Heart Failure Drugs Market, by End Users, 2022 & 2032 (USD Billion)

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

Heart Failure Drugs Regional Insights

By Region, the study provides the market insights for Heart Failure Drugs into North America, Europe, Asia-Pacific and Rest of the World. North America Heart Failure Drugs market accounted for USD 5.01 billion in 2021 and is expected to exhibit a significant CAGR growth of 43.20% during the study period. This is attributed to the rise in the rate of cardiovascular disorders, increasing obesity cases among people and growing healthcare expenditure across the region.

Further, the major countries studied in the market report for Heart Failure Drugs are The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure 3 Heart Failure Drugs Market Share By Region 2022 (%)

Heart Failure Drugs Market Share By Region 2022 (%)

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

Europe Heart Failure Drugs market accounts for one of the largest market share due to the availability of cutting-edge treatment facilities, government backing for the growth of the healthcare industry, and an increase in incidence of heart failure. Further, the Germany Heart Failure Drugs market held the largest market share, and the UK Heart Failure Drugs market was the fastest growing market in the European region.

The Asia-Pacific Heart Failure Drugs Market is expected to grow at the fastest CAGR from 2023 to 2030. This is due to growing patient pool, initiatives by the government to enhance quality of healthcare, rise in cardiovascular disorder cases and increase in disposable income. For instance, Australia's anticipated prevalence rate of CHF in 2020 ranged from 1.2% to 5.3%, primarily as a result of the nation's rising rates of diabetes and obesity. Moreover, China Heart Failure Drugs market held the largest market share, and the India Heart Failure Drugs market was the fastest growing market in the Asia-Pacific region.

Heart Failure Drugs Key Market Players & Competitive Insights

Major market players are spending a lot of money on R&D to increase their product lines, which will help the Heart Failure Drugs market grow even more. Market participants are also taking a range of strategic initiatives to grow their worldwide footprint, with key market developments for Heart Failure Drugs such as new product launches, contractual agreements, mergers and acquisitions, increased investments, and collaboration with other organizations. Competitors in the Heart Failure Drugs industry escalating demand for effective drugs and treatment and their approval from authorized agencies to expand and survive in an increasingly competitive and rising market environment.

One of the primary business strategies adopted by manufacturers in the  Heart Failure Drugs industry to the expansion of pharmacies in hospitals and residential areas and the burgeoning e-commerce industry providing easy availability of medicines at affordable rates and the facility of secured online payment methods. In recent years, Heart Failure Drugs industry has provided medicine with some of the most significant benefits. The Heart Failure Drugs market major player such as Amgen Inc. (US), AstraZeneca (UK), Novartis AG (Switzerland), and others are working to expand the market demand by investing in research and development activities.

AstraZeneca is focused on the discovery, development and commercialization of prescription medicines in the areas of oncology and biopharmaceuticals, including cardiovascular heart disease. In May 2020, in order to lower the risk of cardiovascular (CV) death and heart failure hospitalisation in individuals with heart failure (NYHA classes II–IV) and decreased ejection fraction (HFrEF) both with and without type 2 diabetes, AstraZeneca's Farxiga (dapagliflozin) was approved in the US (T2D).

Also, Novartis AG uses innovative science and technology to address some of society's toughest health problems. Find new ways to deliver and develop treatments and make them available to as many people as possible. Novartis Entresto tablets, formerly known as LCZ696, reduce the risk of cardiovascular death and heart failure hospitalization in patients with chronic heart failure (NYHA classes II-IV) and reduced ejection fraction (HFrEF). It is usually given in combination with other heart failure treatments instead of an ACE inhibitor or another angiotensin receptor blocker (ARB). A low ejection fraction means the heart is not contracting with enough force, resulting in less blood being pumped out. In February 2019, Blackstone's Life Sciences and Novartis AG launched Anthos Therapeutics to develop drugs for cardiovascular heart failure.

Key Companies in the Heart Failure Drugs market includes

  • Amgen Inc. (US)

  • AstraZeneca (UK)

  • Novartis AG (Switzerland)

  • Boehringer Ingelheim International GmbH (Germany)

  • Johnson & Johnson Services (UK)

  • Bristol-Myers Squibb Company (US)

Heart Failure Drugs Industry Developments

February 2022 Empagliflozin's (Jardiance) label was expanded to include treatment for CHF. These SGLT2 inhibitor medications showed a 35% decrease in hospitalisation and strong cardioprotective benefits in clinical studies. Additionally, the medication class has shown clinical value in managing CHF in patients without diabetes.

February 2021 Forxiga, a medication used to treat adult heart failure with or without type-2 diabetes, has been approved in China, according to AstraZeneca.

January 2019 The FDA disclosed the approval granted regarding the addition of a disease indication which related to the prevention against the occurrence of VTE in acutely sick medical patients who were hospitalized, at risk. Thromboembolic complications were noticed in them. But no high risk was announced regarding bleeding, for rivaroxaban which is a Janssen Pharmaceutical product.

January 2019 An Indian business named Natco Pharma announced the release of the cardiovascular medicine valsartan-sacubitril, which is used to treat congestive heart failure. Valsartan-sacubitril is covered by a patent held by Novartis AG in India under the trade name Vymada.

Heart Failure Drugs Market Segmentation

Heart Failure Drugs Type Outlook

  • Beta-Blockers

  • ACE Inhibitors

  • Angiotensin-Receptor Neprilysin Inhibitors

  • Angiotensin Receptor Blockers

  • Diuretic

Heart Failure Drugs End-User Outlook

  • Hospitals

  • Specialty Centers

Heart Failure Drugs Regional Outlook

  • North America

    • US

    • Canada

  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe

  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific

  • Rest of the World

    • Middle East

    • Africa

    • Latin America

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